Sleep Regimen 3-in-1

Sleep Regimen 3-in-1

NOW4.5 (1,303 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 90 servings
Goals

Product analysis

59 out of 100

Sleep Regimen 3-in-1 may help with sleep timing and relaxation, with most support coming from melatonin and theanine.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality25

Theanine and melatonin preparations are unspecified, limiting a clear quality comparison. The named 5-HTP source does not establish a preparation advantage.

Ingredient Transparency75

All ingredient amounts are disclosed. The 5-HTP source is named, while theanine and melatonin preparations remain unspecified.

Value For Money77

The theanine amount compares favorably on cost. The 5-HTP and melatonin contributions offer more moderate value at the full serving price.

Customer Satisfaction78

Customer feedback is favorable across a substantial review pool. Those opinions describe satisfaction rather than establishing sleep improvements.

Product Focus65

Sleep and relaxation are the clearest uses for the short combination. Melatonin can conflict with daytime alertness, making daytime focus a less suitable purpose.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.18
Customer rating
4.5 · 1,303 ratings
Report analysis

Goals

Impact
Highest effect
A- Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Melatonin · 3 mgTheanine · 200 mg

Melatonin supports sleep timing and may shorten the time needed to fall asleep, while theanine may improve some reported sleep measures through calming. Theanine's supporting trial used repeated daily intake, so an immediate effect is uncertain. The 50 mg 5-HTP serving is below the 100 mg amount studied in a small older-adult trial; its limited findings were clearest in poor sleepers and do not establish a general benefit.

How this product is rated for Sleep Support

Ingredient fit88

Melatonin and theanine provide the clearest sleep connection. The smaller 5-HTP amount contributes less to the saved findings.
Goal fit
All three counted ingredients relate to sleep, although the product is linked to several other goals.
Dose adequacy
Melatonin and theanine meet their full reference ranges; 5-HTP receives partial amount-based credit at 50 mg per serving.

Pathways100

Sleep timing is the strongest contribution, with additional calming, stress-related and precursor-related coverage.
Depth
Melatonin provides the strongest coverage through sleep timing.
Breadth
Sleep timing, calming, stress regulation and precursor-related activity meet the saved coverage criterion; temperature-related onset activity remains smaller.

Evidence100

Melatonin supplies the strongest sleep evidence, with narrower support for theanine and very limited, population-specific findings for 5-HTP.
Evidence strength
Melatonin leads the evidence basis for sleep timing and onset.
Studied preparation
All three ingredients meet the saved preparation criterion; this does not make the lower 5-HTP amount equivalent to its trial regimen.

Formulation logic100

The three ingredients needs no missing partner, and no configured ingredient conflict was found.
Partner coverage
The included sleep-related ingredients can contribute without an additional required partner.
Conflicts
No configured sleep-opposing ingredient combination was identified in the supplied facts.
Effective doses
All ingredients counted here meet the saved minimum amount criterion; that does not guarantee a sleep effect.
Study evidence
5-HTP Supportive 1 study
Melatonin Supportive 181 studies
Theanine Supportive 8 studies
Stress Relief
Impact
High effect
A- Ingredient FitB+ PathwaysB EvidenceA+ Formulation Logic
Theanine · 200 mg

Theanine may ease tension and promote relaxation, although short-term calming does not establish durable stress relief. Melatonin adds a sleep-associated connection, with anxiety findings limited to selected procedural settings rather than general stress or cortisol reduction. The 5-HTP contribution is more conditional because its anxiety and stress findings include uncontrolled or hormonal evidence. Together, the supplied findings emphasize relaxation and sleep, without establishing an extra benefit from combining them.

How this product is rated for Stress Relief

Ingredient fit86

Theanine, melatonin and 5-HTP connect the formula mainly to relaxation and sleep.
Goal fit
Theanine, melatonin and 5-HTP connect the formula mainly to relaxation and sleep.
Dose adequacy
Theanine and melatonin meet their amount references; 5-HTP contributes partially.

Pathways80

Sleep recovery is the strongest finding, chiefly through melatonin alongside theanine. The main connections are calming and sleep; support for other stress aspects is limited.
Depth
Sleep recovery is the strongest finding, chiefly through melatonin alongside theanine.
Breadth
The main connections are calming and sleep; support for other stress aspects is limited.

Evidence77

Theanine provides the clearest direct tension findings. Melatonin and 5-HTP have narrower, context-dependent stress relevance.
Evidence strength
Theanine has the strongest direct tension evidence among these ingredients.
Studied preparation
The saved findings recognize the relevant preparations; this does not establish that the complete formula reproduces a trial regimen.

Formulation logic100

The relevant ingredients can contribute without a missing required partner. The supplied checks found no matched formulation conflict.
Partner coverage
No required partner is missing for the relevant ingredient contributions.
Conflicts
No listed ingredient combination triggered a conflict in the supplied checks.
Effective doses
All included ingredients reach the minimum amount threshold used for their contributions.
Study evidence
5-HTP Supportive 18 studies
Melatonin Supportive 21 studies
Theanine Supportive 16 studies
Mood Support
Impact
High effect
B- Ingredient FitD- PathwaysA EvidenceA+ Formulation Logic
5-HTP · 50 mg

Theanine may ease tension associated with acute stress, although sustained mood improvement is less certain. The serving provides 200 mg, the amount used in the supplied small acute trial. 5-HTP is a serotonin precursor, but the supplied older-adult study did not establish a mood advantage over its control group; that mechanism alone does not establish routine mood benefit.

How this product is rated for Mood Support

Ingredient fit70

The formula includes relevant ingredients alongside many ingredients aimed at other purposes, giving it a broad focus. The serving amounts fall short of several saved comparisons, limiting the amount-based findings without proving ineffectiveness.
Goal fit
The formula includes relevant ingredients alongside many ingredients aimed at other purposes, giving it a broad focus.
Dose adequacy
The serving amounts fall short of several saved comparisons, limiting the amount-based findings without proving ineffectiveness.

Pathways43

The strongest represented aspect is neural calming, with partial representation from the recognized ingredients. The findings concentrate on one aspect of mood support, leaving other aspects less represented.
Depth
The strongest represented aspect is neural calming, with partial representation from the recognized ingredients.
Breadth
The findings concentrate on one aspect of mood support, leaving other aspects less represented.

Evidence94

5-HTP provides the strongest recognized evidence here, subject to its population and preparation limitations. The saved result recognizes the qualifying preparations as studied; this does not establish benefit for every user.
Evidence strength
5-HTP provides the strongest recognized evidence here, subject to its population and preparation limitations.
Studied preparation
The saved result recognizes the qualifying preparations as studied; this does not establish benefit for every user.

Formulation logic100

The recognized ingredients have their required partners or can stand alone, and no listed conflict was matched. Their amounts meet the saved minimum comparisons.
Partner coverage
The recognized ingredients do not lack a required partner under the supplied checks; this does not demonstrate synergy.
Conflicts
No listed ingredient conflict was matched. This check does not establish medication compatibility.
Effective doses
All recognized ingredients meet the saved minimum amount comparison, which is not a proven clinical effect threshold.
Study evidence
5-HTP Supportive 9 studies
Theanine Supportive 12 studies
Brain Health
Impact
High effect
B+ Ingredient FitC- PathwaysB EvidenceA+ Formulation Logic

Theanine may help with calm attention, with limited support from small studies. Its 200 mg serving matches the comparison endpoint in the saved findings. Melatonin’s connection is through sleep timing and depends on indication and timing; its presence does not establish better next-day cognition or an extra benefit from combining it with theanine.

How this product is rated for Brain Health

Ingredient fit84

The ingredient selection connects to brain health, with serving amounts and the formula’s wider purpose shaping how focused that connection is.
Goal fit
The formula includes brain-relevant ingredients alongside a broader mix of ingredients and intended uses.
Dose adequacy
The recognized ingredients reach the saved amount references; those references do not guarantee cognitive benefit.

Pathways58

The strongest saved connection is stress and arousal regulation; this describes the ingredient grouping rather than a demonstrated brain-health outcome. One area reaches the saved coverage threshold, leaving the connection concentrated rather than broad.
Depth
The strongest saved connection is stress and arousal regulation; this describes the ingredient grouping rather than a demonstrated brain-health outcome.
Breadth
One area reaches the saved coverage threshold, leaving the connection concentrated rather than broad.

Evidence78

The saved evidence findings recognize ingredients and preparations, while the supplied scientific context limits expectations for general cognitive improvement.
Evidence strength
Theanine leads the saved evidence finding, while the supplied research context limits claims of broad cognitive improvement.
Studied preparation
The saved findings recognize the included preparations; this does not establish equivalence where the supplied scientific context distinguishes extracts or populations.

Formulation logic100

The saved findings identify no missing required partners or configured conflicts. Amount recognition does not itself establish an effective cognitive outcome.
Partner coverage
The recognized ingredients have no missing required partner in the saved findings; this does not establish an added benefit from combining them.
Conflicts
No configured conflict was identified. The caffeine-specific checks do not apply because no qualifying caffeine amount is established.
Effective doses
All ingredients included in this finding meet its minimum amount threshold, which is a comparison reference rather than a proven cognitive dose.
Study evidence
Melatonin Supportive 29 studies
Theanine Supportive 17 studies
Everyday Health
Impact
Moderate effect
B- Ingredient FitF PathwaysC- EvidenceA+ Formulation Logic

Melatonin at 3 mg provides the main assessed contribution through sleep and body-clock timing. The supplied findings do not establish a broad routine health benefit from this sleep-focused ingredient.

How this product is rated for Everyday Health

Ingredient fit71

The assessed contribution sits within a broader formula with other actives that add no independent contribution in these findings. The assessed amount fully meets the saved dose comparison.
Goal fit
The assessed contribution sits within a broader formula with other actives that add no independent contribution in these findings.
Dose adequacy
The assessed amount fully meets the saved dose comparison.

Pathways17

The strongest saved contribution concerns stress resilience and sleep, with limited coverage. No assessed health process reaches the saved coverage threshold.
Depth
The strongest saved contribution concerns stress resilience and sleep, with limited coverage.
Breadth
No assessed health process reaches the saved coverage threshold.

Evidence58

Melatonin provides the strongest saved evidence contribution at the assessed amount; its scope and limitations still apply. The ingredients meeting the saved amount threshold have preparations accepted by the saved evidence assessment.
Evidence strength
Melatonin provides the strongest saved evidence contribution at the assessed amount; its scope and limitations still apply.
Studied preparation
The ingredients meeting the saved amount threshold have preparations accepted by the saved evidence assessment.

Formulation logic100

The assessed ingredients can contribute independently or have their required companion present. No ingredient conflict was identified by the saved checks. All ingredients included in the saved dose check reach its minimum threshold.
Partner coverage
The assessed ingredients can contribute independently or have their required companion present.
Conflicts
No ingredient conflict was identified by the saved checks.
Effective doses
All ingredients included in the saved dose check reach its minimum threshold.
Study evidence
Melatonin Supportive 69 studies
Mental Focus
Impact
Lower effect
B- Ingredient FitC PathwaysB EvidenceB+ Formulation Logic
Theanine · 200 mg
Study evidence
Theanine Supportive 19 studies

Ingredients

IngredientAmount per servingScore
L-Theanine
200 mg 92
5-HTP (Griffonia simplicifolia Seed Extract)
50 mg 72
Melatonin
3 mg 52
Gluten Free Adults 18–50 Vegan Dairy Free Women Vegetarian
Report overview
Theanine · 200 mg OverallScore92
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 200 mg of L-theanine, with the amount disclosed separately. The whole-product price works out to about $0.09 per 100 mg of L-theanine.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The ingredient is identified as L-theanine. The saved facts do not identify a branded source or a separate purity claim.
Isomer Specificity (L-Theanine)
The ingredient is specified as L-theanine.
Branded Forms & Purity Standards
The saved facts do not identify a branded source or a separate purity claim.

Dose, Safety & Label Transparency100

Each serving provides 200 mg of L-theanine. The amount and source are disclosed separately.
Theanine Dosage Efficacy
Each serving provides 200 mg of L-theanine.
Label Transparency & Blends
The 200 mg of L-theanine and its source are disclosed separately.

Value100

The whole-product price is about $0.09 per 100 mg of L-theanine.
Price per 100mg L-Theanine
The whole-product price is about $0.09 per 100 mg of L-theanine.
Melatonin · 3 mg OverallScore52
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
Each capsule supplies 3 mg of melatonin. A whole-product serving costs about $0.19.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

The saved facts show no independent purity verification claim.
Third-Party Purity Verification
No USP, sports-certification or other independent lab claim is recorded in the available facts.

Dose, Safety & Label Transparency100

Each serving provides 3 mg of melatonin, a modest amount.
Physiological Dosing Alignment
The declared melatonin amount is 3 mg per serving.

Value60

The whole-product serving costs about $0.19, a moderate serving cost.
Price Per Serving Efficiency
The price is about $0.19 per whole-product serving.
B- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyC Value
Each serving supplies 50 mg of 5-HTP from Griffonia simplicifolia. The label includes a warning about interactions with certain serotonin-affecting medicines.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The available information identifies Griffonia simplicifolia as the source but does not give a 5-HTP standardization percentage.
Botanical Source & Standardization
The available information identifies Griffonia simplicifolia as the source but does not give a 5-HTP standardization percentage.

Dose, Safety & Label Transparency79

Each serving supplies 50 mg of 5-HTP. The label includes a warning about interactions with certain serotonin-affecting medicines.
Dosage Potency & Range
Each serving supplies 50 mg of 5-HTP.
Safety Warnings & Label Clarity
The label includes a warning about interactions with certain serotonin-affecting medicines.

Value60

Whole-product servings cost about $0.38 per 100 mg of 5-HTP, a moderate cost on this ingredient-based measure.
Price per 100mg 5-HTP
Whole-product servings cost about $0.38 per 100 mg of 5-HTP, a moderate cost on this ingredient-based measure.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  2. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  3. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  4. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  5. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  6. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  7. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  8. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  9. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  10. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  11. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  12. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  13. Melatonin for preventing and treating jet lag.
    Herxheimer A; Petrie KJ · The Cochrane database of systematic reviews · 2001
    Systematic review10 studies pooledEveryday Health forMelatonin
  14. Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.
    Schroder CM; Malow BA; Maras A; Melmed RD; Findling RL; Breddy J; Nir T; Shahmoon S; Zisapel N; Gringras P · Journal of autism and developmental disorders · 2019
    Randomized trial125 participantsEveryday Health forMelatonin
  15. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
    Fatemeh G; Sajjad M; Niloufar R; Neda S; Leila S; Khadijeh M · Journal of neurology · 2022
    Meta-analysis23 studies pooledEveryday Health forMelatonin
  16. Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
    Choi K; Lee YJ; Park S; Je NK; Suh HS · Sleep medicine reviews · 2022
    Meta-analysis24 studies pooledEveryday Health forMelatonin
  17. Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    Leerasiri P; Pariyaeksut P; Hengrasmee P; Asumpinwong C · International urogynecology journal · 2023
    Randomized trial60 participantsEveryday Health forMelatonin
  18. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsMental Focus Productivity Boost Stress Relief forTheanine
  19. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  20. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
    Jangid P; Malik P; Singh P; Sharma M; Gulia AK · Asian journal of psychiatry · 2013
    Randomized trial70 participantsMood Support for5-HTP