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Concentrated Ultra Prostagen

Metagenics
4.7
★ ★ ★ ★ ★
(37 ratings)
Glutamic Acid 50 mg
Stinging Nettle 100 mg
Glycine 50 mg
Alanine 50 mg
Saw Palmetto 320 mg
Lycopene 2 mg
Product Image
Score80

A focused saw-palmetto and nettle capsule is practical, though lycopene and amino-acid support remain light.

How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Hair Health
Testosterone Support
Anti-Inflammatory Support

Score 80

A focused saw-palmetto and nettle capsule is practical, though lycopene and amino-acid support remain light.

How scoring works
$59.95($0.99 per serving)
iHerb
$ 62.95
iHerb
$ 62.95
Pure Formulas
$ 59.95
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Analysis

Saw palmetto at 320 mg is identified by fatty acids and sterols, giving the main ingredient useful quality context. A 100 mg 10:1 nettle root extract broadens the prostate-focused approach.

Zinc, vitamin D, vitamin B6, and 2 mg lycopene provide supporting nutrients. Glycine, alanine, and glutamic acid are each only 50 mg and are unlikely to drive results.

The one-capsule, 60-serving format is convenient for regular use. It fits prostate and possibly hair-related support better than direct testosterone or broad inflammation goals.

Who is it for
  • Adult men seeking prostate-oriented botanicals
  • Users wanting one capsule daily
  • People seeking standardized saw palmetto
Best for
  • Prostate-support routines
  • Combining saw palmetto and nettle
  • Longer 60-serving use

Pros

  • Provides 320 mg standardized saw palmetto
  • Uses concentrated nettle root
  • One-capsule serving
  • Includes zinc and vitamin D

Cons

  • Only 2 mg lycopene
  • Amino acids are lightly dosed
  • Indirect testosterone support
  • Limited anti-inflammatory breadth

Warnings

  • Saw palmetto can interact with anticoagulant therapy
  • The formula may affect hormone-related management and should be reviewed before use with related medicines
  • Designed for adult men and not appropriate during pregnancy

Nutrient quality

89 Highest impact

Standardized saw palmetto, concentrated nettle, and zinc citrate provide strong form quality. Core prostate ingredients are meaningful, while lycopene and amino acids play smaller supporting roles.

.

Ingredient transparency

83 Highest impact

Every active amount is individually disclosed without a hidden blend. Complete directions and inactive ingredients are not supplied.

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Customer satisfaction

64 Moderate impact

The supplied average rating is strong. The rating base is modest and limits confidence in the average, but no detailed experience evidence was supplied.

.

Value for money

80 Highest impact

Serving economics are favorable. Formula quality supports the asking price well.

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Report analysis

Goals

Hair Health
Hair Health
Impact
High effect
B Goal FitB Strength of SupportC CoverageB+ Formula Quality
Vitamin D · 5 mcgZinc · 7.5 mg

Saw palmetto directly targets androgen signaling that may contribute to patterned hair thinning. The daily extract amount matches common use, but fatty-acid and sterol standardization is not quantified.

Zinc, vitamin D, nettle, and amino acids add limited secondary support. Saw palmetto is inappropriate during pregnancy and warrants caution with hormonal therapies or anticoagulants.

Study evidence
Saw Palmetto Supportive 5 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
C Goal FitC Strength of SupportC- CoverageB- Formula Quality
Zinc · 7.5 mgVitamin D · 5 mcg

Stinging nettle root, zinc, and vitamin D provide some relevance to free-testosterone availability and hormone production. The prostate formula is more strongly oriented toward urinary function and DHT metabolism.

A concentrated nettle extract is a useful detail, but zinc and vitamin D are below targeted endocrine amounts. Saw palmetto and other prostate ingredients create a coherent prostate product without building a strong testosterone formula.

Study evidence
Vitamin D Supportive 56 studies
Zinc Disputed 7 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC- CoverageC- Formula Quality
Vitamin D · 5 mcgGlycine · 50 mg

Stinging nettle root, glycine, and lycopene touch histamine, cytokine, and antioxidant pathways, but the formula is designed mainly for prostate support. Glycine and lycopene are present at small amounts for a focused anti-inflammatory purpose.

Saw palmetto dominates the formula without serving as a broad anti-inflammatory anchor. Several individually disclosed amounts improve transparency, but pathway depth remains weak.

Study evidence
Glycine Supportive 7 studies
Lycopene Supportive 15 studies
Stinging Nettle Supportive 5 studies

Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
 5 mcg
Vitamin B6 (Pyridoxine Hydrochloride)
 10 mg
Zinc (Zinc Citrate)
 7.5 mg
Saw Palmetto Berry Extract (fatty acids and sterols)
 320 mg
Stinging Nettle (Urtica dioica) root 10:1 extract
100 mg
Glycine
50 mg
L-Alanine
50 mg
L-Glutamic Acid
50 mg
Lycopene
2 mg
Gluten Free Men 18–50
Report overview
Glutamic Acid · 50 mg OverallScore76
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

The prostate-support formula uses the clearly identified L-form in an appropriate free-form role. Its 50 mg amount is useful and fully disclosed, though smaller than a dedicated amino acid serving. A very high serving cost weakens value despite the broader botanical formula.

View ingredientView products
Stinging Nettle · 100 mg OverallScore70
A+ Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyD+ Value

A clearly specified root source and high-ratio extract provide strong prostate-oriented quality. The listed extract amount is modest, although concentration improves its likely depth. The elevated serving cost produces fair value for a premium form rather than broad dose efficiency.

View ingredientView products
Glycine · 50 mg OverallScore67
C+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value

The glycine amount is minimal and serves only as a minor component of a prostate-support formula. Capsule delivery is convenient, but no premium glycine source is identified. Appropriately dosed saw palmetto and other actives support neutral value for the broader purpose, not for glycine.

View ingredientView products
Loading alternative details
77 Performance

Prostate Essentials Plus

Swanson
<p>Its label clearly provides 120 mg of Stinging Nettles 4:1 concentrate, making it a more clearly defined saw palmetto and stinging nettle and lycopene and glutamic acid option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s glycine and alanine coverage.</p>
80 Performance

Prostate Support

NOW
<p>Its label clearly provides 1 g of Total Fat, making it a more clearly defined saw palmetto and stinging nettle and lycopene option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s glycine and glutamic acid and alanine coverage.</p>
76 Performance

Ortho Prostate

Protocol For Life Balance
<p>Its label clearly provides 1 g of Total Fat, making it a more clearly defined saw palmetto and stinging nettle and lycopene option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s glycine and glutamic acid and alanine coverage.</p>
79 Budget

Gold Specifics Prostate Support

Solgar
<p>Its label clearly provides 10 mg of Zinc as Zinc Glycinate, preserving relevant saw palmetto and stinging nettle and lycopene coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s glycine and glutamic acid and alanine coverage.</p>
77 Budget

Prostate Essentials

Swanson
<p>Its label clearly provides 15 mg of Zinc as Zinc Picolinate, preserving relevant saw palmetto and stinging nettle and glutamic acid coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s lycopene and glycine and alanine coverage.</p>
69 Budget

Saw Palmetto With Lycopene

Natural Factors HerbalFactors
<p>Its label clearly provides 160 mg of Saw Palmetto extract, preserving relevant saw palmetto and lycopene coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s stinging nettle and glycine and glutamic acid and alanine coverage.</p>
63 Value

Prostabs Plus

Futurebiotics
<p>Its label clearly provides 173 mg of L-Glutamic Acid, keeping the formula relevant to lycopene and glycine and glutamic acid and alanine. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s saw palmetto and stinging nettle coverage.</p>
80 Value

Prostate Support

NOW
<p>Its label clearly provides 1 g of Total Fat, keeping the formula relevant to saw palmetto and stinging nettle and lycopene. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s glycine and glutamic acid and alanine coverage.</p>
78 Value

Herbal Prostate Complex

Swanson
<p>Its label clearly provides 562 mg of Saw Palmetto, keeping the formula relevant to saw palmetto and stinging nettle. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s lycopene and glycine and glutamic acid and alanine coverage.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes.
    Cruz M; Maldonado-Bernal C; Mondragón-Gonzalez R; Sanchez-Barrera R; Wacher NH; Carvajal-Sandoval G; Kumate J · Journal of endocrinological investigation · 2009
    Randomized trial74 participantsAnti-Inflammatory Support forGlycine
  2. Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial.
    Vargas MH; Del-Razo-Rodríguez R; López-García A; Lezana-Fernández JL; Chávez J; Furuya MEY; Marín-Santana JC · BMC pulmonary medicine · 2018
    Randomized trial13 participantsAnti-Inflammatory Support forGlycine
  3. Subgingival air polishing (glycine powder) versus minocycline hydrochloride: efficacy in residual periodontal pockets following endoscope-assisted scaling and root planing.
    Guo X; Bai H; Lu X; Guo J; Qi Y; Huo X; Li S · Clinical oral investigations · 2026
    Randomized trial80 participantsAnti-Inflammatory Support forGlycine
  4. Long-term Implant Maintenance: A Systematic Review of Home and Professional Care Strategies in Supportive Implant Therapy.
    Araújo TG; Moreira CS; Neme RA; Luan H; Bertolini M · Brazilian dental journal · 2024
    Systematic review13 studies pooledAnti-Inflammatory Support forGlycine
  5. Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration and study on the maintenance effect of subgingival sandblasting.
    Pan T; Meng W; Zhang M; Xie Y; Chen Z; Zhou M; Yin L; Xie H · BMC oral health · 2026
    Randomized trial198 participantsAnti-Inflammatory Support forGlycine
  6. Carotenoids supplementation and inflammation: a systematic review and meta-analysis of randomized clinical trials.
    Hajizadeh-Sharafabad F; Zahabi ES; Malekahmadi M; Zarrin R; Alizadeh M · Critical reviews in food science and nutrition · 2022
    Meta-analysis26 studies pooledAnti-Inflammatory Support forLycopene
  7. Effects of lycopene supplementation on oxidative stress and markers of endothelial function in healthy men.
    Kim JY; Paik JK; Kim OY; Park HW; Lee JH; Jang Y; Lee JH · Atherosclerosis · 2011
    Randomized trial126 participantsAnti-Inflammatory Support forLycopene
  8. Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals.
    McEneny J; Wade L; Young IS; Masson L; Duthie G; McGinty A; McMaster C; Thies F · The Journal of nutritional biochemistry · 2013
    Randomized trial54 participantsAnti-Inflammatory Support forLycopene
  9. Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: proof of concept.
    Wood LG; Garg ML; Powell H; Gibson PG · Free radical research · 2008
    Randomized trial32 participantsAnti-Inflammatory Support forLycopene
  10. Locally delivered antioxidant gel as an adjunct to nonsurgical therapy improves measures of oxidative stress and periodontal disease.
    Chandra RV; Srinivas G; Reddy AA; Reddy BH; Reddy C; Nagarajan S; Naveen A · Journal of periodontal & implant science · 2013
    Randomized trial31 participantsAnti-Inflammatory Support forLycopene
  11. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  12. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  13. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  14. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  15. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle
  16. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  17. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto
  18. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  19. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  20. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto
  21. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  22. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  23. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  24. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  25. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  26. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  27. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  28. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  29. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  30. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  31. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  32. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  33. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  34. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  35. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D
  36. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  37. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  38. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  39. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  40. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc