Coenzyme Q10 100 mg

Coenzyme Q10 100 mg

Source Naturals4.8 (198 ratings)
Format:Softgel Quantity: 60 Softgel(s) · 60 servings
Goals
$13.25 $0.22 per serving

Product analysis

76 out of 100

Coenzyme Q10 100 mg may support blood-vessel function and offers favorable value. The evidence concerns selected populations and does not establish a dependable everyday energy boost.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality52

Natural vitamin E is clearly identified as a favorable form choice. CoQ10 is named as ubiquinone, though its preparation quality remains uncertain.

Ingredient Transparency100

Both ingredient amounts and forms are disclosed, making the formula straightforward to compare. CoQ10 is specifically identified as ubiquinone rather than left unnamed.

Value For Money100

CoQ10 and vitamin E both compare favorably on cost. That makes the combination economical for its declared ingredients.

Customer Satisfaction75

Customer ratings are positive, with a modest review base. More feedback would give a firmer picture of how widely that satisfaction applies.

Product Focus64

The clearest potential benefit concerns blood-vessel function, with more limited evidence for fatigue support. Changes in blood markers do not establish broad cardiovascular protection or symptom relief.

Format
Softgel
Container
60 Softgel(s)
Per serving
$0.22
Customer rating
4.8 · 198 ratings
Report analysis

Goals

Heart Health
Impact
High effect
B- Ingredient FitD+ PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Cardiovascular Support
Impact
High effect
B- Ingredient FitD+ PathwaysA- EvidenceA- Formulation Logic
Coenzyme Q-10 · 100 mgVitamin E · 5 IU
Study evidence
Vitamin E Mixed 79 studies
Longevity
Impact
Lower effect
C Ingredient FitF PathwaysF EvidenceA- Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Vitamin E Supportive 19 studies
Inflammation
Impact
Moderate effect
C- Ingredient FitF PathwaysA EvidenceA- Formulation Logic
Coenzyme Q-10 · 100 mgVitamin E · 5 IU
Study evidence
Vitamin E Supportive 20 studies
Energy
Impact
Moderate effect
C- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Metabolism Support
Impact
Moderate effect
C- Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence

Ingredients

IngredientAmount per servingScore
Vitamin E (D-Alpha-Tocopherol)
5 IU 50
Coenzyme Q10 (Ubiquinone)
100 mg 72
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 100 mg of CoQ10 at a low for the amount and form cost. It uses ubiquinone, which the body converts to ubiquinol. The amount is clearly stated.
How this ingredient is rated

Active Ingredient Quality & Bioavailability48

It uses ubiquinone, which the body converts to ubiquinol. No liposomal, micellar, nano-emulsion or black pepper extract claim is recorded.
Molecular Form: Ubiquinol vs. Ubiquinone
It uses ubiquinone, which the body converts to ubiquinol.
Formulation & Absorption Enhancers
No liposomal, micellar, nano-emulsion or black pepper extract claim is recorded.

Dose, Safety & Label Transparency83

100 mg of ubiquinone is provided per serving. The amount is stated and the available ingredient information flags no listed problematic additives or standard fillers.
Clinical Dosage Alignment
100 mg of ubiquinone is provided per serving.
Label Transparency & Fillers
The amount is stated and the available ingredient information flags no listed problematic additives or standard fillers.

Value100

The cost per 100 mg of ubiquinone is low.
Price Per Effective Serving
The cost per 100 mg of ubiquinone is low.
D Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value
A serving supplies 5 IU of vitamin E at a low cost per serving. D-Alpha-Tocopherol is a natural form of vitamin E. The broader mix of tocopherols and tocotrienols is not listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability46

D-Alpha-Tocopherol is a natural form of vitamin E. A broader mix of tocopherols and tocotrienols is not listed.
Natural (d-alpha) vs. Synthetic (dl-alpha)
D-Alpha-Tocopherol is a natural form of vitamin E.
Mixed Tocopherol Isomer Diversity
A mixed-tocopherol complex is not listed.
Tocotrienol Complex Inclusion
Tocotrienols are not listed.

Dose, Safety & Label Transparency29

A serving provides 5 IU of vitamin E. The form is named as D-Alpha-Tocopherol; individual isomer amounts are not provided.
Therapeutic Dosage Range
A serving provides 5 IU of vitamin E.
Label Transparency and Isomer Specificity
The form is named as D-Alpha-Tocopherol; individual isomer amounts are not provided.

Value100

The cost per serving is low.
Cost per Natural-Form Therapeutic Serving
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  7. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  8. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  9. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  10. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E
  11. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  12. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  13. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  14. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  15. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  16. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  17. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  18. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Support forCoenzyme Q-10
  19. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  20. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsInflammation forCoenzyme Q-10