Ubiquinol 100 mg

Ubiquinol 100 mg

NOW4.8 (15,065 ratings)
Format:Softgel Quantity: 60 Softgel(s) · 60 servings
Goals
$27.97 $0.46 per serving

Product analysis

69 out of 100

Ubiquinol 100 mg offers focused CoQ10 support for normal cellular energy production and may help some measures of blood-vessel function. Benefits for tiredness are less certain in people who already feel well.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

CoQ10 is clearly identified, but a form-quality advantage has not been established. The name alone does not show better absorption than other CoQ10 preparations.

Ingredient Transparency100

The CoQ10 amount and form are both stated. That makes the single active straightforward to compare with alternatives.

Value For Money60

The CoQ10 serving offers moderate value at its stated cost. A better-absorbed or more effective preparation cannot be assumed from that price.

Customer Satisfaction93

Customers give consistently favorable ratings across a large review base. The volume makes the satisfaction picture more established, without proving health benefits.

Product Focus73

A single active keeps the formula focused on CoQ10-related support. Its strongest connection is to selected blood-vessel measures, while routine energy and broader benefits remain less certain.

Format
Softgel
Container
60 Softgel(s)
Per serving
$0.46
Customer rating
4.8 · 15,065 ratings
Report analysis

Goals

Cardiovascular Support
Impact
Highest effect
A Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Coenzyme Q10 may support selected blood-pressure, lipid or blood-vessel lining measures. The supplied findings come from people with abnormal lipids or endothelial dysfunction, so they do not establish the same benefit for every adult. The disclosed serving receives full preparation-specific amount recognition, without proving prevention of cardiovascular events or a uniquely superior delivery form.

How this product is rated for Cardiovascular Support

Ingredient fit93

Coenzyme Q-10 is the main recognized ingredient; its disclosed serving receives full amount recognition.
Goal fit
The recognized ingredients dominate the formula, with links to other goals reducing its cardiovascular specificity.
Dose adequacy
The disclosed serving receives full amount recognition, which does not establish greater benefit or a personal dose requirement.

Pathways60

The strongest assigned contribution concerns endothelial nitric-oxide function. Other cardiovascular mechanisms have less or no assigned coverage.
Depth
The strongest assigned support concerns endothelial nitric-oxide function, rather than comprehensive cardiovascular protection.
Breadth
Only endothelial nitric-oxide function reaches the coverage threshold.

Evidence88

Coenzyme Q-10 leads the evidence findings. The supplied population and preparation limits remain relevant to expectations.
Evidence strength
Coenzyme Q-10 provides the leading evidence contribution; its marker findings do not establish prevention of cardiovascular events.
Studied preparation
The counted preparations are recognized as studied, with the population and exposure distinctions described for the relevant ingredients.

Formulation logic100

The counted ingredients have no unmet partner requirement or identified configured conflict; amount thresholds are considered separately.
Partner coverage
No unmet partner requirement is identified for the counted ingredients; combining them does not establish an added benefit.
Conflicts
No configured ingredient conflict was identified.
Effective doses
All counted ingredients clear the minimum amount threshold, which is distinct from a proven effective dose.
Study evidence
Heart Health
Impact
Highest effect
A Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Ubiquinol may support the ability of blood vessels to widen. The 100 mg per serving matches an exposure studied in adults with abnormal blood lipids and impaired vessel function. That small trial found improved vessel widening, without establishing fewer cardiovascular events or superiority of a higher dose. The declared identity supports a cautious comparison, without proving this finished product is equivalent to the studied product.

How this product is rated for Heart Health

Ingredient fit93

Ubiquinol gives this formula a focused connection to blood-vessel function. The declared ubiquinol amount matches the saved exposure range; a serving does not establish daily use.
Goal fit
Ubiquinol gives this formula a focused connection to blood-vessel function.
Dose adequacy
The declared ubiquinol amount matches the saved exposure range; a serving does not establish daily use.

Pathways60

The findings concentrate on blood-vessel widening, with limited breadth across other heart-health aspects.
Depth
Ubiquinol accounts for the finding on blood-vessel widening.
Breadth
Only the blood-vessel widening aspect meets the saved coverage criterion.

Evidence98

Ubiquinol has relevant small-trial evidence in a selected population. The declared ubiquinol identity matches the supported preparation category, without proving finished-product equivalence.
Evidence strength
Ubiquinol has relevant small-trial evidence in a selected population.
Studied preparation
The declared ubiquinol identity matches the supported preparation category, without proving finished-product equivalence.

Formulation logic100

The counted ingredients have no missing required partner, and no specified conflict was identified. The counted amounts meet the saved minimum criterion.
Partner coverage
The counted ingredients have no missing required partner.
Conflicts
No specified ingredient conflict was identified in the supplied facts.
Effective doses
Ubiquinol meets the saved amount criterion.
Study evidence
Energy
Impact
High effect
B- Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Ubiquinol is a form of CoQ10 involved in mitochondrial energy production. The supplied evidence supports limited, preparation-specific fatigue benefit, with clinical findings not automatically applying to healthy adults. Its 100 mg per serving receives partial amount recognition in the saved result. The form does not establish an absorption or energy advantage over other CoQ10 preparations.

How this product is rated for Energy

Ingredient fit73

Ubiquinol is the single relevant ingredient.
Goal fit
Ubiquinol is the single relevant ingredient.
Dose adequacy
The 100 mg per serving receives partial amount recognition.

Pathways40

CoQ10 contributes to mitochondrial energy production, the only covered pathway.
Depth
Mitochondrial energy production receives partial coverage from CoQ10.
Breadth
Only one listed pathway receives meaningful coverage.

Evidence95

CoQ10 provides the strongest recognized evidence contribution at its saved amount. Its practical benefit remains subject to the population and nutrient-status limits described above.
Evidence strength
CoQ10 leads the evidence contribution among ingredients at recognized amounts.
Studied preparation
The credited ingredients meet the saved preparation criterion; this does not establish benefit for every user.

Formulation logic100

The credited ingredients require no missing partner, and no configured conflict was found. All credited amounts pass the saved minimum contribution threshold.
Partner coverage
Every credited ingredient can contribute without a missing required partner.
Conflicts
No configured ingredient conflict was identified.
Effective doses
All credited ingredients pass the saved minimum amount threshold; this is not proof of a clinically effective dose.
Study evidence
Longevity
Impact
Moderate effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Ubiquinol is a form of CoQ10 involved in cellular energy and antioxidant activity. Its 100 mg serving has not been matched to the particular CoQ10 preparation used for the supplied skin-appearance findings.

How this product is rated for Longevity

Ingredient fit73

1 assessed ingredient relate to healthy aging, alongside no other active ingredients. The product’s broader uses also affect its focus. The assessed amounts provide partial support relative to the saved comparison amounts; any undisclosed amount cannot add dose support.
Goal fit
1 assessed ingredient relate to healthy aging, alongside no other active ingredients. The product’s broader uses also affect its focus.
Dose adequacy
The assessed amounts provide partial support relative to the saved comparison amounts; any undisclosed amount cannot add dose support.

Pathways10

The strongest saved support concerns mitochondrial energy production, with limited coverage. No assessed function reaches the saved level for broad coverage.
Depth
The strongest saved support concerns mitochondrial energy production, with limited coverage.
Breadth
No assessed function reaches the saved level for broad coverage.

Evidence30

Coenzyme Q-10 supplies the strongest saved evidence contribution at an assessed amount. The support remains subject to that ingredient’s preparation and population limits. Preparation matching is incomplete: Coenzyme Q-10 is not matched to a studied preparation.
Evidence strength
Coenzyme Q-10 supplies the strongest saved evidence contribution at an assessed amount. The support remains subject to that ingredient’s preparation and population limits.
Studied preparation
Preparation matching is incomplete: Coenzyme Q-10 is not matched to a studied preparation.

Formulation logic100

The assessed ingredients can contribute independently or have their required partner present. No configured ingredient conflict was identified in the supplied assessment. 1 of 1 assessed ingredients reach the saved minimum for a meaningful amount.
Partner coverage
The assessed ingredients can contribute independently or have their required partner present.
Conflicts
No configured ingredient conflict was identified in the supplied assessment.
Effective doses
1 of 1 assessed ingredients reach the saved minimum for a meaningful amount.
Study evidence
Inflammation
Impact
Moderate effect
B- Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

The ubiquinol form here can't be assumed to provide the same anti-inflammatory effect as ubiquinone. Coenzyme Q10 has a role in cellular energy processes, but its relevance to inflammation is limited to changes in particular blood markers. Whether this ubiquinol serving reduces inflammation in a way you would notice remains unclear.

How this product is rated for Inflammation

Ingredient fit73

The serving declares 100 mg Coenzyme Q-10; these amounts alone do not establish a clinical anti-inflammatory effect.
Goal fit
Coenzyme Q10 provides the principal connection to this goal; its presence alone does not predict relief.
Dose adequacy
The serving declares 100 mg Coenzyme Q-10; these amounts alone do not establish a clinical anti-inflammatory effect.

Pathways19

The connection mainly concerns oxidative stress and related inflammatory markers, rather than demonstrated symptom relief.
Depth
The connection mainly concerns oxidative stress and related inflammatory markers, rather than demonstrated symptom relief.
Breadth
The ingredients do not demonstrate broad clinical effects across multiple inflammatory processes.

Evidence63

Coenzyme Q10 has limited inflammatory-marker relevance rather than a clear broad clinical benefit.
Evidence strength
Coenzyme Q10 has limited inflammatory-marker relevance rather than a clear broad clinical benefit.
Studied preparation
Ubiquinol cannot inherit a matching anti-inflammatory amount from ubiquinone.

Formulation logic100

No particular conflict or missing required partner is identified. Combining the ingredients does not itself establish an added anti-inflammatory effect.
Partner coverage
No missing required partner is identified.
Conflicts
No particular ingredient conflict is identified.
Effective doses
The declared amounts permit reference comparisons, which do not establish effective symptom relief.
Study evidence
Metabolism Support
Impact
High effect
B- Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Coenzyme Q10 participates in mitochondrial electron transport, helping cells carry out normal energy production. That role and changes in metabolic biomarkers do not establish that supplementation raises whole-body calorie expenditure. The declared amount is therefore a nutritional or mechanistic connection, without a demonstrated routine metabolism boost or preference for a particular form.

How this product is rated for Metabolism Support

Ingredient fit73

Coenzyme Q-10 provide the main connection. The included amounts provide only a partial match to reference exposures; this does not establish effective doses for raising calorie expenditure.
Goal fit
Coenzyme Q-10 provide the main metabolic connection, with little diversion to other ingredients.
Dose adequacy
The included amounts provide only a partial match to reference exposures; this does not establish effective doses for raising calorie expenditure.

Pathways17

The main connection concerns mitochondrial energy processes, which are not proof of increased whole-body calorie expenditure. No pathway reached the coverage threshold, so direct support for a metabolism boost remains limited.
Depth
The main connection concerns mitochondrial energy processes, which are not proof of increased whole-body calorie expenditure.
Breadth
No pathway reached the coverage threshold, so direct support for a metabolism boost remains limited.

Evidence75

CoQ10’s mitochondrial role and metabolic-marker findings do not establish a routine increase in whole-body energy expenditure.
Evidence strength
CoQ10’s mitochondrial role and metabolic-marker findings do not establish a routine increase in whole-body energy expenditure.
Studied preparation
The included preparations match the saved comparison, which does not establish a measured increase in energy expenditure.

Formulation logic100

No missing required partner or configured conflict was identified. The included amounts meet the minimum exposure comparison without demonstrating an extra benefit from combining them.
Partner coverage
No missing required partner was identified; the combination does not establish an additional metabolic-rate effect.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
The included ingredients meet the minimum exposure comparison, which does not establish an effective thermogenic or weight-loss dose.
Study evidence

Ingredients

IngredientAmount per servingScore
Ubiquinol (CoQ10)
100 mg 81
Gluten Free Adults 18–50 Dairy Free
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
Each serving provides 100 mg of CoQ10 as ubiquinol. The whole-product serving costs about $0.47.
How this ingredient is rated

Active Ingredient Quality & Bioavailability72

The saved facts identify the CoQ10 as ubiquinol. No specified delivery technology or absorption enhancer is recorded.
Molecular Form: Ubiquinol vs. Ubiquinone
CoQ10 is recorded as ubiquinol, its reduced form.
Formulation & Absorption Enhancers
No liposomal, micellar or nanoemulsion formulation or black pepper extract is recorded in the saved facts.

Dose, Safety & Label Transparency100

A serving provides 100 mg of CoQ10 as ubiquinol. The amount is disclosed, with no flagged additives or standard fillers recorded.
Clinical Dosage Alignment
A serving provides 100 mg of CoQ10 as ubiquinol.
Label Transparency & Fillers
The amount is disclosed, with no flagged additives or standard fillers recorded.

Value60

The whole-product price is about $0.47 per serving, placing it in the middle of the value comparison.
Price Per Effective Serving
The whole-product price is about $0.47 per serving, placing it in the middle of the value comparison.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  7. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  8. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  9. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  10. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  11. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  12. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  13. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Support forCoenzyme Q-10
  14. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  15. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsInflammation forCoenzyme Q-10
  16. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsInflammation forCoenzyme Q-10
  17. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledInflammation forCoenzyme Q-10
  18. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledInflammation forCoenzyme Q-10
  19. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsInflammation forCoenzyme Q-10
  20. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewLongevity forCoenzyme Q-10