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N-Acetyl L-Tyrosine 300 mg

Source Naturals
4.5
★ ★ ★ ★ ★
(569 ratings)
Vitamin B6 25 mg
Folate 400 mcg
Product Image
Score72
A clearly dosed N-acetyl L-tyrosine tablet with folic acid and high B6. Its focused use is clearer than its broad wellness relevance.
How scoring works
Quantity:120 Tablet(s) • (120 servings)
Goals:
General Health

Score 72

A clearly dosed N-acetyl L-tyrosine tablet with folic acid and high B6. Its focused use is clearer than its broad wellness relevance.
How scoring works
$20.03($0.16 per serving)
Vitacost
$ 21.45
Amazon
$ 20.03
iHerb
$ 21.45
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Analysis

The tablet supplies 300 mg N-acetyl L-tyrosine, 400 mcg folic acid, and 25 mg pyridoxine hydrochloride. Tyrosine may support catecholamine synthesis under demanding conditions, but the supplied data do not establish a specific outcome.

The three active amounts are transparent and the formula avoids an opaque blend. Folic acid and pyridoxine are standard forms, and the B6 amount is high relative to routine nutritional needs.

It fits adults specifically seeking N-acetyl L-tyrosine rather than a general B-vitamin or hair product. Users taking thyroid medication, levodopa, or other B6 supplements should review it carefully.

Who is it for
  • Adults specifically seeking N-acetyl L-tyrosine
  • Users wanting a transparent three-ingredient formula
  • People monitoring total B6 intake
Best for
  • Tyrosine precursor support
  • Demand-related focus support
  • Folate and B6 intake

Pros

  • Clearly states all three active amounts
  • Avoids a proprietary blend
  • Provides a focused tyrosine derivative

Cons

  • Vitamin B6 is high for long-term use
  • Uses folic acid rather than methylfolate
  • Narrow relevance to broad nutrition

Warnings

  • Long-term 25 mg vitamin B6 intake can contribute to tingling or neuropathy
  • Tyrosine can interact with levodopa and thyroid medication
  • People with hyperthyroidism should review tyrosine use with a clinician

Nutrient quality

59 Moderate impact

N-acetyl L-tyrosine at 300 mg is modest but usable, while the vitamins are substantial. Vitamin B6 at 25 mg is high for routine long-term supplementation.

Ingredient transparency

80 High impact

Every listed active ingredient has a specific amount. No proprietary blend hides a listed active dose.

Customer satisfaction

67 High impact

The favorable rating is supported by a large review base. No review text is available to assess recurring complaints or firsthand results.

Value for money

81 Highest impact

The simple, fully dosed formula offers fair quality for its cost. A long bottle life provides strong practical value per serving.

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Goals

General Health
General Health
Impact
High effect
B- Goal FitB- Strength of SupportC+ CoverageB+ Formula Quality
Folate · 400 mcg

Folate and vitamin B6 support basic methylation and amino-acid metabolism, while N-acetyl L-tyrosine gives the formula a cognitive-performance focus. The listed amounts are meaningful enough to assess rather than hidden in a blend.

Synthetic folic acid and pyridoxine are less preferred than active vitamin forms. Missing vitamin B12 also makes the folate-centered support less complete for a foundational daily formula.

Study evidence
Folate Supportive 80 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 25 mg
Folate (Folic Acid)
 400 mcg
N-Acetyl L-Tyrosine
300 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
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Vitamin B6 (Pyridoxine Hydrochloride) · 25 mg OverallScore74
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The 25 mg vitamin B6 dose is well targeted and easy to take in one tablet. Pyridoxine hydrochloride is a precursor form, and no riboflavin cofactor is listed to support conversion to active B6. Cost efficiency is good rather than exceptional for this form.

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Folate (Folic Acid) · 400 mcg OverallScore41
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value

Folic acid provides basic folate coverage, but it requires metabolic conversion and is less suitable for people seeking an active folate form. The label does not express the amount as DFE or include vitamin B12, which limits clarity and safety support. The low serving cost helps value, though the formula is centered on N-acetyl L-tyrosine rather than comprehensive folate support.

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82 Performance

BioActive Vitamin B

Terry Naturally
<p>Active P-5-P, methylfolate, and methylcobalamin form a compact B-vitamin combination that is better aligned with general and hair-support goals. The B6 amount may still be high for long-term use, and N-acetyl L-tyrosine is not included.</p>
86 Performance

Methyl B-12 Methyl Folate Lonzenge Natural Cherry Flavor

Solaray
<p>Methylfolate and methylcobalamin provide higher-quality active forms for targeted folate and B12 support. Vitamin B6 and N-acetyl L-tyrosine are absent, so the formula is less suitable when those are the main reasons for use.</p>
86 Performance

B-6 B-12 Folic Acid Drop Ins Natural Mixed Berry Flavor

KAL
<p>Active P-5-P, methylfolate, and methylcobalamin provide broader B-vitamin coverage in a clearly dosed liquid. The concentrated B12 amount suits targeted use more than basic maintenance, and N-acetyl L-tyrosine is omitted.</p>
88 Budget

MegaFolinic 800 mcg

Source Naturals
<p>Active folinic acid offers a much lower-cost and more refined folate option than conventional folic acid. It drops both N-acetyl L-tyrosine and vitamin B6, so it is appropriate only when folate is the priority.</p>
85 Budget

Vitamin B6 25 mg

Solgar
<p>A very inexpensive single-nutrient option preserves the original’s vitamin B6 amount. It uses the same pyridoxine form and omits both folate and N-acetyl L-tyrosine, so hair and general-health coverage becomes narrower.</p>
89 Budget

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
<p>Active P-5-P improves vitamin B6 form quality at a lower serving cost. The dose is higher, while folate and N-acetyl L-tyrosine are absent, so the original’s full purpose is not preserved.</p>
81 Value

Folic Acid B6 & B12

Mason Natural
<p>A low-cost combination preserves vitamin B6 and folate while adding vitamin B12. Conventional forms, high pyridoxine, and high folate weaken long-term suitability, while N-acetyl L-tyrosine is absent.</p>
89 Value

P-5-P 50 mg

Country Life
<p>Active P-5-P offers stronger form quality at roughly similar serving value. The supplied entries make the total B6 amount unclear, and dropping folate plus N-acetyl L-tyrosine narrows the intended use.</p>
89 Value

BioCoenzymated Pyridoxal 5'-Phosphate 50 mg

Natural Factors
<p>A simple active P-5-P formula provides clear form quality and favorable value for targeted B6 use. Its amount is higher than the original’s, and it does not retain folate or N-acetyl L-tyrosine.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate