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Adrenal Serenity

Natural Factors Stress-Relax
4.7
★ ★ ★ ★ ★
(6128 ratings)
Ashwagandha 250 mg
Eleuthero 150 mg
Rhodiola
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Score81
A well-characterized ashwagandha core and lavender make this a practical calming adaptogen blend. Rhodiola is present only as a light supporting ingredient.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Cognitive Support

Score 81

A well-characterized ashwagandha core and lavender make this a practical calming adaptogen blend. Rhodiola is present only as a light supporting ingredient.
How scoring works
$13.27($0.44 per serving)
Vitacost
$ 13.27
Amazon
$ 13.27
iHerb
$ 13.27
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Analysis

Sensoril ashwagandha provides a well-characterized foundation, while lavender supports the calming side of the formula. Eleuthero adds daytime resilience and is identified with an active marker.

Rhodiola is clearly included but sits below the main stand-alone range. The mix therefore leans more toward calm stress adaptation than energetic performance or acute focus.

Two capsules per serving and good routine value make the product easy to use consistently. It fits people who want a calmer adaptogen profile without a very long ingredient list.

Who is it for
  • Adults seeking calm stress support
  • Users who value branded Sensoril
  • People wanting a concise adaptogen formula
Best for
  • Stress resilience
  • Calm daytime support
  • Users sensitive to more aggressive energy blends

Pros

  • Clinically studied Sensoril extract
  • Lavender complements the calming goal
  • Good routine value

Cons

  • Rhodiola amount is low
  • Not designed for a strong energy effect
  • Marker percentages are not fully shown

Warnings

  • Ashwagandha warrants professional guidance during pregnancy or when thyroid or liver concerns are present.
  • Rhodiola, eleuthero, or ginseng may feel stimulating and can be a poor fit near bedtime or with other stimulants.
  • Introduce multi-herb adaptogen blends cautiously because sensitivity to one ingredient can be difficult to identify.

Nutrient quality

82 Highest impact

Sensoril is a well-characterized ashwagandha extract, while the supporting extracts have fewer potency details. Sensoril is meaningfully dosed, eleuthero is supportive, and rhodiola is below a strong targeted range.

Ingredient transparency

78 High impact

Specific amounts are disclosed for all four active extracts. Non-active capsule ingredients are not disclosed in the provided facts.

Customer satisfaction

72 High impact

The supplied average rating is strong. The large rating sample provides strong statistical confidence.

Value for money

92 Highest impact

A clinically studied ashwagandha extract and a focused supporting blend justify the serving cost well. The favorable serving cost includes a meaningful Sensoril amount and three supporting botanicals.

Report analysis

Goals

Cognitive Support
Cognitive Support
Impact
Highest effect
A- Goal FitB Strength of SupportB CoverageA- Formula Quality
Ashwagandha · 250 mg

Adrenal Serenity aligns with Cognitive Support mainly through Ashwagandha and Rhodiola, while the supplied collection analyses average 79.5 and supplied customer feedback is 4.68 from 6,063 reviews.

Its strongest feature is form and disclosure quality, while some goal-relevant amounts are modest; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha Supportive 17 studies
Rhodiola Supportive 7 studies

Ingredients

IngredientAmount per serving
Sensoril Ashwagandha extract
250 mg
Eleuthero extract
150 mg
Lavender extract
150 mg
Rhodiola extract
75 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
Ashwagandha · 250 mg OverallScore88
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

Reported customer feedback averages 4.68 out of 5 across 6,063 reviews. A clinically studied branded extract provides strong ingredient-form quality; the disclosed amount aligns with the applicable rubric target, while the exact milligram quantity is transparent. Ashwagandha may affect thyroid function and has rare liver-injury reports, so pregnancy, thyroid or liver concerns, and potentially interacting medicines warrant clinician guidance.

View ingredientView products
Eleuthero · 150 mg OverallScore88
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB+ Value

The 150 mg Eleuthero root extract is standardized to 0.8% eleutherosides and fully disclosed. Its $0.44 serving price is favorable for the collection, although the dose is still below the rubric's 300 mg full-credit threshold.

View ingredientView products
Rhodiola · 75 mg OverallScore63
A- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value

Adrenal Serenity provides 75 mg of Rhodiola rosea root extract, and both active markers are present, although the profile differs from the preferred 3:1 target. The amount is individually disclosed but sits below the main target range. Customer feedback averages 4.68 across 6,063 reviews; the official label reports no artificial colors or sweeteners and advises clinician review with medication or medical conditions.

View ingredientView products
Loading alternative details
81 Performance

AdrenaSense

Natural Factors WS WomenSense
A clearly listed 200.00mg of Rhodiola extract as Rosavins offers a credible quality-focused alternative to the original formula. The supplied analyses show good alignment with the stated mood support goal, although they do not establish a clear overall upgrade over the original.
73 Performance

HPA Adapt

Integrative Therapeutics
A clearly listed 200.00mg of Holy Basil (Ocimum sanctum) leaf extract as Ursolic Acid offers a credible quality-focused alternative to the original formula. The supplied analyses show good alignment with the stated stress relief goal, although they do not establish a clear overall upgrade over the original.
73 Performance

Daily Stress Formula

Pure Encapsulations
A clearly listed 250.00mg of Vitamin C as Ascorbic Acid offers a credible quality-focused alternative to the original formula. The supplied analyses show good alignment with the stated stress relief goal, although they do not establish a clear overall upgrade over the original.
79 Budget

Dual Ginseng Plus

Swanson Superior Herbs
Lower serving cost makes this a more economical choice than the original formula. It still provides a clearly listed 200.00mg of American Ginseng root extract as Ginsenosides, retaining a relevant active rather than cutting cost through an unrelated product.
67 Budget

Adrenal Optimizer

Jarrow Formulas
Lower serving cost makes this a more economical choice than the original formula. It still provides a clearly listed 100.00mg of Vitamin C as Calcium Ascorbate, retaining a relevant active rather than cutting cost through an unrelated product.
62 Budget

Yohimbe-Plus Maximum Enhancement

Irwin Naturals
Lower serving cost makes this a more economical choice than the original formula. It still provides a clearly listed 20.00Calorie(s) of Calories, retaining a relevant active rather than cutting cost through an unrelated product.
77 Value

Energy Xtra

Pure Encapsulations
A clearly listed 200.00mg of Ashwagandha (Withania somnifera) extract as Withanolides pairs useful collection fit with a relatively modest serving cost among eligible choices, creating a balanced quality-to-cost trade-off. Its supplied analyses show good alignment with the stated cognitive support goal, though the available data do not document certification or testing.
78 Value

Saffron

youtheory
A clearly listed 350.00mg of Rhodiola (root) extract pairs useful collection fit with a relatively modest serving cost among eligible choices, creating a balanced quality-to-cost trade-off. Its supplied analyses show good alignment with the stated productivity boost goal, though the available data do not document certification or testing.
68 Value

Stress Remedy

Pure Synergy
A clearly listed 600.00mg of SuperPure Ashwagandha root extract pairs useful collection fit with a relatively modest serving cost among eligible choices, creating a balanced quality-to-cost trade-off. Its supplied analyses show good alignment with the stated general health goal, though the available data do not document certification or testing.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsCognitive Support forAshwagandha
  2. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsCognitive Support forAshwagandha
  3. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support forAshwagandha
  4. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support forAshwagandha
  5. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsCognitive Support forAshwagandha
  6. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support forRhodiola
  7. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsCognitive Support forRhodiola
  8. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  9. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support forRhodiola
  10. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support forRhodiola