CoQ10 with PQQ

CoQ10 with PQQ

Lake Avenue Nutrition4.8 (12,935 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$15.24 $0.25 per serving
iHerbLowest$15.24iHerb$15.24

Product analysis

67 out of 100

CoQ10 with PQQ may support some measures of heart and blood-vessel health through its CoQ10, although results are mixed. The extra benefit from PQQ remains uncertain.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Both ingredients have named preparations, making their identity clear. Their names alone do not establish better absorption or an advantage from combining them.

Ingredient Transparency100

Both amounts and preparations are fully disclosed. That makes the combination easier to compare with single-ingredient options.

Value For Money53

The CoQ10 portion offers reasonable value at the full serving cost. PQQ value remains uncertain, so the combination is harder to judge as a deal.

Customer Satisfaction93

Customer feedback is very positive across a large number of ratings. Those opinions do not establish effectiveness or safety.

Product Focus66

CoQ10 provides the clearer link to heart support and normal energy production in cells. PQQ adds a related ingredient, but broader benefits from the pairing remain uncertain.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.25
Customer rating
4.8 · 12,935 ratings
Report analysis

Goals

Longevity
Longevity
Impact
Moderate effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B- Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Heart Health
Heart Health
Impact
High effect
B- Ingredient FitD+ PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Energy
Energy
Impact
High effect
B- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Metabolism Support
Metabolism Support
Impact
Moderate effect
C- Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence
Inflammation
Inflammation
Impact
Moderate effect
D+ Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg
Study evidence

Ingredients

IngredientAmount per servingScore
CoQ10 (Ubiquinone)
 100 mg 64
Pyrroloquinoline Quinone (Pyrroloquinoline Quinone Disodium Salt)
 10 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 (Ubiquinone) · 100 mg OverallScore64
D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value
View ingredientView products
87 Performance

Extra Strength Ubiquinol 200 mg

NOW

Ingredient quality is better supported by 200 mg ubiquinol, the reduced CoQ10 form, keeping the alternative closely aligned with the CoQ10 collection. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.

87 Performance

Mega CoQ10 Ubiquinol 100 mg

Qunol

Ingredient quality is better supported by 100 mg ubiquinol, the reduced CoQ10 form, keeping the alternative closely aligned with the CoQ10 collection. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.

87 Performance

QH-absorb 100 mg

Jarrow Formulas

Ingredient quality is better supported by 100 mg ubiquinol, the reduced CoQ10 form, keeping the alternative closely aligned with the CoQ10 collection. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.

84 Budget

CoQ10 100 mg

Best Naturals

100 mg ubiquinone retains the core ingredient at a lower serving cost. The focused label keeps the comparison close to the original while making the CoQ10 form straightforward to assess.

85 Budget

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best

100 mg ubiquinone retains the core ingredient at a lower serving cost. Black-pepper extract adds an absorption-oriented companion ingredient, though medicine interactions may need consideration.

84 Budget

CoQ10 100 mg

California Gold Nutrition

100 mg ubiquinone retains the core ingredient at a lower serving cost. The focused label keeps the comparison close to the original while making the CoQ10 form straightforward to assess.

86 Value

Ubiquinol 100 mg

NOW

100 mg ubiquinol, the reduced CoQ10 form combines a relevant CoQ10 serving with favorable value evidence. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.

85 Value

Mega Ubiquinol CoQ10 100 mg

Qunol

100 mg ubiquinol, the reduced CoQ10 form combines a relevant CoQ10 serving with favorable value evidence. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.

87 Value

QH-absorb 100 mg

Jarrow Formulas

100 mg ubiquinol, the reduced CoQ10 form combines a relevant CoQ10 serving with favorable value evidence. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.

Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  7. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  8. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  9. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  10. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  11. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  12. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  13. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Support forCoenzyme Q-10
  14. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  15. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsInflammation forCoenzyme Q-10
  16. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsInflammation forCoenzyme Q-10
  17. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledInflammation forCoenzyme Q-10
  18. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledInflammation forCoenzyme Q-10
  19. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsInflammation forCoenzyme Q-10
  20. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewLongevity forCoenzyme Q-10