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Liposomal Vitamin C 500 mg

4.8
★ ★ ★ ★ ★
(8870 ratings)
Vitamin C 500 mg
Product Image
Score70
A strong liposomal vitamin C option with a sensible amount and clear carrier quantity. It remains a focused single-nutrient product rather than a broad immune, skin, or vision formula.
How scoring works
Capsule
Quantity:100 VegCap(s) • (100 servings)
Goals:
General Health
Immunity
Anti-Inflammatory Support
Skin Health

Score 70

A strong liposomal vitamin C option with a sensible amount and clear carrier quantity. It remains a focused single-nutrient product rather than a broad immune, skin, or vision formula.
How scoring works
$24.99($0.24 per serving)
Vitacost
$ 29.59
iHerb
$ 29.59
Pure Formulas
$ 29.59
Walmart
$ 24.99
Pure Formulas
$ 29.59
Report prices

Analysis

The 500 mg liposomal ascorbic acid serving provides focused vitamin C support for antioxidant defenses, immune function, and collagen formation. The amount is substantial without reaching the unusually high levels used by several alternatives.

A quantified liposomal blend gives the delivery claim a visible formulation basis. The short ingredient panel is easy to assess, although the product is not described as buffered and the exact phospholipid composition is not supplied.

The capsule fits users who want an upgraded vitamin C format without a complex blend. It supports several foundational functions, but it does not include zinc, vitamin D, carotenoids, collagen, or other ingredients needed for broader goal coverage.

Who is it for
  • Adults seeking an enhanced vitamin C format
  • Users who prefer capsules over powders or liquids
  • People wanting a moderate high-potency serving
Best for
  • Focused antioxidant support
  • Normal immune function
  • Collagen synthesis support

Pros

  • Liposomal form with quantified blend
  • Well-targeted vitamin C amount
  • Short and focused formula
  • Convenient capsule format

Cons

  • No complementary immune nutrients
  • Not explicitly buffered
  • Phospholipid composition is not detailed
  • Limited pathway breadth

Warnings

  • The 500 mg serving may still cause digestive discomfort in sensitive users.
  • The product does not disclose enough carrier detail to compare liposome quality precisely.
  • People with a history of calcium oxalate stones should be cautious with sustained high vitamin C intake.

Nutrient quality

86 Highest impact

The liposomal form and moderate amount are well aligned with vitamin C supplementation. Unclear blend composition prevents a full judgment of the delivery system.

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Ingredient transparency

53 Moderate impact

The vitamin C form and amount are clear. Hidden liposomal components, missing use directions, and absent excipients substantially reduce transparency.

.

Customer satisfaction

73 High impact

The aggregate satisfaction signal is strong and supported by extensive volume. Missing review details prevent assessment of recurring complaints or purpose fit.

.

Value for money

71 High impact

The specialized delivery form provides some justification for its moderate serving value. Incomplete blend disclosure makes it difficult to confirm an advantage over simpler options.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin C · 500 mg

Vitamin C directly supports antioxidant defenses, immune function, and collagen formation. Its foundational nutritional role is supported by established science.

The 500 mg amount provides a substantial and well-targeted vitamin C serving. Liposomal ascorbic acid and a quantified lipid blend provide strong delivery quality and disclosure.

Study evidence
Vitamin C Supportive 56 studies
Immunity
Immunity
Impact
Highest effect
A Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin C · 500 mg

Liposomal vitamin C provides a direct immune nutrient in an enhanced delivery format. The 500 mg amount reaches the targeted minimum while keeping the formula compact.

The lipid blend is quantified and the ingredient list avoids distracting extras. Coverage remains narrow because no zinc, vitamin D, barrier nutrient, or botanical immune pathway is included.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Cellular Defense
Anti-Inflammatory Support
Impact
High effect
B- Goal FitA- Strength of SupportD CoverageA Formula Quality
Vitamin C · 500 mg

Liposomal vitamin C at 500 mg provides a meaningful antioxidant dose with enhanced delivery potential. The quantified lipid blend improves confidence that the liposomal claim has a formulation basis.

A focused two-ingredient design avoids unnecessary additions and gives strong depth in one pathway. The product does not address inflammatory enzymes, immune nutrients, or multiple antioxidant systems.

Study evidence
Vitamin C Supportive 50 studies
Skin Health
Skin Health
Impact
High effect
C Goal FitB Strength of SupportB- CoverageB Formula Quality
Vitamin C · 500 mg

Vitamin C provides a useful but incomplete connection to skin health. The main relevant amounts appear substantial enough to contribute in practice.

Coverage reaches collagen synthesis and oxidative defense. Some pathways remain less complete than the formula’s strongest area.

Study evidence
Vitamin C Supportive 53 studies
Vision Support
Macular and Blue Light Defense
Vision Support
Impact
Moderate effect
F Goal FitB+ Strength of SupportF CoverageB- Formula Quality
Vitamin C · 500 mg

Liposomal vitamin C provides antioxidant support but no direct macular pigment or retinal lipid. Vitamin C belongs to established ocular antioxidant frameworks, though isolated supplementation is not comprehensive vision support.

The product covers only antioxidant defense and omits lutein, zeaxanthin, zinc, copper, vitamin E, and DHA. The simple vitamin C plus liposomal carrier design is coherent.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Liposomal Ascorbic Acid)
 500 mg
Liposomal Blend
241 mg
Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Vitamin C (Liposomal Ascorbic Acid) · 500 mg OverallScore91
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Liposomal ascorbic acid provides the strongest delivery technology in the group while keeping the dose in the preferred range. The short ingredient panel and clearly quantified lipid blend support purity and transparency, although the product is not explicitly buffered. Its cost per gram remains good for a premium liposomal form.

View ingredientView products
Loading alternative details
82 Performance

Liposomal Vitamin C 1000 mg

SunLipid
Ingredient and delivery quality improve with 1,000 mg of vitamin C as sodium ascorbate with a 1,000 mg phospholipid complex and 500 mg of MCTs. Compared with the original 500 mg liposomal formula, the explicitly disclosed delivery matrix provides clearer liposomal support than a basic vitamin C formula, although the disclosed sodium contribution may matter on a sodium-restricted diet.
84 Performance

Ester-C 500 mg With Citrus Bioflavoinds

American Health
Ingredient and delivery quality improve with 1,000 mg of buffered Ester-C with a broad citrus bioflavonoid complex. Compared with the original 500 mg liposomal formula, the formula adds several named citrus compounds while maintaining a substantial vitamin C amount, although the repeated complex entries make the exact internal amounts difficult to interpret.
86 Performance

Ester-C Plus 1000 mg Vitamin C

Solgar
Ingredient and delivery quality improve with 1,000 mg of buffered Ester-C with 108 mg of calcium and 200 mg of citrus bioflavonoids. Compared with the original 500 mg liposomal formula, the substantial buffered dose and compatible bioflavonoids broaden support beyond plain ascorbic acid, although complete excipient details are not supplied.
89 Budget

Pure Buffered Calcium Ascorbate

NOW
A lower serving cost comes with 890 mg of vitamin C as buffered calcium ascorbate with 100 mg of calcium, compared with the original 500 mg liposomal formula. the mineral-bound form may be gentler than plain ascorbic acid and keeps the active formula focused, although the full inactive-ingredient panel is not supplied.
84 Budget

Ester-C 500 mg With Citrus Bioflavoinds

American Health
A lower serving cost comes with 1,000 mg of buffered Ester-C with a broad citrus bioflavonoid complex, compared with the original 500 mg liposomal formula. the formula adds several named citrus compounds while maintaining a substantial vitamin C amount, although the repeated complex entries make the exact internal amounts difficult to interpret.
88 Budget

Buffered Gold C

California Gold Nutrition
A lower serving cost comes with 1,000 mg of vitamin C as sodium ascorbate with 130 mg of sodium, compared with the original 500 mg liposomal formula. the simple buffered formula provides a full amount with no unrelated active ingredients, although the sodium contribution needs consideration on a restricted diet.
89 Value

C-500 Calcium Ascorbate-C

NOW
A stronger quality-to-cost balance comes from 500 mg of vitamin C as calcium ascorbate with 55 mg of calcium and 10 mg of citrus bioflavonoids. Compared with the original 500 mg liposomal formula, the buffered form supports stomach comfort while retaining a practical daily amount, while the bioflavonoid addition is small.
88 Value

Sodium Ascorbate

NutriBiotic Immunity
A stronger quality-to-cost balance comes from 1,100 mg of vitamin C as sodium ascorbate with 120 mg of sodium. Compared with the original 500 mg liposomal formula, the fully buffered powder provides a substantial, clearly disclosed amount, while careful measuring and sodium accounting remain important.
86 Value

C

Swanson
A stronger quality-to-cost balance comes from 1,000 mg of calcium ascorbate with 120 mg of calcium and 200 mg of citrus bioflavonoids. Compared with the original 500 mg liposomal formula, the buffered form and meaningful bioflavonoid amount offer a broader formula than plain ascorbic acid, while complete excipient details are not supplied.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses.
    Xu K; Peng R; Zou Y; Jiang X; Sun Q; Song C · International journal of food sciences and nutrition · 2022
    Meta-analysis76 studies pooledGeneral Health forVitamin C
  2. Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment: JACC Focus Seminar.
    Jenkins DJA; Spence JD; Giovannucci EL; Kim YI; Josse RG; Vieth R; Sahye-Pudaruth S; Paquette M; Patel D; Blanco Mejia S; Viguiliouk E; Nishi SK; Kavanagh M; Tsirakis T; Kendall CWC; Pichika SC; Sievenpiper JL · Journal of the American College of Cardiology · 2021
    Meta-analysisGeneral Health forVitamin C
  3. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  4. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  5. The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.
    SeyedAlinaghi S; Shahidi R; Mojdeganlou H; Akhtaran FK; Maroufi SF; Maroufi SP; Mirzapour P; Karimi A; Khodaei S; Pour MM; Mehraeen E; Dadras O · Journal of health, population, and nutrition · 2024
    Systematic review28 studies pooledImmunity forVitamin C
  6. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  7. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage.
    Fitzpatrick RE; Rostan EF · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2002
    Non-randomized trial10 participantsSkin Health forVitamin C
  8. What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
    Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
    Systematic review27 studies pooledVision Support forVitamin C
  9. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin C
  10. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  11. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  12. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  13. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  14. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  15. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  16. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  17. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  18. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  19. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  20. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  21. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  22. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  23. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  24. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  25. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  26. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  27. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  28. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  29. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  30. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  31. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  32. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C