Melatonin 3 mg

Melatonin 3 mg

NOW4.8 (4,588 ratings)
Format:Lozenge Quantity: 90 Liquid(s) · 90 servings
Goals
$4.65 $0.05 per serving

Product analysis

65 out of 100

Melatonin 3 mg offers an economical way to support sleep timing and may help you fall asleep sooner.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality27

The B6 form is identified, while the melatonin form is not. There is not enough information for a firm quality judgment about both ingredients.

Ingredient Transparency81

Both ingredient amounts are disclosed, allowing serving comparisons. The melatonin form remains unidentified.

Value For Money78

Melatonin has a low cost per serving. There is not enough information to judge the added B6 contribution to value.

Customer Satisfaction91

Customer feedback is favorable across thousands of reviews. The broad review base makes the satisfaction pattern less dependent on a few opinions.

Product Focus76

Sleep timing is the clearest purpose of the formula. Its usefulness depends on when it is taken, with no universal ideal amount established.

Format
Lozenge
Container
90 Liquid(s)
Per serving
$0.05
Customer rating
4.8 · 4,588 ratings
Report analysis

Goals

Sleep Support
Impact
Highest effect
A+ Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Melatonin · 3 mg
Study evidence
Melatonin Supportive 181 studies
Brain Health
Impact
Moderate effect
A+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Vitamin B6 · 3 mg
Study evidence
Melatonin Supportive 29 studies
Vitamin B6 Supportive 29 studies
Immunity
Impact
High effect
A+ Ingredient FitD PathwaysB EvidenceA+ Formulation Logic
Study evidence
Melatonin Supportive 10 studies

Ingredients

IngredientAmount per servingScore
Vitamin B6 (Pyridoxine Hydrochloride)
3 mg
Melatonin
3 mg 68
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Melatonin · 3 mg OverallScore68
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 3 mg of melatonin at a low cost per serving. It carries a GMP claim, but no independent finished-batch testing claim is available.
How this ingredient is rated

Active Ingredient Quality & Bioavailability20

It carries a GMP claim, but no independent finished-batch testing claim is available.
Third-Party Purity Verification
A GMP claim is present, but no independent finished-batch testing claim is available.

Dose, Safety & Label Transparency100

Each serving provides 3 mg of melatonin.
Physiological Dosing Alignment
The serving contains 3 mg of melatonin.

Value100

The cost per serving is low.
Price Per Serving Efficiency
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  2. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  3. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  4. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  5. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  6. Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
    Zhang C; Luo J; Yuan C; Ding D · Journal of Alzheimer's disease : JAD · 2021
    Meta-analysis21 studies pooledBrain Health forVitamin B6
  7. Relationship between serum pyridoxal 5'-phosphate concentration and cognitive function in older Japanese.
    Itoh K; Kuwabara A; Otsuka R; Sugimoto T; Sakurai T; Niida S; Ao M; Tanaka K; Takenaka S; Kanouchi H · Journal of clinical biochemistry and nutrition · 2025
    Cross-sectional study266 participantsBrain Health forVitamin B6
  8. A randomized, controlled trial to evaluate the efficacy of pyridoxine and ascorbic acid on cognitive function and quality of life in post-menopausal women.
    Dhivya K; Sarumathy S; Manigandan G · Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Randomized trial180 participantsBrain Health forVitamin B6
  9. Lower Plasma Vitamin B-6 is Associated with 2-Year Cognitive Decline in the Boston Puerto Rican Health Study.
    Palacios N; Scott T; Sahasrabudhe N; Gao X; Tucker KL · The Journal of nutrition · 2020
    Cohort study949 participantsBrain Health forVitamin B6
  10. Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
    Iolascon G; Gimigliano R; Bianco M; De Sire A; Moretti A; Giusti A; Malavolta N; Migliaccio S; Migliore A; Napoli N; Piscitelli P; Resmini G; Tarantino U; Gimigliano F · The journal of nutrition, health & aging · 2017
    Scoping review12 studies pooledBrain Health forVitamin B6
  11. Exogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity.
    Oda K; Danko J; Villasante E; Bergmann-Leitner E; Lee R; Wijayalath W · Frontiers in immunology · 2025
    Randomized trialImmunity forMelatonin
  12. Evaluation of melatonin effectiveness in the adjuvant treatment of ulcerative colitis.
    Chojnacki C; Wisniewska-Jarosinska M; Walecka-Kapica E; Klupinska G; Jaworek J; Chojnacki J · Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · 2012
    Randomized trial60 participantsImmunity forMelatonin
  13. Pineal-opioid system interactions in the control of immunoinflammatory responses.
    Lissoni P; Barni S; Tancini G; Fossati V; Frigerio F · Annals of the New York Academy of Sciences · 1995
    Clinical trial130 participantsImmunity forMelatonin
  14. Influenza vaccine response is predicted by chronotype and differentially associated with pre- and post-vaccination sleep.
    Harrison EM; Lee RU; Porter CK; Isidean SD; Easterling AP; White L; Boulifard DA; DeTizio K; Liang Z; Sedegah M; Danko J; Glickman GL · Brain, behavior, & immunity - health · 2026
    Randomized trialImmunity forMelatonin
  15. Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality.
    Tan DX; Reiter RJ · Life sciences · 2022
    Narrative review19 participantsImmunity forMelatonin
  16. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  17. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  18. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  19. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  20. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin