BioCoenzymated Pantethine 450 mg
Natural Factors
BioCoenzymated Pantethine 450 mg
4.9
★ ★ ★ ★ ★
(1659 ratings)
Vitamin B5 450 mg
Score 85.0
A high-potency, potentially more bioavailable Pantethine supplement from a reputable brand, ideal for targeted support, though at a higher price point.
Quantity: 60 Softgel(s)Servings size: 1 Softgel(s) (60 servings)
Selected goals:
Other goals:
Skin Health
Stress Relief
Energy
leaderboard Score 85.0
A high-potency, potentially more bioavailable Pantethine supplement from a reputable brand, ideal for targeted support, though at a higher price point.
Dose: 300mg, Quantity: 60Dose: 600mg, Quantity: 60Dose: 300mg, Quantity: 60Dose: 450mg, Quantity: 60Dose: 300mg, Quantity: 90Dose: 250mg, Quantity: 60
insights Analysis
Natural Factors' BioCoenzymated Pantethine provides a robust dose of 450mg per capsule, making it a potent option for individuals specifically targeting the benefits of Pantethine. The 'BioCoenzymated' designation suggests a form designed for improved bioavailability, which could translate to more effective support for metabolic pathways involved in energy production, stress response, and skin health. This product is well-regarded by users, as evidenced by its high review count, affirming its perceived effectiveness and consumer trust.
- Highest dose of Pantethine (450mg) among the analyzed products for maximum potency.
- 'BioCoenzymated' form implies enhanced absorption and efficacy.
- Strong brand reputation with a high review count, indicating consumer trust and satisfaction.
- Higher price per serving compared to many alternatives and some other Pantethine options, potentially limiting affordability for some users.
$23.61($0.39 per serving)
 iHerb | $ 23.61 | |
 Amazon | $ 27.97 |
bolt Effectiveness for goals
Vitamin B5, also known as pantothenic acid, is essential for converting food into energy. It plays a crucial role in the synthesis of fatty acids, hormones, and neurotransmitters. This vitamin supports various metabolic processes vital for overall health.
Yes, Vitamin B5 is a key component of coenzyme A (CoA), which is vital for many metabolic reactions. These reactions include the breakdown of carbohydrates, fats, and proteins, facilitating energy release. It is crucial for cellular energy metabolism.
People commonly take Vitamin B5 supplements to support energy production, skin health, and overall metabolic function. It is often included in B-complex supplements for its broad role in the body. Some individuals also consider it for hair health or stress support.
Some studies suggest that pantothenic acid may help manage acne, possibly by regulating sebum production. However, more robust scientific evidence from large-scale human trials is needed to confirm these specific effects. It is often included in skincare formulations.
Pantothenic acid is a common ingredient in hair care products, often included for its role in cellular growth and repair. While essential for healthy hair, direct evidence of supplements significantly promoting hair growth in non-deficient individuals is limited. It primarily supports the health of existing hair follicles.
schedule Dosage, timing & forms
The recommended daily intake of pantothenic acid for adults is typically 5 milligrams (mg). This amount is generally sufficient to meet the nutritional needs of most healthy individuals. Higher amounts may be found in some supplements.
Vitamin B5 is most commonly found in supplements as calcium pantothenate or D-pantothenic acid. Another common form is pantethine, which is a derivative of pantothenic acid. These forms are generally well-absorbed by the body.
There is no established Tolerable Upper Intake Level (UL) for Vitamin B5 (pantothenic acid) due to its low toxicity. Even at very high doses, it is generally considered safe. However, extremely high intakes might lead to mild digestive upset.
Vitamin B5 supplements, particularly B-complex vitamins, are generally recommended to be taken with food. This can help improve absorption and minimize potential stomach upset. Taking it with a meal ensures better tolerance.
Pantethine is a derivative of pantothenic acid and is often used for its potential role in lipid metabolism. Dosages of pantethine are typically higher than the basic pantothenic acid recommendations, often ranging from 300 mg to 900 mg per day. The specific dosage depends on the intended use and should be guided by product instructions.
health_and_safety Safety & interactions
There is no established Upper Intake Level (UL) for Vitamin B5 due to its low toxicity. Extremely high doses, far exceeding typical supplement amounts, may lead to mild intestinal disturbances like diarrhea. Toxicity is generally not a concern with standard supplementation.
Vitamin B5 (pantothenic acid) is generally well-tolerated. At very high doses, some individuals might experience mild gastrointestinal upset or diarrhea. Serious adverse effects are rare.
Vitamin B5 generally has few significant interactions with medications. However, very high doses might theoretically interfere with the absorption or action of certain antibiotics, like tetracyclines, if taken simultaneously. It is advisable to consult a healthcare professional regarding potential interactions.
Vitamin B5 is an essential nutrient and generally considered safe when taken at recommended daily allowance levels during pregnancy and breastfeeding. Excessive supplementation beyond nutritional needs should be discussed with a healthcare provider. Always consult a healthcare professional for personalized advice.
Long-term supplementation with Vitamin B5 at recommended or moderately higher doses is generally considered safe for healthy individuals. Due to its water-soluble nature, excess amounts are typically excreted by the body. Always adhere to recommended dosages unless advised otherwise by a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Pantethine | 450 mg |
Categories
Vitamin B5 90.0
This product delivers a substantial 450mg dose of Pantethine, a highly bioavailable and effective form of Vitamin B5, directly supporting the core benefits associated with this essential vitamin.
Goals
Energy 90.0
Pantethine is a direct precursor to Coenzyme A, a fundamental molecule in the body's energy production cycle (Krebs cycle). Adequate levels can significantly enhance cellular energy metabolism, leading to improved overall energy levels.
Skin Health 85.0
Pantethine, as a derivative of Vitamin B5, plays a crucial role in cellular metabolism and maintaining healthy skin barriers. Its contribution to Coenzyme A synthesis aids in fatty acid metabolism, which is essential for skin repair and combating issues like excessive oil production.
Stress Relief 85.0
B vitamins, including Pantethine, are vital for adrenal gland function and the synthesis of neurotransmitters, supporting the body's natural response to stress and contributing to a calmer physiological state.
Recommended Alternatives
95 Value 
Pantothenic Acid 500 mg
Solaray
4.7
★★★★★
(3906 ratings)
Offering a higher dose of B5 (500mg) at a significantly lower price per serving ($0.11) compared to the original Pantethine product ($0.46 for 450mg), this provides exceptional value for potent B5 support.
93 Value 
Super Stress B-Complex with Vitamin C
Swanson
4.7
★★★★★
(2248 ratings)
This B-complex is a fantastic value, delivering 125mg of Pantothenic Acid and other stress-supporting B vitamins and Vitamin C at an incredibly low price of $0.08 per serving, making it highly cost-effective for comprehensive B vitamin needs.
90 Value 
B-50
NOW
4.7
★★★★★
(3542 ratings)
As a cost-effective B-complex ($0.10/serving) from a highly reputable brand, this product offers 50mg of Pantothenic Acid alongside a balanced blend of other B vitamins, providing excellent overall support for energy and stress for its price.
92 Performance 
Pantothenic Acid 1000 mg
KAL
4.7
★★★★★
(834 ratings)
While a different form, this product offers a massive 1000mg dose of Pantothenic Acid, far surpassing the B5 content of the original product, which could lead to more pronounced effects for certain individuals aiming for high potency B5.
90 Performance 
Advanced Nutrients
Thorne
4.6
★★★★★
(851 ratings)
Although more expensive, Thorne is renowned for quality. This multi-nutrient formula contains 450mg of Pantothenic Acid and a comprehensive blend of nutrients that synergistically support overall energy, stress response, and skin health beyond just Pantethine.
88 Performance 
Life Extension Mix Capsules
Life Extension
4.7
★★★★★
(492 ratings)
This highly comprehensive multivitamin includes a substantial 600mg of Pantothenic Acid, providing a broader spectrum of nutrients that synergistically support overall energy, stress resilience, and skin health, making it a more holistic choice.
90 Budget 
Pantothenic Acid 100 mg
Source Naturals
4.7
★★★★★
(652 ratings)
At $0.05 per serving, this is significantly cheaper than the analyzed product ($0.46) while still providing a good foundational dose of Vitamin B5 (Pantothenic Acid) for similar goals, making it an excellent budget-friendly entry point.
88 Budget 
Super Stress B-Complex with Vitamin C
Swanson
4.7
★★★★★
(1820 ratings)
Priced at $0.08 per serving, this B-complex offers a broader spectrum of B vitamins including 125mg of Pantothenic Acid, plus Vitamin C, providing comprehensive support for stress and energy at a fraction of the cost.
85 Budget 
B-50
NOW
4.7
★★★★★
(30076 ratings)
With a price of $0.10 per serving, this well-regarded B-complex provides 50mg of Pantothenic Acid alongside other essential B vitamins, offering balanced nutritional support for energy and stress at a much lower cost.
95 Value
Pantothenic Acid 500 mg
Solaray
4.7
★★★★★
(3906 ratings)
Offering a higher dose of B5 (500mg) at a significantly lower price per serving ($0.11) compared to the original Pantethine product ($0.46 for 450mg), this provides exceptional value for potent B5 support.
93 Value
Super Stress B-Complex with Vitamin C
Swanson
4.7
★★★★★
(2248 ratings)
This B-complex is a fantastic value, delivering 125mg of Pantothenic Acid and other stress-supporting B vitamins and Vitamin C at an incredibly low price of $0.08 per serving, making it highly cost-effective for comprehensive B vitamin needs.
90 Value
B-50
NOW
4.7
★★★★★
(3542 ratings)
As a cost-effective B-complex ($0.10/serving) from a highly reputable brand, this product offers 50mg of Pantothenic Acid alongside a balanced blend of other B vitamins, providing excellent overall support for energy and stress for its price.
92 Performance
Pantothenic Acid 1000 mg
KAL
4.7
★★★★★
(834 ratings)
While a different form, this product offers a massive 1000mg dose of Pantothenic Acid, far surpassing the B5 content of the original product, which could lead to more pronounced effects for certain individuals aiming for high potency B5.
90 Performance
Advanced Nutrients
Thorne
4.6
★★★★★
(851 ratings)
Although more expensive, Thorne is renowned for quality. This multi-nutrient formula contains 450mg of Pantothenic Acid and a comprehensive blend of nutrients that synergistically support overall energy, stress response, and skin health beyond just Pantethine.
88 Performance
Life Extension Mix Capsules
Life Extension
4.7
★★★★★
(492 ratings)
This highly comprehensive multivitamin includes a substantial 600mg of Pantothenic Acid, providing a broader spectrum of nutrients that synergistically support overall energy, stress resilience, and skin health, making it a more holistic choice.