SuppHelper
search
Home›Supplements›Other›SAMe›SAMe 400 mg Life Extension
Product Image

SAMe 400 mg

Life Extension
4.8
★ ★ ★ ★ ★
(3546 ratings)
SAMe 400 mg
Product Image
Score 85

A very popular and affordable 400mg SAMe tablet from a respected brand, with excellent customer feedback, but without specific SAMe form details.

Quantity: 60 Tablet(s) • (60 servings)
Goals:
flag Joint Health
flag Mood Support
flag Detoxification
flag Stress Relief

leaderboard Score 85

A very popular and affordable 400mg SAMe tablet from a respected brand, with excellent customer feedback, but without specific SAMe form details.

Quantity: 30Dose: 200mg, Quantity: 30

insightsAnalysis

Life Extension provides a robust 400mg dose of S-Adenosyl-Methionine in tablet form, which is a significant potency for supporting various health goals. The price per serving of $0.62 is excellent for a 400mg product, especially considering it comes in a convenient 60-count bottle for extended use.

The product boasts an exceptionally high number of positive customer reviews (over 3,500), indicating strong trust and widespread satisfaction. While the ingredient list names "S-Adenosyl-Methionine" without specifying a stable form like tosylate disulfate, the brand's reputation and extensive feedback suggest a reliable product.

thumb_upPros
  • Provides a substantial 400mg dose of SAMe per tablet
  • Excellent price per serving ($0.62) for this higher potency
  • Generous 60-count bottle offers a convenient, longer supply
  • Exceptionally high number of positive customer reviews (3546) indicates widespread satisfaction
  • Comes from a highly respected and research-focused brand, Life Extension
thumb_downCons
  • Specific stable form of SAMe (e.g., tosylate disulfate) is not explicitly listed
  • Tablet form might not be ideal for splitting if smaller, precise doses are desired
  • No additional synergistic cofactors are included
warningWarnings
  • Individuals new to SAMe or sensitive to higher doses should consider a gradual introduction.
  • Consult a professional before use, especially if on medications affecting mood, such as antidepressants, or if you have bipolar disorder.
flagReport analysis
$37.49($0.62 per serving)
Amazon
$ 37.49
iHerb
$ 49.50
flagReport prices

Ingredients

IngredientAmount per serving
S-Adenosyl-Methionine
400 mg
person Adults 18–50
flagReport overview

Categories

SAMe 85
<p>This product is a strong contender in the SAMe collection due to its high dose, excellent price point, and widespread customer acceptance, making it a reliable and accessible option.</p>
storefront View products

Goals

flag Joint Health 85
<p>The robust 400mg dose of SAMe is well-suited for comprehensive support of joint cartilage and overall comfort, making it a strong option for joint health.</p>
flag Mood Support 85
<p>This 400mg potency of SAMe can significantly contribute to maintaining balanced neurotransmitter levels, which is important for supporting a healthy and stable mood.</p>
flag Detoxification 85
<p>As a powerful methyl donor, this 400mg dose of SAMe offers robust support for vital methylation pathways involved in the body's natural detoxification processes.</p>
inventory_2Recommended products
96 Value

SAMe 400 mg

Nutricost
4.6
★★★★★
(980 ratings)
Offers an outstanding value for 400mg SAMe at $0.59 per serving, providing superior cost-effectiveness while maintaining a high dose.
Other sellers (1)
95 Value

SAMe 400 mg

NOW
4.6
★★★★★
(1853 ratings)
This alternative delivers 400mg SAMe at $0.68 per serving, offering excellent value from a highly trusted brand, balancing high quality with affordability.
Other sellers (4)
98 Value

SAMe 400 mg

Lake Avenue Nutrition
4.6
★★★★★
(10389 ratings)
Provides 400mg SAMe at $0.77 per serving, offering a highly competitive price point for a top-rated product with exceptional consumer satisfaction.
Other sellers (2)
98 Performance

SAMe 400 mg

Lake Avenue Nutrition
4.6
★★★★★
(10389 ratings)
Highly comparable in quality and dosage, this alternative boasts an even higher number of positive reviews, indicating slightly superior widespread satisfaction.
Other sellers (2)
95 Performance

SAMe 400 mg

NOW
4.6
★★★★★
(1853 ratings)
This alternative from the highly-trusted NOW brand provides a similar high-quality 400mg SAMe experience with massive user backing, often chosen for its robust value.
Other sellers (4)
55 Performance

SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
5.0
★★★★★
(11 ratings)
This alternative includes crucial B vitamin cofactors alongside SAMe, a beneficial addition not found in the analyzed product, which can enhance overall efficacy for some users.
Other sellers (0)
96 Budget

SAMe 400 mg

Nutricost
4.6
★★★★★
(980 ratings)
This alternative offers the same 400mg SAMe dose at a significantly lower price per serving ($0.59 vs $0.82), providing superior cost-effectiveness.
Other sellers (1)
95 Budget

SAMe 400 mg

NOW
4.6
★★★★★
(1853 ratings)
This alternative offers a 400mg SAMe dose from a highly trusted brand at a better price per serving ($0.68 vs $0.82), making it a great value option.
Other sellers (4)
89 Budget

SAMe 400 mg

Swanson
4.6
★★★★★
(285 ratings)
Providing 400mg SAMe at a competitive $0.69 per serving, this Swanson product offers a good balance of dose and affordability.
Other sellers (1)
96 Value

SAMe 400 mg

Nutricost
4.6
★★★★★
(980 ratings)
Offers an outstanding value for 400mg SAMe at $0.59 per serving, providing superior cost-effectiveness while maintaining a high dose.
Other sellers (1)
95 Value

SAMe 400 mg

NOW
4.6
★★★★★
(1853 ratings)
This alternative delivers 400mg SAMe at $0.68 per serving, offering excellent value from a highly trusted brand, balancing high quality with affordability.
Other sellers (4)
98 Value

SAMe 400 mg

Lake Avenue Nutrition
4.6
★★★★★
(10389 ratings)
Provides 400mg SAMe at $0.77 per serving, offering a highly competitive price point for a top-rated product with exceptional consumer satisfaction.
Other sellers (2)
98 Performance

SAMe 400 mg

Lake Avenue Nutrition
4.6
★★★★★
(10389 ratings)
Highly comparable in quality and dosage, this alternative boasts an even higher number of positive reviews, indicating slightly superior widespread satisfaction.
Other sellers (2)
95 Performance

SAMe 400 mg

NOW
4.6
★★★★★
(1853 ratings)
This alternative from the highly-trusted NOW brand provides a similar high-quality 400mg SAMe experience with massive user backing, often chosen for its robust value.
Other sellers (4)
55 Performance

SAMe with Vitamins B-6 B-12 and 5-MTHF

Designs for Health
5.0
★★★★★
(11 ratings)
This alternative includes crucial B vitamin cofactors alongside SAMe, a beneficial addition not found in the analyzed product, which can enhance overall efficacy for some users.
Other sellers (0)
flagReport alternatives

SuppHelper

Compare supplements smarter. Science-backed, user-rated, updated daily.

Explore

  • Compare Supplements
  • Health Goals
  • Stacks

Legal

  • Privacy Policy
  • Terms of Use
  • Medical Disclaimer

Stay in the Loop

© 2025 SuppHelper. All rights reserved.