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Resveratrol

ZHOU
4.6
★ ★ ★ ★ ★
(967 ratings)
Resveratrol 1000 mg
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Score73

Exceptionally high trans-resveratrol exposure is clearly disclosed but too aggressive for most routine users.

How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Anti-Aging
Cardiovascular Support
Anti-Inflammatory Support
Skin Health

Score 73

Exceptionally high trans-resveratrol exposure is clearly disclosed but too aggressive for most routine users.

How scoring works
$21.99($0.73 per serving)
Pure Formulas
$ 25.69
iHerb
$ 25.69
Vitacost
$ 25.69
Amazon
$ 21.99
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Analysis

The capsule serving supplies 1,000 mg trans-resveratrol from Japanese knotweed. Clear isomer and source disclosure make the active easy to identify.

The amount is far higher than most products in this group and does not use an enhanced-delivery system. Higher exposure may increase digestive effects without guaranteeing proportionally better support.

It may suit a professionally reviewed high-dose protocol, not casual anti-aging or metabolism use. Two capsules and only 30 servings further reduce everyday practicality.

Who is it for
  • Adults following a professionally reviewed high-dose plan
  • Users who specifically need concentrated trans-resveratrol
  • People who tolerate Japanese knotweed extracts
Best for
  • Short monitored high-dose protocols
  • Users prioritizing active isomer disclosure
  • Situations where dose intensity matters more than gentleness

Pros

  • Provides 1,000 mg trans-resveratrol
  • Identifies Japanese knotweed source
  • Clear active-isomer disclosure
  • Focused formula

Cons

  • Dose is unnecessarily high for routine use
  • No enhanced absorption system
  • Emodin removal is not verified
  • Only 30 servings

Warnings

  • High-dose resveratrol may increase bleeding tendency with anticoagulant or antiplatelet medicines
  • Japanese knotweed without emodin-removal verification may cause laxative effects
  • The 1,000 mg amount may cause digestive discomfort and should not be used casually

Nutrient quality

75 High impact

The clearly named trans isomer and substantial amount provide strong active depth. An unusually aggressive dose, standard delivery, and incomplete purity information weaken routine suitability.

Ingredient transparency

64 Moderate impact

The label names the main actives and avoids a broad hidden blend. Repeated entries, missing active yields, absent directions, and undisclosed excipients reduce clarity.

Customer satisfaction

70 High impact

The supplied average rating is strong and the rating volume is substantial. No specific experience details were provided to judge repeated complaints or purpose alignment.

Value for money

87 Highest impact

The formula provides fair value for its cost. It compares well within the category despite remaining formulation limits.

Report analysis

Goals

Anti-Aging
Anti-Aging
Impact
High effect
B- Goal FitC+ Strength of SupportB- CoverageA Formula Quality

Trans-resveratrol targets oxidative, vascular, and sirtuin-related pathways linked with aging. The amount is above the usual target range, and human evidence for extending healthspan remains inconsistent.

Active yield is clearly disclosed, but the capsule lacks absorption technology and emodin-free verification. The high Japanese knotweed-derived amount may increase digestive upset, especially if residual emodin is present.

Study evidence
Resveratrol No effect 7 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
C Goal FitB+ Strength of SupportC- CoverageA- Formula Quality

Trans-resveratrol may support endothelial signaling and antioxidant defenses, but human cardiovascular results are inconsistent. It should be viewed as an adjunct rather than a foundation for lipid or blood-pressure support.

The plant source and trans form are named at a very large amount, although the repeated listing makes the true form contribution unclear. Resveratrol may increase bleeding tendency with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 73 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitC+ Strength of SupportD CoverageA+ Formula Quality

Trans-resveratrol may support SIRT1 and NF-kB signaling relevant to metabolic and age-related inflammation. Human findings are mixed, and absorption is a major limitation for standard oral resveratrol.

The 1,000 mg amount is unusually high and may cause nausea, diarrhea, or abdominal discomfort. No lipid carrier or advanced delivery method is disclosed, and resveratrol may increase bleeding risk with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 34 studies
Skin Health
Skin Health
Impact
High effect
C+ Goal FitC- Strength of SupportD+ CoverageA- Formula Quality
Resveratrol · 1000 mg

Trans-resveratrol provides antioxidant support that may help the skin handle environmental stress. Its evidence for visible skin outcomes is less direct than the evidence for established structural or hydration actives.

The unusually large serving lacks an absorption aid and emodin-free verification. People taking anticoagulants should discuss this high resveratrol intake with a clinician because it may increase bleeding risk.

Study evidence
Resveratrol Supportive 7 studies
Metabolism Boost
Metabolism Boost
Impact
Moderate effect
C- Goal FitC Strength of SupportD+ CoverageB+ Formula Quality
Resveratrol · 1000 mg

Trans-resveratrol may influence insulin signaling and mitochondrial regulation, giving it a plausible metabolism role. Human findings are inconsistent, and poor oral bioavailability limits confidence in a meaningful metabolism boost.

The high amount is clearly disclosed but sits above common supportive use and lacks an absorption-enhancing delivery system. Japanese knotweed without emodin-removal verification may cause digestive upset, and the high resveratrol exposure may increase bruising risk with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 21 studies

Ingredients

IngredientAmount per serving
Resveratrol (Polygonum cuspidatum, Trans-Resveratrol)
 1000 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Resveratrol (Polygonum cuspidatum, Trans-Resveratrol) · 1000 mg OverallScore72
C Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value

The label clearly provides trans-resveratrol and pairs it with its Japanese knotweed source. The 1000 mg serving is above the usual target range and may be harder to tolerate, while the capsule lacks advanced absorption technology. Active-dose value is excellent, but the absence of emodin-free verification is a notable safety gap.

View ingredientView products
Loading alternative details
81 Performance

Resveratrol 500 mg

Solgar
<p>Its ingredient profile and goal alignment make it a stronger formulation-focused alternative. A substantial amount of clearly identified trans-resveratrol gives this focused formula meaningful depth. Standard capsule delivery and missing source and purity details limit refinement, while the dose remains economical for the category.</p>
80 Performance

Resveratrol Plus

Country Life
<p>Its ingredient profile and goal alignment make it a stronger formulation-focused alternative. A supportive trans-resveratrol dose is paired with grape and pine polyphenols for broader antioxidant coverage. The economical large format improves value, though incomplete standardization and knotweed without emodin-removal verification leave potency and tolerability uncertainty.</p>
80 Performance

TransMax TR

Biotivia
<p>Its ingredient profile and goal alignment make it a stronger formulation-focused alternative. MicroActive delivery directly addresses resveratrol absorption while providing a substantial trans-resveratrol amount. The high price buys meaningful delivery technology, but missing purity and emodin-removal details leave tolerability uncertainty for the knotweed source.</p>
83 Budget

High Potency Trans-Resveratrol 600 mg

Doctor's Best
<p>The lower serving cost makes this a more economical alternative. A high amount of clearly identified trans-resveratrol provides strong depth at a favorable cost. Basic capsule delivery and missing purity and emodin-removal details limit refinement, while the high dose may increase stomach upset or bleeding tendency with anticoagulant or antiplatelet medicines.</p>
81 Budget

Resveratrol 250 mg with Red Wine Extract

Solgar
<p>The lower serving cost makes this a more economical alternative. A meaningful trans-resveratrol amount in a fat-containing softgel offers better delivery potential than a plain powder capsule. The larger package improves serving value, although purity details remain incomplete and resveratrol may add bleeding risk with anticoagulant or antiplatelet medicines.</p>
80 Budget

Resveratrol 100 mg

Life Extension
<p>The lower serving cost makes this a more economical alternative. Trans-resveratrol from grape and knotweed plus quercetin creates a focused antioxidant combination at a low serving cost. Duplicate source entries make the total active amount unclear, and missing purity and emodin-removal details limit dose and tolerability confidence.</p>
78 Value

Resveratrol 100 mg

Jarrow Formulas
<p>The balance of ingredient quality and serving economy makes it a stronger value choice. A long supply of resveratrol and vitamin C offers economical, modest antioxidant support. Unconfirmed trans-isomer content, standard capsule delivery, and missing emodin-removal detail limit confidence in effective exposure.</p>
72 Value

Resveratrol With Pterostilbene 100 mg

Life Extension
<p>The balance of ingredient quality and serving economy makes it a stronger value choice. Trans-resveratrol and quercetin provide useful antioxidant support, but the repeated resveratrol entries make the total active amount ambiguous. Trace pterostilbene adds little practical value, while knotweed without emodin-removal verification may cause loose stools in sensitive users.</p>
72 Value

Resveratrol

youtheory
<p>The balance of ingredient quality and serving economy makes it a stronger value choice. A useful trans-resveratrol amount provides meaningful antioxidant coverage at an efficient serving cost. Pressed-tablet delivery, missing emodin verification, and an opaque fruit blend are the main limitations.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
    Witte AV; Kerti L; Margulies DS; Flöel A · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Randomized trial46 participantsAnti-Aging forResveratrol
  2. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsAnti-Aging forResveratrol
  3. Resveratrol levels and all-cause mortality in older community-dwelling adults.
    Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C · JAMA internal medicine · 2014
    Cohort study783 participantsAnti-Aging forResveratrol
  4. Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
    Mansouri F; Feliziani G; Bordoni L; Gabbianelli R · Journal of the Academy of Nutrition and Dietetics · 2025
    Meta-analysis11 studies pooledAnti-Aging forResveratrol
  5. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.
    Rao A; Briskey D; Roche G; Tremblay A; Da Silva Pinto M; Tompkins TA · Frontiers in aging · 2026
    Randomized trial134 participantsAnti-Aging Skin Health forResveratrol
  6. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  7. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  8. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  9. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsAnti-Inflammatory Support forResveratrol
  10. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  11. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; García-Almagro FJ; Avilés-Plaza F; Parra S; Yáñez-Gascón MJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · Molecular nutrition & food research · 2012
    Randomized trial75 participantsCardiovascular Support forResveratrol
  12. Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.
    Ahmadi P; Akbarzadeh S; Alizadeh M; Mohammadi N; Mahmoodi M; Amini A; Netticadan T; Rezaei M; Movahed A · Molecular and cellular biochemistry · 2025
    Randomized trial60 participantsCardiovascular Support forResveratrol
  13. Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases.
    Shen CY; Li CP; Yu JT; Ho YJ; Tsai RY · In vivo (Athens, Greece) · 2026
    Meta-analysis2,551 participants40 studies pooledCardiovascular Support forResveratrol
  14. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
    Wong RH; Berry NM; Coates AM; Buckley JD; Bryan J; Kunz I; Howe PR · Journal of hypertension · 2014
    Randomized trial28 participantsCardiovascular Support forResveratrol
  15. Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind, placebo-controlled trial.
    Simental-Mendía LE; Guerrero-Romero F · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Randomized trial71 participantsCardiovascular Support forResveratrol
  16. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.
    Zhu X; Wu C; Qiu S; Yuan X; Li L · Nutrition & metabolism · 2022
    Meta-analysis283 participants9 studies pooledMetabolism Boost forResveratrol
  17. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
    Sun JN; Yang R; Fang L; Li YJ; Xing WY; Sun ML; Wu L; Wu QJ; Gong TT · Nutrition journal · 2026
    Meta-analysis45 studies pooledMetabolism Boost forResveratrol
  18. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
    Chen S; Zhao X; Ran L; Wan J; Wang X; Qin Y; Shu F; Gao Y; Yuan L; Zhang Q; Mi M · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015
    Randomized trial60 participantsMetabolism Boost forResveratrol
  19. Supplementation with resveratrol modified gut microbiota improving insulin sensitivity and lipid metabolism in subjects with obesity and insulin resistance.
    Guevara-Cruz M; Sánchez-Tapia M; Velazquez-Villegas LA; Torre-Villalvazo I; Guizar-Heredia R; Godínez-Salas E; López-Barradas A; Granados O; Torres-Villalobos G; Torres N; Tovar AR · European journal of nutrition · 2026
    Randomized trial32 participantsMetabolism Boost forResveratrol
  20. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
    Zhou Q; Wang Y; Han X; Fu S; Zhu C; Chen Q · Frontiers in physiology · 2022
    Meta-analysis1,171 participants25 studies pooledMetabolism Boost forResveratrol
  21. Efficacy and safety of Resveratrol combined with Ablative Fractional CO2 laser system in the treatment of skin photoaging.
    Du YM; Zeng J; Li M; Wang YB; Wu Y; Qi RQ; Gao XH; Chen HD · Journal of cosmetic dermatology · 2021
    Non-randomized trial32 participantsSkin Health forResveratrol
  22. Exploring resveratrol-enriched collagen dressings for diabetic foot ulcers: A retrospective study of wound healing outcomes.
    Sezikli İ; Kendirci M · Journal of tissue viability · 2025
    Cohort study41 participantsSkin Health forResveratrol
  23. Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
    Moyano-Mendez JR; Fabbrocini G; De Stefano D; Mazzella C; Mayol L; Scognamiglio I; Carnuccio R; Ayala F; La Rotonda MI; De Rosa G · Drug development and industrial pharmacy · 2016
    Clinical trialSkin Health forResveratrol
  24. Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.
    Montenegro L; Parenti C; Turnaturi R; Pasquinucci L · Pharmaceutics · 2020
    Clinical trial12 participantsSkin Health forResveratrol