CoQ-10 400 mg

CoQ-10 400 mg

The Vitamin Shoppe4.9 (78 ratings)
Format:Softgel Quantity: 30 Softgel(s) · 30 servings
Goals
$24.99 $0.83 per serving
iHerb$24.99

Product analysis

45 out of 100

CoQ-10 400 mg offers possible support for blood-vessel function, although the evidence depends on the person and preparation. Its form is not specified, making comparison with particular researched preparations harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The CoQ10 form is unspecified. That limits a close comparison with products that identify their particular preparation.

Ingredient Transparency63

The CoQ10 amount is stated, making serving comparisons easier. Its form is not disclosed.

Value For Money20

The full serving cost offers limited value for CoQ10. The unspecified preparation also makes close comparison with other forms harder.

Customer Satisfaction75

Customer ratings are favorable, though the number of buyers is modest. They describe satisfaction rather than proving effectiveness or safety.

Product Focus73

Possible blood-vessel support is more relevant than a promise of faster metabolism or longer life. The unspecified form limits comparison with specific preparations used for fatigue or other outcomes.

Format
Softgel
Container
30 Softgel(s)
Per serving
$0.83
Customer rating
4.9 · 78 ratings
Report analysis

Goals

Energy
Energy
Impact
Moderate effect
A Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Heart Health
Heart Health
Impact
High effect
B Ingredient FitD PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Metabolism Support
Metabolism Support
Impact
High effect
A Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Longevity
Longevity
Impact
Moderate effect
A Ingredient FitD- PathwaysF EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Inflammation
Inflammation
Impact
Highest effect
A- Ingredient FitD+ PathwaysA EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence

Ingredients

IngredientAmount per servingScore
Coenzyme Q-10
400 mg 26
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 · 400 mg OverallScore26
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value
The serving supplies 400 mg of CoQ10 at a high cost per serving. The CoQ10 form is unspecified, so form-specific comparisons are unclear. An additive of concern is flagged, but its identity is unavailable.
How this ingredient is rated

Active Ingredient Quality & Bioavailability12

The CoQ10 form is unspecified, so form-specific comparisons are unclear. The available information does not establish a specified absorption-enhancing formulation or black pepper extract.
Molecular Form: Ubiquinol vs. Ubiquinone
The CoQ10 form is unspecified, so form-specific comparisons are unclear.
Formulation & Absorption Enhancers
The available information does not establish a specified absorption-enhancing formulation or black pepper extract.

Dose, Safety & Label Transparency42

The serving provides 400 mg of CoQ10 but its form is unknown. The amount is stated, but an additive of concern is flagged; its identity is not specified in the available information.
Clinical Dosage Alignment
The serving provides 400 mg of CoQ10 but its form is unknown.
Label Transparency & Fillers
The amount is stated, but an additive of concern is flagged; its identity is not specified in the available information.

Value20

The cost per serving is high.
Price Per Effective Serving
The cost per serving is high.
View ingredientView products
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
Reduced ubiquinol at 200 mg in a softgel combines a readily absorbed form with a substantial amount for targeted use. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and uses reduced ubiquinol instead of the original's conventional or unspecified form, giving a well-specified option for the same CoQ10 goals.
85 Performance

Mega Ubiquinol CoQ10 100 mg

Qunol
Reduced ubiquinol at 100 mg in a softgel provides a clearly stated maintenance amount, while the small fat-soluble vitamin C addition contributes limited extra value. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and uses reduced ubiquinol instead of the original's conventional or unspecified form, giving a well-specified option for the same CoQ10 goals.
87 Performance

QH-absorb 100 mg

Jarrow Formulas
Reduced ubiquinol at 100 mg provides a clearly stated maintenance amount, while CoQ10 may reduce warfarin's anticoagulant effect. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and uses reduced ubiquinol instead of the original's conventional or unspecified form, giving a well-specified option for the same CoQ10 goals.
86 Budget

CoQ10 100 mg

Lake Avenue Nutrition
A clearly identified 100 mg ubiquinone amount offers focused CoQ10 support, though the dry capsule lacks a listed lipid carrier. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and retains a conventional ubiquinone form, while lowering recurring cost.
85 Budget

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best
A 100 mg ubiquinone amount with 5 mg of piperine targets absorption, but the dry capsule lacks a lipid carrier and piperine may alter the handling of some medicines. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and retains a conventional ubiquinone form, while lowering recurring cost.
84 Budget

CoQ10 100 mg

California Gold Nutrition
A 100 mg ubiquinone amount in a softgel supports uptake of the fat-soluble active, while CoQ10 may reduce warfarin's anticoagulant effect. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and retains a conventional ubiquinone form, while lowering recurring cost.
84 Value

CoQ10 100 mg

Best Naturals
A 100 mg ubiquinone amount provides focused CoQ10 support, though the dry capsule has no stated lipid carrier and CoQ10 may reduce warfarin response. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and retains a conventional ubiquinone form, while the lower recurring cost strengthens practical value.
83 Value

CoQ10 100 mg plus BioPerine

Lake Avenue Nutrition
A 100 mg ubiquinone amount in a softgel supports uptake, while 5 mg of black pepper extract may change exposure to some medicines. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and retains a conventional ubiquinone form, while the lower recurring cost strengthens practical value.
82 Value

CoQ10 100 mg wtih BioPerine

California Gold Nutrition
A 100 mg ubiquinone amount with 5 mg of piperine offers a focused formula, but the dry capsule lacks a lipid carrier and piperine may alter medicine exposure. Compared with the original, it uses a lower listed CoQ10 amount than the original's 400 mg and retains a conventional ubiquinone form, while the lower recurring cost strengthens practical value.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  7. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  8. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  9. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  10. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  11. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  12. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  13. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Support forCoenzyme Q-10
  14. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  15. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsInflammation forCoenzyme Q-10
  16. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsInflammation forCoenzyme Q-10
  17. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledInflammation forCoenzyme Q-10
  18. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledInflammation forCoenzyme Q-10
  19. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsInflammation forCoenzyme Q-10
  20. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewLongevity forCoenzyme Q-10