PreNatal with Folic Acid

PreNatal with Folic Acid

21st Century4.8 (8,393 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$4.63 $0.07 per serving

About this product

Iron, folate and B12 make blood-forming nutrient support the clearest role. Iron at 28 mg can help fill higher nutritional needs, while these nutrients may help with tiredness linked to low intake rather than providing extra energy when needs are met.

The iron source is clearly identified as ferrous fumarate, but it can be harder on the stomach. The same serving contains 25 mg of zinc, which can compete with iron absorption, and zinc oxide is a less favorable form for absorption.

The low serving cost makes the iron and zinc contributions affordable, but the prenatal name does not establish complete pregnancy nutrition. Iodine, choline and DHA are not listed in the supplied ingredients, and the ingredient details do not identify folate's form despite folic acid appearing in the title.

Who is it for
  • People planning pregnancy or pregnant who need an iron-containing vitamin and are checking their full nutrient plan
  • Adults with a specific need for additional iron rather than routine iron supplementation
Best for
  • Iron and folate intake support
  • Blood-forming nutrients when dietary intake is low

Pros

  • Iron, folate and B12 provide related blood-forming nutrients
  • Ferrous fumarate and its amount are clearly identified
  • Low serving cost supports value for the stated iron contribution

Cons

  • Zinc oxide has less favorable absorption potential
  • Iron and zinc in the same serving can compete for absorption
  • Iodine, choline and DHA are not listed
  • Folate's precise form is missing from the ingredient details

Warnings

  • Ferrous fumarate at 28 mg may be harder on the stomach, which matters if iron supplements have caused discomfort before.
  • The substantial iron serving is intended for higher needs; adding another iron supplement should be based on an assessed need.
  • The 25 mg zinc serving adds to food and other supplements; avoid automatically combining it with a separate high-dose zinc product.

Product analysis

64 out of 100

PreNatal with Folic Acid may help fill gaps in folate, iron and other nutrients involved in normal blood formation and energy use. Its clearly listed amounts and mostly named forms make it easier to compare with similar supplements.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality36

Most ingredient forms are named, but their quality cannot all be judged confidently. Zinc oxide is a less favorable choice for absorption, and the folate form is not specified.

Ingredient Transparency97

Clear amounts and mostly named forms make the label easy to compare. The folate form is the main missing detail.

Value For Money53

Iron and zinc offer favorable value at the full serving cost. The value of the remaining nutrients is less certain.

Customer Satisfaction92

Customer ratings are very positive. The large number of ratings gives this feedback a broad base, although ratings do not establish effectiveness.

Product Focus62

The nutrients may help with normal immune function, blood formation and deficiency-related tiredness. Those benefits depend on nutritional need, and the prenatal name alone does not establish pregnancy-specific outcomes.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.07
Customer rating
4.8 · 8,393 ratings
Report analysis

Goals

Everyday Health
Impact
Highest effect
A Ingredient FitA+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 1334 mcg DFEVitamin B12 · 8 mcgVitamin D · 10 mcgZinc · 25 mgVitamin C · 120 mg
Study evidence
Folate Supportive 80 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 10 mcgRiboflavin · 1.7 mgThiamin · 1.8 mgVitamin B12 · 8 mcgIron · 28 mg
Study evidence
Iron Supportive 74 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Immunity
Impact
Highest effect
B- Ingredient FitB PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 120 mgZinc · 25 mgVitamin A · 1200 mcgVitamin D · 10 mcg
Study evidence
Iron Supportive 23 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Hair Health
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 10 mcgZinc · 25 mgIron · 28 mgVitamin C · 120 mg
Study evidence
Folate Mixed 15 studies
Iron Disputed 25 studies
Niacin Disputed 2 studies
Vitamin A Disputed 13 studies
Vitamin D Disputed 34 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Productivity Boost
Impact
High effect
C+ Ingredient FitD PathwaysA EvidenceA+ Formulation Logic
Iron · 28 mgVitamin B12 · 8 mcgVitamin B12 · 8 mcgVitamin B6 · 2.6 mgZinc · 25 mg
Study evidence
Iron Supportive 69 studies
Zinc Supportive 11 studies
Skin Health
Impact
High effect
C+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Zinc · 25 mgVitamin C · 120 mgVitamin E · 13.5 mg
Study evidence
Niacin Supportive 61 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Testosterone Support
Impact
Moderate effect
C- Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Zinc · 25 mgVitamin D · 10 mcg
Study evidence
Vitamin D Supportive 56 studies
Vitamin E Disputed 3 studies
Zinc Disputed 7 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene)
1200 mcg
Vitamin C (Ascorbic Acid)
120 mg
Vitamin D3 (Cholecalciferol)
10 mcg
Vitamin E (DL-Alpha-Tocopheryl Acetate)
13.5 mg
Thiamine (Thiamine Mononitrate)
1.8 mg
Riboflavin
1.7 mg
Niacin (Niacinamide)
20 mg
Vitamin B6 (Pyridoxine Hydrochloride)
2.6 mg
Folate
1334 mcg DFE
Vitamin B12 (Cyanocobalamin)
8 mcg
Calcium (Calcium Carbonate)
200 mg
Iron (Ferrous Fumarate)
28 mg 73
Zinc (Zinc Oxide)
25 mg 55
Gluten Free Pregnant Women 18–50
Report overview
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
The serving provides 28 mg iron at a low cost per serving. The iron comes from ferrous fumarate. Its zinc may compete with iron absorption.
How this ingredient is rated

Active Ingredient Quality & Bioavailability31

The iron comes from ferrous fumarate. Zinc is also present and can compete with iron absorption. It also includes 120 mg vitamin C, B12 and folate.
Iron Chemical Form & Bioavailability
The iron comes from ferrous fumarate.
Absorption Support & Blocker Avoidance
Zinc is also present and can compete with iron absorption. It also includes 120 mg vitamin C, B12 and folate.

Dose, Safety & Label Transparency100

The label states 28 mg elemental iron per serving.
Elemental Iron Label Clarity
The label states 28 mg elemental iron per serving.
Dosage Effectiveness & Safety Range
The serving provides 28 mg iron.

Value100

The cost per serving is low.
Price per Effective Serving
The cost per serving is low.
F Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 25 mg of zinc at a low cost per serving. It uses Zinc Oxide, and the amount is substantial. The copper amount is unknown, leaving the mineral balance unclear.
How this ingredient is rated

Active Ingredient Quality & Bioavailability20

The zinc comes from Zinc Oxide.
Zinc Form Bioavailability
The zinc comes from Zinc Oxide.

Dose, Safety & Label Transparency67

The label states 25 mg of zinc per serving, a substantial amount. The copper amount is unknown, so the zinc-to-copper balance is unclear.
Elemental Dose Transparency
The label states 25 mg of zinc and names a source.
Zinc Dosage Safety & Effectiveness
The 25 mg per serving is a substantial amount.
Zinc-to-Copper Mineral Balance
The copper amount is unknown, so the zinc-to-copper balance is unclear.

Value100

The cost per serving is low.
Price Per Serving Efficiency
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  2. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  3. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  4. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  5. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  6. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  7. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  8. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  9. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  10. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  11. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  12. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  13. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  14. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  15. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  16. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  17. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  18. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  19. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  20. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12