Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Association of vitamin K with cardiovascular events and all-cause mortality: a systematic review and meta-analysis.
Chen HG; Sheng LT; Zhang YB; Cao AL; Lai YW; Kunutsor SK; Jiang L; Pan A · European journal of nutrition · 2020
Meta-analysis222,592 participants21 studies pooledflagHeart Health forscienceVitamin K
- Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
Randomized trial1,874 participantsflagBone Health forscienceVitamin K
- Vitamin K insufficiency predicts incidence of frailty in community-dwelling older adults: The Otassha Study.
Azuma K; Osuka Y; Kojima N; Sasai H; Inoue S · Journal of bone and mineral metabolism · 2023
Cohort study518 participantsflagAnti-Aging forscienceVitamin K
- Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial.
Witham MD; Lees JS; White M; Band M; Bell S; Chantler DJ; Ford I; Fulton RL; Kennedy G; Littleford RC; McCrea IV; McGlynn D; Panarelli M; Ralston MR; Rutherford E; Severn A; Thomson N; Traynor JP; Struthers AD; Wetherall K; Mark PB · Journal of the American Society of Nephrology : JASN · 2021
Randomized trial159 participantsflagHeart Health forscienceVitamin K
- Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
Randomized trial771 participantsflagBone Health forscienceVitamin K
- New Insights into Vitamin K-From Its Natural Sources through Biological Properties and Chemical Methods of Quantitative Determination.
Wianowska D; Bryshten I · Critical reviews in analytical chemistry · 2024
Narrative reviewflagAnti-Aging forscienceVitamin K
- Six weeks phylloquinone supplementation produces undesirable effects on blood lipids with no changes in inflammatory and fibrinolytic markers in postmenopausal women.
Kristensen M; Kudsk J; Bügel S · European journal of nutrition · 2008
Randomized trial31 participantsflagHeart Health forscienceVitamin K
- Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trial.
Cheung AM; Tile L; Lee Y; Tomlinson G; Hawker G; Scher J; Hu H; Vieth R; Thompson L; Jamal S; Josse R · PLoS medicine · 2009
Randomized trial440 participantsflagBone Health forscienceVitamin K
- Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
Meta-analysis3,891 participants3 studies pooledflagAnti-Aging flagGeneral Health forscienceVitamin K
- Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
Cohort study53,372 participantsflagHeart Health flagCardiovascular Support forscienceVitamin K
- Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial244 participantsflagBone Health forscienceVitamin K
- Vitamin K status and cognitive function in healthy older adults.
Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
Cross-sectional study320 participantsflagAnti-Aging forscienceVitamin K
- Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials.
Vlasschaert C; Goss CJ; Pilkey NG; McKeown S; Holden RM · Nutrients · 2021
Systematic review9 studies pooledflagHeart Health forscienceVitamin K
- Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
Meta-analysis6,759 participants19 studies pooledflagBone Health forscienceVitamin K
- The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
Cross-sectional study4,692 participantsflagAnti-Aging forscienceVitamin K
- Vitamin K intake and all-cause and cause specific mortality.
Zwakenberg SR; den Braver NR; Engelen AIP; Feskens EJM; Vermeer C; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Clinical nutrition (Edinburgh, Scotland) · 2018
Cohort study33,289 participantsflagHeart Health forscienceVitamin K
- Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
Meta-analysis13 studies pooledflagBone Health forscienceVitamin K
- High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
Cohort study644 participantsflagAnti-Aging forscienceVitamin K
- Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
Randomized trial92 participantsflagBone Health forscienceVitamin K
- Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
Randomized trial244 participantsflagHeart Health flagCardiovascular Support forscienceVitamin K
- Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
Cross-sectional study85 participantsflagAnti-Aging forscienceVitamin K
- Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women.
Rønn SH; Harsløf T; Pedersen SB; Langdahl BL · European journal of endocrinology · 2017
Randomized trial148 participantsflagBone Health forscienceVitamin K
- Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
Cohort study56,048 participantsflagHeart Health flagCardiovascular Support forscienceVitamin K
- Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases.
Simes DC; Viegas CSB; Araújo N; Marreiros C · Nutrients · 2020
Narrative reviewflagAnti-Aging forscienceVitamin K
- Dietary vitamin K intakes and atherosclerotic cardiovascular disease incidence: Findings from the UK biobank.
Dupuy M; Li C; Pokharel P; Zhong L; Parmenter BH; Radavelli-Bagatini S; Dalla Via J; Linneberg A; Jakobsen J; Kühn T; Cassidy A; Hodgson JM; Lewis JR; Sim M; Bondonno NP · Atherosclerosis · 2026
Cohort study112,111 participantsflagHeart Health forscienceVitamin K
- Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women.
Bolton-Smith C; McMurdo ME; Paterson CR; Mole PA; Harvey JM; Fenton ST; Prynne CJ; Mishra GD; Shearer MJ · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2007
Randomized trial244 participantsflagBone Health forscienceVitamin K
- The role of vitamin K2 in cognitive impairment: linking vascular health to brain health.
Roumeliotis S; Kontogiorgos I; de Vries F; Maresz K; Jeanne JF; Leivaditis K; Schurgers LJ · Frontiers in aging neuroscience · 2025
Narrative reviewflagAnti-Aging forscienceVitamin K
- Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
Meta-analysis6,853 participants9 studies pooledflagBone Health forscienceVitamin K
- The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
Randomized trial149 participantsflagHeart Health forscienceVitamin K
- Vitamin K status in the elderly.
Booth SL · Current opinion in clinical nutrition and metabolic care · 2007
Narrative reviewflagAnti-Aging forscienceVitamin K
- Selenium Concentrations and Mortality among Community-Dwelling Older Adults: Results from IlSIRENTE Study.
Giovannini S; Onder G; Lattanzio F; Bustacchini S; Di Stefano G; Moresi R; Russo A; Bernabei R; Landi F · The journal of nutrition, health & aging · 2019
Cohort study347 participantsflagAnti-Aging forscienceSelenium
- Selenium and mortality in the elderly: results from the EVA study.
Akbaraly NT; Arnaud J; Hininger-Favier I; Gourlet V; Roussel AM; Berr C · Clinical chemistry · 2005
Randomized trialflagAnti-Aging forscienceSelenium
- Association of dietary selenium intake and all-cause mortality of Parkinson's disease and its interaction with blood cadmium level: a retrospective cohort study.
Tu X; Wu N; Wan Y; Gan J; Liu Z; Song L · BMC geriatrics · 2024
Cohort study184 participantsflagAnti-Aging forscienceSelenium
- Selenium alleviates cadmium-induced biological aging acceleration and the potential mediating role of inflammation.
Li C; Xiang Y; Liu M; Wang Z; Wu Y; Yang Q; Huang L · Ecotoxicology and environmental safety · 2025
Cross-sectional study7,433 participantsflagAnti-Aging forscienceSelenium
- Minerals and Sarcopenia; The Role of Calcium, Iron, Magnesium, Phosphorus, Potassium, Selenium, Sodium, and Zinc on Muscle Mass, Muscle Strength, and Physical Performance in Older Adults: A Systematic Review.
van Dronkelaar C; van Velzen A; Abdelrazek M; van der Steen A; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2019
Systematic review10 studies pooledflagAnti-Aging forscienceSelenium
- Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
Randomized trial30 participantsflagAnti-Aging forscienceVitamin K
- Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
Randomized trial454 participantsflagBone Health forscienceVitamin D
- Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
Narrative reviewflagBone Health forscienceVitamin D
- Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
Meta-analysis1,786 participants20 studies pooledflagBone Health forscienceVitamin D
- Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
Randomized trial193 participantsflagBone Health forscienceVitamin D
- Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
Rasool N; Munir Y · European journal of clinical nutrition · 2026
Randomized trial612 participantsflagBone Health forscienceVitamin D
- Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
Randomized trial48 participantsflagBone Health forscienceVitamin K
- Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial.
Rayman MP; Stranges S; Griffin BA; Pastor-Barriuso R; Guallar E · Annals of internal medicine · 2011
Randomized trial501 participantsflagCardiovascular Support flagHeart Health forscienceSelenium
- Association of selenium and cadmium with heart failure and mortality based on the National Health and Nutrition Examination Survey.
Xing X; Xu M; Yang L; Shao C; Wang Y; Qi M; Niu X; Gao D · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
Cohort study15,689 participantsflagCardiovascular Support forscienceSelenium
- Higher serum selenium concentration is associated with lower risk of all-cause and cardiovascular mortality among individuals with chronic kidney disease: A population-based cohort study of NHANES.
Zhu D; Zhong Q; Lin T; Song T · Frontiers in nutrition · 2023
Cohort study3,063 participantsflagCardiovascular Support flagHeart Health forscienceSelenium
- Selenium status in the body and cardiovascular disease: a systematic review and meta-analysis.
Kuria A; Tian H; Li M; Wang Y; Aaseth JO; Zang J; Cao Y · Critical reviews in food science and nutrition · 2021
Meta-analysis13 studies pooledflagCardiovascular Support forscienceSelenium
- Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
Meta-analysis95 participants20 studies pooledflagCardiovascular Support forscienceSelenium
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
Meta-analysisflagCardiovascular Support flagHeart Health forscienceVitamin D
- A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
Randomized trial120 participantsflagCardiovascular Support forscienceVitamin D
- Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
Randomized trial224 participantsflagCardiovascular Support forscienceVitamin D
- Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
Randomized trial70 participantsflagCardiovascular Support forscienceVitamin D
- Paricalcitol and endothelial function in chronic kidney disease trial.
Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
Randomized trial88 participantsflagCardiovascular Support flagHeart Health forscienceVitamin D
- Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
Meta-analysis16 studies pooledflagCardiovascular Support forscienceVitamin E
- Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
Randomized trial90 participantsflagCardiovascular Support forscienceVitamin E
- Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
Randomized trial9,541 participantsflagCardiovascular Support forscienceVitamin E
- Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
Cohort study34,955 participantsflagCardiovascular Support forscienceVitamin E
- Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
Randomized trial62 participantsflagCardiovascular Support forscienceVitamin E
- Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
Randomized trial165 participantsflagCardiovascular Support forscienceVitamin K
- Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
Cohort study55,545 participantsflagCardiovascular Support flagHeart Health forscienceVitamin K
- Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
Cohort study10,882 participantsflagEnergy forscienceIodine
- Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
Cohort study2,584 participantsflagEnergy forscienceIodine
- Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
Cross-sectional study202 participantsflagEnergy forscienceIodine
- Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
Cohort study7,857 participantsflagGeneral Health forscienceVitamin K
- The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
Randomized trial49 participantsflagGeneral Health forscienceVitamin K
- Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
Meta-analysis7 studies pooledflagGeneral Health forscienceVitamin K
- Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
Cohort study1,436 participantsflagGeneral Health forscienceVitamin K
- The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
Patel MN; Maheshvari J; Patel N · Cureus · 2025
Randomized trial105 participantsflagHair Health forscienceBiotin
- Low serum biotinidase activity in children with valproic acid monotherapy.
Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
Clinical trial125 participantsflagHair Health forscienceBiotin
- Vitamins A, B, C, and D: A Short Review for the Dermatologist.
Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
Narrative reviewflagHair Health forscienceBiotin
- The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
Narrative reviewflagHair Health forscienceBiotin
- Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
Randomized trial87 participantsflagHair Health forscienceSelenium
- Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
Observational study1,407 participantsflagHair Health forscienceSelenium
- A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
Randomized trial64 participantsflagHair Health forscienceSelenium
- Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
Meta-analysis764 participantsflagHair Health forscienceSelenium
- Scientific opinion on the tolerable upper intake level for selenium.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
Systematic reviewflagHair Health forscienceSelenium
- The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
Randomized trial200 participantsflagHair Health forscienceZinc
- Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
Randomized trialflagHair Health forscienceZinc
- A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
Randomized trial40 participantsflagHair Health forscienceZinc
- BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
Case-control study216 participantsflagHair Health forscienceZinc
- Analysis of serum zinc and copper concentrations in hair loss.
Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
Case-control study342 participantsflagHair Health forscienceZinc
- Selenium concentration is associated with occurrence and diagnosis of three cardiovascular diseases: A systematic review and meta-analysis.
Yang L; Qi M; Du X; Xia Z; Fu G; Chen X; Liu Q; Sun N; Shi C; Zhang R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
Meta-analysis49 studies pooledflagHeart Health forscienceSelenium
- Exploring the Impact of Selenium Supplementation on Nutritional, Inflammatory, and Cardiac Function in Chronic Heart Failure Patients: A Novel Approach to Managing Deficiency.
Kou L; Meng F; Fu G; Zhang R · Cardiovascular toxicology · 2025
Meta-analysis191 participantsflagHeart Health forscienceSelenium
- Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003-2018.
Shi W; Su L; Wang J; Wang F; Liu X; Dou J · Annals of medicine · 2022
Cross-sectional study39,438 participantsflagHeart Health forscienceSelenium
- Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
Randomized trial1,537 participantsflagHeart Health forscienceVitamin D
- Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
Meta-analysis81 studies pooledflagHeart Health forscienceVitamin D
- Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
Meta-analysis45 studies pooledflagHeart Health forscienceVitamin D
- Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
Randomized trial119 participantsflagImmunity forscienceSelenium
- Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
Randomized trial62 participantsflagImmunity forscienceSelenium
- Chemoprevention trial of human hepatitis with selenium supplementation in China.
Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
Non-randomized trial20,847 participantsflagImmunity forscienceSelenium
- Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
Randomized trial70 participantsflagImmunity forscienceSelenium
- Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
Randomized trial70 participantsflagImmunity forscienceSelenium
- Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagImmunity forscienceVitamin C
- Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
Meta-analysis2,334 participants14 studies pooledflagImmunity forscienceVitamin C
- Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
Meta-analysisflagImmunity forscienceVitamin C
- New evidence for antioxidant properties of vitamin C.
Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
Randomized trial20 participantsflagImmunity forscienceVitamin C
- Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
Calder PC; Kreider RB; McKay DL · Nutrients · 2025
Systematic review13 studies pooledflagImmunity forscienceVitamin C
- Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
Meta-analysis199,055 participants115 studies pooledflagImmunity forscienceZinc
- Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
Randomized trial609 participantsflagImmunity forscienceZinc
- A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
Randomized trial64 participantsflagImmunity forscienceZinc
- The effect of zinc and vitamin A supplementation on immune response in an older population.
Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
Randomized trial136 participantsflagImmunity forscienceZinc
- The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
Systematic review13 studies pooledflagImmunity forscienceZinc