Vitamins D and K with Sea-lodine

Vitamins D and K with Sea-lodine

Life Extension4.8 (23,658 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$16.50 $0.27 per serving

Product analysis

71 out of 100

Vitamins D and K with Sea-lodine supports bone nutrition and provides iodine for normal thyroid function when intake is low. The vitamin K form is not clearly disclosed, which makes comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality50

Iodine has a favorable identified source, while vitamin D form quality cannot be compared confidently. Vitamin K lacks a clearly disclosed form, limiting a judgment from the label.

Ingredient Transparency88

All nutrient amounts are disclosed, so serving quantities can be compared. Vitamin D and iodine forms are named, while vitamin K is not clearly specified.

Value For Money67

Vitamin K offers favorable value, and iodine is also reasonably priced within the serving. Vitamin D cannot be compared reliably, leaving part of the price assessment uncertain.

Customer Satisfaction94

Customer ratings are very positive across a large review base. The volume gives a broad picture of satisfaction without establishing individual health effects.

Product Focus72

The short formula centers on bone nutrition, with iodine also relevant to low dietary intake. The large vitamin D serving does not establish stronger benefits or broader suitability.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.27
Customer rating
4.8 · 23,658 ratings
Report analysis

Goals

Heart Health
Impact
High effect
B- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin K · 2100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Energy
Impact
High effect
B+ Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 1000 mcgVitamin D · 125 mcg
Study evidence
Iodine Adverse 3 studies
Vitamin D Supportive 32 studies
Everyday Health
Impact
High effect
B- Ingredient FitC- PathwaysB+ EvidenceA Formulation Logic
Vitamin D · 125 mcgVitamin K · 2100 mcg
Study evidence
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Metabolism Support
Impact
High effect
B+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin D · 125 mcg
Study evidence
Iodine Mixed 17 studies
Vitamin D Supportive 65 studies
Bone Health
Impact
Highest effect
B- Ingredient FitB+ PathwaysA+ EvidenceA Formulation Logic
Vitamin K · 2100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Longevity
Impact
High effect
B Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Vitamin K · 2100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies

Ingredients

IngredientAmount per servingScore
Vitamin D3 (Cholecalciferol)
125 mcg
Vitamin K
2100 mcg 100
Iodine (Sea-Iodine Complex Blend)
1000 mcg 94
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value
Vitamin K · 2100 mcg OverallScore100
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  2. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  3. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  4. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  5. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  6. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  7. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  8. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  9. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  10. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  11. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  12. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  13. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  14. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  15. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  16. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  17. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  18. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  19. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledEveryday Health forVitamin D
  20. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsEveryday Health forVitamin D