The Original Italian Blood Orange

The Original Italian Blood Orange

XTEND4.6 (11,086 ratings)
Format:Powder Quantity: 435 Gram(s) · 30 servings
Goals
$27.99 $0.93 per serving

Product analysis

43 out of 100

The Original Italian Blood Orange combines amino acids, minerals and vitamin B6 in a flavored serving. Undisclosed blend contents make the full mixture harder to compare.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality21

Most ingredient forms are unspecified, limiting quality comparisons. The potassium and amino-acid descriptions do not resolve the undisclosed blend contents.

Ingredient Transparency44

Most amounts are stated, but the carbohydrate amount is missing. Most forms and the blend breakdown are unspecified.

Value For Money48

Value varies across the ingredients, with favorable serving-cost and leucine comparisons. Glutamine and valine offer less value, while some other comparisons remain uncertain.

Customer Satisfaction89

Customer feedback is very positive across a large number of ratings. That gives a broad satisfaction picture without establishing immune benefits.

Product Focus35

The clearest health connection is to a narrow post-exercise glutamine context. That does not establish routine immune support, and the undisclosed blend prevents a complete ingredient count.

Format
Powder
Container
435 Gram(s)
Per serving
$0.93
Customer rating
4.6 · 11,086 ratings
Report analysis

Goals

Impact
Lower effect
D+ Ingredient FitF PathwaysF EvidenceB+ Formulation Logic
Potassium · 180 mg
Study evidence
Potassium Supportive 2 studies
Valine Not classified

No linked studies yet.

Impact
Situational effect
F Ingredient FitF PathwaysF EvidenceB Formulation Logic
Vitamin B6 · 640 mcg
Study evidence
Potassium Supportive 182 studies
Vitamin B6 Supportive 44 studies
Immunity
Impact
Moderate effect
D+ Ingredient FitF PathwaysB+ EvidenceA- Formulation Logic

Glutamine at 2.5 g relates to post-exercise research, but the specific endurance-exercise setting and timed drinks limit transfer to routine immune support. Vitamin B6 supports normal immune-cell function, though its individual amount remains unresolved here.

How this product is rated for Immunity

Ingredient fit51

2 assessed ingredients relate to immunity alongside 5 other active ingredients, giving the formula a broader focus. The assessed amounts offer limited support against the saved benchmarks; unresolved amounts cannot add support.
Goal fit
2 assessed ingredients relate to immunity alongside 5 other active ingredients, giving the formula a broader focus.
Dose adequacy
The assessed amounts offer limited support against the saved benchmarks; unresolved amounts cannot add support.

Pathways19

The strongest saved connection is to barrier and antimicrobial defense, with limited coverage. None of the three target areas reaches the saved threshold for substantial coverage.
Depth
The strongest saved connection is to barrier and antimicrobial defense, with limited coverage.
Breadth
None of the three target areas reaches the saved threshold for substantial coverage.

Evidence83

Glutamine provides the strongest saved evidence among ingredients meeting the amount benchmark. That finding does not establish fewer infections from the whole formula. The assessed ingredients meeting the amount benchmark are recorded as matching studied preparations.
Evidence strength
Glutamine provides the strongest saved evidence among ingredients meeting the amount benchmark. That finding does not establish fewer infections from the whole formula.
Studied preparation
The assessed ingredients meeting the amount benchmark are recorded as matching studied preparations.

Formulation logic88

The assessed ingredients can act independently or have their required partner present. No configured ingredient conflicts were identified in the saved findings. 1 of 2 assessed ingredients meet the saved minimum amount benchmark. Vitamin B6 fall below it or have unresolved amounts.
Partner coverage
The assessed ingredients can act independently or have their required partner present.
Conflicts
No configured ingredient conflicts were identified in the saved findings.
Effective doses
1 of 2 assessed ingredients meet the saved minimum amount benchmark. Vitamin B6 fall below it or have unresolved amounts.
Study evidence
Glutamine Supportive 36 studies

Ingredients

IngredientAmount per servingScore
Calories
0 Calorie(s)
Total Carbohydrates
0 Gram(s)
Vitamin B6 (Pyridoxine Hydrochloride)
640 mcg
Sodium
220 mg 63
Potassium
180 mg 49
L-Leucine
3500 mg 84
L-Glutamine
2500 mg 64
L-Isoleucine
1750 mg 81
L-Valine
1750 mg 82
Electrolyte Blend
1140 mg
Citrulline Malate
1000 mg
Adults 18–50 Sugar Free Women
Report overview
Leucine · 3500 mg OverallScore84
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
Each serving provides 3,500 mg of L-leucine. The amount is associated with stimulating muscle protein synthesis in the evaluation.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

L-leucine is identified; further source details are not established in the saved facts.
Isomer Purity and Sourcing
L-leucine is identified; further source details are not established in the saved facts.

Dose, Safety & Label Transparency100

The leucine amount is individually recorded at 3,500 mg per serving. The amount is associated with stimulating muscle protein synthesis in the evaluation.
Muscle Protein Synthesis (MPS) Dosage
The 3,500 mg per serving is an amount the evaluation associates with stimulating muscle protein synthesis.
Dosage Transparency
The saved facts provide a specific leucine amount of 3,500 mg per serving.

Value80

The recorded whole-product serving price corresponds to about $0.27 per gram of leucine.
Price per Gram of Active Leucine
The recorded whole-product serving price corresponds to about $0.27 per gram of leucine.
Valine · 1750 mg OverallScore82
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
Each serving provides 1,750 mg of L-valine. The whole-product cost works out to about $0.53 per gram of valine.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The ingredient is identified as L-valine. The saved facts indicate a general quality claim but no sport-specific certification.
Valine Isomer and Source Type
The ingredient is identified as L-valine.
Third-Party Sport Certifications
The saved facts indicate a general testing or manufacturing quality claim, but do not identify a sport-specific certification.

Dose, Safety & Label Transparency100

The serving individually discloses 1,750 mg of valine, a relatively substantial amount.
Valine Dosage Efficacy
The serving provides 1,750 mg of valine, a relatively substantial amount.
Label Transparency and Proprietary Blends
The valine amount is individually disclosed as 1,750 mg per serving.

Value40

Based on whole-product servings, the cost works out to about $0.53 per gram of valine.
Price Per Gram of Valine
Based on whole-product servings, the cost works out to about $0.53 per gram of valine.
Isoleucine · 1750 mg OverallScore81
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD+ Value
A serving provides 1,750 mg of free-form L-isoleucine, a larger amount in this comparison. A general third-party testing claim is recorded, and a whole-product serving costs about $0.93.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The isoleucine is in free form; a fermented or plant-based source is not recorded.
Free-Form vs. Protein-Bound
L-isoleucine is an isolated, free-form amino acid, which does not need protein digestion before absorption.
Sourcing and Purity Signals
No fermented or plant-based sourcing claim is recorded in the saved facts.

Dose, Safety & Label Transparency92

The serving contains 1,750 mg of isoleucine. A general third-party testing claim is recorded.
Isoleucine Potency per Serving
A serving provides 1,750 mg of isoleucine, a larger amount in this comparison.
Label Transparency & Blend Disclosure
The individual isoleucine amount is disclosed as 1,750 mg per serving.
Third-Party Safety & Sport Testing
A general third-party testing claim is recorded; sport-specific certification is not recorded.

Value50

A whole-product serving costs about $0.93.
Price per Serving Efficiency
A whole-product serving costs about $0.93.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis.
    Vårvik FT; Bjørnsen T; Gonzalez AM · International journal of sport nutrition and exercise metabolism · 2021
    Meta-analysis137 participants8 studies pooledEnergy forCitrulline
  2. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study.
    Suzuki T; Morita M; Kobayashi Y; Kamimura A · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial22 participantsEnergy forCitrulline
  3. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
    Pérez-Guisado J; Jakeman PM · Journal of strength and conditioning research · 2010
    Randomized trial41 participantsEnergy forCitrulline
  4. Citrulline/malate promotes aerobic energy production in human exercising muscle.
    Bendahan D; Mattei JP; Ghattas B; Confort-Gouny S; Le Guern ME; Cozzone PJ · British journal of sports medicine · 2002
    Single-arm trial18 participantsEnergy forCitrulline
  5. The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants.
    Farney TM; Bliss MV; Hearon CM; Salazar DA · Journal of strength and conditioning research · 2019
    Randomized trial12 participantsEnergy forCitrulline
  6. [Efficacy of potassium N-acetylaminosuccinate (Cogitum) in the treatment of asthenic syndrome: results of double-blind placebo-controlled trial].
    Esin RG; Khayrullin IK; Esin OR; Fatykhova AF; Gismatullina EI; Isaeva YN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2023
    Randomized trial37 participantsEnergy forPotassium
  7. Human resting energy expenditure in relation to dietary potassium.
    Dériaz O; Thériault G; Lavallée N; Fournier G; Nadeau A; Bouchard C · The American journal of clinical nutrition · 1991
    Randomized trial8 participantsEnergy forPotassium
  8. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledHeart Health forPotassium
  9. Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials.
    Poorolajal J; Zeraati F; Soltanian AR; Sheikh V; Hooshmand E; Maleki A · PloS one · 2017
    Meta-analysis1,213 participants23 studies pooledHeart Health forPotassium
  10. Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study.
    O'Donnell M; Mente A; Rangarajan S; McQueen MJ; O'Leary N; Yin L; Liu X; Swaminathan S; Khatib R; Rosengren A; Ferguson J; Smyth A; Lopez-Jaramillo P; Diaz R; Avezum A; Lanas F; Ismail N; Yusoff K; Dans A; Iqbal R; Szuba A; Mohammadifard N; Oguz A; Yusufali AH; Alhabib KF; Kruger IM; Yusuf R; Chifamba J; Yeates K; Dagenais G; Wielgosz A; Lear SA; Teo K; Yusuf S; PURE Investigators · BMJ (Clinical research ed.) · 2019
    Cohort study103,570 participantsHeart Health forPotassium
  11. Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies.
    D'Elia L; Cappuccio FP; Masulli M; La Fata E; Rendina D; Galletti F · Nutrients · 2023
    Meta-analysis332 participants5 studies pooledHeart Health forPotassium
  12. Effects of potassium supplementation on office, home, and 24-h blood pressure in patients with essential hypertension.
    Kawano Y; Minami J; Takishita S; Omae T · American journal of hypertension · 1999
    Randomized trial55 participantsHeart Health forPotassium
  13. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forVitamin B6
  14. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsHeart Health forVitamin B6
  15. Intake of folate, vitamin B6 and vitamin B12 and the risk of CHD: the Japan Public Health Center-Based Prospective Study Cohort I.
    Ishihara J; Iso H; Inoue M; Iwasaki M; Okada K; Kita Y; Kokubo Y; Okayama A; Tsugane S; JPHC Study Group · Journal of the American College of Nutrition · 2008
    Cohort study40,803 participantsHeart Health forVitamin B6
  16. The effect of B-vitamins on the prevention and treatment of cardiovascular diseases: a systematic review and meta-analysis.
    Miao Y; Guo Y; Chen Y; Lin Y; Lu Y; Guo Q · Nutrition reviews · 2024
    Meta-analysisHeart Health forVitamin B6
  17. Folate and vitamin B(6) intake and risk of acute myocardial infarction in Italy.
    Tavani A; Pelucchi C; Parpinel M; Negri E; La Vecchia C · European journal of clinical nutrition · 2005
    Case-control study985 participantsHeart Health forVitamin B6
  18. Meta-analysis of Glutamine on Immune Function and Post-Operative Complications of Patients With Colorectal Cancer.
    Yang T; Yan X; Cao Y; Bao T; Li G; Gu S; Xiong K; Xiao T · Frontiers in nutrition · 2021
    Meta-analysis2,201 participants31 studies pooledImmunity forGlutamine
  19. Efficacy of Glutamine in Treating Severe Acute Pancreatitis: A Systematic Review and Meta-Analysis.
    Dong S; Zhao Z; Li X; Chen Z; Jiang W; Zhou W · Frontiers in nutrition · 2023
    Meta-analysis1,201 participants30 studies pooledImmunity forGlutamine
  20. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial.
    Garrel D; Patenaude J; Nedelec B; Samson L; Dorais J; Champoux J; D'Elia M; Bernier J · Critical care medicine · 2003
    Randomized trial45 participantsImmunity forGlutamine