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GI-Revive

Designs for Health
4.8
★ ★ ★ ★ ★
(57 ratings)
N-Acetyl Glucosamine 1000 mg
Glutamine 1500 mg
Aloe 300 mg
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Score67
A broad combination of gut-lining nutrients and soothing botanicals is well aligned with digestive support. High cost plus unresolved aloe and glucosamine source details limit its practicality.
How scoring works
Quantity:210 Capsule(s) • (30 servings)
Goals:
Digestive Health
Joint Health
Skin Health

Score 67

A broad combination of gut-lining nutrients and soothing botanicals is well aligned with digestive support. High cost plus unresolved aloe and glucosamine source details limit its practicality.
How scoring works
$99.99($3.33 per serving)
iHerb
$ 99.99
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Analysis

L-glutamine at 1.5 g, N-acetyl glucosamine at 1 g, citrus pectin at 1 g, and zinc carnosine provide the most meaningful gut-lining ingredients. The amounts are clear, though glutamine remains modest compared with a dedicated gram-level powder.

DGL, aloe, slippery elm, marshmallow, mucin, chamomile, and okra broaden the soothing and barrier-support approach. The aloe label does not confirm inner-leaf purification or aloin removal, while the N-acetyl glucosamine source is not disclosed.

Seven capsules are required for one serving, which is cumbersome and provides less direct upper-digestive contact than powder. Joint and skin relevance comes mostly from N-acetyl glucosamine, with only small MSM and quercetin amounts. The very high serving cost and capsule burden weaken value.

Who is it for
  • Adults seeking a broad digestive-lining formula
  • People who want glutamine with zinc carnosine and demulcent herbs
  • Users able to verify the N-acetyl glucosamine source
Best for
  • Digestive-lining support
  • Multi-ingredient gut formulas
  • DGL, aloe, and demulcent-herb combinations

Pros

  • Provides 1.5 g glutamine
  • Includes 1 g N-acetyl glucosamine
  • Adds zinc carnosine and citrus pectin
  • Clearly lists individual ingredient amounts

Cons

  • Glutamine is modest for a dedicated supplement
  • Aloe purification and aloin removal are not stated
  • N-acetyl glucosamine source is not disclosed
  • The very high serving cost and capsule burden weaken value.

Warnings

  • The N-acetyl glucosamine source is not stated, so people with shellfish allergy cannot confirm suitability.
  • Aloe purification and aloin removal are not verified, leaving potential laxative compounds uncertain.
  • Cat’s claw and the broad botanical combination may interact with immune-modulating medicines; regular use with those medicines needs clinician review.

Nutrient quality

80 Highest impact

Zinc carnosine is a useful named form, while most botanical extracts lack standardized strength or sourcing details; core ingredients have substantial amounts, although glutamine remains moderate for focused use. The listed doses do not show an obvious excess for the intended use; the ingredients coherently target digestive barrier and soothing support; most additions have a reasonable digestive role despite the formula length.

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Ingredient transparency

75 High impact

Every listed active has a specific amount; no proprietary blend hides key doses. Names are mostly clear, but extract concentration, plant parts, and sources are often missing; serving directions and inactive ingredients are not included in the supplied details.

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Customer satisfaction

68 High impact

The supplied aggregate average is very favorable, though no individual feedback is available; the rating sample is moderate, but no individual feedback is supplied. Detailed feedback is absent, so repeated complaints cannot be assessed; real-world fit with the intended purpose remains uncertain.

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Value for money

40 Lower impact

Formula breadth is good, but the premium cost is difficult to justify fully; a high serving cost and large capsule burden weaken daily value. The added ingredients generally contribute to digestive support; similar digestive formulas may be more economical and easier to take.

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Report analysis

Goals

Digestive Health
Impact
High effect
A- Goal FitB- Strength of SupportB+ CoverageB Formula Quality
Glutamine · 1500 mgN-Acetyl Glucosamine · 1000 mg

Glutamine, zinc carnosine, pectin, DGL, aloe, and demulcent herbs create a directly targeted digestive formula. The combination addresses intestinal lining support, mucosal soothing, and modest stool regulation.

Several actives are meaningfully dosed, though glutamine remains below a stronger gram-level target and some extracts lack standardization. The seven-capsule serving and shellfish-source uncertainty for N-acetyl glucosamine are practical limitations.

Study evidence
Aloe Supportive 7 studies
Glutamine Supportive 37 studies
Joint Health
Impact
High effect
B Goal FitB+ Strength of SupportC+ CoverageD+ Formula Quality
N-Acetyl Glucosamine · 1000 mg

N-acetyl glucosamine at 1000 mg supplies a building block for glycosaminoglycans and hyaluronic acid, supporting cartilage and joint lubrication. The amount is substantial and individually disclosed.

Most companion ingredients are aimed at digestive lining support, while MSM is present only at a small amount for joints. The source of N-acetyl glucosamine is not stated, leaving uncertainty for people with shellfish allergy.

Study evidence
N-Acetyl Glucosamine Supportive 3 studies
Skin Health
Impact
High effect
C+ Goal FitB Strength of SupportC+ CoverageB- Formula Quality
N-Acetyl Glucosamine · 1000 mg

N-acetyl glucosamine supplies a meaningful precursor related to hyaluronic acid and skin hydration. Zinc carnosine, MSM, and quercetin add secondary support, though the blend was created for digestive health.

The N-acetyl glucosamine amount is substantial and fully listed. Its source and isomer are not stated, so people with shellfish allergy cannot confirm whether the ingredient is appropriate.

Study evidence
N-Acetyl Glucosamine Supportive 7 studies

Ingredients

IngredientAmount per serving
L-Glutamine
1500 mg
N-Acetyl Glucosamine
1000 mg
Citrus Pectin
1000 mg
Deglycyrrhizinated Licorice
400 mg
Aloe vera extract
300 mg
Slippery Elm
200 mg
Mucin
200 mg
Marshmallow
100 mg
Chamomile
100 mg
Okra extract
100 mg
Cat's Claw
100 mg
Methylsulfonylmethane
100 mg
Quercetin
100 mg
Prune powder
100 mg
Zinc Carnosine
75 mg
Gluten Free Adults 18–50
Report overview
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

The formula provides a high-potency, fully disclosed N-acetyl glucosamine dose in vegetarian capsules. It does not specify the D-isomer or disclose whether the ingredient comes from shellfish or fermentation, leaving an important allergen question unresolved. The high serving cost is partly offset by several substantial companion ingredients, though taking seven capsules per serving may be inconvenient.

Glutamine · 1500 mg OverallScore68
B- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyB Value

Standard L-glutamine is clearly identified, but no branded or pharmaceutical-grade purity claim is supplied. The 1,500 mg serving is meaningful yet remains below the stronger therapeutic range, and reaching 3 g would require fourteen capsules. Cost per gram is high, although substantial aloe vera, zinc carnosine, pectin, licorice, and other gut-supportive ingredients justify neutral complex-formula value.

Aloe · 300 mg OverallScore62
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

The aloe extract amount is substantial and clearly disclosed, but the label does not identify the plant part, purification, or active-polysaccharide standardization. Capsules provide convenient delivery but reduce direct contact with the upper digestive tract. The serving is expensive, though meaningful amounts of DGL and slippery elm add relevant digestive support.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of N-acetyl-glucosamine on stratum corneum desquamation and water content in human skin.
    Mammone T; Gan D; Fthenakis C; Marenus K · Journal of cosmetic science · 2009
    Clinical trialSkin Health forN-Acetyl Glucosamine
  2. Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine.
    Bissett DL; Robinson LR; Raleigh PS; Miyamoto K; Hakozaki T; Li J; Kelm GR · Journal of cosmetic dermatology · 2007
    Randomized trial50 participantsSkin Health forN-Acetyl Glucosamine
  3. Evaluation of the effect of N-acetyl-glucosamine administration on biomarkers for cartilage metabolism in healthy individuals without symptoms of arthritis: A randomized double-blind placebo-controlled clinical study.
    Tomonaga A; Watanabe K; Fukagawa M; Suzuki A; Kurokawa M; Nagaoka I · Experimental and therapeutic medicine · 2020
    Randomized trial65 participantsJoint Health forN-Acetyl Glucosamine
  4. Oral polymeric N-acetyl-D-glucosamine and osteoarthritis.
    Rubin BR; Talent JM; Kongtawelert P; Pertusi RM; Forman MD; Gracy RW · The Journal of the American Osteopathic Association · 2001
    Randomized trialJoint Health forN-Acetyl Glucosamine
  5. Improvement of intestinal permeability with alanyl-glutamine in HIV patients: a randomized, double blinded, placebo-controlled clinical trial.
    Leite RD; Lima NL; Leite CA; Farhat CK; Guerrant RL; Lima AA · Arquivos de gastroenterologia · 2013
    Randomized trial46 participantsDigestive Health forGlutamine
  6. Treatment of acute diarrhea with oral rehydration solutions containing glutamine.
    Ribeiro Júnior H; Ribeiro T; Mattos A; Palmeira C; Fernandez D; Sant'Ana I; Rodrigues I; Bendicho MT; Fontaine O · Journal of the American College of Nutrition · 1994
    Randomized trial120 participantsDigestive Health forGlutamine
  7. Prevention of acute radiation-induced Proctitis by Aloe vera: a prospective randomized, double-blind, placebo controlled clinical trial in Pelvic Cancer patients.
    Sahebnasagh A; Ghasemi A; Akbari J; Alipour A; Lashkardoost H; Ala S; Hosseinimehr SJ; Salehifar E · BMC complementary medicine and therapies · 2020
    Randomized trial42 participantsDigestive Health forAloe
  8. Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial.
    Sahebnasagh A; Ghasemi A; Akbari J; Alipour A; Lashkardoost H; Ala S; Salehifar E · Journal of alternative and complementary medicine (New York, N.Y.) · 2017
    Randomized trial20 participantsDigestive Health forAloe
  9. Aloe vera for Prevention of Acute Radiation Proctitis in Colorectal Cancer a Preliminary Randomized, Placebo-Controlled Clinical Trial.
    Sahebnasagh A; Saghafi F; Ghasemi A; Akbari J; Alipour A; Habtemariam S; Safdari M; Ghaleno HR; Salehifar E · Journal of gastrointestinal cancer · 2022
    Randomized trial20 participantsDigestive Health forAloe
  10. A Pilot Study of the Effect of Aloe barbadensis Mill. Extract (AVH200®) in Patients with Irritable Bowel Syndrome: a Randomized, Double-Blind, Placebo-Controlled Study.
    Størsrud S; Pontén I; Simrén M · Journal of gastrointestinal and liver diseases : JGLD · 2016
    Randomized trial68 participantsDigestive Health forAloe
  11. A Randomised, Cross-Over, Placebo-Controlled Study of Aloe vera in Patients with Irritable Bowel Syndrome: Effects on Patient Quality of Life.
    Hutchings HA; Wareham K; Baxter JN; Atherton P; Kingham JG; Duane P; Thomas L; Thomas M; Ch'ng CL; Williams JG · ISRN gastroenterology · 2011
    Randomized trial110 participantsDigestive Health forAloe
  12. Effect of perioperative glutamine-enriched nutritional support on patients with colorectal cancer: A systematic review and meta-analysis.
    Huang Y; Yang XZ; Qin SH; Zhang T; Xie M; Wang JW · World journal of gastrointestinal surgery · 2026
    Meta-analysis1,643 participants27 studies pooledDigestive Health forGlutamine
  13. Glutamine prevents diarrhea in colorectal cancer patients undergoing chemotherapy or chemoradiotherapy: a meta-analysis.
    Chen L; Wang D; Meng C; Sun H; Li R; Miao G; Liu P · BMC gastroenterology · 2025
    Meta-analysis311 participants5 studies pooledDigestive Health forGlutamine
  14. Glutamine supplementation reduces markers of intestinal permeability during running in the heat in a dose-dependent manner.
    Pugh JN; Sage S; Hutson M; Doran DA; Fleming SC; Highton J; Morton JP; Close GL · European journal of applied physiology · 2018
    Randomized trial10 participantsDigestive Health forGlutamine
  15. Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin A in children with acute diarrhea.
    Yalçin SS; Yurdakök K; Tezcan I; Oner L · Journal of pediatric gastroenterology and nutrition · 2004
    Randomized trial128 participantsDigestive Health forGlutamine
  16. Effects of N-acetyl glucosamine and chondroitin sulfate supplementation on knee pain and self-reported knee function in middle-aged and older Japanese adults: a randomized, double-blind, placebo-controlled trial
    Taishi Tsuji, Jieun Yoon, Naruki Kitano, Tomohiro Okura, Kiyoji Tanaka · Aging Clinical and Experimental Research · 2016
    Randomized trial50 participantsJoint Health forN-Acetyl Glucosamine
  17. A randomized, investigator-blinded, controlled pilot study to evaluate the safety and efficacy of a poly-N-acetyl glucosamine-derived membrane material in patients with venous leg ulcers.
    Kelechi TJ; Mueller M; Hankin CS; Bronstone A; Samies J; Bonham PA · Journal of the American Academy of Dermatology · 2012
    Randomized trial82 participantsSkin Health forN-Acetyl Glucosamine
  18. Poly-N-acetyl glucosamine nanofibers for negative-pressure wound therapies.
    Fulco I; Erba P; Valeri RC; Vournakis J; Schaefer DJ · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2016
    Randomized trial20 participantsSkin Health forN-Acetyl Glucosamine
  19. Preparation, characterization, and moisturizing effect of liposomes containing glucosamine and N-acetyl glucosamine.
    Malaekeh-Nikouei B; Golmohammadzadeh S; Salmani-Chamanabad S; Mosallaei N; Jamialahmadi K · Journal of cosmetic dermatology · 2014
    Clinical trialSkin Health forN-Acetyl Glucosamine