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SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
5.0
★ ★ ★ ★ ★
(11 ratings)
SAMe 200 mg
Folate 100 mcg
Vitamin B12 50 mcg
Vitamin B6 5 mg
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Score 88

A well-formulated supplement combining SAMe with active forms of B6, B12, and Folate, designed for targeted mood, cognitive, and general methylation support.

Quantity: 30 Capsule(s) • (30 servings)
Goals:
flag Joint Health
flag Mood Support
flag Detoxification
flag Stress Relief
flag Cognitive Support

leaderboard Score 88

A well-formulated supplement combining SAMe with active forms of B6, B12, and Folate, designed for targeted mood, cognitive, and general methylation support.

insightsAnalysis

This supplement features SAMe, an important compound often used for mood and cognitive support. What sets it apart is the thoughtful inclusion of key B vitamins in their active forms: Vitamin B-6 as Pyridoxal 5-Phosphate, Vitamin B12 as Methylcobalamin, and Folate as 5-Methyltetrahydrofolate (MTHF).

These active B vitamins can contribute to more efficient utilization in the body, which is particularly beneficial for individuals whose bodies may not readily convert standard B vitamin forms. The synergistic blend of SAMe with these active B vitamins is designed to support methylation, a fundamental process involved in many bodily functions including mood regulation and neurological health.

While the price per serving might be on the higher side, it reflects the quality of the ingredients, especially SAMe and the more bioavailable forms of B vitamins. It's a focused formula for those looking for specific support in these areas rather than a broad-spectrum daily multivitamin.

thumb_upPros
  • Contains SAMe, which is often used for mood and cognitive well-being.
  • Features active forms of Vitamin B-6 (P-5-P), Vitamin B12 (Methylcobalamin), and Folate (5-MTHF).
  • The combination of ingredients supports the body's methylation processes.
  • Convenient capsule form for daily intake.
thumb_downCons
  • Higher price per serving compared to basic B vitamin supplements.
  • Low review count makes it harder to gauge widespread customer experiences.
warningWarnings
  • SAMe can interact with certain medications; consulting a healthcare professional is advisable before use.
  • Some individuals may experience mild digestive upset when first taking SAMe.
  • Keep out of reach of children.
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$58.99($1.96 per serving)
Pure Formulas
$ 58.99
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Ingredients

IngredientAmount per serving
Vitamin B-6
5 mg
Folate
100 mcg
Vitamin B12
50 mcg
SAMe
200 mg
grain_off Gluten Free person Adults 18–50
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Categories

Vitamin B12 95
This product uses Methylcobalamin, which is an active and generally well-absorbed form of Vitamin B12. This choice of form is excellent for supporting neurological function and energy metabolism.
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Vitamin B6 95
The inclusion of Pyridoxal 5-Phosphate (P-5-P) as the form of Vitamin B6 is a high-quality choice. P-5-P is the active coenzyme form, making it readily available for the body's use in various enzymatic reactions.
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Folate 95
Featuring 5-Methyltetrahydrofolate (5-MTHF) as Folate, particularly in its Glucosamine Salt form, represents a superior choice over synthetic folic acid. This active form is highly bioavailable and directly usable by the body for methylation and cell division.
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Goals

flag Mood Support 92
SAMe is often used for its potential role in supporting balanced mood. The active B vitamins in this formula are also important cofactors in pathways that influence mood regulation, making this a strong option for mood support.
flag Cognitive Support 90
SAMe, along with active forms of B6, B12, and Folate, can contribute significantly to brain health and neurotransmitter synthesis. These ingredients may help support clear thinking and memory function.
flag Brain Health 90
The combination of SAMe and active B vitamins is directly relevant to brain health through supporting neurotransmitter production and methylation. This can contribute to overall neurological function and maintenance.
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