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Wonder-C Orange Tangerine

Codeage Nanofood
4.7
★ ★ ★ ★ ★
(1364 ratings)
Vitamin C 1000 mg
Vitamin E 10 IU
Rose Hip 50 mg
Product Image
Score60
Broad nutrient coverage and a liquid format are useful, but opaque liposomal details and upper-level vitamin D dosing require care.
How scoring works
Quantity:16 Fluid Ounce(s) • (30 servings)
Goals:
Immunity
General Health
Skin Health
Anti-Inflammatory Support
Vision Support

Score 60

Broad nutrient coverage and a liquid format are useful, but opaque liposomal details and upper-level vitamin D dosing require care.
How scoring works
$29.99($0.99 per serving)
Pure Formulas
$ 29.99
iHerb
$ 29.99
BodyBuilding.com
$ 29.99
Vitacost
$ 29.99
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Analysis

The liquid supplies 1,000 mg of vitamin C with vitamin D3, natural vitamin E, zinc bisglycinate, quercetin, rose hip, and echinacea. The fat-containing matrix may help with absorption of the fat-soluble vitamins, and the nutrient mix covers several antioxidant pathways.

A 4,000 mg liposomal proprietary blend dominates the formula without identifying its individual components or amounts. Vitamin D3 reaches 100 mcg, while vitamin E and the botanicals are comparatively modest and the serving also adds carbohydrate and fat.

The flavored liquid may appeal to people who dislike pills, but it offers limited value and less dose clarity than simpler vitamin C products. It fits best when the broader nutrient mix is wanted and total vitamin D intake is tracked carefully.

Who is it for
  • Adults who prefer liquid supplements
  • People seeking combined vitamin C, D, E, and zinc
  • Users able to monitor total vitamin D intake
Best for
  • Broad immune-related nutrient coverage
  • Pill-free use
  • Vitamin C with fat-soluble nutrients

Pros

  • Provides 1,000 mg of vitamin C
  • Uses vitamin D3 and natural vitamin E
  • Includes zinc bisglycinate
  • Liquid format may suit people who dislike capsules

Cons

  • Liposomal blend components are not disclosed
  • Adds notable carbohydrate and fat per serving
  • Serving value is limited
  • Vitamin E and botanical amounts are modest

Warnings

  • The 100 mcg vitamin D3 amount reaches the adult daily upper intake level, so count other vitamin D sources
  • Echinacea may be unsuitable for people using immunosuppressant medicines
  • The 1,000 mg vitamin C amount may cause digestive upset

Nutrient quality

74 High impact

Zinc bisglycinate and natural vitamin E are useful forms, and the core nutrients have meaningful amounts. High vitamin D and an undisclosed liposomal blend create dose and formulation uncertainty.

.

Ingredient transparency

49 Lower impact

Most named nutrients have clear amounts, but the large liposomal blend does not disclose its constituents. Usage directions, non-active ingredients, and details behind the delivery system are incomplete.

.

Customer satisfaction

71 High impact

The listed average rating is strong and supported by a large review count. Specific feedback is not supplied to evaluate recurring tolerance, taste, or purpose-related experiences.

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Value for money

49 Lower impact

Relevant nutrient forms add quality, but the key liposomal blend cannot be fully assessed. The comparatively costly serving and hidden formulation details weaken its category competitiveness.

.
Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A Goal FitB Strength of SupportB+ CoverageB Formula Quality
Vitamin C · 1000 mgZinc · 15 mgVitamin D · 100 mcg

Vitamin C, vitamin D3, zinc, and vitamin E provide broad antioxidant and immune-related support. A fat-containing liquid matrix may aid absorption of the fat-soluble vitamins.

Vitamin D is supplied at a high amount, while vitamin E and several botanicals are comparatively light. The proprietary liposomal blend does not reveal its components, and people using other vitamin D sources should account for total intake.

Study evidence
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
General Health
General Health
Impact
High effect
A- Goal FitB Strength of SupportB- CoverageC Formula Quality
Vitamin D · 100 mcgZinc · 15 mgVitamin C · 1000 mg

Vitamin C, zinc bisglycinate, vitamin D3, and vitamin E provide credible antioxidant and immune support. Dietary fat may also aid vitamin D absorption.

The vitamin D3 amount reaches the adult daily upper intake level, so other vitamin D sources should be counted carefully. Echinacea may conflict with immunosuppressant treatment, while the large proprietary liposomal blend prevents full dose assessment.

Study evidence
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Skin Health
Skin Health
Impact
High effect
B Goal FitB Strength of SupportB- CoverageC Formula Quality
Zinc · 15 mgVitamin C · 1000 mgVitamin E · 10 IU

Vitamin C, natural vitamin E, and zinc provide useful antioxidant and collagen-cofactor support. The formula lacks collagen, ceramides, or hyaluronic acid, so its skin benefits remain mostly supportive.

The large liposomal blend does not disclose how much of each ingredient it carries, which limits confidence in delivery claims. Vitamin D is supplied at the adult daily upper limit, so long-term use alongside other vitamin D sources may raise the risk of excessive calcium levels.

Study evidence
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitC+ Strength of SupportB CoverageC Formula Quality
Vitamin D · 100 mcgVitamin E · 10 IUVitamin C · 1000 mg

Vitamin C, vitamin D, vitamin E, zinc, and quercetin provide broad antioxidant and immune-regulating support. Quercetin is modest, while the large proprietary liposomal blend prevents confirmation of delivery components and their amounts.

The formula covers several useful pathways but relies more on general immune nutrition than direct anti-inflammatory actives. Vitamin D is supplied at the common adult upper daily intake, so stacking it with other high-dose vitamin D products may increase the risk of excessive calcium.

Study evidence
Vitamin C Supportive 50 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Vision Support
Vision Support
Impact
High effect
C+ Goal FitB- Strength of SupportC CoverageC- Formula Quality
Zinc · 15 mgVitamin E · 10 IUVitamin C · 1000 mg

Vitamin C, natural vitamin E, zinc, and vitamin D3 provide several antioxidant and retinal-support nutrients. The vitamin C and zinc amounts are meaningful, while vitamin E is modest and no macular carotenoids or DHA are included.

The liposomal blend may support delivery but does not disclose its individual components, and immune botanicals add little eye-specific value. The 100 mcg vitamin D3 amount reaches the adult upper intake level, so combining it with other high-dose vitamin D products may create excessive intake.

Study evidence
Vitamin C Disputed 24 studies
Vitamin D Disputed 35 studies
Vitamin E Disputed 35 studies
Zinc Supportive 39 studies

Ingredients

IngredientAmount per serving
Calories
68 Calorie(s)
Total Fat
4 Gram(s)
Total Carbohydrates
8 Gram(s)
Vitamin C (Ascorbic Acid)
 1000 mg
Vitamin D (Cholecalciferol)
 100 mcg
Vitamin E (D-Alpha-Tocopherol)
 10 IU
Zinc (Zinc Bisglycinate)
 15 mg
Liposomal Proprietary Blend
4000 mg
Rose Hip
50 mg
Quercetin
50 mg
Echinacea
50 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Vitamin C (Ascorbic Acid) · 1000 mg OverallScore73
B Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD- Value

The 1,000 mg dose is paired with a liposomal blend that may support absorption beyond ordinary ascorbic acid. The proprietary lipid blend does not disclose its composition, and the liquid also contains notable carbohydrate and fat. Value is limited compared with other premium delivery options.

View ingredientView products
Vitamin E (D-Alpha-Tocopherol) · 10 IU OverallScore44
D Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyD- Value

Natural d-alpha-tocopherol is clearly identified, but the amount is below the adult minimum used here. The formula offers neither mixed tocopherols nor tocotrienols. A high serving cost further limits its fit as a vitamin E option.

View ingredientView products
Loading alternative details
83 Performance

Vitamin E Complete

OL Olympian Labs
Natural d-alpha-tocopherol and mixed tocotrienols provide clearer and broader vitamin E-family coverage than the original proprietary blend. It is a focused vitamin E alternative rather than a replacement for vitamin C, vitamin D, and zinc.
82 Performance

Meta-C 1000 mg Tablets

NutriBiotic Immunity
A named vitamin C complex with calcium and metabolites offers clearer active disclosure and a potentially gentler format. Spirulina adds limited clarity, and the formula does not include vitamin D, vitamin E, or zinc.
82 Performance

Liposomal Vitamin C 1000 mg

SunLipid
Buffered vitamin C, phospholipids, and MCT create a more clearly defined liposomal delivery system than the original hidden blend. Sodium may matter on a strict limit, and the narrower product omits vitamin D, vitamin E, and zinc.
86 Budget

C

Swanson
Fully buffered calcium ascorbate provides focused vitamin C support with much better value and likely gentler digestion. The narrower formula omits vitamin D, vitamin E, and zinc, so it suits users who mainly want vitamin C.
84 Budget

Mixed Vitamin E 400 IU

Natural Factors
Natural vitamin E with mixed tocopherols offers broader vitamin E-family coverage at a lower serving cost. It does not replace vitamin C, vitamin D, or zinc, and the substantial vitamin E amount warrants care with anticoagulant or antiplatelet medicines.
88 Budget

Sodium Ascorbate

NutriBiotic Immunity
Buffered sodium ascorbate supplies vitamin C with exceptional economy and no hidden liposomal blend. Careful measuring and sodium accounting are important, while the other nutrients in the original formula are absent.
84 Value

Natural E-400

NOW
Natural d-alpha-tocopheryl acetate provides simple, clearly identified vitamin E at much better value. The alpha-only profile lacks mixed tocopherols, and the substantial dose may add bleeding risk with anticoagulant or antiplatelet medicines.
86 Value

Ester-C Plus 1000 mg Vitamin C

Solgar
Buffered vitamin C with citrus bioflavonoids provides a focused formula with good stomach-comfort potential and sound value. It lacks the original vitamin D, vitamin E, and zinc, but avoids a hidden liposomal blend.
81 Value

Natural E-400

Protocol For Life Balance
Natural vitamin E with mixed tocopherols and selenium offers a transparent antioxidant formula with reasonable value. The vitamin E amount is high for routine use, and the product does not cover the original vitamin C, vitamin D, or zinc roles.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  2. Vitamin C for the management of COVID-19: a systematic review and meta-analysis of randomized controlled trials.
    Abid H; Mushtaq I; Munir ABI; Shakil J; Vinjamuri S; Tadasare N; Kiran F; Muhammad Wali Mirza A; Fatima Khidri F; Shahid A; Ayyan M; Ehsan M; Cheema HA; Alsubari AMA; Sahra S; Siddiqi NI · Annals of medicine and surgery (2012) · 2026
    Meta-analysis9 studies pooledImmunity forVitamin C
  3. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  4. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
    Meydani SN; Barklund MP; Liu S; Meydani M; Miller RA; Cannon JG; Morrow FD; Rocklin R; Blumberg JB · The American journal of clinical nutrition · 1990
    Randomized trial32 participantsImmunity forVitamin E
  5. Effect of daily vitamin E and multivitamin-mineral supplementation on acute respiratory tract infections in elderly persons: a randomized controlled trial.
    Graat JM; Schouten EG; Kok FJ · JAMA · 2002
    Randomized trial652 participantsImmunity forVitamin E
  6. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  7. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  8. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  9. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  10. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  11. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  12. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  13. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  14. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  15. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  16. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  17. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  18. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  19. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  20. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  21. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  22. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  23. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  24. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  25. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  26. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  27. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  28. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  29. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  30. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  31. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  32. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  33. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  34. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  35. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  36. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  37. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  38. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  39. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  40. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  41. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  42. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  43. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  44. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  45. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  46. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  47. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  48. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  49. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  50. Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
    Chen S; Ahmad B; Palanisamy UD; Hafid SRA; Selvaduray KR; Radhakrishnan AK · Nutrition research (New York, N.Y.) · 2026
    Randomized trial150 participantsImmunity forVitamin E
  51. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers.
    Mahalingam D; Radhakrishnan AK; Amom Z; Ibrahim N; Nesaretnam K · European journal of clinical nutrition · 2011
    Randomized trialImmunity forVitamin E
  52. Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.
    Hemilä H; Virtamo J; Albanes D; Kaprio J · Chest · 2004
    Randomized trial29,133 participantsImmunity forVitamin E
  53. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
    Meydani SN; Meydani M; Blumberg JB; Leka LS; Siber G; Loszewski R; Thompson C; Pedrosa MC; Diamond RD; Stollar BD · JAMA · 1997
    Randomized trial88 participantsImmunity forVitamin E
  54. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  55. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  56. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  57. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  58. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  59. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  60. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  61. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  62. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  63. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  64. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  65. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  66. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forVitamin E Skin Health forZinc
  67. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  68. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  69. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  70. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  71. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  72. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  73. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  74. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  75. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  76. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C Vision Support forVitamin E
  77. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C
  78. Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration.
    Merle BMJ; Silver RE; Rosner B; Seddon JM · Investigative ophthalmology & visual science · 2017
    Cohort study2,146 participantsVision Support forVitamin D
  79. Circulating vitamin D concentration and age-related macular degeneration: Systematic review and meta-analysis.
    Annweiler C; Drouet M; Duval GT; Paré PY; Leruez S; Dinomais M; Milea D · Maturitas · 2017
    Meta-analysis11 studies pooledVision Support forVitamin D
  80. Low serum vitamin D is associated with axial length and risk of myopia in young children.
    Tideman JW; Polling JR; Voortman T; Jaddoe VW; Uitterlinden AG; Hofman A; Vingerling JR; Franco OH; Klaver CC · European journal of epidemiology · 2017
    Cohort study2,666 participantsVision Support forVitamin D
  81. The effect of vitamin D supplementation on the outcome of treatment with bevacizumab in diabetic macular edema: a randomized clinical trial.
    Fekri S; Soheilian M; Roozdar S; Abtahi SH; Nouri H · International ophthalmology · 2022
    Randomized trial83 participantsVision Support forVitamin D
  82. Vitamin D Deficiency and Dry Eye Disease: A Retrospective Cohort Study.
    Shmushkevich SB; Bajrami S; Beauchamp B; Kane JS; Mutawe DL; Hollinger JC; Marks VA; Parekh PK; Rothman AL; Ansari ZA; Williams BK; Galor A · American journal of ophthalmology · 2026
    Cohort study12,095,004 participantsVision Support forVitamin D
  83. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin E
  84. Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
    Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
    Cohort study35,551 participantsVision Support forVitamin E
  85. Long-term nutrient intake and 5-year change in nuclear lens opacities.
    Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
    Cohort study408 participantsVision Support forVitamin E
  86. Dietary intake of antioxidants and risk of age-related macular degeneration.
    van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
    Cohort study4,765 participantsVision Support forVitamin E
  87. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  88. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  89. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  90. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  91. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc