Product Image

Hairfluence

ZHOU
4.2
★ ★ ★ ★ ★
(19797 ratings)
Biotin 5000 mcg
Vitamin B5 100 mg
Calcium 215 mg
Collagen 400 mg
Hydrolyzed keratin 50 mg
Product Image
Score71
Broad hair and nail coverage is appealing, but underdosed structural actives, confusing duplicate entries, and high biotin and vitamin A are meaningful drawbacks.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Nail Health
Hair Health
Skin Health

Score 71

Broad hair and nail coverage is appealing, but underdosed structural actives, confusing duplicate entries, and high biotin and vitamin A are meaningful drawbacks.
How scoring works
$24.79($0.82 per serving)
Pure Formulas
$ 24.79
iHerb
$ 24.79
Amazon
$ 24.79
Walmart
$ 24.79
Daily Vita
$ 28.32
Report prices

Analysis

Biotin, MSM, vitamin C, methylcobalamin, collagen, and keratin create broad beauty-nutrient coverage. Bamboo extract adds a silicon source, while the two-capsule serving keeps the formula manageable.

Collagen hydrolysate and MSM are only 400 mg each, and keratin is just 50 mg, limiting structural depth. Duplicate thiamine and riboflavin entries make totals harder to interpret, and several forms remain unspecified.

The formula offers breadth but weaker value than more focused collagen or keratin products. High biotin can distort laboratory results, and the preformed vitamin A amount requires extra caution during pregnancy.

Who is it for
  • Adults seeking broad capsule-based beauty nutrition
  • People who want biotin, MSM, collagen, and keratin together
Best for
  • Broad hair and nail nutrient coverage
  • Biotin and MSM supplementation

Pros

  • Combines biotin, MSM, collagen, and keratin
  • Uses methylcobalamin
  • Provides full active amounts rather than one total blend

Cons

  • Collagen and keratin are lightly dosed
  • Duplicate nutrient entries complicate interpretation
  • Value is weak for the structural amounts

Warnings

  • The 5,000 mcg biotin amount can interfere with thyroid, cardiac, and other laboratory tests, so disclose use before testing
  • The 1,800 mcg preformed vitamin A amount may be unsuitable during pregnancy or pregnancy planning without professional guidance

Nutrient quality

70 High impact

Vitamin D3 and methylcobalamin are useful, while several B vitamins use conventional forms. MSM and collagen are modest, with keratin and bamboo extract supplied in smaller amounts.

Ingredient transparency

80 Highest impact

Every listed active has a specific amount. Inactive ingredients are not supplied.

Customer satisfaction

65 High impact

The supplied average indicates mixed aggregate satisfaction. No detailed experience reports are available to identify repeated complaints or confirm perceived benefits.

Value for money

64 Moderate impact

The broad ingredient list supports some value, but key structural doses are modest. Serving value appears moderate rather than favorable.

Report analysis

Goals

Nail Health
Impact
Highest effect
A Goal FitB Strength of SupportB+ CoverageB+ Formula Quality
Collagen · 400 mgBiotin · 5000 mcg

Biotin provides the strongest part of the formula, while hydrolyzed collagen, keratin, MSM, vitamin C, and B vitamins address several complementary nail pathways. The combination is logically aimed at keratin production and structural support.

The collagen and keratin amounts are small compared with structural-protein servings, so biotin carries most of the expected benefit. Exact quantities and hydrolyzed forms improve clarity, while high-dose biotin should be disclosed before blood testing because it can distort some results.

Study evidence
Biotin Supportive 8 studies
Collagen Supportive 4 studies
Vitamin C Supportive 1 study
Hair Health
Impact
High effect
B Goal FitC Strength of SupportB- CoverageC+ Formula Quality
Biotin · 5000 mcgVitamin D · 2.5 mcgVitamin C · 100 mgCollagen · 400 mg

Biotin, collagen, keratin, MSM, vitamin C, and several micronutrients cover structural and nutritional aspects of hair health. Evidence is strongest for correcting deficiencies, while the small collagen and keratin amounts limit expected structural support.

The formula discloses each active, but several duplicate nutrient entries and modest specialty doses make it less efficient. The high biotin amount can interfere with thyroid, cardiac, and other laboratory tests.

Study evidence
Biotin Supportive 4 studies
Collagen Supportive 3 studies
Vitamin C Mixed 5 studies
Skin Health
Impact
High effect
B Goal FitD+ Strength of SupportC CoverageC+ Formula Quality
Vitamin C · 100 mgCollagen · 400 mg

Collagen hydrolysate, keratin, MSM, vitamin C, and vitamin A create a skin-directed structure and antioxidant framework. The collagen amount is far below typical collagen-focused servings, and keratin is also modest.

High biotin adds little unless deficiency is present and can interfere with laboratory tests. The preformed vitamin A amount may be unsuitable during pregnancy, while the long B-vitamin list adds bulk without fixing the weak structural doses.

Study evidence
Biotin Supportive 10 studies
Collagen Supportive 62 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies

Ingredients

IngredientAmount per serving
Vitamin A (Retinyl Palmitate)
1800 mcg
Vitamin C (Ascorbic Acid)
100 mg
Vitamin D3 (Cholecalciferol)
2.5 mcg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
5 mg
Riboflavin (Vitamin B2)
5 mg
Niacin
5 mg
Vitamin B6 (Pyridoxine Hydrochloride)
5 mg
Folate
340 mcg DFE
Vitamin B12 (Methylcobalamin)
20 mcg
Biotin
5000 mcg
Pantothenic Acid (Calcium D-Pantothenate)
100 mg
Calcium (Calcium Carbonate)
215 mg
MSM
400 mg
Collagen Hydrolysate
400 mg
Bamboo Stem Extract
20 mg
hydrolyzed Keratin
50 mg
Adults 18–50
Report overview
Biotin · 5000 mcg OverallScore85
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

The 5,000 mcg dose reaches the high-potency range, although the label does not verify the active d-biotin isomer. The vegetable capsule format is practical, and the broad formula makes a biotin-only cost comparison incomplete. Because 5,000 mcg of biotin can interfere with some lab tests, tell the testing clinician before blood work.

B Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

D-calcium pantothenate is a well-absorbed form, and the 100 mg dose supports general use. The source and active amount are clear, but the missing Other Ingredients list leaves additive quality uncertain. The cost per target B5 amount is high, while 5,000 mcg of biotin can interfere with some laboratory tests and 1,800 mcg of preformed vitamin A may be unsuitable during pregnancy.

C+ Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

A modest calcium amount is clearly supplied as calcium carbonate. The dose is efficiently sized, but carbonate is less absorbable and calcium is secondary to the hair-support formula. High serving cost makes it a poor choice for focused calcium value.

Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  2. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health Skin Health forBiotin
  3. Low-Molecular-Weight Collagen Peptide Supplementation Improves Cellulite Severity, Skin Elasticity, and Hair Shaft Diameter: A Clinical Study with Pharmacokinetic Evaluation.
    Hwang S; Won J; Kim S; Kang W; Park M · Journal of medicinal food · 2026
    Randomized trial114 participantsHair Health forCollagen
  4. Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing.
    Biełach-Bazyluk A; Jurga M; Flisiak I; Zbroch E · Nutrients · 2026
    Narrative reviewHair Health forCollagen
  5. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health Skin Health forBiotin
  6. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  7. Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women-A Randomized Controlled Study.
    Duangjai A; Srivilai J; Nangola S; Amornlerdpison D · Clinics and practice · 2025
    Randomized trialHair Health forCollagen
  8. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  9. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  10. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  11. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  12. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  13. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  14. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  15. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  16. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin
  17. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
    Hexsel D; Zague V; Schunck M; Siega C; Camozzato FO; Oesser S · Journal of cosmetic dermatology · 2018
    Single-arm trial25 participantsNail Health forCollagen
  18. Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial.
    Vleminckx S; Virgilio N; Asserin J; Prawitt J; Silva CIF · Journal of cosmetic dermatology · 2024
    Randomized trial85 participantsNail Health forCollagen
  19. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forCollagen
  20. Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.
    Kern JS; Kohlhase J; Bruckner-Tuderman L; Has C · The Journal of investigative dermatology · 2006
    Observational study41 participantsNail Health forCollagen
  21. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  22. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  23. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  24. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin
  25. Exploring the Impact of Hydrolyzed Collagen Oral Supplementation on Skin Rejuvenation: A Systematic Review and Meta-Analysis.
    Dewi DAR; Arimuko A; Norawati L; Yenny SW; Setiasih NL; Perdiyana A; Arkania N; Nadhira F; Wiliantari N · Cureus · 2024
    Meta-analysis967 participants14 studies pooledSkin Health forCollagen
  26. Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
    Danessa G; Notario D; Regina R · Indian journal of dermatology, venereology and leprology · 2025
    Meta-analysis646 participants10 studies pooledSkin Health forCollagen
  27. Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study.
    Lee M; Kim E; Ahn H; Son S; Lee H · Food & function · 2023
    Randomized trial100 participantsSkin Health forCollagen
  28. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study.
    Kim DU; Chung HC; Choi J; Sakai Y; Lee BY · Nutrients · 2018
    Randomized trial64 participantsSkin Health forCollagen
  29. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis.
    de Miranda RB; Weimer P; Rossi RC · International journal of dermatology · 2021
    Meta-analysis1,125 participants19 studies pooledSkin Health forCollagen
  30. Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis.
    Farris P; Berson D; Bhatia N; Goldberg D; Lain E; Mariwalla K; Zeichner J; Miller D; McGuire T; Kizoulis M · Journal of drugs in dermatology : JDD · 2024
    Meta-analysis471 participants6 studies pooledSkin Health forVitamin A
  31. Tensile properties and contours of aging facial skin. A controlled double-blind comparative study of the effects of retinol, melibiose-lactose and their association.
    Piérard-Franchimont C; Castelli D; Cromphaut IV; Bertin C; Ries G; Cauwenbergh G; Piérard GE · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
    Randomized trial120 participantsSkin Health forVitamin A
  32. Antiaging action of retinol: from molecular to clinical.
    Bellemère G; Stamatas GN; Bruère V; Bertin C; Issachar N; Oddos T · Skin pharmacology and physiology · 2009
    Randomized trial48 participantsSkin Health forVitamin A
  33. An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.
    Balado-Simó P; Morgado-Carrasco D; Gómez-Armayones S; López-Ferrer A; Barco D; Ferrándiz-Pulido C; Podlipnik S · Journal of clinical medicine · 2025
    Narrative reviewSkin Health forVitamin A
  34. Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial.
    Chang H; Tao K; Yang Y; Wang Y; Ge M; Wang X; Tang S; Yu H · Journal of cosmetic dermatology · 2025
    Randomized trialSkin Health forVitamin A
  35. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  36. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  37. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  38. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  39. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C