B-50

B-50

NOW4.7 (34,420 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals

Product analysis

70 out of 100

B-50 can help fill B-vitamin gaps involved in normal energy use and blood-cell formation. Benefits for tiredness depend on low intake being the cause.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Several B vitamins use favorable forms, and B6 and niacin forms are clearly identified. Riboflavin is a less favorable form choice, while some other forms remain unspecified or uncertain.

Ingredient Transparency86

All listed amounts and most B-vitamin forms are disclosed. Folate, biotin and some other forms remain unspecified, limiting detailed comparison.

Value For Money60

Riboflavin, niacin and B6 offer good value for the serving price. Vitamin B5 and choline offer weaker value, and several other comparisons remain uncertain.

Customer Satisfaction92

Customer ratings are generally positive. A large number of ratings gives a broader picture of customer satisfaction.

Product Focus66

The formula centers on B-vitamin nutrition for normal metabolism and energy use. Higher amounts do not establish more energy or increased calorie burning once needs are met.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.08
Customer rating
4.7 · 34,420 ratings
Report analysis

Goals

Impact
High effect
A- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

The B vitamins support normal energy metabolism, while folate supports blood cell formation. Addressing low intake of riboflavin, niacin, folate, B6 or B5 can help with associated tiredness. Higher amounts do not establish extra energy when intake is adequate. The supplied B12 amount is below the saved calculation’s inclusion threshold, which does not mean it is nutritionally ineffective.

How this product is rated for Energy

Ingredient fit88

Six B vitamins contribute; B12 remains below the amount required for inclusion in the saved finding.
Goal fit
Six B vitamins contribute; B12 remains below the amount required for inclusion in the saved finding.
Dose adequacy
The included ingredient amounts are fully or substantially recognized; this does not establish extra benefit above nutritional adequacy.

Pathways0

The B-vitamin contribution concerns nutrient sufficiency rather than the five evaluated energy routes.
Depth
None of the five evaluated energy routes receives coverage; nutrient sufficiency is handled separately.
Breadth
No evaluated route reaches the required coverage level.

Evidence78

Riboflavin leads the evidence finding, and all six included ingredients match studied preparations.
Evidence strength
Vitamin B2 (Riboflavin) leads the saved evidence finding, subject to the specific limitations described above.
Studied preparation
Riboflavin leads the evidence finding, and all six included ingredients match studied preparations.

Formulation logic100

The included ingredients do not require an unmet partner, and no configured conflict was detected.
Partner coverage
No required partner is missing for the included ingredients.
Conflicts
No configured ingredient conflict was detected.
Effective doses
All 6 included ingredients meet the saved minimum amount threshold; that threshold does not prove fatigue relief.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

B vitamins help normal energy-yielding metabolism, but extra intake has not been shown here to raise whole-body calorie expenditure above adequate nutrition. Their declared amounts receive saved contributions without establishing a direct thermogenic effect or sustained weight loss.

How this product is rated for Metabolism Support

Ingredient fit81

The saved findings count nutrient amounts, principally B vitamins. Normal energy metabolism does not establish an increase in calorie expenditure.
Goal fit
Other actives broaden the formula beyond this goal, reducing its focus.
Dose adequacy
The known amounts provide partial support in the saved comparison, without establishing a proven thermogenic dose.

Pathways0

No configured thermogenic function receives a contribution from these ingredients.
Depth
No configured thermogenic function receives a contribution.
Breadth
No function reaches the saved breadth threshold.

Evidence100

Vitamin B1 (Thiamin) is the strongest saved evidence contributor. The supplied scientific context does not establish a routine increase in calorie expenditure.
Evidence strength
Vitamin B1 (Thiamin) supplies the strongest saved evidence contribution; this does not override limitations in the direct energy-expenditure findings.
Studied preparation
The counted amounts match preparations accepted in the saved comparison.

Formulation logic100

The counted ingredients can contribute independently and no configured conflict is found. Their known amounts pass the saved minimum.
Partner coverage
The counted ingredients can contribute independently or have the required partner.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
The counted amounts pass the saved minimum, which does not establish a proven increase in energy expenditure.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
50 mg 76
Riboflavin
50 mg 72
Niacin (Niacinamide)
50 mg 81
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
50 mcg
Pantothenic Acid (Calcium Pantothenate)
50 mg 70
Choline (Choline Bitartrate)
25 mg 50
PABA
25 mg 84
Inositol
25 mg
Gluten Free Adults 18–50 Vegan Kosher Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 50 mg of niacin as niacinamide, a form that generally does not cause flushing. The whole-product serving costs about $0.08.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The niacin comes as niacinamide, a standard form of vitamin B3.
Niacin Form & Goal Alignment
Niacinamide is a standard vitamin B3 form used for general nutrition.
Precursor Source Quality
The saved facts identify standard niacinamide as the niacin source.

Dose, Safety & Label Transparency67

The niacin amount and niacinamide form are identified: 50 mg per serving.
Clarity of Chemical Form
The saved facts identify the niacin form as niacinamide.
Form-Specific Dosage Efficacy
Each serving provides 50 mg of niacin as niacinamide.
Flush Risk & Safety Labeling
Niacinamide generally does not cause the flushing associated with nicotinic acid; no no-flush claim is recorded in the saved facts.

Value100

The whole-product price is about $0.08 per serving.
Price Per Effective Serving
A whole-product serving costs about $0.08; that price includes the rest of the product, not just niacin.
PABA · 25 mg OverallScore84
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
Each serving lists 25 mg of PABA. The whole-product price works out to about $0.32 per 100 mg of PABA.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

PABA is named; a specific purity grade is not recorded in the saved facts.
PABA Source & Grade
PABA is named; a specific purity grade is not recorded in the saved facts.

Dose, Safety & Label Transparency95

The PABA amount is individually stated as 25 mg per serving. None of the three checked additive categories are recorded in the saved ingredient information: artificial dyes, titanium dioxide, or hydrogenated oils.
PABA Dosage Alignment
25 mg per serving falls in the evaluation's B-complex amount category.
Label Disclosure Clarity
The PABA amount is individually stated as 25 mg per serving.
Additive and Excipient Quality
None of the three checked additive categories are recorded in the saved ingredient information: artificial dyes, titanium dioxide, or hydrogenated oils.

Value70

The whole-product price works out to about $0.32 per 100 mg of PABA.
Price per 100mg PABA
The whole-product price works out to about $0.32 per 100 mg of PABA.
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
One serving contains 50 mg of vitamin B6, exceeding the European adult daily upper limit. The identified source is pyridoxine hydrochloride; total intake also depends on food and other supplements.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 source is identified as pyridoxine hydrochloride; the assessment does not imply that it absorbs better than other forms.
Vitamin B6 Form Identification
The B6 source is identified as pyridoxine hydrochloride; that identification does not establish an absorption advantage.
Clean Label and Excipient Purity
No dyes, titanium dioxide or hydrogenated oils, or talc are flagged in the saved ingredient evidence; this does not prove the product is additive-free.

Dose, Safety & Label Transparency37

The 50 mg of B6 in one serving exceeds the European adult daily upper limit; total intake also includes food and other supplements. The source is identified.
Vitamin B6 Dose & Safety Policy
The 50 mg of B6 in one serving exceeds the European adult daily upper limit; total intake also includes food and other supplements.
Label Transparency
The saved label information identifies pyridoxine hydrochloride as the B6 source.

Value100

The whole-product price is about $0.0016 per mg of B6, relatively low for B6. The price is for the whole product.
Vitamin B6 Price Efficiency
The whole-product price is about $0.0016 per mg of B6, relatively low for B6. The price is for the whole product.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin