Product Image

HPA Adapt

Integrative Therapeutics
4.8
★ ★ ★ ★ ★
(53 ratings)
Eleuthero 300 mg
Ashwagandha 300 mg
Rhodiola
Product Image
Score73
High-dose rhodiola, Sensoril, and eleuthero make this a potent broad adaptogen blend. Cost, serving burden, and incomplete marker percentages are the trade-offs.
How scoring works
Quantity:120 Capsule(s) • (30 servings)
Goals:
Stress Relief
Mood Support
Productivity Boost
Brain Health
Mental Focus
Energy
Cognitive Support
Testosterone Support

Score 73

High-dose rhodiola, Sensoril, and eleuthero make this a potent broad adaptogen blend. Cost, serving burden, and incomplete marker percentages are the trade-offs.
How scoring works
$39.50($1.31 per serving)
Pure Formulas
$ 39.50
Report prices

Analysis

Rhodiola, Sensoril ashwagandha, and eleuthero all reach substantial amounts, giving the formula real depth across stress resilience, energy, and focus. Holy basil and branded maca broaden the mood and vitality support.

Several marker names are supplied, but their percentages are not consistently clear, so extract potency cannot be compared precisely. The complex label also leaves non-active ingredients and some duplicated marker presentation ambiguous.

Four capsules per serving and premium cost are meaningful practical drawbacks. It best suits experienced adaptogen users who want high-dose breadth and can tolerate a more activating daytime formula.

Who is it for
  • Experienced adaptogen users
  • Adults seeking strong daytime stress support
  • People willing to take four capsules
Best for
  • Stress resilience
  • Daytime energy and mental focus
  • Broad high-dose adaptogen routines

Pros

  • Substantial amounts of three core adaptogens
  • Includes branded Sensoril and maca extracts
  • Strong formulation coherence

Cons

  • Four-capsule serving
  • High serving cost
  • Marker percentages remain incomplete

Warnings

  • Ashwagandha warrants professional guidance during pregnancy or when thyroid or liver concerns are present.
  • Rhodiola, eleuthero, or ginseng may feel stimulating and can be a poor fit near bedtime or with other stimulants.
  • Introduce multi-herb adaptogen blends cautiously because sensitivity to one ingredient can be difficult to identify.

Nutrient quality

85 Highest impact

Sensoril and branded maca add strong form detail, while several botanical markers are named without their strengths. Rhodiola, ashwagandha, and eleuthero reach substantial extract amounts with meaningful supporting botanicals.

Ingredient transparency

81 Highest impact

All listed actives have disclosed amounts despite repeated marker entries in the supplied data. Non-active ingredients are not provided.

Customer satisfaction

64 Moderate impact

The supplied average rating is very strong. The small rating sample limits confidence in the average.

Value for money

56 Moderate impact

Substantial, well-identified extracts provide high formula quality despite incomplete marker strengths. The high serving cost limits value even with strong lead doses.

Report analysis

Goals

Stress Relief
Impact
Highest effect
A+ Goal FitA Strength of SupportB+ CoverageA Formula Quality
Ashwagandha · 300 mgEleuthero · 300 mg

Sensoril ashwagandha, rhodiola, eleuthero, holy basil, and maca provide broad adaptogen support for stress resilience and stress-related fatigue. The main amounts are substantial and the botanical identities are clear.

Several active markers are named, although their percentages are not provided. Rhodiola and eleuthero can feel activating for some users, so timing may matter when stress also disrupts sleep.

Study evidence
Ashwagandha Supportive 47 studies
Eleuthero No effect 1 study
Rhodiola Supportive 16 studies
Mood Support
Impact
Highest effect
A Goal FitA Strength of SupportA- CoverageA Formula Quality
Ashwagandha · 300 mg

Sensoril ashwagandha, Rhodiola, eleuthero, holy basil, and maca provide broad stress-response and resilience support. Most amounts are substantial and the formula is clearly designed around HPA-axis adaptation.

Rhodiola marker percentages are not stated, and the extensive adaptogen list creates some overlap. The combination remains coherent for stress-related mood support rather than direct serotonin modulation.

Study evidence
Ashwagandha Supportive 29 studies
Rhodiola Supportive 15 studies
Productivity Boost
Impact
Highest effect
A- Goal FitA- Strength of SupportB+ CoverageA Formula Quality
Eleuthero · 300 mgEleuthero · 300 mg

Rhodiola, Sensoril ashwagandha, eleuthero, holy basil, and maca create a strong adaptogen formula for stress-related fatigue. The blend targets resilience rather than immediate stimulation or neurotransmitter precursors.

The main adaptogens are supplied at useful amounts, and several recognized extracts or active markers are named. Missing marker percentages limit precision, but the formula remains coherent and deeply aligned with sustained productivity under stress.

Study evidence
Ashwagandha Supportive 6 studies
Eleuthero No effect 1 study
Eleuthero Not classified

No linked studies yet.

Rhodiola Supportive 7 studies
Brain Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB+ CoverageB+ Formula Quality
Ashwagandha · 300 mg

Rhodiola and Sensoril ashwagandha provide strong adaptogen support for mental fatigue and stress resilience. Eleuthero, holy basil, and maca broaden the stress-response strategy.

Amounts are substantial and several species or branded sources are identified. Missing active-marker percentages prevent confirmation of the preferred rhodiola ratio and the potency of some secondary extracts.

Study evidence
Ashwagandha Supportive 12 studies
Rhodiola Supportive 8 studies
Mental Focus
Impact
Highest effect
B+ Goal FitA- Strength of SupportA- CoverageA- Formula Quality

Substantial amounts of Rhodiola rosea, Sensoril ashwagandha, and eleuthero make this a strong adaptogen formula for mental stamina under pressure. Holy basil and branded maca add further stress and fatigue support without crowding the core.

The blend lacks an acute alertness or neurotransmitter-precursor ingredient, so its fit is strongest when stress drives poor focus. Species, plant parts, brands, and exact amounts are unusually clear, though botanical marker percentages remain incomplete.

Study evidence
Ashwagandha Supportive 12 studies
Eleuthero Disputed 3 studies
Rhodiola Supportive 15 studies
Energy
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageA Formula Quality

Rhodiola, Sensoril ashwagandha, eleuthero, holy basil, and maca create a focused stress-resilience formula. The major adaptogens have substantial amounts and several named active markers.

Marker percentages are missing for important extracts, which prevents confirmation of full standardization. The formula strongly covers stress-related fatigue but does not provide a separate metabolic or acute-alertness pathway.

Study evidence
Ashwagandha Supportive 9 studies
Eleuthero Disputed 3 studies
Rhodiola Supportive 18 studies

Ingredients

IngredientAmount per serving
Total Carbohydrates
1 Gram(s)
Rhodiola (Rhodiola rosea) root extract (Rosavins, Salidroside)
400 mg
Ashwagandha (Withania somnifera) (Sensoril brand) root and leaf extract
300 mg
Eleuthero (Eleutherococcus senticosus) root extract (Eleutherosides)
300 mg
Holy Basil (Ocimum sanctum) leaf extract (Ursolic Acid, Triterpenoic Acids, Oleanolic Acid)
200 mg
MacaPure brand Maca (Lepidium meyenii) root extract (Macaenes, Macamides)
150 mg
Gluten Free Adults 18–50 Dairy Free Women Vegetarian
Report overview
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The root source and eleutherosides are both identified, although the active-marker percentage is missing. A clearly disclosed 300 mg amount reaches the preferred standardized-extract range in two capsules. The formulation is potent and transparent, but its relatively high serving cost limits value.

Ashwagandha · 300 mg OverallScore76
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
+4

A clinically studied Sensoril extract provides strong form quality at a slightly high but still reasonable dose. The exact amount is disclosed, while the formula lacks a dedicated absorption enhancer. The substantial cost premium and broader adaptogen focus weaken its ashwagandha-specific value.

A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
+1

Rhodiola rosea root extract is supplied at a substantial amount with both rosavins and salidroside named. Marker percentages are missing, so the preferred ratio cannot be confirmed. Cost per standardized amount is high, and the supplied data do not show whether the capsule excipients are clean.

Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support Energy forAshwagandha
  2. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  3. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  4. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  5. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Sleep Support Stress Relief forAshwagandha
  6. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Fitness Mental Focus forRhodiola
  7. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  8. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  9. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health General Health Productivity Boost forRhodiola
  10. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  11. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  12. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  13. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
    Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
    Randomized trial144 participantsCognitive Support Mental Focus Productivity Boost Stress Relief forEleuthero
  14. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola Energy Mental Focus forEleuthero
  15. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  16. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support Stress Relief forRhodiola
  17. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  18. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsEnergy Mood Support forAshwagandha
  19. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
    Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
    Randomized trialEnergy forAshwagandha
  20. Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
    Vittal M; Vinciguerra M · Biogerontology · 2025
    Narrative reviewEnergy forAshwagandha
  21. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsEnergy Productivity Boost forAshwagandha
  22. Randomized controlled trial of Siberian ginseng for chronic fatigue.
    Hartz AJ; Bentler S; Noyes R; Hoehns J; Logemann C; Sinift S; Butani Y; Wang W; Brake K; Ernst M; Kautzman H · Psychological medicine · 2004
    Randomized trial96 participantsEnergy forEleuthero
  23. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human
    J Kuo, K W Chen, I S Cheng, P H Tsai, Y J Lu, N Y Lee · Chinese Journal of Physiology · 2010
    Randomized trial9 participantsEnergy forEleuthero
  24. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy Fitness forRhodiola
  25. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Fitness Mental Focus forRhodiola
  26. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  27. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy General Health Stress Relief forRhodiola
  28. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy Fitness forRhodiola
  29. Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial.
    Ziegenfuss TN; Kedia AW; Sandrock JE; Raub BJ; Kerksick CM; Lopez HL · Nutrients · 2019
    Randomized trial38 participantsFitness forAshwagandha
  30. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
    Choudhary B; Shetty A; Langade DG · Ayu · 2016
    Randomized trial50 participantsFitness General Health forAshwagandha
  31. Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
    Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
    Randomized trial80 participantsFitness General Health Muscle Gain forAshwagandha
  32. Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
    Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
    Meta-analysis1,249 participants20 studies pooledFitness Muscle Gain Testosterone Support forAshwagandha
  33. Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists.
    Shenoy S; Chaskar U; Sandhu JS; Paadhi MM · Journal of Ayurveda and integrative medicine · 2013
    Randomized trial40 participantsFitness forAshwagandha
  34. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
    Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
    Randomized trial18 participantsFitness forRhodiola
  35. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsGeneral Health Sleep Support forAshwagandha
  36. Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
    Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
    Randomized trial150 participantsGeneral Health forAshwagandha
  37. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledGeneral Health Productivity Boost forAshwagandha
  38. Actaea racemosa L. Is More Effective in Combination with Rhodiola rosea L. for Relief of Menopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study.
    Pkhaladze L; Davidova N; Khomasuridze A; Shengelia R; Panossian AG · Pharmaceuticals (Basel, Switzerland) · 2024
    Randomized trial220 participantsGeneral Health forRhodiola
  39. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
    Randomized trialGeneral Health Productivity Boost forRhodiola
  40. [The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load].
    Spasov AA; Mandrikov VB; Mironova IA · Eksperimental'naia i klinicheskaia farmakologiia · 2000
    Clinical trialGeneral Health forRhodiola
  41. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  42. Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.
    Panossian A; Wagner H · Phytotherapy research : PTR · 2005
    Narrative reviewMental Focus forEleuthero
  43. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  44. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus Productivity Boost forRhodiola
  45. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  46. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  47. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  48. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  49. Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
    Urata M; Sakurai H; Ueno F; Maruki T; Tada T; Uchida T; Matsumoto Y; Murao M; Tomita M; Baba H; Kato M; Tsuboi T; Watanabe K · Neuropsychopharmacology reports · 2025
    Meta-analysis1,049 participants2 studies pooledMood Support forRhodiola
  50. The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
    Clinical trial10 participantsMood Support forRhodiola
  51. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.
    Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
    Systematic review66 studies pooledMood Support forRhodiola
  52. Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials.
    Moragrega I; Ríos JL · Planta medica · 2022
    Systematic reviewMood Support forRhodiola
  53. Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms.
    Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
    Single-arm trial118 participantsMood Support forRhodiola
  54. Ashwagandha Root Extract Stabilises Physiological Stress Responses in Male and Female Team Sports Athletes During Pre-Season Training.
    Coope OC; Otaegui E; Suárez M; Levington A; Abad-Sangrà M; Lloyd B; Spurr TJ; Roman-Viñas B · Nutrients · 2026
    Randomized trial56 participantsMuscle Gain forAshwagandha
  55. Evaluation of Withania somnifera (L.) Dunal (Ashwagandha) on Physical Performance, Biomarkers of Inflammation, and Muscle Status in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Study.
    Raut A; Tripathi R; Marathe PA; Uchil DA; Agashe S; Rege N; Vaidya AB · Cureus · 2024
    Randomized trialMuscle Gain forAshwagandha
  56. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
    Wankhede S; Langade D; Joshi K; Sinha SR; Bhattacharyya S · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial57 participantsMuscle Gain forAshwagandha
  57. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost Sleep Support forAshwagandha
  58. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  59. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
    Narrative reviewProductivity Boost Stress Relief forRhodiola
  60. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
  61. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
    Randomized trial60 participantsSleep Support forAshwagandha
  62. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  63. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  64. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  65. Stress management and the role of Rhodiola rosea: a review.
    Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
    Narrative reviewStress Relief forRhodiola
  66. Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
    Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
    Narrative reviewStress Relief forRhodiola
  67. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
    Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
    Randomized trial50 participantsTestosterone Support forAshwagandha
  68. Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
    Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
    Systematic review32 studies pooledTestosterone Support forAshwagandha
  69. Do "testosterone boosters" really increase serum total testosterone? A systematic review.
    Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
    Systematic review3 studies pooledTestosterone Support forAshwagandha
  70. Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
    Randomized trial40 participantsTestosterone Support forAshwagandha