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Iron 65 mg

Nature Made
4.7
★ ★ ★ ★ ★
(56895 ratings)
Iron 65 mg
Product Image
Score77
A tablet that provides 65 mg of iron and is best matched to a demonstrated need. The high amount and digestive risk make casual use a poor fit.
How scoring works
Quantity:180 Tablet(s) • (180 servings)
Goals:
Energy
Hair Health
Productivity Boost

Score 77

A tablet that provides 65 mg of iron and is best matched to a demonstrated need. The high amount and digestive risk make casual use a poor fit.
How scoring works
$7.06($0.03 per serving)
Pure Formulas
$ 9.14
Vitacost
$ 9.17
iHerb
$ 9.44
Walmart
$ 13.18
Amazon
$ 7.06
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Analysis

The 65 mg serving uses ferrous sulfate, an effective but commonly harder-to-tolerate form. The single-ingredient formula includes no vitamin C, folate, or vitamin B12.

Iron may support energy, concentration, and reduced shedding when low iron status is the underlying issue. It is not a general energy, productivity, or hair aid for people whose iron stores are already adequate.

The 65 mg amount is high and better suited to a confirmed need with professional direction. Digestive effects and excess accumulation are meaningful concerns despite the excellent serving value.

Who is it for
  • adults with a demonstrated need for 65 mg of supplemental iron
  • People whose diet or laboratory results indicate low iron
  • People who prefer a tablet
Best for
  • Clinician-directed high-potency iron support
  • Need-based iron intake
  • Budget-conscious long-term supply

Pros

  • Clearly states 65 mg of iron
  • ferrous sulfate is explicitly identified
  • Very low serving cost

Cons

  • The single-ingredient formula includes no vitamin C, folate, or vitamin B12.
  • Iron source is an effective but commonly harder-to-tolerate form
  • No broad pathway coverage beyond iron

Warnings

  • Use the 65 mg iron serving only when iron status or increased need supports supplementation.
  • The high iron amount raises the chance of nausea, constipation, abdominal discomfort, and excess accumulation.
  • Keep the iron supplement securely away from children because accidental overdose can be dangerous.

Nutrient quality

60 Moderate impact

Ferrous sulfate is effective, but it is more likely to cause digestive discomfort than chelated iron. The treatment-level iron amount is excessive for unsupervised routine supplementation.

Ingredient transparency

82 Highest impact

Listed active ingredients have stated amounts, and no proprietary blend hides a combined total. Complete intake directions and inactive ingredients are not supplied, while the iron compound and supporting nutrient names are specific and understandable.

Customer satisfaction

75 High impact

The average rating is strong, and the review count is very large. No review text is supplied to assess recurring complaints or purpose-specific experience.

Value for money

94 Highest impact

The large iron amount and very low cost support value, but the basic sulfate form limits quality. The serving is exceptionally inexpensive for a treatment-level amount.

Report analysis

Goals

Energy
Impact
High effect
A Goal FitC+ Strength of SupportD+ CoverageA Formula Quality
Iron · 65 mg

A high iron amount can meaningfully improve energy when fatigue is caused by iron deficiency or iron-deficiency anemia. Ferrous sulfate is effective and precisely disclosed, but it is not an appropriate general energy aid when iron status is already adequate.

The tablet lacks vitamin C, folate, or B12 cofactors and uses a form that often causes constipation, nausea, or stomach pain. The 65 mg amount should be used for a confirmed need because unnecessary iron can accumulate and accidental ingestion is especially dangerous for children.

Study evidence
Iron Supportive 74 studies
Hair Health
Impact
Moderate effect
B+ Goal FitD Strength of SupportF CoverageB- Formula Quality
Iron · 65 mg

Iron can reduce shedding when low iron stores are the cause. It is not a general hair-growth aid for people with adequate iron.

Ferrous sulfate is effective but often causes nausea or constipation. The high amount should be used for a confirmed need because unnecessary iron can cause toxicity or overload.

Study evidence
Iron Disputed 25 studies
Productivity Boost
Impact
Moderate effect
C- Goal FitC- Strength of SupportF CoverageB- Formula Quality
Iron · 65 mg

Iron can improve fatigue and concentration when low iron status is the cause, but it is not a general cognitive enhancer. The single active supports brain oxygen delivery rather than focus, stress resilience, or neurotransmitter balance.

The 65 mg dose is high and uses ferrous sulfate, which may cause constipation, nausea, or abdominal discomfort. Such a dose is most appropriate when iron need has been established, because unnecessary iron can accumulate and cause harm.

Study evidence
Iron Supportive 69 studies

Ingredients

IngredientAmount per serving
Iron (Ferrous Sulfate)
65 mg
Gluten Free Adults 18–50
Report overview
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Ferrous sulfate supplies a high-potency iron dose at very low cost. Its form and hard tablet format may be harder on the stomach, and no vitamin C or blood-building cofactors are included. The dose reaches the upper end of the high-potency range, so it is more appropriate when that amount is specifically needed.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Clinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial.
    Waldvogel S; Pedrazzini B; Vaucher P; Bize R; Cornuz J; Tissot JD; Favrat B · BMC medicine · 2012
    Randomized trial154 participantsEnergy forIron
  2. Daily iron supplementation on cognitive performance in primary-school-aged children with and without anemia: a meta-analysis.
    Guo XM; Liu H; Qian J · International journal of clinical and experimental medicine · 2015
    Meta-analysis1,825 participants5 studies pooledProductivity Boost forIron
  3. Iron plays a certain role in patterned hair loss.
    Park SY; Na SY; Kim JH; Cho S; Lee JH · Journal of Korean medical science · 2014
    Case-control study420 participantsHair Health forIron
  4. Intravenous iron versus blood transfusion for postpartum anemia: a systematic review and meta-analysis.
    Caljé E; Groom KM; Dixon L; Marriott J; Foon R; Oyston C; Bloomfield FH; Jordan V · Systematic reviews · 2024
    Meta-analysis4,196 participantsEnergy forIron
  5. Scientific Opinion on the substantiation of a health claim related to iron and maintenance of normal hair growth pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusHair Health forIron
  6. The impact of brain iron accumulation on cognition: A systematic review.
    Spence H; McNeil CJ; Waiter GD · PloS one · 2020
    Systematic review41 studies pooledProductivity Boost forIron
  7. Iron deficiency, general health and fatigue: results from the Australian Longitudinal Study on Women's Health.
    Patterson AJ; Brown WJ; Powers JR; Roberts DC · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2001
    Cohort studyEnergy forIron
  8. Iron Status, Anemia, and Iron Interventions and Their Associations with Cognitive and Academic Performance in Adolescents: A Systematic Review.
    Samson KLI; Fischer JAJ; Roche ML · Nutrients · 2022
    Systematic review50 studies pooledProductivity Boost forIron
  9. A Hospital-based Study to Determine Causes of Diffuse Hair Loss in Women.
    Malkud S · Journal of clinical and diagnostic research : JCDR · 2015
    Observational study180 participantsHair Health forIron
  10. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  11. Consumption of Iron-Biofortified Beans Positively Affects Cognitive Performance in 18- to 27-Year-Old Rwandan Female College Students in an 18-Week Randomized Controlled Efficacy Trial.
    Murray-Kolb LE; Wenger MJ; Scott SP; Rhoten SE; Lung'aho MG; Haas JD · The Journal of nutrition · 2017
    Randomized trial150 participantsProductivity Boost forIron
  12. Iron status in diffuse telogen hair loss among women.
    Moeinvaziri M; Mansoori P; Holakooee K; Safaee Naraghi Z; Abbasi A · Acta dermatovenerologica Croatica : ADC · 2010
    Case-control study60 participantsHair Health forIron
  13. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  14. The Effect of Iron-Fortified Lentils on Blood and Cognitive Status among Adolescent Girls in Bangladesh.
    Barnett AL; Wenger MJ; Yunus FM; Jalal C; DellaValle DM · Nutrients · 2023
    Randomized trial359 participantsProductivity Boost forIron
  15. Low iron stores: a risk factor for excessive hair loss in non-menopausal women.
    Deloche C; Bastien P; Chadoutaud S; Galan P; Bertrais S; Hercberg S; de Lacharrière O · European journal of dermatology : EJD · 2008
    Cross-sectional study5,110 participantsHair Health forIron
  16. Maternal Fatigue after Postpartum Anemia Treatment with Intravenous Ferric Carboxymaltose vs. Intravenous Ferric Derisomaltose vs. Oral Ferrous Sulphate: A Randomized Controlled Trial.
    Bombač Tavčar L; Hrobat H; Gornik L; Preložnik Zupan I; Vidmar Šimic M; Pečlin P; Kavšek G; Lučovnik M · Journal of clinical medicine · 2024
    Randomized trial300 participantsEnergy forIron
  17. Efficacy of iron and/or zinc supplementation on cognitive performance of lead-exposed Mexican schoolchildren: a randomized, placebo-controlled trial.
    Rico JA; Kordas K; López P; Rosado JL; Vargas GG; Ronquillo D; Stoltzfus RJ · Pediatrics · 2006
    Randomized trial602 participantsProductivity Boost forIron
  18. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
    Karakoyun Ö; Ayhan E; Yıldız İ · Journal of cosmetic dermatology · 2025
    Cohort study2,851 participantsHair Health forIron
  19. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  20. Randomized, double-blind, placebo-controlled trial of iron supplementation in female soldiers during military training: effects on iron status, physical performance, and mood.
    McClung JP; Karl JP; Cable SJ; Williams KW; Nindl BC; Young AJ; Lieberman HR · The American journal of clinical nutrition · 2009
    Randomized trial219 participantsProductivity Boost forIron
  21. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forIron
  22. Hypophosphatemia attenuates improvements in vitality after intravenous iron treatment in patients with inflammatory bowel disease.
    Bjorner JB; Kennedy N; Lindgren S; Pollock RF · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Randomized trial97 participantsEnergy forIron
  23. Cognitive Performance in Indian School-Going Adolescents Is Positively Affected by Consumption of Iron-Biofortified Pearl Millet: A 6-Month Randomized Controlled Efficacy Trial.
    Scott SP; Murray-Kolb LE; Wenger MJ; Udipi SA; Ghugre PS; Boy E; Haas JD · The Journal of nutrition · 2019
    Randomized trial140 participantsProductivity Boost forIron
  24. The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
    Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
    Case-control study100,203 participantsHair Health forIron
  25. Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration.
    Krayenbuehl PA; Battegay E; Breymann C; Furrer J; Schulthess G · Blood · 2011
    Randomized trial90 participantsEnergy forIron
  26. Effects of iron and n-3 fatty acid supplementation, alone and in combination, on cognition in school children: a randomized, double-blind, placebo-controlled intervention in South Africa.
    Baumgartner J; Smuts CM; Malan L; Kvalsvig J; van Stuijvenberg ME; Hurrell RF; Zimmermann MB · The American journal of clinical nutrition · 2013
    Randomized trial321 participantsProductivity Boost forIron
  27. Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
    Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
    Cohort study261 participantsHair Health forIron
  28. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  29. Iron-deficiency anaemia and its effect on worker productivity and activity patterns.
    Edgerton VR; Gardner GW; Ohira Y; Gunawardena KA; Senewiratne B · British medical journal · 1980
    Non-randomized trialProductivity Boost forIron
  30. Alopecia Areata Different View; Heavy Metals.
    Ozaydin-Yavuz G; Yavuz IH; Demir H; Demir C; Bilgili SG · Indian journal of dermatology · 2024
    Case-control study61 participantsHair Health forIron
  31. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  32. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
    Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
    Meta-analysis10,029 participants36 studies pooledHair Health forIron
  33. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
    Cross-sectional study100 participantsHair Health forIron
  34. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
    Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
    Cohort study155 participantsHair Health forIron
  35. Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials.
    Low M; Farrell A; Biggs BA; Pasricha SR · CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
    Meta-analysis7,089 participants32 studies pooledProductivity Boost forIron
  36. Functional consequences of iron supplementation in iron-deficient female cotton mill workers in Beijing, China.
    Li R; Chen X; Yan H; Deurenberg P; Garby L; Hautvast JG · The American journal of clinical nutrition · 1994
    Randomized trial80 participantsProductivity Boost forIron
  37. Daily iron supplementation for improving anaemia, iron status and health in menstruating women.
    Low MS; Speedy J; Styles CE; De-Regil LM; Pasricha SR · The Cochrane database of systematic reviews · 2016
    Meta-analysis8,506 participants67 studies pooledProductivity Boost forIron