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Vitamin C Quali-C

4.7
★ ★ ★ ★ ★
(80166 ratings)
Vitamin C 1000 mg
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Score84

A clearly labeled, high-dose vitamin C capsule with good practical value. Sensitive stomachs may do better with a buffered form.

How scoring works
Capsule
Quantity:365 Capsule(s) • (365 servings)
Goals:
Immunity
General Health
Skin Health
Anti-Inflammatory Support
Vision Support

Score 84

A clearly labeled, high-dose vitamin C capsule with good practical value. Sensitive stomachs may do better with a buffered form.

How scoring works

Also available as

1 option
60 servings C 1000 mg • 60 Capsule(s) • 60 servings $8.57 ($0.14 per serving)
$40.88($0.11 per serving)
iHerb
$ 40.88
iHerb
$ 40.88
Report prices

Analysis

Quali-C supplies 1,000 mg of vitamin C in a simple capsule with no competing active ingredients. The amount provides focused antioxidant, immune, and collagen support.

Clear form and dose disclosure are useful strengths. Unbuffered ascorbic acid offers no particular stomach-comfort advantage over mineral ascorbates.

The large supply suits regular users who tolerate acidic vitamin C and want a single-ingredient formula. It remains narrow for goals such as vision or general wellness because it does not cover other nutrient pathways.

Who is it for
  • Adults seeking focused vitamin C support
  • People who prefer one capsule per serving
  • Regular users who tolerate unbuffered ascorbic acid
Best for
  • Antioxidant support
  • Immune support
  • Collagen formation support

Pros

  • Clearly identified Quali-C source
  • Substantial 1,000 mg serving
  • Simple single-active formula
  • Large serving supply

Cons

  • Unbuffered acidic form
  • No complementary nutrients
  • Single large serving may be more than some users need

Warnings

  • A 1,000 mg serving may cause stomach upset or loose stools in sensitive users
  • The unbuffered form may be uncomfortable for people sensitive to acidic supplements
  • Regular high-dose use warrants extra care for people prone to calcium-oxalate kidney stones

Nutrient quality

86 Highest impact

Meaningful vitamin C dosing and a focused formula support the intended use. The unbuffered form offers no absorption or stomach-comfort advantage.

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Ingredient transparency

83 Highest impact

Active ingredients and their amounts are clear, with no proprietary blend hiding key doses. Daily directions and a complete other-ingredients panel are not included in the supplied data.

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Customer satisfaction

72 High impact

The aggregate rating is strong and supported by large feedback volume. Complaint-level experiences are unavailable, so repeated drawbacks and purpose fit remain uncertain.

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Value for money

96 Highest impact

Meaningful servings and strong economy provide practical value. Remaining formula limitations do little to outweigh the low serving cost.

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Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A+ Goal FitA Strength of SupportC CoverageA+ Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports immune-cell activity, barrier function, and antioxidant defense. Human evidence supports vitamin C for maintaining immune function and modestly shortening some respiratory illnesses.

The disclosed vitamin C amount meets the preferred immune-support threshold. The branded source and amount are clear, though unbuffered ascorbic acid lacks enhanced delivery.

Study evidence
Vitamin C Supportive 53 studies
General Health
General Health
Impact
Highest effect
A Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin C · 1000 mg

Branded ascorbic acid provides direct antioxidant, immune, and collagen support at a substantial amount. The simple capsule makes the active and dose easy to understand.

Unbuffered ascorbic acid may be less comfortable for sensitive stomachs than a mineral ascorbate. The formula offers strong depth for vitamin C but does not address broader nutrient gaps.

Study evidence
Vitamin C Supportive 56 studies
Skin Health
Skin Health
Impact
Highest effect
B+ Goal FitA Strength of SupportD+ CoverageA Formula Quality
Vitamin C · 1000 mg

Branded Quali-C ascorbic acid supplies a useful vitamin C amount for collagen formation and antioxidant defense. No barrier-lipid or hydration active is included.

The single-active focus makes its strengths and limits easy to assess. Large vitamin C servings may still cause stomach upset in sensitive users.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Vitamin C · 1000 mg

The 1000 mg vitamin C serving provides substantial antioxidant support from a clearly identified branded source. Its simple capsule format makes the active amount easy to assess.

Unbuffered ascorbic acid offers no advanced delivery and mainly addresses oxidative stress rather than direct inflammatory enzymes. The high acidic dose may cause stomach discomfort in sensitive users.

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
High effect
D+ Goal FitA- Strength of SupportD CoverageB+ Formula Quality
Vitamin C · 1000 mg

Vitamin C contributes retinal antioxidant protection but cannot cover macular pigment or structural needs alone. Vitamin C appears in established ocular nutrient combinations, though standalone evidence is limited for broad vision outcomes.

One gram of vitamin C supplies a meaningful antioxidant amount rather than a token inclusion. Branded Quali-C is clearly identified, though the unbuffered form offers no absorption or stomach-comfort advantage.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Quali-C)
 1000 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Vitamin C (Quali-C) · 1000 mg OverallScore78
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Branded Quali-C provides a clearly identified 1,000 mg vitamin C dose in a simple capsule. The unbuffered ascorbic acid form may be less comfortable for people with sensitive stomachs than mineral ascorbates. Its dose falls within the efficient target range and costs very little per gram.

View ingredientView products
Loading alternative details
86 Performance

Ester-C Plus 1000 mg Vitamin C

Solgar
Ingredient and delivery quality improve with 1,000 mg of buffered Ester-C with 108 mg of calcium and 200 mg of citrus bioflavonoids. Compared with the original 1000 mg vitamin C formula, the substantial buffered dose and compatible bioflavonoids broaden support beyond plain ascorbic acid, although complete excipient details are not supplied.
86 Performance

C

Swanson
Ingredient and delivery quality improve with 1,000 mg of calcium ascorbate with 120 mg of calcium and 200 mg of citrus bioflavonoids. Compared with the original 1000 mg vitamin C formula, the buffered form and meaningful bioflavonoid amount offer a broader formula than plain ascorbic acid, although complete excipient details are not supplied.
84 Performance

Ester-C 24 Hour Immune Support 1000 mg

NatureSmart
Ingredient and delivery quality improve with 1,000 mg of buffered Ester-C with 110 mg of calcium and 102 mg of citrus bioflavonoids. Compared with the original 1000 mg vitamin C formula, the buffered form and bioflavonoids combine stomach-comfort potential with a focused vitamin C dose, although the supplied data do not include the complete inactive-ingredient panel.
89 Budget

Pure Buffered Calcium Ascorbate

NOW
A lower serving cost comes with 890 mg of vitamin C as buffered calcium ascorbate with 100 mg of calcium, compared with the original 1000 mg vitamin C formula. the mineral-bound form may be gentler than plain ascorbic acid and keeps the active formula focused, although the full inactive-ingredient panel is not supplied.
88 Budget

Buffered Gold C

California Gold Nutrition
A lower serving cost comes with 1,000 mg of vitamin C as sodium ascorbate with 130 mg of sodium, compared with the original 1000 mg vitamin C formula. the simple buffered formula provides a full amount with no unrelated active ingredients, although the sodium contribution needs consideration on a restricted diet.
88 Budget

Sodium Ascorbate

NutriBiotic Immunity
A lower serving cost comes with 1,100 mg of vitamin C as sodium ascorbate with 120 mg of sodium, compared with the original 1000 mg vitamin C formula. the fully buffered powder provides a substantial, clearly disclosed amount, although careful measuring and sodium accounting remain important.
87 Value

Pure Buffered Magnesium Ascorbate

NOW
A stronger quality-to-cost balance comes from 820 mg of vitamin C as magnesium ascorbate with 60 mg of magnesium. Compared with the original 1000 mg vitamin C formula, full buffering combines a meaningful vitamin C amount with clear mineral disclosure, while complete use directions and inactive ingredients are not supplied.
84 Value

Ester-C 500 mg With Citrus Bioflavoinds

American Health
A stronger quality-to-cost balance comes from 1,000 mg of buffered Ester-C with a broad citrus bioflavonoid complex. Compared with the original 1000 mg vitamin C formula, the formula adds several named citrus compounds while maintaining a substantial vitamin C amount, while the repeated complex entries make the exact internal amounts difficult to interpret.
87 Value

100% Pure Vitamin C Powder

Swanson Premium Brand
A stronger quality-to-cost balance comes from 1,000 mg of pure ascorbic acid in a flexible powder. Compared with the original 1000 mg vitamin C formula, the single-active formula provides a full vitamin C amount without decorative ingredients, while plain ascorbic acid may be less comfortable for sensitive stomachs.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  2. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  3. Vitamin C supplementation and salivary immune function following exercise-heat stress.
    Carrillo AE; Murphy RJ; Cheung SS · International journal of sports physiology and performance · 2009
    Randomized trial12 participantsImmunity forVitamin C
  4. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  5. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  6. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage.
    Fitzpatrick RE; Rostan EF · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2002
    Non-randomized trial10 participantsSkin Health forVitamin C
  7. Vitamin C and postoperative outcomes following mandibular third molar extraction: a randomized split-mouth study.
    Demirel M; Aktas A; Kizil M; Yalcin N · Oral surgery, oral medicine, oral pathology and oral radiology · 2026
    Randomized trial56 participantsSkin Health forVitamin C
  8. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  9. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  10. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  11. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  12. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  13. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  14. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  15. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  16. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  17. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  18. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  19. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  20. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  21. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  22. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  23. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  24. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  25. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  26. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  27. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  28. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  29. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C