Iron Complex

Iron Complex

Advanced Nutrition by Zahler4.8 (10,836 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals

Product analysis

64 out of 100

Iron Complex supplies nutrients involved in normal blood formation and may help tiredness linked to low nutrient intake. Its practical benefit depends on whether a nutritional shortage is the cause.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality38

Histidine has a favourable identified form, while folate is unspecified. The other named forms do not by themselves establish a clear quality advantage.

Ingredient Transparency93

Ingredient amounts are listed, and most forms are identified. Folate is unspecified, while differing iron details leave its useful amount less clear for some purposes.

Value For Money52

Iron offers favourable value at the full serving cost, while histidine is more moderate. Folate offers limited value, and vitamin C and B12 remain uncertain.

Customer Satisfaction92

Customer feedback is very positive. More than ten thousand ratings provide an extensive base for judging satisfaction.

Product Focus67

The formula centres on nutrients involved in blood formation and shortage-related tiredness. Expected benefit depends on nutritional need, and the iron amount is not consistently clear across purposes.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.16
Customer rating
4.8 · 10,836 ratings
Report analysis

Goals

Hair Health
Impact
Moderate effect
C Ingredient FitF PathwaysB EvidenceA Formulation Logic
Iron · 25 mgVitamin C · 60 mg
Study evidence
Folate Mixed 15 studies
Iron Disputed 25 studies
Energy
Impact
High effect
A- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin B12 · 80 mcgIron · 25 mg
Study evidence
Iron Supportive 74 studies
Productivity Boost
Impact
Moderate effect
B Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Iron · 25 mgVitamin B12 · 80 mcgVitamin B12 · 80 mcg
Study evidence
Iron Supportive 69 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Ascorbic Acid)
60 mg
Vitamin B12 (Methylcobalamin)
80 mcg
Folic Acid
400 mcg 54
Ferrochel (Iron)
25 mg 96
L-Histidine (L-Histidine Hydrochloride)
100 mg 63
Gluten Free Adults 18–50 Kosher Dairy Free
Report overview
Iron · 25 mg OverallScore96
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
A serving provides 25 mg iron at a modest cost per serving. Iron comes from ferrous bisglycinate. It includes 60 mg vitamin C, which supports iron absorption, plus vitamin B12 and folate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

Iron comes from ferrous bisglycinate. It includes 60 mg vitamin C, which supports iron absorption, plus vitamin B12 and folate.
Iron Chemical Form & Bioavailability
Iron comes from ferrous bisglycinate.
Absorption Support & Blocker Avoidance
It includes 60 mg vitamin C, which supports iron absorption, plus vitamin B12 and folate.

Dose, Safety & Label Transparency100

The stated serving provides 25 mg iron.
Elemental Iron Label Clarity
The iron amount per serving is stated.
Dosage Effectiveness & Safety Range
A serving provides 25 mg iron.

Value80

The cost per serving is modest.
Price per Effective Serving
The cost per serving is modest.
C+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyD+ Value
A serving lists 100 mg of histidine at a moderate estimated cost per 500 mg. The estimate assigns the full product cost to histidine and may overstate its cost. The source is L-Histidine Hydrochloride.
How this ingredient is rated

Active Ingredient Quality & Bioavailability67

The source is L-Histidine Hydrochloride. A good manufacturing practices (GMP) claim is noted, but independent testing is not documented.
Histidine Isomer & Chemical Form
The source is L-Histidine Hydrochloride.
Sourcing & Purity Standards
A good manufacturing practices (GMP) claim is noted, but independent testing is not documented.

Dose, Safety & Label Transparency65

A serving lists 100 mg of histidine. The amount and source are stated.
Histidine Dose by Declared Basis
A serving lists 100 mg of histidine.
Transparency & Label Disclosure
The amount and source are stated.

Value50

The estimated cost per 500 mg of histidine is moderate; assigning the full product cost to histidine may overstate its cost.
Price per 500 mg of Declared Histidine Basis
The estimated cost per 500 mg of histidine is moderate; assigning the full product cost to histidine may overstate its cost.
Folate · 400 mcg OverallScore54
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
It supplies 400 mcg of folate per serving. The cost per serving is relatively low. The folate comes from folic acid, which needs conversion to the active form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability14

It uses folic acid, which needs conversion to the active form. The available information identifies no branded source or active-isomer claim.
Folate Form Hierarchy
It uses folic acid, which needs conversion to the active form.
Patented Sources & Isomeric Purity
The available information identifies no branded source or active-isomer claim.

Dose, Safety & Label Transparency100

It provides 400 mcg of folate per serving; the folic acid amount corresponds to 680 mcg DFE by the labeling conversion.
Folate Dosage by Declared Basis
It provides 400 mcg of folate per serving; the folic acid amount corresponds to 680 mcg DFE by the labeling conversion.

Value40

The cost per serving is relatively low.
Price per Bioavailable Serving
The cost per serving is relatively low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  2. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  3. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  4. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  5. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  6. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  7. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  8. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  9. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  10. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  11. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  12. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate Hair Health forVitamin B12
  13. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  14. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  15. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  16. The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
    Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
    Case-control study100,203 participantsHair Health forIron
  17. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
    Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
    Meta-analysis10,029 participants36 studies pooledHair Health forIron
  18. Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
    Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
    Cohort study261 participantsHair Health forIron
  19. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
    Cross-sectional study100 participantsHair Health forIron
  20. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
    Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
    Cohort study155 participantsHair Health forIron