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600 + D3 plus Minerals

21st Century
4.8
★ ★ ★ ★ ★
(1665 ratings)
Calcium 600 mg
Copper 1 mg
Product Image
Score83
A very economical one-tablet calcium and D3 formula with useful cofactors. Basic carbonate and oxide forms are the main compromise.
How scoring works
Quantity:120 Tablet(s) • (120 servings)
Goals:
Bone Health

Score 83

A very economical one-tablet calcium and D3 formula with useful cofactors. Basic carbonate and oxide forms are the main compromise.
How scoring works

Also available as

1 option
600.00mg Calcium, 40.00mg Magnesium • 75 servings • Fruit Punch Copper 1 mg, Calcium 600 mg • 75 Tablet(s) • 75 servings $8.49 ($0.11 per serving)
$5.49($0.04 per serving)
iHerb
$ 5.49
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Analysis

The one-tablet serving combines 600 mg calcium with vitamin D3, magnesium, zinc, copper, manganese, and boron. The calcium amount is well suited to filling a daily gap without exceeding an efficient single dose.

Calcium carbonate works best with food, and oxide forms for magnesium, zinc, and copper are less favorable than citrate or chelated alternatives. Magnesium and boron are too low for comprehensive mineral support.

The formula suits users who prioritize price and convenience over premium forms. People with low stomach acid or a meaningful magnesium need should consider a different product.

Who is it for
  • Adults seeking low-cost calcium and D3
  • People who tolerate calcium carbonate
  • Users wanting a simple one-tablet routine
Best for
  • Filling a calcium gap
  • Basic bone support
  • Budget-focused mineral supplementation

Pros

  • Provides 600 mg calcium
  • Includes 20 mcg vitamin D3
  • Adds zinc, copper, manganese, and boron
  • One-tablet serving
  • Excellent value

Cons

  • Uses calcium carbonate
  • Magnesium, zinc, and copper are oxide forms
  • Magnesium amount is small
  • Boron amount is modest
  • Best taken with food

Warnings

  • Calcium can reduce absorption of levothyroxine, bisphosphonates, and tetracycline-class antibiotics when taken together, so doses need separation.
  • People with kidney disease or a history of calcium-containing kidney stones should review high-dose calcium and vitamin D use clinically.
  • Calcium carbonate may cause constipation, gas, or bloating in sensitive users.

Nutrient quality

80 High impact

Vitamin D3 is favorable, but calcium carbonate and the oxide minerals have weaker absorption. Calcium and vitamin D3 are useful, while magnesium and boron remain small additions.

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Ingredient transparency

81 Highest impact

Every listed active nutrient has a specific amount. The supplied data does not include a complete inactive ingredient list.

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Customer satisfaction

73 High impact

The aggregate satisfaction measure and review volume support a favorable first impression. Missing firsthand feedback leaves repeat complaints and real-world purpose fit uncertain.

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Value for money

96 Highest impact

The exceptionally low product cost is appropriate for a straightforward bone formula. Each serving provides excellent value for calcium and vitamin D3.

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Goals

Bone Health
Bone Health
Impact
Highest effect
A Goal FitB- Strength of SupportB+ CoverageA- Formula Quality
Magnesium · 50 mgCalcium · 600 mgVitamin D · 20 mcgCopper · 1 mgManganese · 1.8 mgBoron · 250 mcgZinc · 7.5 mg

Calcium and vitamin D3 anchor a broad bone-support formula. Magnesium, zinc, copper, manganese, and boron add mineralization and matrix-related support.

Several secondary minerals are modest and use less absorbable oxide forms. The main calcium dose is practical, making the formula useful despite uneven form quality.

Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Copper Disputed 20 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Zinc Supportive 33 studies

Ingredients

IngredientAmount per serving
Vitamin D3 (Cholecalciferol)
 20 mcg
Calcium (Calcium Carbonate)
 600 mg
Magnesium (Magnesium Oxide)
 50 mg
Zinc (Zinc Oxide)
 7.5 mg
Copper (Copper Oxide)
 1 mg
Manganese (Manganese Sulfate)
 1.8 mg
Boron (Sodium Borate)
 250 mcg
Gluten Free Adults 18–50
Report overview
Calcium (Calcium Carbonate) · 600 mg OverallScore86
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The 600 mg calcium carbonate dose fits the efficient single-serving range, but the form works best with food. Vitamin D3 and several trace minerals broaden the formula without listed controversial additives. The cost per serving is very low for the amount provided.

View ingredientView products
Copper (Copper Oxide) · 1 mg OverallScore63
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value

Copper oxide is clearly disclosed but has very poor bioavailability. The 1 mg dose supports routine maintenance without approaching excessive intake. The very low serving cost makes the formula highly economical for copper delivery.

View ingredientView products
Loading alternative details
88 Performance

Calcium Hydroxyapatite Caps

NOW
Hydroxyapatite supplies calcium with phosphorus in a form that closely reflects bone mineral. The clear, focused design improves form quality over calcium carbonate and oxide minerals, although vitamin D3 and copper are absent.
85 Performance

Cal/Mag 500 mg/250 mg

NaturesPlus
Chelated calcium and magnesium replace the original’s carbonate and oxide forms with a balanced mineral pairing. The formula omits vitamin D3 and copper but offers stronger form quality and a simple serving.
83 Performance

Albion Chelated Calcium 180 mg

Swanson Ultra
Calcium glycinate chelate provides a more flexible, clearly identified form with a small vitamin D3 addition. The calcium amount is lower than the original and the supplied label details conflict with the product name, so verification is prudent.
84 Budget

600 Calcium Supplement

21st Century
A still-lower serving cost provides a similarly sized calcium carbonate amount in a simpler tablet. Vitamin D3 and trace minerals are omitted, so the savings come with narrower bone-support coverage.
85 Budget

Copper 2 mg

Swanson
A lower recurring cost provides focused copper in a chelated form rather than copper oxide. Calcium and vitamin D3 are absent, so it only replaces the copper portion of the original formula.
85 Budget

Calcium Carbonate

NOW
Only two eligible candidates with distinct brands are strictly cheaper, and this simple powder is the closest equal-cost calcium option. It supplies substantial calcium without vitamin D3 or supporting minerals, while carbonate should be taken with food.
85 Value

600+D3

21st Century
The same calcium carbonate and vitamin D3 pairing comes at a lower serving cost with a simpler label. Supporting magnesium, zinc, copper, manganese, and boron are absent, but the core bone-support ingredients remain.
83 Value

Citracal Petites Calcium Citrate +D3

Bayer Citracal
A compact serving combines calcium and vitamin D3 at a modest recurring cost. The supplied ingredients do not confirm the citrate form named on the product, yet the long supply and focused profile still provide reasonable value.
84 Value

Calcium 600 with Vitamin D3

Nature's Bounty
The main calcium-and-vitamin-D3 combination is preserved in a focused, low-cost tablet. Magnesium and trace minerals are missing, and calcium carbonate works best with food, but unnecessary extras are avoided.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
    Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
    Meta-analysis1,566 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation and bone mineral density in postmenopausal women using estrogen replacement therapy.
    Haines CJ; Chung TK; Leung PC; Hsu SY; Leung DH · Bone · 1995
    Randomized trialBone Health forCalcium
  3. Bone turnover and the response to alendronate treatment in postmenopausal osteoporosis.
    Gonnelli S; Cepollaro C; Pondrelli C; Martini S; Montagnani A; Monaco R; Gennari C · Calcified tissue international · 1999
    Randomized trial100 participantsBone Health forCalcium
  4. Associations of dietary calcium intake with metabolic syndrome and bone mineral density among the Korean population: KNHANES 2008-2011.
    Kim MK; Chon SJ; Noe EB; Roh YH; Yun BH; Cho S; Choi YS; Lee BS; Seo SK · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Cross-sectional study14,705 participantsBone Health forCalcium
  5. Treatment with alendronate plus calcium, alendronate alone, or calcium alone for postmenopausal low bone mineral density.
    Bonnick S; Broy S; Kaiser F; Teutsch C; Rosenberg E; DeLucca P; Melton M · Current medical research and opinion · 2007
    Randomized trial701 participantsBone Health forCalcium
  6. Calcium and osteoporosis.
    Nordin BE · Nutrition (Burbank, Los Angeles County, Calif.) · 1998
    Meta-analysis20 studies pooledBone Health forCalcium
  7. Dietary calcium intake protects women consuming oral contraceptives from spine and hip bone loss.
    Teegarden D; Legowski P; Gunther CW; McCabe GP; Peacock M; Lyle RM · The Journal of clinical endocrinology and metabolism · 2005
    Randomized trial154 participantsBone Health forCalcium
  8. Relationship between bone mineral density changes and risk of fractures among patients receiving calcium with or without vitamin D supplementation: a meta-regression.
    Rabenda V; Bruyère O; Reginster JY · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011
    Meta-analysis47,365 participants15 studies pooledBone Health forCalcium
  9. Calcium supplementation provides an extended window of opportunity for bone mass accretion after menarche.
    Rozen GS; Rennert G; Dodiuk-Gad RP; Rennert HS; Ish-Shalom N; Diab G; Raz B; Ish-Shalom S · The American journal of clinical nutrition · 2003
    Randomized trial100 participantsBone Health forCalcium
  10. Effect of milk and calcium supplementation on bone density and bone turnover in pregnant Chinese women: a randomized controlled trail.
    Liu Z; Qiu L; Chen YM; Su YX · Archives of gynecology and obstetrics · 2011
    Randomized trial36 participantsBone Health forCalcium
  11. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  12. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  13. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  14. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  15. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  16. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  17. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  18. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  19. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  20. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  21. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  22. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  23. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  24. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  25. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  26. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  27. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  28. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  29. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  30. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  31. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  32. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  33. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  34. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  35. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  36. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  37. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  38. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  39. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  40. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc