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Resveratrol 250 mg

Swanson Ultra
4.7
★ ★ ★ ★ ★
(487 ratings)
Resveratrol 250 mg
Product Image
Score65
A simple knotweed-derived capsule has a practical listed amount, but unconfirmed trans yield and refinement make potency uncertain.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:

Score 65

A simple knotweed-derived capsule has a practical listed amount, but unconfirmed trans yield and refinement make potency uncertain.
How scoring works
$25.19($0.83 per serving)
iHerb
$ 25.19
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Analysis

The one-capsule formula supplies 250 mg resveratrol from Polygonum cuspidatum root. Its simple design avoids unrelated blend ingredients.

The listed amount appears to describe the source extract rather than a confirmed trans-resveratrol yield. Purity and removal of laxative anthraquinones are not reported.

Routine cost is moderate for a focused capsule. Better-characterized products disclose the trans amount directly and verify source refinement.

Who is it for
  • Adults seeking a basic knotweed resveratrol capsule
  • People comfortable with unverified trans yield
  • Users preferring a single ingredient
Best for
  • Simple daily supplementation
  • Users avoiding complex blends
  • General resveratrol intake

Pros

  • Focused one-ingredient design
  • Names the knotweed root source
  • Convenient capsule
  • Clear total extract amount

Cons

  • Trans-resveratrol yield is not confirmed
  • Purity is unstated
  • Emodin removal is unverified
  • No enhanced delivery

Warnings

  • Residual knotweed emodin may cause loose stools
  • Resveratrol may increase bleeding tendency with blood-thinning medicines

Nutrient quality

63 Moderate impact

A basic knotweed extract does not confirm the preferred trans isomer, purity, or enhanced delivery. The extract weight is substantial, but the active trans-resveratrol dose cannot be determined.

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Ingredient transparency

76 High impact

Every listed active ingredient has a specific amount. Usage and inactive-ingredient details remain incomplete.

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Customer satisfaction

68 High impact

The average rating is consistently strong. The substantial feedback pool makes the average reasonably dependable.

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Value for money

47 Lower impact

The price lacks support from a verified active amount. Serving value cannot be established without trans-resveratrol yield.

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Goals

Cardiovascular Support
Impact
Moderate effect
C+ Goal FitD+ Strength of SupportD- CoverageA+ Formula Quality

Resveratrol may support endothelial signaling and antioxidant protection. The knotweed extract weight appears substantial if it represents active trans-resveratrol.

Trans-isomer yield, purity, and emodin removal are not disclosed. Mixed human results and incomplete active-dose information make this a speculative cardiovascular option.

Study evidence
Resveratrol Supportive 73 studies
Anti-Inflammatory Support
Impact
Moderate effect
C+ Goal FitC- Strength of SupportF CoverageA+ Formula Quality

Knotweed-derived resveratrol may influence inflammatory signaling and cellular stress pathways. The stated extract amount looks substantial, but the active trans-resveratrol yield is unknown.

Single-ingredient focus keeps the formula simple and free from padding. Missing isomer, purity, and emodin information prevents a reliable assessment of dose and form quality.

Study evidence
Resveratrol Supportive 34 studies
Skin Health
Impact
Moderate effect
C+ Goal FitD Strength of SupportD- CoverageB- Formula Quality
Resveratrol · 250 mg

Resveratrol provides a plausible antioxidant route to supporting skin resilience. Confidence is limited because the label states only knotweed extract and does not confirm active trans-resveratrol yield.

The single-ingredient design is focused but covers no structural or hydration pathway. Missing isomer, purity, and emodin-removal details make the effective contribution uncertain.

Study evidence
Resveratrol Supportive 7 studies
Anti-Aging
Impact
Moderate effect
C Goal FitD- Strength of SupportD- CoverageB+ Formula Quality

Resveratrol is relevant to oxidative and metabolic pathways associated with healthy aging. The extract amount looks substantial, but the label does not confirm how much active trans-resveratrol it provides.

Unclear isomer content, purity, and emodin removal make the effective dose and evidence fit difficult to judge. The streamlined formula avoids padding but offers only narrow pathway coverage.

Study evidence
Resveratrol No effect 7 studies
Metabolism Boost
Impact
Moderate effect
D+ Goal FitD- Strength of SupportD- CoverageA Formula Quality
Resveratrol · 250 mg

Resveratrol may influence mitochondrial signaling and insulin sensitivity, but human metabolic results are inconsistent. The listed knotweed extract amount cannot be treated as confirmed active resveratrol.

The label omits trans-isomer content, active yield, purity, and emodin-removal details. Those gaps make both effective dose and tolerability harder to judge despite the focused design.

Study evidence
Resveratrol Supportive 21 studies

Ingredients

IngredientAmount per serving
Resveratrol (Polygonum cuspidatum root extract)
250 mg
Adults 18–50
Report overview
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

A substantial knotweed extract amount could be useful if it represents active trans-resveratrol. The label does not confirm the trans-isomer, active yield, purity percentage, or emodin removal. Standard capsule delivery and unquantifiable active-dose cost leave important uncertainty.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
    Witte AV; Kerti L; Margulies DS; Flöel A · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Randomized trial46 participantsAnti-Aging forResveratrol
  2. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsAnti-Aging forResveratrol
  3. Resveratrol levels and all-cause mortality in older community-dwelling adults.
    Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C · JAMA internal medicine · 2014
    Cohort study783 participantsAnti-Aging forResveratrol
  4. Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
    Mansouri F; Feliziani G; Bordoni L; Gabbianelli R · Journal of the Academy of Nutrition and Dietetics · 2025
    Meta-analysis11 studies pooledAnti-Aging forResveratrol
  5. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.
    Rao A; Briskey D; Roche G; Tremblay A; Da Silva Pinto M; Tompkins TA · Frontiers in aging · 2026
    Randomized trial134 participantsAnti-Aging Skin Health forResveratrol
  6. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  7. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  8. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  9. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsAnti-Inflammatory Support forResveratrol
  10. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  11. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; García-Almagro FJ; Avilés-Plaza F; Parra S; Yáñez-Gascón MJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · Molecular nutrition & food research · 2012
    Randomized trial75 participantsCardiovascular Support forResveratrol
  12. Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.
    Ahmadi P; Akbarzadeh S; Alizadeh M; Mohammadi N; Mahmoodi M; Amini A; Netticadan T; Rezaei M; Movahed A · Molecular and cellular biochemistry · 2025
    Randomized trial60 participantsCardiovascular Support forResveratrol
  13. Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases.
    Shen CY; Li CP; Yu JT; Ho YJ; Tsai RY · In vivo (Athens, Greece) · 2026
    Meta-analysis2,551 participants40 studies pooledCardiovascular Support forResveratrol
  14. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
    Wong RH; Berry NM; Coates AM; Buckley JD; Bryan J; Kunz I; Howe PR · Journal of hypertension · 2014
    Randomized trial28 participantsCardiovascular Support forResveratrol
  15. Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind, placebo-controlled trial.
    Simental-Mendía LE; Guerrero-Romero F · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Randomized trial71 participantsCardiovascular Support forResveratrol
  16. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.
    Zhu X; Wu C; Qiu S; Yuan X; Li L · Nutrition & metabolism · 2022
    Meta-analysis283 participants9 studies pooledMetabolism Boost forResveratrol
  17. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
    Sun JN; Yang R; Fang L; Li YJ; Xing WY; Sun ML; Wu L; Wu QJ; Gong TT · Nutrition journal · 2026
    Meta-analysis45 studies pooledMetabolism Boost forResveratrol
  18. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
    Chen S; Zhao X; Ran L; Wan J; Wang X; Qin Y; Shu F; Gao Y; Yuan L; Zhang Q; Mi M · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015
    Randomized trial60 participantsMetabolism Boost forResveratrol
  19. Supplementation with resveratrol modified gut microbiota improving insulin sensitivity and lipid metabolism in subjects with obesity and insulin resistance.
    Guevara-Cruz M; Sánchez-Tapia M; Velazquez-Villegas LA; Torre-Villalvazo I; Guizar-Heredia R; Godínez-Salas E; López-Barradas A; Granados O; Torres-Villalobos G; Torres N; Tovar AR · European journal of nutrition · 2026
    Randomized trial32 participantsMetabolism Boost forResveratrol
  20. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
    Zhou Q; Wang Y; Han X; Fu S; Zhu C; Chen Q · Frontiers in physiology · 2022
    Meta-analysis1,171 participants25 studies pooledMetabolism Boost forResveratrol
  21. Efficacy and safety of Resveratrol combined with Ablative Fractional CO2 laser system in the treatment of skin photoaging.
    Du YM; Zeng J; Li M; Wang YB; Wu Y; Qi RQ; Gao XH; Chen HD · Journal of cosmetic dermatology · 2021
    Non-randomized trial32 participantsSkin Health forResveratrol
  22. Exploring resveratrol-enriched collagen dressings for diabetic foot ulcers: A retrospective study of wound healing outcomes.
    Sezikli İ; Kendirci M · Journal of tissue viability · 2025
    Cohort study41 participantsSkin Health forResveratrol
  23. Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
    Moyano-Mendez JR; Fabbrocini G; De Stefano D; Mazzella C; Mayol L; Scognamiglio I; Carnuccio R; Ayala F; La Rotonda MI; De Rosa G · Drug development and industrial pharmacy · 2016
    Clinical trialSkin Health forResveratrol
  24. Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.
    Montenegro L; Parenti C; Turnaturi R; Pasquinucci L · Pharmaceutics · 2020
    Clinical trial12 participantsSkin Health forResveratrol