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Liposomal Vitamin C 1000 mg

4.8
★ ★ ★ ★ ★
(30045 ratings)
Vitamin C 1000 mg
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Score73

A larger-supply lipid-based vitamin C capsule with a strong active amount. Delivery transparency remains the central weakness despite improved practical value.

How scoring works
Capsule
Quantity:180 Capsule(s) • (90 servings)
Goals:
General Health
Immunity
Skin Health
Anti-Inflammatory Support
Vision Support

Score 73

A larger-supply lipid-based vitamin C capsule with a strong active amount. Delivery transparency remains the central weakness despite improved practical value.

How scoring works

Also available as

1 option
60 servings C 1000 mg • 60 Capsule(s) • 30 servings $17.97 ($0.59 per serving)
$43.99($0.48 per serving)
Vitacost
$ 46.25
iHerb
$ 43.99
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Analysis

The two-capsule serving provides 1,000 mg of vitamin C for immune, antioxidant, and collagen support. One gram of fat aligns with the stated lipid-based delivery approach.

No phospholipid source, carrier composition, or liposome specification is included in the supplied data. Any absorption or stomach-comfort advantage therefore remains uncertain.

The larger bottle offers better routine practicality than the smaller version. Its focused role is clear, but it does not cover broader vision, skin-hydration, or inflammatory pathways.

Who is it for
  • Regular users seeking lipid-based vitamin C
  • Adults comfortable taking two capsules
  • People prioritizing a larger supply
Best for
  • Routine high-dose vitamin C
  • Immune support
  • Antioxidant and collagen support

Pros

  • Clearly stated 1,000 mg amount
  • Includes a lipid component
  • Larger serving supply
  • Convenient capsule delivery

Cons

  • Carrier composition is not disclosed
  • Liposome quality cannot be verified
  • Two capsules are needed per serving
  • Narrow pathway coverage

Warnings

  • A 1,000 mg serving may cause nausea or diarrhea
  • People prone to calcium-oxalate kidney stones should discuss regular high-dose use with a clinician
  • The supplied label does not establish the quality of the liposomal system

Nutrient quality

88 Highest impact

A meaningful vitamin C amount and claimed lipid delivery fit the intended use. Missing carrier details prevent full verification of the absorption advantage.

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Ingredient transparency

61 Moderate impact

The vitamin C amount and basic serving count are disclosed. Missing lipid-carrier details, daily directions, and a complete excipient panel limit verification.

.

Customer satisfaction

73 High impact

The aggregate rating is strong and supported by large feedback volume. Complaint-level experiences are unavailable, so repeated drawbacks and purpose fit remain uncertain.

.

Value for money

72 High impact

The serving cost is acceptable but not especially compelling. Basic delivery or incomplete verification limits justification for the price tier.

.
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Goals

General Health
General Health
Impact
Highest effect
A Goal FitA- Strength of SupportB- CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C provides direct support for antioxidant defenses, immune function, and collagen production. The substantial amount is paired with fat, which is consistent with the stated liposomal delivery.

Lipid delivery may improve tolerance or uptake, but the carrier composition and liposome specifications are not disclosed. The formula remains focused, though it does not address broader foundational nutrient gaps.

Study evidence
Vitamin C Supportive 56 studies
Immunity
Immunity
Impact
Highest effect
A+ Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports immune-cell function, barrier defenses, and antioxidant protection. The substantial serving amount meets the main immune-support target.

A lipid component is present, but the supplied data does not identify phospholipids or other details that verify a liposomal delivery system. The focused formula provides strong depth without broader immune coverage.

Study evidence
Vitamin C Supportive 53 studies
Skin Health
Skin Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC+ CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports collagen synthesis and antioxidant defense in skin. Vitamin C has established human and mechanistic evidence for collagen formation and antioxidant protection.

The clearly disclosed 1,000 mg vitamin C amount provides more than enough collagen-synthesis cofactor for most users. Vitamin C covers collagen synthesis and antioxidant defense but not direct hydration or barrier-lipid support.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
C Goal FitB Strength of SupportD CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C supplies substantial antioxidant support that may help limit oxidative stress associated with inflammation. The 1,000 mg amount is meaningful, but it does not directly inhibit a major inflammatory pathway like curcumin or Boswellia.

The product name claims liposomal delivery, yet the supplied label data does not identify phospholipid content or encapsulation details. The high vitamin C amount may cause nausea or diarrhea, and people prone to calcium-oxalate kidney stones may increase urinary oxalate with regular high intake.

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
High effect
C Goal FitB Strength of SupportD CoverageB Formula Quality
Vitamin C · 1000 mg

Vitamin C provides meaningful antioxidant support for the lens and other ocular tissues. The disclosed amount is substantial enough to contribute rather than merely decorate the label.

Its strongest vision evidence comes from use within broader nutrient combinations. The formula does not supply macular carotenoids, retinal omega-3s, or balanced zinc and copper.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Vitamin C (Ascorbic Acid)
 1000 mg
Adults 18–50
Report overview
Vitamin C (Ascorbic Acid) · 1000 mg OverallScore81
B Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyB+ Value

The 1,000 mg serving is well targeted and liposomal delivery may improve uptake and retention. The ingredient data identify ascorbic acid but do not disclose the lipid carrier composition or buffering, which limits verification. Its larger supply provides favorable value for a premium delivery format.

View ingredientView products
Loading alternative details
82 Performance

Liposomal Vitamin C 1000 mg

SunLipid
Ingredient and delivery quality improve with 1,000 mg of vitamin C as sodium ascorbate with a 1,000 mg phospholipid complex and 500 mg of MCTs. Compared with the original 1000 mg liposomal formula, the explicitly disclosed delivery matrix provides clearer liposomal support than a basic vitamin C formula, although the disclosed sodium contribution may matter on a sodium-restricted diet.
86 Performance

Ester-C Plus 1000 mg Vitamin C

Solgar
Ingredient and delivery quality improve with 1,000 mg of buffered Ester-C with 108 mg of calcium and 200 mg of citrus bioflavonoids. Compared with the original 1000 mg liposomal formula, the substantial buffered dose and compatible bioflavonoids broaden support beyond plain ascorbic acid, although complete excipient details are not supplied.
86 Performance

C

Swanson
Ingredient and delivery quality improve with 1,000 mg of calcium ascorbate with 120 mg of calcium and 200 mg of citrus bioflavonoids. Compared with the original 1000 mg liposomal formula, the buffered form and meaningful bioflavonoid amount offer a broader formula than plain ascorbic acid, although complete excipient details are not supplied.
89 Budget

Pure Buffered Calcium Ascorbate

NOW
A lower serving cost comes with 890 mg of vitamin C as buffered calcium ascorbate with 100 mg of calcium, compared with the original 1000 mg liposomal formula. the mineral-bound form may be gentler than plain ascorbic acid and keeps the active formula focused, although the full inactive-ingredient panel is not supplied.
88 Budget

Buffered Gold C

California Gold Nutrition
A lower serving cost comes with 1,000 mg of vitamin C as sodium ascorbate with 130 mg of sodium, compared with the original 1000 mg liposomal formula. the simple buffered formula provides a full amount with no unrelated active ingredients, although the sodium contribution needs consideration on a restricted diet.
88 Budget

Sodium Ascorbate

NutriBiotic Immunity
A lower serving cost comes with 1,100 mg of vitamin C as sodium ascorbate with 120 mg of sodium, compared with the original 1000 mg liposomal formula. the fully buffered powder provides a substantial, clearly disclosed amount, although careful measuring and sodium accounting remain important.
87 Value

Pure Buffered Magnesium Ascorbate

NOW
A stronger quality-to-cost balance comes from 820 mg of vitamin C as magnesium ascorbate with 60 mg of magnesium. Compared with the original 1000 mg liposomal formula, full buffering combines a meaningful vitamin C amount with clear mineral disclosure, while complete use directions and inactive ingredients are not supplied.
84 Value

Ester-C 500 mg With Citrus Bioflavoinds

American Health
A stronger quality-to-cost balance comes from 1,000 mg of buffered Ester-C with a broad citrus bioflavonoid complex. Compared with the original 1000 mg liposomal formula, the formula adds several named citrus compounds while maintaining a substantial vitamin C amount, while the repeated complex entries make the exact internal amounts difficult to interpret.
84 Value

Ester-C 24 Hour Immune Support 1000 mg

NatureSmart
A stronger quality-to-cost balance comes from 1,000 mg of buffered Ester-C with 110 mg of calcium and 102 mg of citrus bioflavonoids. Compared with the original 1000 mg liposomal formula, the buffered form and bioflavonoids combine stomach-comfort potential with a focused vitamin C dose, while the supplied data do not include the complete inactive-ingredient panel.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis.
    Bjelakovic G; Nikolova D; Gluud LL; Simonetti RG; Gluud C · JAMA · 2007
    Meta-analysis232,606 participants68 studies pooledGeneral Health forVitamin C
  2. Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses.
    Xu K; Peng R; Zou Y; Jiang X; Sun Q; Song C · International journal of food sciences and nutrition · 2022
    Meta-analysis76 studies pooledGeneral Health forVitamin C
  3. Vitamin C supplementation in kidney failure: effect on uraemic symptoms.
    Singer RF · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2011
    Randomized trial99 participantsGeneral Health forVitamin C
  4. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  5. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  6. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  7. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  8. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage.
    Fitzpatrick RE; Rostan EF · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2002
    Non-randomized trial10 participantsSkin Health forVitamin C
  9. Vitamin C and postoperative outcomes following mandibular third molar extraction: a randomized split-mouth study.
    Demirel M; Aktas A; Kizil M; Yalcin N · Oral surgery, oral medicine, oral pathology and oral radiology · 2026
    Randomized trial56 participantsSkin Health forVitamin C
  10. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  11. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  12. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  13. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  14. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  15. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  16. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  17. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  18. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  19. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  20. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  21. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  22. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  23. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  24. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  25. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  26. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  27. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  28. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  29. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  30. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  31. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C