Advanced Bone Support

Advanced Bone Support

Thorne4.7 (1,297 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 60 servings
Goals

Product analysis

70 out of 100

Advanced Bone Support combines calcium, magnesium and vitamin D to help meet nutrient needs for normal bone and mineral functions. Its B vitamins add related nutritional support, with usefulness depending on dietary needs.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality63

The identified calcium, B6 and boron forms provide some clear quality strengths. The quality of the other forms cannot be fully judged, so those strengths do not establish better results from the entire mix.

Ingredient Transparency95

All declared amounts and most forms are stated, making the serving contribution easy to compare. The exact folate form is unspecified.

Value For Money43

Calcium and B6 offer moderate value, while boron is less economical. Value for several other nutrients remains uncertain, so the complete purchase comparison is limited.

Customer Satisfaction83

Customer feedback is very positive across more than a thousand ratings. That provides a useful satisfaction signal without establishing changes in bone health.

Product Focus71

The clearest purpose is supplying nutrients for normal bone and mineral functions when intake is low. The limited exercise-related magnesium findings do not establish a routine testosterone increase.

Format
Capsule
Container
120 Capsule(s)
Per serving
$0.48
Customer rating
4.7 · 1,297 ratings
Report analysis

Goals

Everyday Health
Impact
Highest effect
B Ingredient FitB- PathwaysA- EvidenceA+ Formulation Logic
Folate · 166.6 mcg DFEVitamin B12 · 50 mcgVitamin D · 25 mcgMagnesium · 100 mgBoron · 3 mg

Calcium, magnesium and vitamin D contribute to normal bone and mineral functions when intake is low. B6, B12 and folate add blood-related nutritional roles, with their amounts making varying contributions against the saved references. Boron receives a saved contribution, but its limited mineral-metabolism research does not establish routine broad health benefit. The named mineral and vitamin forms do not establish superior effects.

How this product is rated for Everyday Health

Ingredient fit75

The selected serving provides a partial contribution against the saved amount references, with the recognized ingredients contributing to different degrees.
Goal fit
The relevant ingredients fit routine nutritional roles, although the product is linked to several health aims.
Dose adequacy
The selected serving provides a partial contribution against the saved amount references, with the recognized ingredients contributing to different degrees.

Pathways74

The strongest represented area is one-carbon metabolism and blood formation, reflecting the recognized ingredients and their amounts.
Depth
The strongest represented area is one-carbon metabolism and blood formation, reflecting the recognized ingredients and their amounts.
Breadth
The more substantially represented areas are one-carbon metabolism and blood formation, bone and mineral metabolism.

Evidence86

Magnesium provides the strongest recognized basis here; the supplied context still limits expectations for routine benefits in adequately nourished adults.
Evidence strength
Magnesium provides the strongest recognized basis here; the supplied context still limits expectations for routine benefits in adequately nourished adults.
Studied preparation
The recognized preparations meet the saved check; this does not establish superiority of the named forms or broad clinical benefits.

Formulation logic100

None of the defined ingredient-conflict conditions was triggered by the supplied facts.
Partner coverage
The recognized ingredients can contribute independently or have their required partners present; no added combined benefit is established.
Conflicts
None of the defined ingredient-conflict conditions was triggered by the supplied facts.
Effective doses
All recognized ingredients meet the saved minimum amount threshold; this is not a proven clinical treatment threshold.
Study evidence
Boron Supportive 6 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Impact
Moderate effect
C Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Magnesium · 100 mgVitamin D · 25 mcgBoron · 3 mg

Whether magnesium raises testosterone during everyday use is unclear. The hormone effects linked to magnesium depend on specific exercise conditions and don't translate reliably to routine use when nutrient intake is adequate. The declared amount alone can't show that it will increase the testosterone available in your blood.

How this product is rated for Testosterone Support

Ingredient fit64

Magnesium supplies the main nutrient connection to testosterone. Its practical value depends on the limits of that connection.
Goal fit
Magnesium provides a relevant nutrient connection, while the other ingredients don't imply an added testosterone benefit.
Dose adequacy
Boron 3 mg, Vitamin B6 20 mg, Vitamin D 25 mcg, plus other declared nutrients per serving; these amounts do not predict a testosterone increase.

Pathways20

Magnesium is linked to testosterone availability, although that effect is uncertain in everyday use.
Depth
Magnesium has a possible connection to testosterone availability, but a routine increase remains uncertain.
Breadth
The ingredients do not provide reliable grounds to expect several distinct testosterone effects.

Evidence79

The possible hormone effect of magnesium has limited relevance to routine use. The ingredient and amount cannot establish a predictable increase.
Evidence strength
Magnesium-related hormone effects have limited applicability to ordinary use, particularly when nutrient intake is adequate.
Studied preparation
Vitamin B6 adds uncertainty: its preparation does not provide a reliable basis for expecting higher testosterone.

Formulation logic100

No missing partner or particular ingredient conflict is identified. Combining the ingredients does not itself show an added hormone benefit.
Partner coverage
No missing ingredient partner is identified for the relevant ingredients.
Conflicts
No particular ingredient conflict is identified.
Effective doses
The relevant ingredient amounts are declared, but the amounts alone cannot show that testosterone will rise.
Study evidence
Boron Disputed 3 studies
Magnesium Disputed 5 studies
Vitamin D Supportive 56 studies

Ingredients

IngredientAmount per servingScore
Vitamin D (Vitamin D3)
25 mcg
Vitamin B6 (Pyridoxal 5-Phosphate)
20 mg 79
Folate
166.6 mcg DFE
Vitamin B12 (Methylcobalamin)
50 mcg
Calcium (DimaCal)
300 mg 83
Magnesium (Albion DiMagnesium Malate)
100 mg
Boron (Albion Bororganic)
3 mg 86
Gluten Free Adults 18–50
Report overview
A+ Ingredient Form & Label QualityC Dose, Safety & Label TransparencyC+ Value
The 20 mg of vitamin B6 per serving exceeds the European adult daily upper limit. It comes from Pyridoxal 5-Phosphate, and a whole-product serving costs about $0.48.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 source is Pyridoxal 5-Phosphate. The saved additive check flagged no artificial dyes, titanium dioxide or talc.
Vitamin B6 Form Identification
The B6 source is identified as Pyridoxal 5-Phosphate.
Clean Label and Excipient Purity
The saved additive check flagged no artificial dyes, titanium dioxide or talc.

Dose, Safety & Label Transparency65

Each serving supplies 20 mg of B6, exceeding the European adult daily upper limit. Total daily intake is unknown.
Vitamin B6 Dose & Safety Policy
The 20 mg per serving exceeds the European adult daily upper limit; total daily intake is unknown.
Label Transparency
The B6 chemical source is identified as Pyridoxal 5-Phosphate.

Value66

The whole-product serving price works out to about $0.024 per mg of B6, a moderate cost in this ingredient comparison.
Vitamin B6 Price Efficiency
The whole-product serving price works out to about $0.024 per mg of B6, a moderate cost in this ingredient comparison.
A+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD+ Value
A serving supplies 300 mg of calcium as dicalcium malate. The whole-product serving costs about $0.48.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The calcium source is dicalcium malate. The saved facts specify 300 mg of calcium per serving.
Calcium Form & Absorption Potential
The calcium source is dicalcium malate.
Elemental Calcium Transparency
The saved facts specify 300 mg of calcium per serving.

Dose, Safety & Label Transparency82

A serving supplies 300 mg of calcium. No configured artificial additives or flow agents were flagged; sugar information is unavailable.
Absorption-Optimized Serving Dose
A serving supplies 300 mg of calcium.
Formulation Purity & Additives
No configured artificial additives or flow agents were flagged; sugar information is unavailable.

Value50

The whole-product serving costs about $0.48.
Price Per Serving Efficiency
The whole-product serving costs about $0.48.
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Each serving provides 3 mg of boron as Bororganic Glycine. At the whole-product serving price, 3 mg of boron works out to about $0.48.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The identified boron form is Bororganic Glycine.
Boron Form & Bioavailability
The identified boron form is Bororganic Glycine.
Trademarked & High-Purity Sources
The evaluation records a branded source; that marker does not independently verify purity.

Dose, Safety & Label Transparency100

The label gives 3 mg of boron per serving, an amount aligned with the evaluation's general support criteria.
Elemental Dose Transparency
The label gives 3 mg of elemental boron per serving.
Dosage Efficacy & Safety Margin
The labeled 3 mg per serving aligns with the evaluation's general support criteria.

Value30

At the whole-product serving price, 3 mg of boron works out to about $0.48.
Price per 3mg Elemental Boron
At the whole-product serving price, 3 mg of boron works out to about $0.48.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsEveryday Health forBoron
  2. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialEveryday Health forBoron
  3. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsEveryday Health forBoron
  4. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsEveryday Health forBoron
  5. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsEveryday Health forBoron
  6. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  7. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  8. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  9. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  10. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  11. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledEveryday Health forMagnesium
  12. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsEveryday Health forMagnesium
  13. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsEveryday Health forMagnesium
  14. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsEveryday Health forMagnesium
  15. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsEveryday Health forMagnesium
  16. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsEveryday Health forVitamin B12
  17. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsEveryday Health forVitamin B12
  18. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsEveryday Health forVitamin B12
  19. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsEveryday Health forVitamin B12
  20. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsEveryday Health forVitamin B12