ACES+Zn

ACES+Zn

Carlson4.9 (2,123 ratings)
Format:Softgel Quantity: 360 Softgel(s) · 180 servings
Goals
$79.48 $0.44 per serving

About this product

The clearest use is filling selected nutrient gaps that affect normal immune function and skin maintenance. Vitamin C supports collagen formation, while zinc and selenium contribute to normal immune functions. Benefits are most relevant when intake is low, rather than when nutrient needs are already met.

The 15 mg zinc serving suits maintenance use, and zinc citrate is a favorable form for absorption. Selenium is supplied as L-selenomethionine, while the 500 mg vitamin C comes from buffered calcium ascorbate. The calcium declarations do not clearly show the proportions from each source, so they should not be added together without clarification.

The broader hair, nail, eye, hormone and metabolism uses need more qualification than the core nutritional roles. The 268 mg vitamin E amount does not establish added cosmetic or general health benefit with adequate intake. Value is uneven: zinc contributes reasonably to the serving cost, but vitamin C and selenium offer less compelling value.

Who is it for
  • Adults with identified dietary gaps in the included vitamins or minerals
  • People seeking maintenance-level zinc alongside vitamin C and selenium
Best for
  • Supporting normal immune functions when nutrient intake is low
  • Supporting normal collagen formation when vitamin C intake is inadequate

Pros

  • Zinc citrate supports good zinc absorption
  • The zinc amount fits a maintenance role
  • Buffered calcium ascorbate provides a clearly identified vitamin C source
  • L-selenomethionine is a favorable selenium form

Cons

  • Broader hormone and metabolism uses have limited support for adequately nourished adults
  • Vitamin C and selenium offer limited value for the serving cost
  • The split between calcium sources is not fully clear

Warnings

  • Count the 100 mcg selenium serving when combining supplements; excessive selenium intake can harm hair and nails.

Product analysis

61 out of 100

ACES+Zn supports normal immune function and skin repair when nutrient intake is low. It is relatively costly for its vitamin C and selenium amounts.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality54

Zinc and selenium use favorable forms, while quality remains uncertain for several other nutrients. Missing proportions in the calcium mix make that part harder to compare precisely.

Ingredient Transparency68

Declared amounts and the main vitamin and mineral forms are stated. Some precise forms and the proportions in the calcium mix are missing.

Value For Money35

The vitamin C and selenium contributions are relatively costly, while zinc offers moderate value. Value for several other nutrients remains uncertain.

Customer Satisfaction89

Customer feedback is very positive across many ratings. Those opinions do not establish cosmetic, immune or hormone benefits.

Product Focus69

The nutrients mainly support normal immunity and repair when intake is low. The broad range of health interests does not establish extra cosmetic, hormone or anti-aging benefits when nutrient needs are met.

Format
Softgel
Container
360 Softgel(s)
Per serving
$0.44
Customer rating
4.9 · 2,123 ratings
Report analysis

Goals

Immunity
Impact
Highest effect
B Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 500 mgZinc · 15 mgVitamin A · 3000 mcg RAESelenium · 100 mcg

Vitamin A supports protective barriers, zinc contributes to normal immune-cell function, and selenium supports normal immunity. Vitamin C offers limited cold-duration support with regular supplementation. Vitamin E received a saved contribution, but its mixed respiratory findings in older populations do not establish added protection for general adults.

How this product is rated for Immunity

Ingredient fit78

The relevant ingredients provide nutritional or narrowly qualified support for immunity; the serving amounts determine how much they contribute.
Goal fit
The formula includes relevant ingredients alongside ingredients intended for other purposes, so its focus on immunity is mixed.
Dose adequacy
The serving provides a partial overall match to the saved amount comparisons, with some ingredients contributing more than others.

Pathways100

The strongest supplied connection is to barrier and antimicrobial defense; this does not establish a clinical infection outcome.
Depth
The strongest supplied connection is to barrier and antimicrobial defense; this does not establish a clinical infection outcome.
Breadth
The supplied findings cover four immune areas, without establishing broader clinical protection.

Evidence100

The supplied evidence supports the relevant nutrient functions or limited population-specific findings; it does not establish general infection prevention.
Evidence strength
Vitamin C leads the saved evidence finding; its supported role remains limited to the supplied nutritional or regular-use context.
Studied preparation
The contributing preparations meet the saved preparation check; this does not establish that a particular form gives extra immune benefit.

Formulation logic100

The contributing ingredients do not require an additional partner, and no listed formulation conflict was triggered.
Partner coverage
The contributing ingredients can act independently; no missing required partner limits this finding.
Conflicts
No listed ingredient conflict was triggered by the supplied facts.
Effective doses
All contributing ingredients meet the saved minimum amount comparison, without proving a clinically effective regimen.
Study evidence
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Impact
High effect
B- Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Vitamin E · 268 mgVitamin C · 500 mg

Vitamin C has antioxidant functions; a large trial was null overall, with CRP improvement confined to people starting with elevated CRP. Zinc can help address inflammation associated with low zinc status, without established extra benefit when intake is adequate. Selenium supports antioxidant enzymes, but this does not establish added anti-inflammatory benefit above adequate intake.

How this product is rated for Inflammation

Ingredient fit73

Relevant ingredients form part of a broader formula with other actives. Retained quantities partly cover the comparison anchors; lower amounts do not establish proportionally smaller clinical effects.
Goal fit
Relevant ingredients form part of a broader formula with other actives.
Dose adequacy
Retained quantities partly cover the comparison anchors; lower amounts do not establish proportionally smaller clinical effects.

Pathways60

Oxidative and mitochondrial stress is the strongest recorded area; biological coverage does not itself establish symptom improvement.
Depth
Oxidative and mitochondrial stress is the strongest recorded area; biological coverage does not itself establish symptom improvement.
Breadth
Only oxidative and mitochondrial stress reached the coverage threshold.

Evidence96

Vitamin E leads the eligible evidence findings, while the clinical context limits expectations of general anti-inflammatory benefit.
Evidence strength
Vitamin E leads the eligible evidence findings, while the clinical context limits expectations of general anti-inflammatory benefit.
Studied preparation
Eligible preparations match the supplied comparison findings; this does not establish clinical benefit beyond the reviewed populations and outcomes.

Formulation logic100

No configured ingredient conflict was found. All retained ingredients meet the minimum comparison threshold; this threshold is not a proven effective dose for clinical anti-inflammatory relief.
Partner coverage
The retained ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was found.
Effective doses
All retained ingredients meet the minimum comparison threshold; this threshold is not a proven effective dose for clinical anti-inflammatory relief.
Study evidence
Selenium Supportive 34 studies
Vitamin C Supportive 50 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Skin Health
Impact
Highest effect
B+ Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 15 mgVitamin C · 500 mgSelenium · 100 mcgVitamin E · 268 mg

Vitamin C supports normal collagen formation and can restore impaired wound healing caused by low intake. Its presence does not establish added cosmetic benefit when intake is adequate. Vitamin E and selenium have antioxidant roles, but those roles do not establish routine oral skin improvement. The C/E combination does not match the supplied high-dose UV studies or establish sunscreen-like protection. Zinc also supports repair when intake is low.

How this product is rated for Skin Health

Ingredient fit83

The relevant ingredients provide a mixed skin-health connection. Declared amounts partly meet the saved exposure references.
Goal fit
Broader product aims or ingredients outside the credited skin-health roles reduce specific focus.
Dose adequacy
Amounts provide partial coverage of the saved exposure references; unknown quantities do not establish a usable skin-study exposure.

Pathways80

The strongest saved connection concerns uv antioxidant defence. Two assessed pathways reach the breadth threshold.
Depth
The strongest saved connection concerns uv antioxidant defence, without proving an improvement in that skin outcome.
Breadth
Two assessed pathways reach the saved breadth threshold.

Evidence100

Vitamin C leads the saved evidence contribution. The preparation check is satisfied for included ingredients, without establishing routine cosmetic improvement.
Evidence strength
Vitamin C supplies the leading contribution, subject to its specific outcome and population limits.
Studied preparation
Included ingredients satisfy the saved preparation check; this does not prove efficacy of the finished product.

Formulation logic100

No required partner is missing and no configured conflict was matched. Included ingredients clear the minimum amount comparison.
Partner coverage
No required partner is missing from the included contributions.
Conflicts
No configured ingredient conflict was matched.
Effective doses
Included ingredients clear the minimum amount comparison; this is distinct from a proven skin-treatment dose.
Study evidence
Selenium Supportive 22 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Everyday Health
Impact
High effect
B Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Selenium · 100 mcgZinc · 15 mgVitamin C · 500 mg

Vitamin C, Zinc and Selenium provide nutrients involved in normal antioxidant or immune functions. These nutritional contributions matter most when intake falls short; extra benefit with adequate intake is not established.

How this product is rated for Everyday Health

Ingredient fit79

The main relevant ingredients are Vitamin C, Zinc and Selenium. Their value is nutritional, rather than a demonstrated broad health improvement.
Goal fit
Vitamin C, Zinc and Selenium form the main nutritional contribution.
Dose adequacy
The selected serving provides a meaningful amount of Vitamin C, Zinc and Selenium.

Pathways60

The main areas represented are antioxidant and immune defence.
Depth
The strongest supported area is antioxidant and immune defence, through the relevant nutrients.
Breadth
The main areas represented are antioxidant and immune defence.

Evidence82

Selenium supports a nutritional role, chiefly when intake is low; this does not establish extra benefit with adequate intake.
Evidence strength
Selenium supports a nutritional role, chiefly when intake is low; this does not establish extra benefit with adequate intake.
Studied preparation
The relevant nutrient preparations were accepted in the saved comparison; no superior form or delivery benefit is established.

Formulation logic100

The relevant ingredients can contribute independently or have their required partner; their combination does not establish added benefit. No conflict was identified by the evaluated checks.
Partner coverage
The relevant ingredients can contribute independently or have their required partner; their combination does not establish added benefit.
Conflicts
No conflict was identified by the evaluated checks.
Effective doses
The counted ingredients reach the comparison’s minimum amount criterion; this is not proof of a clinical benefit.
Study evidence
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies
Impact
High effect
B+ Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Zinc · 15 mgVitamin E · 268 mgVitamin C · 500 mgVitamin A · 3000 mcg RAE

Vitamin A supports the visual cycle and dark adaptation when intake is inadequate. Vitamin C and vitamin E contribute to antioxidant defenses, while their eye-health findings and those for zinc concern defined combinations in selected people with age-related macular degeneration, rather than routine vision improvement.

How this product is rated for Eye Health

Ingredient fit80

The formula supplies nutrients relevant to eye nutrition, with amounts that vary in how fully they match the comparison references.
Goal fit
The formula includes ingredients considered for vision alongside a broader nutritional focus.
Dose adequacy
Declared amounts provide uneven coverage of the reference ranges; these ranges do not establish a proven routine vision dose.

Pathways60

The recorded findings concentrate on retinal and lens antioxidant defense. Other visual functions receive little or no coverage.
Depth
The strongest recorded coverage concerns retinal and lens antioxidant defense, without establishing a corresponding improvement in vision.
Breadth
Only one of the listed eye-function areas reaches the comparison’s coverage target; the findings do not support broad visual-performance claims.

Evidence84

The recorded evidence recognizes several nutrients, but their clinical and deficiency settings limit claims for routine vision improvement.
Evidence strength
Zinc drives the strongest recorded evidence finding, but the supplied context limits transfer to routine vision improvement.
Studied preparation
The counted ingredients match the preparations recognized in the saved comparison; this does not transfer study benefits to every user.

Formulation logic100

No missing partners or configured conflicts were identified. Amounts qualify unevenly where the supplied findings identify low or unresolved contributions.
Partner coverage
No missing ingredient partner was identified for the counted contributions; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients meet the comparison’s amount threshold, which is not a clinically proven effective dose.
Study evidence
Selenium Supportive 15 studies
Vitamin A Supportive 65 studies
Vitamin C Disputed 24 studies
Vitamin E Disputed 35 studies
Zinc Supportive 39 studies
Hair Health
Impact
Highest effect
B Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 15 mgVitamin C · 500 mg

Zinc can help address dietary shortfalls associated with diffuse shedding; extra intake does not establish regrowth when nutrient needs are met. Selenium and vitamin A have normal nutrient roles, but excessive intake can worsen hair loss rather than improve it.

How this product is rated for Hair Health

Ingredient fit76

Relevant ingredients sit within a broader formula aimed at other purposes, limiting its specific focus on hair. The serving amounts substantially match the saved comparisons, with some smaller contributions.
Goal fit
Relevant ingredients sit within a broader formula aimed at other purposes, limiting its specific focus on hair.
Dose adequacy
The serving amounts substantially match the saved comparisons, with some smaller contributions.

Pathways60

The strongest represented aspect is follicle antioxidant protection, with substantial representation; this is not proof of regrowth. The findings concentrate on one hair-related aspect rather than broad coverage.
Depth
The strongest represented aspect is follicle antioxidant protection, with substantial representation; this is not proof of regrowth.
Breadth
The findings concentrate on one hair-related aspect rather than broad coverage.

Evidence98

Zinc provides the strongest recognized evidence here, with its population and preparation limits. The qualifying preparations are recognized in the saved comparison; this does not establish universal hair benefit.
Evidence strength
Zinc provides the strongest recognized evidence here, with its population and preparation limits.
Studied preparation
The qualifying preparations are recognized in the saved comparison; this does not establish universal hair benefit.

Formulation logic100

The recognized ingredients have their required partners or can stand alone, with no matched ingredient conflict. The recognized ingredients meet the saved minimum amount comparison, which is not a proven clinical effect threshold.
Partner coverage
No required partner is missing for the recognized ingredients; this does not demonstrate synergy.
Conflicts
No listed ingredient conflict was matched; this does not establish individual suitability or medication compatibility.
Effective doses
The recognized ingredients meet the saved minimum amount comparison, which is not a proven clinical effect threshold.
Study evidence
Selenium Disputed 7 studies
Vitamin A Disputed 13 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per servingScore
Calories
15 Calorie(s)
Total Fat
1 Gram(s)
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Vitamin A (Beta-Carotene)
3000 mcg RAE
Vitamin C (Calcium Ascorbate)
500 mg 73
Vitamin E (D-Alpha-Tocopherol)
268 mg
Calcium (Dicalcium Phosphate, Calcium Ascorbate)
56 mg
Zinc (Zinc Citrate)
15 mg 68
Selenium (L-Selenomethionine)
100 mcg 77
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
+2
Each serving provides 100 mcg of selenium as L-selenomethionine, an organic form the evaluation regards as readily absorbed. The whole-product price works out to about $0.88 per 200 mcg of selenium, a relatively high cost in this comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

L-selenomethionine is an organic selenium form the evaluation regards as readily absorbed. The saved facts specify the L form.
Selenium Chemical Form
L-selenomethionine is an organic form regarded as readily absorbed in the evaluation.
Form Transparency & Isomer Specificity
The saved facts identify the L form of selenomethionine.

Dose, Safety & Label Transparency88

A serving contains 100 mcg of selenium, which is a moderate amount in the evaluation and falls below the evaluation’s upper boundary. Selenium from other sources contributes to total intake.
Dosage Efficacy Sweet Spot
The 100 mcg per serving is a moderate amount in the evaluation.
Safety Margin & UL Adherence
The 100 mcg per serving is below the evaluation’s upper boundary; selenium from food and other supplements contributes to total intake.

Value10

The selenium-normalized cost is high in the evaluation, although the price belongs to the complete product.
Price per 200 mcg Serving
The whole-product price works out to about $0.88 per 200 mcg of selenium.
B+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value
+2
A serving provides 15 mg zinc as citrate. The whole-product serving costs about $0.44.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

Zinc Citrate is viewed favorably for absorption in the evaluation.
Zinc Form Bioavailability
Zinc Citrate is viewed favorably for absorption in the evaluation.

Dose, Safety & Label Transparency61

The serving lists 15 mg zinc; the copper amount is unknown, so their balance cannot be assessed.
Elemental Dose Transparency
The label states 15 mg of elemental zinc per serving and names its source.
Zinc Dosage Safety & Effectiveness
The serving provides a moderate 15 mg of zinc.
Zinc-to-Copper Mineral Balance
The copper amount is unknown, so the zinc-to-copper balance cannot be assessed.

Value60

The whole-product serving costs about $0.44.
Price Per Serving Efficiency
The whole-product serving costs about $0.44.
B+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
A serving provides 500 mg of vitamin C as buffered calcium ascorbate. The whole product costs about $0.88 per gram of vitamin C.
How this ingredient is rated

Active Ingredient Quality & Bioavailability83

The vitamin C comes from calcium ascorbate, a buffered mineral form.
Vitamin C Chemical Form & Delivery System
The vitamin C form is calcium ascorbate.
Gastric Comfort & pH Balance
Calcium Ascorbate is a buffered mineral form.

Dose, Safety & Label Transparency91

A serving provides 500 mg of vitamin C.
Optimal Dosage Targeting
A serving provides 500 mg of vitamin C.
Purity & Excipient Quality
No evaluated artificial colors, preservatives or sweetening ingredients are recorded.
Mineral & Source Transparency
Vitamin C and product calcium amounts are recorded; not all of the calcium necessarily comes from calcium ascorbate.

Value20

The whole product costs about $0.88 per gram of vitamin C.
Price per Gram of Vitamin C
The whole product costs about $0.88 per gram of vitamin C.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledEveryday Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledEveryday Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledEveryday Health Eye Health forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsEveryday Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledEveryday Health forSelenium
  6. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledEveryday Health forVitamin C
  7. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEveryday Health forVitamin C
  8. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsEveryday Health forVitamin C
  9. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsEveryday Health forVitamin C
  10. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsEveryday Health forVitamin C
  11. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsEveryday Health forZinc
  12. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsEveryday Health forZinc
  13. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsEveryday Health forZinc
  14. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsEveryday Health forZinc
  15. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsEveryday Health forZinc
  16. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
    Watson SL; Jones LW; Stapleton F; Hinds M; Ng A; Tan J; Alster Y; Bosworth C; Rafaeli O; DePuy V; CELESTIAL STUDY Group · The ocular surface · 2026
    Randomized trial245 participantsEye Health forSelenium
  17. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
    Downie LE; Craig JP; Stapleton F; Tan J; Jones LW; Ng A; Hinds M; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial245 participantsEye Health forSelenium
  18. AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
    Stapleton F; Hinds M; Tan J; Jones L; Chalmers R; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial67 participantsEye Health forSelenium
  19. The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
    Stapleton F; Jia T; DePuy V; Bosworth C; Gleeson M; Tan J · The ocular surface · 2025
    Randomized trial14 participantsEye Health forSelenium
  20. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
    Berson EL; Rosner B; Sandberg MA; Hayes KC; Nicholson BW; Weigel-DiFranco C; Willett W · Archives of ophthalmology (Chicago, Ill. : 1960) · 1993
    Randomized trial601 participantsEye Health forVitamin A