Folic Acid B6 & B12
Mason Natural
Folic Acid B6 & B12
4.8
★ ★ ★ ★ ★
(2530 ratings)
Vitamin B12 100 mcg
Vitamin B6 50 mg
Score 70.0
An ultra-affordable supplement providing standard forms of Folic Acid, B6, and B12. Offers foundational B-vitamin support at an excellent price point, though not utilizing the most bioavailable forms.
Quantity: 90 Tablet(s)Servings size: 1 Tablet(s) (90 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 70.0
An ultra-affordable supplement providing standard forms of Folic Acid, B6, and B12. Offers foundational B-vitamin support at an excellent price point, though not utilizing the most bioavailable forms.
insights Analysis
Mason Natural Folic Acid B6 & B12 focuses on providing three key B vitamins crucial for numerous bodily functions, including energy production, nervous system health, and DNA synthesis. The product uses Cyanocobalamin for Vitamin B12 and Pyridoxine Hydrochloride for Vitamin B6. The folate component is listed as Folate (667mcg DFE), which is typically Folic Acid, the synthetic form. While these forms are commonly used and effective for many, nutritionists and some online reviews often highlight the benefits of more bioavailable forms such as Methylcobalamin for B12, Pyridoxal 5-Phosphate for B6, and L-methylfolate for folate, particularly for individuals with compromised methylation pathways. Despite this, the product delivers moderate doses of these vitamins. Its most significant advantage is its extremely low price per serving, making it a highly economical choice for routine supplementation. This product is best suited for individuals seeking simple, budget-friendly B vitamin support.
- Outstanding value due to its exceptionally low price per serving ($0.06), making it highly budget-friendly.
- Provides essential doses of Folic Acid (667mcg DFE), Vitamin B6 (50mg), and Vitamin B12 (100mcg) for daily support.
- Straightforward formulation for general B-vitamin supplementation.
- Utilizes Cyanocobalamin for Vitamin B12, which is not as readily absorbed or utilized as methylcobalamin.
- Contains Pyridoxine Hydrochloride for Vitamin B6, rather than the active Pyridoxal 5-Phosphate (P-5-P) form.
- The folate is likely Folic Acid, which some individuals may struggle to convert to its active form (L-methylfolate).
$5.78($0.06 per serving)
 iHerb | $ 5.78 | |
 Vitacost | $ 5.79 |
bolt Effectiveness for goals
For individuals with a Vitamin B12 deficiency, supplementation can significantly improve energy levels by addressing fatigue caused by the deficiency. B12 is involved in converting food into energy, so a lack of it can lead to tiredness. However, in people without a deficiency, supplementation may not provide an energy boost.
Vitamin B12 is essential for various bodily functions, including red blood cell formation, DNA synthesis, and neurological function. It plays a crucial role in maintaining the health of nerve cells and supporting the production of myelin. Adequate B12 intake helps support overall cellular metabolism.
Vitamin B6, or pyridoxine, is involved in over 100 enzyme reactions, primarily in protein, fat, and carbohydrate metabolism. It plays a critical role in brain development and function, and in the creation of neurotransmitters like serotonin and dopamine. B6 also contributes to immune function and red blood cell production.
Yes, Vitamin B12 is vital for the health and proper functioning of the nervous system. It helps in the production and maintenance of myelin, the protective sheath around nerves. Adequate B12 intake is important for nerve signal transmission and preventing nerve damage.
Vitamin B6 is essential for the synthesis of several key neurotransmitters that regulate mood, sleep, and cognitive function, including serotonin, dopamine, and GABA. It is also involved in the development of the brain and nervous system. Adequate B6 levels are important for maintaining healthy neurological processes.
schedule Dosage, timing & forms
Yes, Vitamin B12 and Vitamin B6 are often included together in B-complex supplements. These vitamins work synergistically in various bodily functions, particularly in supporting nervous system health and homocysteine metabolism. Taking them together is generally considered safe and common practice.
The Recommended Dietary Allowance (RDA) for adults is 2.4 micrograms (mcg) of Vitamin B12 daily. However, dosages in supplements can be much higher, as absorption efficiency decreases with increased intake. Individuals with specific needs, such as deficiencies, may require different amounts as advised by a healthcare professional.
The Recommended Dietary Allowance (RDA) for adults up to age 50 is 1.3 milligrams (mg) of Vitamin B6 daily. For adults over 50, it is 1.7 mg for men and 1.5 mg for women. Higher doses may be used in supplements, but excessive intake over time can lead to adverse effects.
Common forms include cyanocobalamin and methylcobalamin. Cyanocobalamin is a synthetic and stable form often used due to its cost-effectiveness. Methylcobalamin is a naturally occurring active form of B12.
For Vitamin B12, methylcobalamin and adenosylcobalamin are active forms, while cyanocobalamin needs conversion, but all are generally well-absorbed orally. For Vitamin B6, pyridoxal-5-phosphate (P-5-P) is the active form, but pyridoxine HCl is also effectively converted in the body. The best form can vary based on individual metabolism and specific needs.
health_and_safety Safety & interactions
Yes, chronic intake of high doses of Vitamin B6 can lead to peripheral neuropathy, which may cause numbness, tingling, and pain in the hands and feet. Other potential side effects include skin lesions and photosensitivity. It's important to stay within recommended upper limits.
Generally, it is safe to take Vitamin B12 and Vitamin B6 together, as they often work synergistically in the body. Many B-complex supplements contain both vitamins. However, it's crucial to adhere to recommended dosages for each vitamin to avoid potential adverse effects, especially with Vitamin B6.
Vitamin B12 is generally considered safe, even at high doses. Mild side effects are rare but may include headache, nausea, or diarrhea. Allergic reactions are also possible but uncommon.
Yes, the tolerable upper intake level (UL) for Vitamin B6 from supplements and fortified foods for adults is 100 mg per day. Consistently exceeding this limit over a long period increases the risk of developing adverse effects, particularly nerve damage. Adhering to the UL is crucial for safety.
Yes, several medications can interact with Vitamin B6. These include certain anti-epileptic drugs, theophylline, and levodopa, which may alter B6 levels or its effects. Conversely, Vitamin B6 can sometimes affect the efficacy of other drugs. Consult a healthcare provider if you are on medication.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 50 mg |
Folate | 667 mcg DFE |
Vitamin B12 | 100 mcg |
Calcium | 44 mg |
Categories
Vitamin B6 70.0
With 50mg of Vitamin B6, the dosage is robust. Nevertheless, the form is Pyridoxine Hydrochloride, which requires conversion by the body into its active form (P-5-P), making it less efficient for some individuals compared to supplements offering P-5-P directly.
Vitamin B12 65.0
The product offers a functional dose of Vitamin B12 (100mcg) for general needs. However, its use of Cyanocobalamin, a synthetic form, means it is less preferred than methylcobalamin by many who seek optimal bioavailability and direct utilization of the vitamin.
Goals
General Health 72.0
Providing essential B vitamins that support blood cell formation, DNA synthesis, and nerve health, this supplement contributes to overall well-being. Its affordability makes it a practical option for routine general health maintenance.
Metabolism Boost 70.0
As coenzymes, B vitamins are integral to the metabolism of fats, carbohydrates, and proteins. This product supplies the necessary B6, B12, and Folate to aid in these metabolic processes effectively.
Energy 68.0
B vitamins are central to converting food into cellular energy. This product offers a basic supply of B6, B12, and Folate to support these processes, though the forms are not the most efficient for maximizing energy conversion.
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