Product Image

Godzilla Pre-Workout Blackberry Lemonade

Ryse
4.8
★ ★ ★ ★ ★
(230 ratings)
Theobromine 200 mg
Sodium 610 mg
Choline 640 mg
Caffeine 350 mg
Potassium 200 mg
Product Image
Score62

A heavily dosed performance pre-workout with meaningful creatine, beta-alanine, betaine, choline, and electrolytes. The extreme stimulant load and opaque pump blend are major trade-offs.

How scoring works
Quantity:732 Gram(s) • (20 servings)
Goals:
Fitness
Energy
Muscle Gain
Mental Focus
Metabolism Boost
Productivity Boost
Weight Loss
Cognitive Support

Score 62

A heavily dosed performance pre-workout with meaningful creatine, beta-alanine, betaine, choline, and electrolytes. The extreme stimulant load and opaque pump blend are major trade-offs.

How scoring works
$56.99($2.84 per serving)
iHerb
$ 56.99
iHerb
$ 56.99
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Analysis

The full serving includes 5 g creatine monohydrate, 6.4 g beta-alanine, 5 g betaine, 640 mg elemental choline, and 610 mg sodium. Those amounts provide substantial support for strength, fatigue resistance, focus, and training hydration.

Immediate and extended-release caffeine total 400 mg, with another 200 mg theobromine. The 11 g pump blend does not disclose its internal amounts, which limits assessment despite the heavily dosed named ingredients.

The formula suits experienced stimulant users training early enough to protect sleep. It is a poor fit for caffeine-sensitive users, people seeking a transparent pump formula, or anyone with a milk allergy because VasoDrive-AP is casein-derived.

Who is it for
  • Experienced stimulant users
  • Adults seeking a high-dose all-in-one pre-workout
  • Athletes who tolerate beta-alanine and high sodium
Best for
  • Acute training energy
  • Strength and power support
  • Workout focus and hydration

Pros

  • Provides 5 g creatine monohydrate
  • Substantial beta-alanine and betaine amounts
  • Strong choline and electrolyte doses
  • Immediate and extended-release caffeine
  • Clearly states most central actives

Cons

  • Pump blend hides its internal amounts
  • Very high stimulant load
  • Only 20 servings
  • Choline bitartrate is less brain-targeted than citicoline or Alpha-GPC
  • Poor fit for general wellness or detoxification

Warnings

  • The 400 mg combined caffeine amount reaches the usual healthy-adult daily boundary
  • Do not combine a full serving with other caffeine or stimulants
  • The added 200 mg theobromine may increase jitters, nausea, rapid heartbeat, or sleep disruption
  • VasoDrive-AP is casein-derived and is unsuitable for people with a milk allergy
  • A full serving may cause marked beta-alanine tingling
  • The 610 mg sodium amount should be considered by people limiting sodium intake

Nutrient quality

74 High impact

Creatine monohydrate, betaine, beta-alanine, choline, caffeine, and pump-support ingredients provide a potent performance design. High caffeine, unusually large beta-alanine and betaine amounts, and an opaque pump blend make the formula aggressive rather than broadly balanced.

Ingredient transparency

56 Moderate impact

Most major performance ingredients have clear amounts and specific names. The large pump blend hides its components, while duplicated choline entries, non-active powder ingredients, and complete use directions are missing.

Customer satisfaction

67 High impact

The average rating is excellent and supported by a moderate review count. No detailed reviews are supplied to assess recurring complaints about taste, tingling, stimulation, or crashes.

Value for money

50 Lower impact

Large performance doses provide substantial material in each serving. A very short supply, premium positioning, aggressive stimulation, and an opaque pump blend make practical value weak.

Report analysis

Goals

Fitness
Impact
Highest effect
A+ Goal FitA Strength of SupportA+ CoverageA- Formula Quality
Creatine · 5 Gram(s)Betaine Anhydrous · 5 Gram(s)Beta-Alanine · 6.4 Gram(s)Caffeine · 50 mg

Creatine, beta-alanine, betaine, caffeine, choline, electrolytes, and theobromine provide deep support for power, fatigue resistance, focus, and hydration. The central actives are supplied at substantial and clearly disclosed amounts.

The combined caffeine amount reaches the usual healthy-adult daily limit, and added theobromine can increase jitters, rapid heartbeat, nausea, or sleep disruption. The potent design suits experienced stimulant users better than caffeine-sensitive athletes.

Study evidence
Caffeine Supportive 255 studies
Creatine Supportive 143 studies
Sodium Supportive 96 studies
Energy
Impact
Highest effect
A+ Goal FitA Strength of SupportA CoverageB+ Formula Quality
Potassium · 200 mgCaffeine · 50 mgCreatine · 5 Gram(s)

High-dose caffeine, creatine, beta-alanine, betaine, choline, and theobromine create a potent pre-workout for acute energy and performance. Immediate and extended-release caffeine support both rapid and longer-lasting stimulation.

The combined caffeine amount reaches the usual healthy-adult daily limit, and added theobromine can increase jitters, rapid heartbeat, nausea, or sleep disruption. A full serving is therefore a poor fit for caffeine-sensitive users or use late in the day.

Study evidence
Caffeine Supportive 68 studies
Creatine Supportive 49 studies
Theobromine Adverse 1 study
Muscle Gain
Impact
Highest effect
A Goal FitA- Strength of SupportA CoverageB- Formula Quality
Creatine · 5 Gram(s)Caffeine · 50 mgBeta-Alanine · 6.4 Gram(s)

Five grams of creatine monohydrate anchors a potent strength formula, while beta-alanine and betaine add substantial fatigue and power support. The ingredient set covers several pathways relevant to productive hypertrophy training.

The large pump blend hides its internal amounts, and beta-alanine and betaine exceed many common daily protocols. Four hundred milligrams of combined caffeine may cause jitteriness, a rapid heartbeat, or sleep disruption that can impair recovery.

Study evidence
Caffeine Supportive 31 studies
Creatine Supportive 136 studies
Mental Focus
Impact
Highest effect
A Goal FitB+ Strength of SupportB+ CoverageB Formula Quality
Choline · 1.6 Gram(s)Creatine · 5 Gram(s)Caffeine · 50 mg

The combination of immediate and extended-release caffeine provides strong acute alertness, while theobromine and a substantial choline amount broaden the cognitive support. Exact active amounts make the stimulant load and likely effects relatively easy to assess.

The full serving combines a very high total caffeine load with theobromine, which may cause jitteriness, rapid heartbeat, nausea, or sleep disruption in sensitive users. Choline bitartrate is less targeted to brain use than citicoline or Alpha-GPC, and the physical-performance ingredients add bulk without directly improving focus.

Study evidence
Caffeine Supportive 128 studies
Choline Supportive 22 studies
Metabolism Boost
Impact
Highest effect
A- Goal FitA- Strength of SupportB- CoverageB Formula Quality
Creatine · 5 Gram(s)Caffeine · 50 mg

Immediate and extended-release caffeine directly raise alertness and may temporarily increase energy expenditure and fat oxidation. Creatine and betaine can support training output, but they do not replace broader thyroid, glycemic, or mitochondrial support.

The label makes the principal amounts visible, although the total caffeine must be added across two entries. The combined stimulant load is very high, so a full serving should not be combined with other caffeine and may cause rapid heartbeat, anxiety, or sleep disruption.

Study evidence
Caffeine Disputed 40 studies
Creatine Supportive 21 studies
Productivity Boost
Impact
High effect
B+ Goal FitB Strength of SupportB- CoverageC- Formula Quality
Creatine · 5 Gram(s)Caffeine · 50 mg

High-dose immediate and extended-release caffeine provides strong acute alertness, while choline and creatine may support mental performance. The stimulant amount is aggressive and is not balanced with a calming ingredient such as theanine.

Workout actives dominate the formula, so much of its breadth does not improve desk-based focus. Clear dosing supports confidence in the acute effect, but the formula favors stimulation over balanced productivity.

Study evidence
Caffeine Supportive 108 studies
Creatine Supportive 16 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s)
Choline (Choline Bitartrate)
640 mg
Sodium
610 mg
Potassium
200 mg
RYSE Pump Fuel
11 Gram(s)
Beta Alanine
6.4 Gram(s)
Betaine Anhydrous
5 Gram(s)
Creatine Monohydrate
5 Gram(s)
Choline Bitartrate
1.6 Gram(s)
pink Himalayan Sea Salt
500 mg
Caffeine Anhydrous
350 mg
VasoDrive-AP (Casein Tripeptides, Hydrolyzed)
300 mg
Theobromine
200 mg
ZumXR (extended release Caffeine)
50 mg
Thinkamine (Vincamine)
20 mg
Adults 18–50 Women
Report overview
Theobromine · 200 mg OverallScore86
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

The exact standalone theobromine amount is effective and easy to verify. A broad, heavily dosed performance blend partly offsets the high serving cost, while excipient details remain unavailable. Combining 200 mg theobromine with 400 mg total caffeine may increase jitteriness, nausea, headache, or palpitations.

Sodium · 610 mg OverallScore84
B Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The 610 mg sodium serving is well aligned with fitness hydration and comes from named Pink Himalayan sea salt. Supporting electrolytes have clear amounts, but their chemical forms and any trace-mineral support are not identified. The broader pre-workout formula justifies neutral value treatment, while electrolyte amounts remain clearly disclosed.

B Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Choline bitartrate is useful for general choline intake but is less targeted to cognitive support than Alpha-GPC or citicoline. Its 640 mg elemental choline serving supplies a robust amount. The serving takes more than one scoop and remains costly despite its robust dose.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Caffeine administration at night during extended wakefulness effectively mitigates performance impairment but not subjective assessments of fatigue and sleepiness.
    Paech GM; Banks S; Pajcin M; Grant C; Johnson K; Kamimori GH; Vedova CB · Pharmacology, biochemistry, and behavior · 2017
    Randomized trial24 participantsEnergy forCaffeine
  2. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  3. Effect of Caffeine on Golf Performance and Fatigue during a Competitive Tournament.
    Mumford PW; Tribby AC; Poole CN; Dalbo VJ; Scanlan AT; Moon JR; Roberts MD; Young KC · Medicine and science in sports and exercise · 2016
    Randomized trial12 participantsEnergy forCaffeine
  4. Effects of Caffeine Intake on Cognitive Performance Related to Total Sleep Deprivation and Time on Task: A Randomized Cross-Over Double-Blind Study.
    Quiquempoix M; Sauvet F; Erblang M; Van Beers P; Guillard M; Drogou C; Trignol A; Vergez A; Léger D; Chennaoui M; Gomez-Merino D; Rabat A · Nature and science of sleep · 2022
    Randomized trial24 participantsEnergy forCaffeine
  5. No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
    Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial56 participantsEnergy forCaffeine
  6. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features.
    Juliano LM; Griffiths RR · Psychopharmacology · 2005
    Systematic review66 studies pooledEnergy forCaffeine
  7. International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance.
    Grgic J; Pedisic Z; Saunders B; Artioli GG; Schoenfeld BJ; McKenna MJ; Bishop DJ; Kreider RB; Stout JR; Kalman DS; Arent SM; VanDusseldorp TA; Lopez HL; Ziegenfuss TN; Burke LM; Antonio J; Campbell BI · Journal of the International Society of Sports Nutrition · 2021
    Guideline / consensusFitness forSodium
  8. Sodium Hyperhydration Improves Performance With No Change in Thermal and Cardiovascular Strain in Female Cyclists Exercising in the Heat Across the Menstrual Cycle.
    Convit L; Orellana L; Périard JD; Carr AJ; Warmington S; Beaugeois M; Abraham A; Snipe RMJ · International journal of sport nutrition and exercise metabolism · 2025
    Randomized trial12 participantsFitness forSodium
  9. The effect of chronic progressive-dose sodium bicarbonate ingestion on CrossFit-like performance: A double-blind, randomized cross-over trial.
    Durkalec-Michalski K; Zawieja EE; Podgórski T; Łoniewski I; Zawieja BE; Warzybok M; Jeszka J · PloS one · 2018
    Randomized trial21 participantsFitness forSodium
  10. Negligible benefit of oral single-dose sodium bicarbonate on continuous running performance: systematic review with meta-analysis of randomized, double-blind, placebo-controlled trials.
    Miller LE; Bhattacharyya R; Katz SJ; Bhattacharyya M; Herbert WG · Journal of the International Society of Sports Nutrition · 2025
    Meta-analysis126 participants11 studies pooledFitness forSodium
  11. Increased blood pH but not performance with sodium bicarbonate supplementation in elite rugby union players.
    Cameron SL; McLay-Cooke RT; Brown RC; Gray AR; Fairbairn KA · International journal of sport nutrition and exercise metabolism · 2010
    Randomized trial25 participantsFitness forSodium
  12. Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers.
    Knott V; de la Salle S; Choueiry J; Impey D; Smith D; Smith M; Beaudry E; Saghir S; Ilivitsky V; Labelle A · Pharmacology, biochemistry, and behavior · 2016
    Randomized trial24 participantsMental Focus forCholine
  13. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort.
    Poly C; Massaro JM; Seshadri S; Wolf PA; Cho E; Krall E; Jacques PF; Au R · The American journal of clinical nutrition · 2012
    Cohort study1,391 participantsMental Focus forCholine
  14. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly.
    Fioravanti M; Yanagi M · The Cochrane database of systematic reviews · 2005
    Meta-analysis14 studies pooledMental Focus forCholine
  15. Associations between maternal folate status and choline intake during pregnancy and neurodevelopment at 3-4 years of age in the Alberta Pregnancy Outcomes and Nutrition (APrON) study.
    Irvine N; England-Mason G; Field CJ; Letourneau N; Bell RC; Giesbrecht GF; Kinniburgh DW; MacDonald AM; Martin JW; Dewey D; APrON Study Team · Journal of developmental origins of health and disease · 2023
    Cohort study309 participantsMental Focus forCholine
  16. Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies.
    Obeid R; Derbyshire E; Schön C · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis30 studies pooledMental Focus forCholine
  17. Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
    Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
    Cohort study125,594 participantsCognitive Support forCholine
  18. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support forCholine
  19. Association of trimethylamine oxide and its precursors with cognitive impairment: a systematic review and meta-analysis.
    Long C; Li Z; Feng H; Jiang Y; Pu Y; Tao J; Yue R · Frontiers in aging neuroscience · 2024
    Meta-analysis82,246 participants9 studies pooledCognitive Support forCholine
  20. Gut microbiota-mediated choline metabolism exacerbates cognitive impairment induced by chronic cerebral hypoperfusion.
    Li X; Ren Y; Gao X; Wang H; Zhang J; Xie J; Liang J; Zhao B; Zhou H; Yin J · Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Cross-sectional studyCognitive Support forCholine
  21. Randomized, double-blind, placebo-controlled clinical trial of choline supplementation in school-aged children with fetal alcohol spectrum disorders.
    Nguyen TT; Risbud RD; Mattson SN; Chambers CD; Thomas JD · The American journal of clinical nutrition · 2017
    Randomized trial55 participantsCognitive Support forCholine
  22. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsCognitive Support forCholine
  23. Choline intake during pregnancy and child cognition at age 7 years.
    Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
    Cohort study895 participantsCognitive Support forCholine
  24. Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
    Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
    Randomized trial52 participantsCognitive Support forCholine
  25. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  26. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  27. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  28. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  29. Synergistic effects of creatine, carbs, protein on repeated sprint performance.
    Wang Y; Wei H; Cheng X; Chen Z · Scientific reports · 2026
    Randomized trial60 participantsEnergy forCreatine
  30. The Effects of Creatine Monohydrate Supplementation on Recovery from Eccentric Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial Considering Sex and Age Differences.
    Yamaguchi S; Inami T; Nishioka T; Morito A; Ishiyama K; Murayama M · Nutrients · 2025
    Randomized trial40 participantsEnergy forCreatine
  31. The Effect of Prior Creatine Intake for 28 Days on Accelerated Recovery from Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial.
    Yamaguchi S; Inami T; Ishida H; Morito A; Yamada S; Nagata N; Murayama M · Nutrients · 2024
    Randomized trial20 participantsEnergy forCreatine
  32. Creatine supplementation attenuates the rate of fatigue development during intermittent isometric exercise performed above end-test torque.
    Abdalla LHP; Broxterman RM; Greco CC; Denadai BS · Experimental physiology · 2021
    Randomized trial16 participantsEnergy forCreatine
  33. The effect of continuous low dose creatine supplementation on force, power, and total work.
    Burke DG; Silver S; Holt LE; Smith Palmer T; Culligan CJ; Chilibeck PD · International journal of sport nutrition and exercise metabolism · 2000
    Randomized trial41 participantsEnergy forCreatine
  34. Sleep symptoms associated with intake of specific dietary nutrients.
    Grandner MA; Jackson N; Gerstner JR; Knutson KL · Journal of sleep research · 2014
    Cross-sectional study4,552 participantsEnergy forTheobromine
  35. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  36. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  37. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  38. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  39. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  40. Creatine in combination with resistance training and improvement in muscle strength: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusFitness forCreatine
  41. Effect of creatine and weight training on muscle creatine and performance in vegetarians.
    Burke DG; Chilibeck PD; Parise G; Candow DG; Mahoney D; Tarnopolsky M · Medicine and science in sports and exercise · 2004
    Randomized trial42 participantsFitness forCreatine
  42. Long-term creatine intake is beneficial to muscle performance during resistance training.
    Vandenberghe K; Goris M; Van Hecke P; Van Leemputte M; Vangerven L; Hespel P · Journal of applied physiology (Bethesda, Md. : 1985) · 1998
    Randomized trial19 participantsFitness forCreatine
  43. Effects of Combined Versus Single Supplementation of Creatine, Beta-Alanine, and L-Citrulline During Short Sprint Interval Training on Basketball Players' Performance: A Double-Blind Randomized Placebo-Controlled Trial.
    Li M; Sheykhlouvand M · International journal of sports physiology and performance · 2025
    Randomized trial48 participantsFitness forCreatine
  44. The Additive Effects of Creatine Supplementation and Exercise Training in an Aging Population: A Systematic Review of Randomized Controlled Trials.
    Stares A; Bains M · Journal of geriatric physical therapy (2001) · 2021
    Systematic review17 studies pooledFitness forCreatine
  45. Additive effects of beta-alanine and sodium bicarbonate on upper-body intermittent performance.
    Tobias G; Benatti FB; de Salles Painelli V; Roschel H; Gualano B; Sale C; Harris RC; Lancha AH; Artioli GG · Amino acids · 2013
    Randomized trial37 participantsFitness forSodium
  46. Sodium bicarbonate supplementation improves severe-intensity intermittent exercise under moderate acute hypoxic conditions.
    Deb SK; Gough LA; Sparks SA; McNaughton LR · European journal of applied physiology · 2018
    Randomized trial11 participantsFitness forSodium
  47. The effects of sodium bicarbonate ingestion on swimming interval performance in trained competitive swimmers.
    Gough LA; Newbury JW; Price M · European journal of applied physiology · 2023
    Randomized trial14 participantsFitness forSodium
  48. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  49. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  50. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  51. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  52. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  53. Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.
    Wozniak JR; Fink BA; Fuglestad AJ; Eckerle JK; Boys CJ; Sandness KE; Radke JP; Miller NC; Lindgren C; Brearley AM; Zeisel SH; Georgieff MK · Journal of neurodevelopmental disorders · 2021
    Randomized trial31 participantsMental Focus forCholine
  54. Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
    Akison LK; Kuo J; Reid N; Boyd RN; Moritz KM · Alcoholism, clinical and experimental research · 2019
    Systematic reviewMental Focus forCholine
  55. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
    Ross RG; Hunter SK; McCarthy L; Beuler J; Hutchison AK; Wagner BD; Leonard S; Stevens KE; Freedman R · The American journal of psychiatry · 2013
    Randomized trialMental Focus forCholine
  56. A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
    Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
    Randomized trial60 participantsMetabolism Boost forCaffeine
  57. Oolong tea increases metabolic rate and fat oxidation in men.
    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
  58. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
  59. Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  60. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  61. Creatine target engagement with brain bioenergetics: a dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression.
    Kondo DG; Forrest LN; Shi X; Sung YH; Hellem TL; Huber RS; Renshaw PF · Amino acids · 2017
    Randomized trialMetabolism Boost forCreatine
  62. Creatine supplementation and glycemic control: a systematic review.
    Pinto CL; Botelho PB; Pimentel GD; Campos-Ferraz PL; Mota JF · Amino acids · 2017
    Systematic reviewMetabolism Boost forCreatine
  63. The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure.
    Andrews R; Greenhaff P; Curtis S; Perry A; Cowley AJ · European heart journal · 1998
    Clinical trialMetabolism Boost forCreatine
  64. A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
    Rowland A; Edwards S; Prieto-Bellver G; Menz B; Rowland A; Cornelisse E; Karapetis CS; Wallen MP; Hopkins AM · Journal of the International Society of Sports Nutrition · 2026
    Narrative reviewMetabolism Boost forCreatine
  65. Creatine Supplementation Beyond Athletics: Benefits of Different Types of Creatine for Women, Vegans, and Clinical Populations-A Narrative Review.
    Gutiérrez-Hellín J; Del Coso J; Franco-Andrés A; Gamonales JM; Espada MC; González-García J; López-Moreno M; Varillas-Delgado D · Nutrients · 2025
    Narrative reviewMetabolism Boost forCreatine
  66. Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.
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