Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
Randomized trial59 participantsflagBrain Health flagCognitive Support flagEnergy forscienceAshwagandha
- Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
Randomized trial40 participantsflagBrain Health flagCognitive Support flagMental Focus forscienceAshwagandha
- Efficacy of Withania somnifera supplementation on adult's cognition and mood.
Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
Randomized trial60 participantsflagBrain Health flagCognitive Support flagProductivity Boost forscienceAshwagandha
- A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
Randomized trial85 participantsflagBrain Health flagMental Focus forscienceAshwagandha
- Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
Randomized trial130 participantsflagBrain Health flagSleep Support flagStress Relief forscienceAshwagandha
- Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
Randomized trial27 participantsflagBrain Health flagFitness flagMental Focus forscienceRhodiola
- A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
Randomized trial100 participantsflagBrain Health forscienceRhodiola
- Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
Narrative reviewflagBrain Health forscienceRhodiola
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
Randomized trial56 participantsflagBrain Health flagGeneral Health flagProductivity Boost forscienceRhodiola
- Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
Single-arm trial50 participantsflagBrain Health flagCognitive Support forscienceRhodiola
- A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
Randomized trial54 participantsflagCognitive Support flagMental Focus forscienceAshwagandha
- Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
Randomized trial58 participantsflagCognitive Support flagMental Focus forscienceAshwagandha
- No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
Randomized trial144 participantsflagCognitive Support flagMental Focus flagProductivity Boost flagStress Relief forscienceEleuthero
- Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
Panossian A; Wikman G · Current clinical pharmacology · 2009
Narrative reviewflagCognitive Support flagMental Focus forscienceRhodiola flagEnergy flagMental Focus forscienceEleuthero
- Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
Clinical trial112 participantsflagCognitive Support forscienceRhodiola
- Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
Systematic review19 studies pooledflagCognitive Support flagStress Relief forscienceRhodiola
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
Randomized trial60 participantsflagCognitive Support flagProductivity Boost forscienceRhodiola
- Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
Randomized trial186 participantsflagEnergy flagMood Support forscienceAshwagandha
- Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
Randomized trialflagEnergy forscienceAshwagandha
- Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
Vittal M; Vinciguerra M · Biogerontology · 2025
Narrative reviewflagEnergy forscienceAshwagandha
- Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
Randomized trial120 participantsflagEnergy flagProductivity Boost forscienceAshwagandha
- Randomized controlled trial of Siberian ginseng for chronic fatigue.
Hartz AJ; Bentler S; Noyes R; Hoehns J; Logemann C; Sinift S; Butani Y; Wang W; Brake K; Ernst M; Kautzman H · Psychological medicine · 2004
Randomized trial96 participantsflagEnergy forscienceEleuthero
- The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human
J Kuo, K W Chen, I S Cheng, P H Tsai, Y J Lu, N Y Lee · Chinese Journal of Physiology · 2010
Randomized trial9 participantsflagEnergy forscienceEleuthero
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
Randomized trial48 participantsflagEnergy flagFitness forscienceRhodiola
- Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
Randomized trial24 participantsflagEnergy flagFitness flagMental Focus forscienceRhodiola
- Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
Randomized trial96 participantsflagEnergy forscienceRhodiola
- Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
Single-arm trial100 participantsflagEnergy flagGeneral Health flagStress Relief forscienceRhodiola
- Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
Randomized trial30 participantsflagEnergy flagFitness forscienceRhodiola
- Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial.
Ziegenfuss TN; Kedia AW; Sandrock JE; Raub BJ; Kerksick CM; Lopez HL · Nutrients · 2019
Randomized trial38 participantsflagFitness forscienceAshwagandha
- Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
Choudhary B; Shetty A; Langade DG · Ayu · 2016
Randomized trial50 participantsflagFitness flagGeneral Health forscienceAshwagandha
- Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
Randomized trial80 participantsflagFitness flagGeneral Health flagMuscle Gain forscienceAshwagandha
- Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
Meta-analysis1,249 participants20 studies pooledflagFitness flagMuscle Gain flagTestosterone Support forscienceAshwagandha
- Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists.
Shenoy S; Chaskar U; Sandhu JS; Paadhi MM · Journal of Ayurveda and integrative medicine · 2013
Randomized trial40 participantsflagFitness forscienceAshwagandha
- The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
Randomized trial18 participantsflagFitness forscienceRhodiola
- A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
Randomized trial150 participantsflagGeneral Health flagSleep Support forscienceAshwagandha
- Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
Randomized trial150 participantsflagGeneral Health forscienceAshwagandha
- Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
Meta-analysis400 participants5 studies pooledflagGeneral Health flagProductivity Boost forscienceAshwagandha
- Actaea racemosa L. Is More Effective in Combination with Rhodiola rosea L. for Relief of Menopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study.
Pkhaladze L; Davidova N; Khomasuridze A; Shengelia R; Panossian AG · Pharmaceuticals (Basel, Switzerland) · 2024
Randomized trial220 participantsflagGeneral Health forscienceRhodiola
- A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
Randomized trialflagGeneral Health flagProductivity Boost forscienceRhodiola
- [The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load].
Spasov AA; Mandrikov VB; Mironova IA · Eksperimental'naia i klinicheskaia farmakologiia · 2000
Clinical trialflagGeneral Health forscienceRhodiola
- Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
Randomized trial50 participantsflagMental Focus forscienceAshwagandha
- Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.
Panossian A; Wagner H · Phytotherapy research : PTR · 2005
Narrative reviewflagMental Focus forscienceEleuthero
- The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
Systematic review11 studies pooledflagMental Focus forscienceRhodiola
- Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
Randomized trial26 participantsflagMental Focus flagProductivity Boost forscienceRhodiola
- A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
Randomized trial141 participantsflagMood Support forscienceAshwagandha
- Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
Meta-analysis254 participants5 studies pooledflagMood Support forscienceAshwagandha
- A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
Randomized trial64 participantsflagMood Support flagStress Relief forscienceAshwagandha
- Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
Meta-analysis29 participants29 studies pooledflagMood Support forscienceAshwagandha
- Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
Urata M; Sakurai H; Ueno F; Maruki T; Tada T; Uchida T; Matsumoto Y; Murao M; Tomita M; Baba H; Kato M; Tsuboi T; Watanabe K · Neuropsychopharmacology reports · 2025
Meta-analysis1,049 participants2 studies pooledflagMood Support forscienceRhodiola
- The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
Clinical trial10 participantsflagMood Support forscienceRhodiola
- Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.
Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
Systematic review66 studies pooledflagMood Support forscienceRhodiola
- Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials.
Moragrega I; Ríos JL · Planta medica · 2022
Systematic reviewflagMood Support forscienceRhodiola
- Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms.
Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
Single-arm trial118 participantsflagMood Support forscienceRhodiola
- Ashwagandha Root Extract Stabilises Physiological Stress Responses in Male and Female Team Sports Athletes During Pre-Season Training.
Coope OC; Otaegui E; Suárez M; Levington A; Abad-Sangrà M; Lloyd B; Spurr TJ; Roman-Viñas B · Nutrients · 2026
Randomized trial56 participantsflagMuscle Gain forscienceAshwagandha
- Evaluation of Withania somnifera (L.) Dunal (Ashwagandha) on Physical Performance, Biomarkers of Inflammation, and Muscle Status in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Study.
Raut A; Tripathi R; Marathe PA; Uchil DA; Agashe S; Rege N; Vaidya AB · Cureus · 2024
Randomized trialflagMuscle Gain forscienceAshwagandha
- Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
Wankhede S; Langade D; Joshi K; Sinha SR; Bhattacharyya S · Journal of the International Society of Sports Nutrition · 2016
Randomized trial57 participantsflagMuscle Gain forscienceAshwagandha
- Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
Randomized trial80 participantsflagProductivity Boost flagSleep Support forscienceAshwagandha
- Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
Randomized trial20 participantsflagProductivity Boost forscienceAshwagandha
- The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
Narrative reviewflagProductivity Boost flagStress Relief forscienceRhodiola
- Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
Randomized trial135 participantsflagSleep Support forscienceAshwagandha
- Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
Randomized trial60 participantsflagSleep Support forscienceAshwagandha
- An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
Mishra DN; Kumar M · Heliyon · 2024
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Stress management and the role of Rhodiola rosea: a review.
Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
Narrative reviewflagStress Relief forscienceRhodiola
- Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
Narrative reviewflagStress Relief forscienceRhodiola
- Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
Randomized trial50 participantsflagTestosterone Support forscienceAshwagandha
- Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
Systematic review32 studies pooledflagTestosterone Support forscienceAshwagandha
- Do "testosterone boosters" really increase serum total testosterone? A systematic review.
Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
Systematic review3 studies pooledflagTestosterone Support forscienceAshwagandha
- Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
Randomized trial40 participantsflagTestosterone Support forscienceAshwagandha