Product Image

Zinc Magnesium & Vitamin B6

Sierra Fit
4.7
ā˜… ā˜… ā˜… ā˜… ā˜…
(922 ratings)
Zinc 20 mg
Magnesium 300 mg
Product Image
Score81
An economical zinc-magnesium formula with several useful forms and vitamin B6. Oxide content and unclear repeated amounts keep it from being an easy top choice.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Immunity
General Health
Stress Relief
Testosterone Support
Heart Health
Digestive Health
Energy
Fitness

Score 81

An economical zinc-magnesium formula with several useful forms and vitamin B6. Oxide content and unclear repeated amounts keep it from being an easy top choice.
How scoring works
$5.00($0.16 per serving)
iHerb
$ 5.00
Report prices

Analysis

Magnesium citrate and two useful zinc forms give the formula a reasonable absorption base. Magnesium oxide lowers the blend quality, while vitamin B6 supplies a relevant supporting nutrient.

General, immunity, stress, and fitness-related mineral support are the clearest uses. Benefits for focus, mood, skin, or metabolism remain indirect and depend largely on correcting low nutrient intake.

The very low serving cost is attractive, but the supplied data repeats complete values beside multiple mineral sources and appears to reflect sex-specific directions. Users should confirm the intended serving instead of assuming all listed amounts are additive.

Who is it for
  • Value-focused adults seeking zinc and magnesium
  • Active users wanting a basic mineral stack
  • People able to confirm the label serving that applies to them
Best for
  • General mineral support
  • Immunity and stress-related nutrient coverage
  • Budget-conscious daily supplementation

Pros

  • Uses zinc aspartate and L-monomethionine
  • Includes magnesium citrate
  • Very favorable serving value

Cons

  • Contains magnesium oxide
  • Repeated amounts make the total unclear
  • No copper is included alongside zinc

Warnings

  • Confirm the applicable serving directions because the repeated mineral entries may represent different dosing tiers.
  • Magnesium may cause loose stools or abdominal discomfort.
  • Long-term high zinc intake without copper can reduce copper absorption.

Nutrient quality

80 High impact

Useful organic forms are present alongside lower-quality oxide. Substantial magnesium and zinc create tolerance and balance concerns despite a focused design.

Ingredient transparency

80 Highest impact

The core nutrient totals are listed and no proprietary blend hides them. Repeated form entries, missing form proportions, incomplete directions, and absent non-active ingredients reduce clarity.

Customer satisfaction

71 High impact

The supplied average is strong and supported by substantial response volume. No comment-level evidence is available to assess repeated complaints or alignment with the intended use.

Value for money

95 Highest impact

Substantial mineral totals support some practical value. Oxide content and dose-balance concerns weaken quality relative to better-formulated alternatives.

Report analysis

Goals

Immunity
Impact
Highest effect
A+ Goal FitA- Strength of SupportB CoverageA- Formula Quality
Magnesium Ā· 300 mgZinc Ā· 20 mg

Zinc aspartate and zinc L-monomethionine provide direct immune support, while magnesium and vitamin B6 add related metabolic support. The capsule format and organic zinc forms are favorable.

Sex-specific capsule directions make the delivered amounts less straightforward, and magnesium oxide lowers mineral form quality. The combined listed zinc reaches the adult daily upper intake level without copper, which may impair mineral balance during prolonged use.

Study evidence
Magnesium Supportive 8 studies
Zinc Supportive 73 studies
General Health
Impact
Highest effect
A Goal FitB Strength of SupportB- CoverageA- Formula Quality
Magnesium Ā· 300 mgZinc Ā· 20 mg

Magnesium, zinc, and vitamin B6 provide a coherent combination for foundational muscle, nerve, immune, and metabolic functions. The mineral amounts are substantial and use some favorable citrate, aspartate, and monomethionine forms.

Magnesium oxide lowers absorption quality compared with the better forms in the blend. Repeated amount listings across mineral forms also make it unclear whether the label is describing totals or separate contributions.

Study evidence
Magnesium Supportive 114 studies
Zinc Supportive 60 studies
Impact
High effect
A- Goal FitB Strength of SupportC CoverageA- Formula Quality
Magnesium Ā· 300 mgVitamin B6 Ā· 7 mg

Magnesium directly supports relaxation and nervous-system regulation. Magnesium has established relevance, while vitamin B6 provides supportive metabolic context.

The magnesium amount is well aligned for stress support. Citrate is useful, but oxide and undisclosed form proportions lower quality.

Study evidence
Magnesium Supportive 13 studies
Vitamin B6 Supportive 10 studies
Zinc Supportive 9 studies
Testosterone Support
Impact
High effect
B Goal FitB+ Strength of SupportC CoverageA- Formula Quality
Magnesium Ā· 300 mgZinc Ā· 20 mg

Zinc, magnesium, and vitamin B6 form a logical nutritional combination for endocrine support, especially when mineral status is low. The zinc and magnesium amounts are meaningful, although magnesium oxide lowers the absorption quality of the mixed form.

The formula provides depth across two foundational mineral pathways without vitamin D, boron, or a stress adaptogen. Long-term mineral balance would be stronger with copper support, particularly for users taking the higher serving.

Study evidence
Magnesium Disputed 5 studies
Zinc Disputed 7 studies
Impact
High effect
B+ Goal FitB Strength of SupportC CoverageA- Formula Quality
Magnesium Ā· 300 mgVitamin B6 Ā· 7 mg

A substantial magnesium amount supports vascular tone, rhythm-related physiology, and cellular energy. Vitamin B6 and zinc add secondary metabolic and antioxidant support.

Magnesium oxide lowers absorption quality and the citrate-to-oxide proportions are not disclosed. The formula supports one foundational cardiovascular pathway without broader lipid, nitric-oxide, or homocysteine coverage.

Study evidence
Magnesium Supportive 158 studies
Vitamin B6 Supportive 44 studies
Impact
High effect
B+ Goal FitB Strength of SupportC+ CoverageB+ Formula Quality
Zinc Ā· 20 mgMagnesium Ā· 300 mg

Magnesium and zinc address two useful digestive pathways: motility and intestinal-lining maintenance. The amounts are substantial, and citrate plus zinc L-monomethionine improve the otherwise mixed form profile.

Magnesium oxide lowers absorption quality, while the sex-specific directions make the effective amounts less clear than a single serving statement. The combined listed zinc amount reaches the adult upper limit and lacks copper, so long-term daily use deserves caution.

Study evidence
Magnesium Supportive 50 studies
Zinc Supportive 130 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
7 mg
Magnesium (Magnesium Citrate, Magnesium Oxide)
300 mg
Zinc (Zinc Aspartate, Zinc L-Monomethionine)
20 mg
Gluten Free Adults 18–50 Dairy Free No Allergies
Report overview
A Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB+ Value
+4

The combination of zinc aspartate and zinc L-monomethionine provides absorbable forms in a veggie capsule. The listed zinc total reaches the adult upper intake level, while no copper is included to offset long-term competition for absorption. The low serving cost gives good value, but the sex-specific capsule directions make dose interpretation less straightforward.

F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
+6

The magnesium blend combines moderately absorbed citrate with low-absorption oxide, and the proportions are not disclosed. Its elemental amount is clear and well aligned, while vitamin B6 provides useful cofactor support. Very low serving cost improves value, but the oxide component prevents the blend from matching premium forms.

Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS Ā· The New England journal of medicine Ā· 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  2. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; VÔsquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  3. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY Ā· Craniomaxillofacial trauma & reconstruction Ā· 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  4. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J Ā· Biomaterials Ā· 2016
    Randomized trial48 participantsBone Health forMagnesium
  5. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G Ā· Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine Ā· 2022
    Narrative reviewBone Health forMagnesium
  6. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z Ā· Endocrine connections Ā· 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  7. The Effects of the AGE Inhibitor Pyridoxamine on Bone in Older Women With Type 2 Diabetes: A Randomized Clinical Trial.
    Brossfield AV; McMahon DJ; Fernando J; Omeragic B; Majeed R; Agarwal S; Sroga GE; Wang B; Vashishth D; Rubin MR Ā· The Journal of clinical endocrinology and metabolism Ā· 2025
    Randomized trial55 participantsBone Health forVitamin B6
  8. Dietary B vitamin intake and risk of hip fracture: the Singapore Chinese Health Study.
    Dai Z; Wang R; Ang LW; Yuan JM; Koh WP Ā· Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA Ā· 2014
    Cohort study63,257 participantsBone Health forVitamin B6
  9. Hip fracture patients may be vitamin B6 deficient. Controlled study of serum pyridoxal-5'-phosphate.
    Reynolds TM; Marshall PD; Brain AM Ā· Acta orthopaedica Scandinavica Ā· 1993
    Case-control study103 participantsBone Health forVitamin B6
  10. Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls.
    Saito M; Fujii K; Marumo K Ā· Calcified tissue international Ā· 2006
    Case-control study50 participantsBone Health forVitamin B6
  11. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G Ā· Current aging science Ā· 2022
    Narrative review35,298 participants29 studies pooledBone Health forVitamin B6
  12. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    ElmstÄhl S; Gullberg B; Janzon L; Johnell O; ElmstÄhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  13. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD Ā· The Journal of nutrition Ā· 2016
    Randomized trial147 participantsBone Health forZinc
  14. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA Ā· The American journal of clinical nutrition Ā· 2004
    Randomized trial242 participantsBone Health forZinc
  15. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A Ā· Saudi medical journal Ā· 2009
    Randomized trial60 participantsBone Health forZinc
  16. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N Ā· Biological trace element research Ā· 2021
    Meta-analysis40 studies pooledBone Health forZinc
  17. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D Ā· The American journal of clinical nutrition Ā· 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  18. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K Ā· PloS one Ā· 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  19. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M Ā· Journal of cardiovascular pharmacology Ā· 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  20. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H Ā· Current atherosclerosis reports Ā· 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  21. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J Ā· Journal of nephrology Ā· 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  22. Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
    Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW Ā· Therapeutic advances in chronic disease Ā· 2024
    Cohort studyCardiovascular Support forVitamin B6
  23. Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
    MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ Ā· Pediatrics Ā· 2006
    Randomized trial124 participantsCardiovascular Support forVitamin B6
  24. Pyridoxine improves endothelial function in cardiac transplant recipients.
    Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ Ā· The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Ā· 2001
    Randomized trial31 participantsCardiovascular Support forVitamin B6
  25. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ Ā· JAMA Ā· 1998
    Cohort study80,082 participantsCardiovascular Support Heart Health forVitamin B6
  26. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
    MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC Ā· JAMA Ā· 2008
    Randomized trial3,023 participantsCardiovascular Support forVitamin B6
  27. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
    Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D Ā· The Cochrane database of systematic reviews Ā· 2009
    Meta-analysis6,145 participants5 studies pooledCognitive Support forMagnesium
  28. Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
    Zhang C; Sun L; Sun H Ā· Medicine Ā· 2022
    Meta-analysis1,899 participants22 studies pooledCognitive Support forMagnesium
  29. Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
    Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST Ā· East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan Ā· 2026
    Randomized trial40 participantsCognitive Support forMagnesium
  30. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J Ā· Sleep medicine: X Ā· 2025
    Randomized trial80 participantsCognitive Support Energy forMagnesium
  31. Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
    Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM Ā· Minerva anestesiologica Ā· 2021
    Randomized trial80 participantsCognitive Support forMagnesium
  32. Safety and Efficacy of High-Dose Vitamin B6 as an Adjunctive Treatment for Antipsychotic-Induced Hyperprolactinemia in Male Patients With Treatment-Resistant Schizophrenia.
    Zhuo C; Xu Y; Wang H; Fang T; Chen J; Zhou C; Li Q; Liu J; Xu S; Yao C; Yang W; Yang A; Li B; Chen Y; Tian H; Lin C Ā· Frontiers in psychiatry Ā· 2021
    Randomized trial200 participantsCognitive Support forVitamin B6
  33. Associations between dietary B vitamin intakes and cognitive function among elderly individuals: An observational study.
    Chen Q; Huang J; Shi X; Peng Y; Chen A; Huang L; Zhang Y; Chen X Ā· Nutrition (Burbank, Los Angeles County, Calif.) Ā· 2025
    Cross-sectional study2,716 participantsCognitive Support forVitamin B6
  34. Lower Plasma Vitamin B-6 is Associated with 2-Year Cognitive Decline in the Boston Puerto Rican Health Study.
    Palacios N; Scott T; Sahasrabudhe N; Gao X; Tucker KL Ā· The Journal of nutrition Ā· 2020
    Cohort study949 participantsCognitive Support forVitamin B6
  35. Lower water-soluble vitamins and higher homocysteine are associated with neurodegenerative diseases.
    Zhang C; Hu Y; Cao X; Deng Y; Wang Y; Guan M; Wu X; Jiang H Ā· Scientific reports Ā· 2025
    Cohort study926 participantsCognitive Support forVitamin B6
  36. Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction.
    Gordon S; Hoey L; McNulty H; Keenan J; Pangilinan F; Brody LC; Ward M; Strain JJ; McAnena L; McCann A; Molloy AM; Cunningham C; McCarroll K; Hughes CF Ā· BMC medicine Ā· 2025
    Observational study4,553 participantsCognitive Support forVitamin B6
  37. Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
    Janyajirawong R; Vilaichone RK; Sethasine S Ā· Asian Pacific journal of cancer prevention : APJCP Ā· 2021
    Randomized trial69 participantsCognitive Support forZinc
  38. Effects of zinc supplementation on parent and teacher behaviour rating scores in low socioeconomic level Turkish primary school children.
    Uçkardeş Y; Ozmert EN; Unal F; Yurdakök K · Acta paediatrica (Oslo, Norway : 1992) · 2009
    Randomized trial226 participantsCognitive Support forZinc
  39. L-shaped association between dietary zinc intake and cognitive decline in Chinese older people.
    Meng Q; Liu M; Zu C; Su X; Wei Y; Gan X; Zhang Y; He P; Zhou C; Ye Z; Liu C; Qin X Ā· Age and ageing Ā· 2024
    Cohort study3,106 participantsCognitive Support forZinc
  40. The efficacy of zinc augmentation in children with attention deficit hyperactivity disorder under treatment with methylphenidate: A randomized controlled trial.
    Noorazar SG; Malek A; Aghaei SM; Yasamineh N; Kalejahi P Ā· Asian journal of psychiatry Ā· 2021
    Randomized trial60 participantsCognitive Support forZinc
  41. A preliminary report: effects of zinc and micronutrient repletion on growth and neuropsychological function of urban Chinese children.
    Penland JG; Sandstead HH; Alcock NW; Dayal HH; Chen XC; Li JS; Zhao F; Yang JJ Ā· Journal of the American College of Nutrition Ā· 1997
    Randomized trial372 participantsCognitive Support forZinc
  42. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA Ā· World journal of pediatrics : WJP Ā· 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  43. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q Ā· Clinical nutrition (Edinburgh, Scotland) Ā· 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  44. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y Ā· Pediatric gastroenterology, hepatology & nutrition Ā· 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  45. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H Ā· Journal of neurogastroenterology and motility Ā· 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  46. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q Ā· The American journal of clinical nutrition Ā· 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  47. Oral zinc supplementation for the treatment of acute diarrhea in children: a systematic review and meta-analysis.
    Lamberti LM; Walker CL; Chan KY; Jian WY; Black RE Ā· Nutrients Ā· 2014
    Meta-analysis18,822 participants104 studies pooledDigestive Health forZinc
  48. Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial.
    Bhatnagar S; Bahl R; Sharma PK; Kumar GT; Saxena SK; Bhan MK Ā· Journal of pediatric gastroenterology and nutrition Ā· 2004
    Randomized trial287 participantsDigestive Health forZinc
  49. Lower-Dose Zinc for Childhood Diarrhea - A Randomized, Multicenter Trial.
    Dhingra U; Kisenge R; Sudfeld CR; Dhingra P; Somji S; Dutta A; Bakari M; Deb S; Devi P; Liu E; Chauhan A; Kumar J; Semwal OP; Aboud S; Bahl R; Ashorn P; Simon J; Duggan CP; Sazawal S; Manji K Ā· The New England journal of medicine Ā· 2020
    Randomized trial4,500 participantsDigestive Health forZinc
  50. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S Ā· The New England journal of medicine Ā· 1995
    Randomized trial937 participantsDigestive Health General Health forZinc
  51. Short-course prophylactic zinc supplementation for diarrhea morbidity in infants of 6 to 11 months.
    Malik A; Taneja DK; Devasenapathy N; Rajeshwari K Ā· Pediatrics Ā· 2013
    Randomized trial272 participantsDigestive Health forZinc
  52. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E Ā· Journal of cachexia, sarcopenia and muscle Ā· 2024
    Cohort study81,524 participantsEnergy Fitness forMagnesium
  53. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D Ā· Lancet (London, England) Ā· 1991
    Randomized trial32 participantsEnergy forMagnesium
  54. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C Ā· Magnesium research Ā· 2008
    Narrative reviewEnergy forMagnesium
  55. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M Ā· Nutrients Ā· 2018
    Cross-sectional study156,575 participantsFitness forMagnesium
  56. Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A Ā· Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Ā· 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
  57. Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
    Polo-Ferrero L; Recio-Rodriguez JI; GonzÔlez-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-SÔnchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
  58. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M Ā· Journal of the American Medical Directors Association Ā· 2023
    Systematic review45 studies pooledFitness forMagnesium Fitness forZinc
  59. Association between composite dietary antioxidant index and handgrip strength in American adults: Data from National Health and Nutrition Examination Survey (NHANES, 2011-2014).
    Wu D; Wang H; Wang W; Qing C; Zhang W; Gao X; Shi Y; Li Y; Zheng Z Ā· Frontiers in nutrition Ā· 2024
    Cross-sectional study6,019 participantsFitness forZinc
  60. Serum essential elements and muscle health in Chinese adults: a community-based study.
    Ye H; Wang D; Liu S; Yao N; Gui Z; Huang Z; Zeng Y; Liu L; Wan H; Shen J Ā· Nutrition & metabolism Ā· 2025
    Cross-sectional study5,389 participantsFitness forZinc
  61. [Survey of the dietary status and physical activity level and fitness of college freshmen in Chengdu].
    Han H; Lv X; Wang D Ā· Wei sheng yan jiu = Journal of hygiene research Ā· 2010
    Cross-sectional study1,200 participantsFitness forZinc
  62. A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
    Rowland A; Edwards S; Prieto-Bellver G; Menz B; Rowland A; Cornelisse E; Karapetis CS; Wallen MP; Hopkins AM Ā· Journal of the International Society of Sports Nutrition Ā· 2026
    Narrative reviewFitness forZinc
  63. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ Ā· Anesthesiology Ā· 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  64. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S Ā· Lancet (London, England) Ā· 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  65. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY Ā· British journal of anaesthesia Ā· 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  66. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K Ā· American journal of kidney diseases : the official journal of the National Kidney Foundation Ā· 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  67. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH Ā· Reproductive biology and endocrinology : RB&E Ā· 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  68. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY Ā· Nursing open Ā· 2022
    Randomized trial144 participantsGeneral Health forZinc
  69. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group Ā· Archives of ophthalmology (Chicago, Ill. : 1960) Ā· 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  70. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R Ā· Scientific reports Ā· 2026
    Randomized trial84 participantsGeneral Health forZinc
  71. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A Ā· The journal of obstetrics and gynaecology research Ā· 2018
    Randomized trial142 participantsGeneral Health forZinc
  72. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM Ā· The British journal of dermatology Ā· 2003
    Randomized trial200 participantsHair Health forZinc
  73. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N Ā· Journal of cosmetic dermatology Ā· 2018
    Randomized trialHair Health forZinc
  74. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C Ā· The journal of investigative dermatology. Symposium proceedings Ā· 2006
    Randomized trial40 participantsHair Health forZinc
  75. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S Ā· Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) Ā· 2015
    Case-control study216 participantsHair Health forZinc
  76. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS Ā· Annals of dermatology Ā· 2013
    Case-control study342 participantsHair Health forZinc
  77. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M Ā· Frontiers in nutrition Ā· 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  78. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-MorÔn M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  79. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  80. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS Ā· Critical reviews in food science and nutrition Ā· 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forVitamin B6
  81. Intake of folate, vitamin B6 and vitamin B12 and the risk of CHD: the Japan Public Health Center-Based Prospective Study Cohort I.
    Ishihara J; Iso H; Inoue M; Iwasaki M; Okada K; Kita Y; Kokubo Y; Okayama A; Tsugane S; JPHC Study Group Ā· Journal of the American College of Nutrition Ā· 2008
    Cohort study40,803 participantsHeart Health forVitamin B6
  82. The effect of B-vitamins on the prevention and treatment of cardiovascular diseases: a systematic review and meta-analysis.
    Miao Y; Guo Y; Chen Y; Lin Y; Lu Y; Guo Q Ā· Nutrition reviews Ā· 2024
    Meta-analysisHeart Health forVitamin B6
  83. Folate and vitamin B(6) intake and risk of acute myocardial infarction in Italy.
    Tavani A; Pelucchi C; Parpinel M; Negri E; La Vecchia C Ā· European journal of clinical nutrition Ā· 2005
    Case-control study985 participantsHeart Health forVitamin B6
  84. Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis.
    Odler B; Deak AT; Pregartner G; Riedl R; Bozic J; Trummer C; Prenner A; Söllinger L; Krall M; Höflechner L; Hebesberger C; Boxler MS; Berghold A; Schemmer P; Pilz S; Rosenkranz AR · Nutrients · 2021
    Cohort study376 participantsImmunity forMagnesium
  85. Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study.
    Nouri-Majd S; Ebrahimzadeh A; Mousavi SM; Zargarzadeh N; Eslami M; Santos HO; Taghizadeh M; Milajerdi A Ā· Frontiers in nutrition Ā· 2022
    Cross-sectional study250 participantsImmunity forMagnesium
  86. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
    Chaigne-Delalande B; Li FY; O'Connor GM; Lukacs MJ; Jiang P; Zheng L; Shatzer A; Biancalana M; Pittaluga S; Matthews HF; Jancel TJ; Bleesing JJ; Marsh RA; Kuijpers TW; Nichols KE; Lucas CL; Nagpal S; Mehmet H; Su HC; Cohen JI; Uzel G; Lenardo MJ Ā· Science (New York, N.Y.) Ā· 2013
    Single-arm trialImmunity forMagnesium
  87. Effect of magnesium on granulocyte function and on the exercise induced inflammatory response.
    Mooren FC; Golf SW; Völker K · Magnesium research · 2003
    Randomized trialImmunity forMagnesium
  88. Maternal and neonatal outcomes following magnesium sulfate in the setting of chorioamnionitis: a meta-analysis.
    Pergialiotis V; Sapantzoglou I; Rodolaki K; Varthaliti A; Theodora M; Antsaklis P; Thomakos N; Stavros S; Daskalakis G; Papapanagiotou A Ā· Archives of gynecology and obstetrics Ā· 2024
    Meta-analysis6,559 participants8 studies pooledImmunity forMagnesium
  89. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  90. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK Ā· Pediatrics Ā· 1998
    Randomized trial609 participantsImmunity forZinc
  91. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L Ā· Pediatric reports Ā· 2020
    Randomized trial64 participantsImmunity forZinc
  92. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA Ā· Journal of the American Geriatrics Society Ā· 1998
    Randomized trial136 participantsImmunity forZinc
  93. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A Ā· Journal of preventive medicine and hygiene Ā· 2026
    Systematic review13 studies pooledImmunity forZinc
  94. Association of magnesium consumption with type 2 diabetes and glucose metabolism: A systematic review and pooled study with trial sequential analysis.
    Zhao B; Deng H; Li B; Chen L; Zou F; Hu L; Wei Y; Zhang W Ā· Diabetes/metabolism research and reviews Ā· 2021
    Meta-analysis1,168 participants26 studies pooledMetabolism Boost forMagnesium
  95. Magnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysis.
    Tan X; Huang Y Ā· Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Ā· 2022
    Meta-analysis4 studies pooledMetabolism Boost forMagnesium
  96. Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S Ā· Journal of diabetes and metabolic disorders Ā· 2026
    Meta-analysis384 participants5 studies pooledMetabolism Boost forMagnesium
  97. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial.
    Rodríguez-MorÔn M; Guerrero-Romero F · Diabetes care · 2003
    Randomized trial63 participantsMetabolism Boost forMagnesium
  98. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z Ā· Biological trace element research Ā· 2018
    Randomized trial70 participantsMetabolism Boost forMagnesium
  99. Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
    Bor MV; Refsum H; Bisp MR; Bleie Ø; Schneede J; Nordrehaug JE; Ueland PM; Nygard OK; Nexø E · Clinical chemistry · 2003
    Randomized trial90 participantsMetabolism Boost forVitamin B6
  100. Dietary one-carbon metabolism nutrients and risk of MASLD progression: a prospective cohort study.
    Shen L; Wang K; Li R; Li Y; Guo Y; Li F; Yuan J; Yang Z; Xia B; Lin X Ā· European journal of clinical nutrition Ā· 2026
    Cohort study46,800 participantsMetabolism Boost forVitamin B6
  101. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
    Kim H; Enrione EB; Narayanan V; Li T; Campa A Ā· Nutrients Ā· 2022
    Cross-sectional study461 participantsMetabolism Boost forVitamin B6
  102. Influence of oral contraceptives, pyridoxine (vitamin B6), and tryptophan on carbohydrate metabolism.
    Adams PW; Wynn V; Folkard J; Seed M Ā· Lancet (London, England) Ā· 1976
    Clinical trial46 participantsMetabolism Boost forVitamin B6
  103. Effect of oral contraceptives and vitamin B6 deficiency on carbohydrate metabolism.
    Rose DP; Leklem JE; Brown RR; Linkswiler HM Ā· The American journal of clinical nutrition Ā· 1975
    Clinical trialMetabolism Boost forVitamin B6
  104. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
    Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M Ā· Phytotherapy research : PTR Ā· 2021
    Randomized trial84 participantsMetabolism Boost forZinc
  105. Relationship between zinc and glucose metabolism in Japanese adults.
    Suka M; Tsuruta H; Takao T; Yanagisawa H Ā· Diabetology international Ā· 2026
    Cross-sectional study533 participantsMetabolism Boost forZinc
  106. Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review.
    Banaszak M; Górna I; Przysławski J Ā· Nutrients Ā· 2021
    Narrative reviewMetabolism Boost forZinc
  107. Capsaicin and Zinc Signalling Pathways as Promising Targets for Managing Insulin Resistance and Type 2 Diabetes.
    Ferdowsi PV; Ahuja KDK; Beckett JM; Myers S Ā· Molecules (Basel, Switzerland) Ā· 2023
    Narrative reviewMetabolism Boost forZinc
  108. Zinc and Diabetes: A Connection between Micronutrient and Metabolism.
    Ahmad R; Shaju R; Atfi A; Razzaque MS Ā· Cells Ā· 2024
    Narrative reviewMetabolism Boost forZinc
  109. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q Ā· Journal of affective disorders Ā· 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  110. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C Ā· PloS one Ā· 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  111. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S Ā· East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan Ā· 2026
    Randomized trial40 participantsMood Support forMagnesium
  112. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A Ā· Clinical nutrition ESPEN Ā· 2021
    Randomized trial46 participantsMood Support forMagnesium
  113. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D Ā· Journal of affective disorders Ā· 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  114. Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.
    Yosaee S; Clark CCT; Keshtkaran Z; Ashourpour M; Keshani P; Soltani S Ā· General hospital psychiatry Ā· 2022
    Meta-analysisMood Support forZinc
  115. Dietary zinc and iron intake and risk of depression: A meta-analysis.
    Li Z; Li B; Song X; Zhang D Ā· Psychiatry research Ā· 2017
    Meta-analysis9 studies pooledMood Support forZinc
  116. Zinc sulphate: A reasonable choice for depression management in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial.
    Salari S; Khomand P; Arasteh M; Yousefzamani B; Hassanzadeh K Ā· Pharmacological reports : PR Ā· 2016
    Randomized trial43 participantsMood Support forZinc
  117. Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis.
    Cheng YC; Huang WL; Chen WY; Huang YC; Kuo PH; Tu YK Ā· Psychological medicine Ā· 2025
    Meta-analysis17,437 participants192 studies pooledMood Support forZinc
  118. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.
    Sarris J; Ravindran A; Yatham LN; Marx W; Rucklidge JJ; McIntyre RS; Akhondzadeh S; Benedetti F; Caneo C; Cramer H; Cribb L; de Manincor M; Dean O; Deslandes AC; Freeman MP; Gangadhar B; Harvey BH; Kasper S; Lake J; Lopresti A; Lu L; Metri NJ; Mischoulon D; Ng CH; Nishi D; Rahimi R; Seedat S; Sinclair J; Su KP; Zhang ZJ; Berk M Ā· The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry Ā· 2022
    Guideline / consensusMood Support forZinc
  119. Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
    Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC Ā· European journal of nutrition Ā· 2024
    Cohort study5,663 participantsProductivity Boost forMagnesium
  120. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
    Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J Ā· Neuropsychiatric disease and treatment Ā· 2022
    Cohort study327 participantsProductivity Boost forMagnesium
  121. The effects of magnesium L-threonate (MagteinĀ®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ Ā· Frontiers in nutrition Ā· 2026
    Randomized trial100 participantsProductivity Boost forMagnesium
  122. Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
    Lai XN; Sadhwani V; Ng WM; Gani A Ā· Cureus Ā· 2025
    Cohort study667 participantsProductivity Boost forMagnesium
  123. Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
    Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J Ā· Journal of the American Medical Directors Association Ā· 2025
    Cross-sectional study2,768 participantsProductivity Boost forMagnesium
  124. Vitamin B6, B9, and B12 Intakes and Cognitive Performance in Elders: National Health and Nutrition Examination Survey, 2011-2014.
    Xu H; Wang S; Gao F; Li C Ā· Neuropsychiatric disease and treatment Ā· 2022
    Cross-sectional study2,421 participantsProductivity Boost forVitamin B6
  125. Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults.
    Coburn SP; Schaltenbrand WE; Mahuren JD; Clausman RJ; Townsend D Ā· The American journal of clinical nutrition Ā· 1983
    Non-randomized trialProductivity Boost forVitamin B6
  126. Identifying Key Predictors of Cognitive Dysfunction in Older People Using Supervised Machine Learning Techniques: Observational Study.
    Rankin D; Black M; Flanagan B; Hughes CF; Moore A; Hoey L; Wallace J; Gill C; Carlin P; Molloy AM; Cunningham C; McNulty H Ā· JMIR medical informatics Ā· 2024
    Cohort studyProductivity Boost forVitamin B6
  127. Inappropriate nutrients intake is associated with lower functional status and inferior quality of life in older adults with depression.
    Guligowska A; Pigłowska M; Fife E; Kostka J; Sołtysik BK; Kroc Ł; Kostka T Ā· Clinical interventions in aging Ā· 2017
    Case-control study49 participantsProductivity Boost forVitamin B6
  128. A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
    Anlacan VM; Jamora RDG; Krattinger LF; De Longis E; Hartweg M; Steinmann M; Trovò L · Frontiers in nutrition · 2026
    Randomized trial44 participantsProductivity Boost forVitamin B6
  129. Zinc supplementation improved cognitive performance and taste acuity in Indian adolescent girls.
    Tupe RP; Chiplonkar SA Ā· Journal of the American College of Nutrition Ā· 2010
    Randomized trial180 participantsProductivity Boost forZinc
  130. Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Meli AM; Ali A; Mhd Jalil AM; Mohd Yusof H; Tan MMC Ā· Medicina (Kaunas, Lithuania) Ā· 2022
    Meta-analysisProductivity Boost forZinc
  131. Linkages of biomarkers of zinc with cognitive performance and taste acuity in adolescent girls.
    Chiplonkar SA; Kawade R Ā· International journal of food sciences and nutrition Ā· 2015
    Cross-sectional study403 participantsProductivity Boost forZinc
  132. Associations Between Serum Selenium, Zinc, and Copper Levels and Cognitive Function in the Elderly.
    Charernwat P; Chansirikarnjana S; Panpunuan P; Sritara P; Sirivarasai J Ā· Nutrients Ā· 2025
    Cross-sectional study854 participantsProductivity Boost forZinc
  133. Comparative analysis of methyl-donor nutrient intakes and RCPM cognitive performance among school-aged children.
    Apprey C; Asamoah-Boakye O; Annaful VT; Annan RA Ā· Clinical nutrition ESPEN Ā· 2022
    Cross-sectional study2,073 participantsProductivity Boost forZinc
  134. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C Ā· Therapeutics and clinical risk management Ā· 2026
    Randomized trial137 participantsStress Relief forMagnesium
  135. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B Ā· Magnesium research Ā· 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  136. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S Ā· Korean journal of family medicine Ā· 2026
    Randomized trial45 participantsStress Relief forMagnesium
  137. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E Ā· Stress and health : journal of the International Society for the Investigation of Stress Ā· 2021
    Randomized trialStress Relief forMagnesium Stress Relief forVitamin B6
  138. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM Ā· International journal of preventive medicine Ā· 2022
    Randomized trial81 participantsStress Relief forVitamin B6
  139. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM Ā· Shock (Augusta, Ga.) Ā· 2024
    Randomized trial128 participantsStress Relief forVitamin B6
  140. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
    Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C Ā· PloS one Ā· 2019
    Randomized trial264 participantsStress Relief forVitamin B6
  141. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
    Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L Ā· Public health nutrition Ā· 2021
    Cross-sectional study447 participantsStress Relief forVitamin B6
  142. Investigating the effect of zinc supplementation on probability of relapse and mental health in patients with opioid use disorder undergoing methadone maintenance treatment.
    Amini Z; HeidariFarsani E Ā· Substance abuse treatment, prevention, and policy Ā· 2023
    Randomized trial68 participantsStress Relief forZinc
  143. A systematic review of the association between zinc and anxiety.
    Azargoonjahromi A Ā· Nutrition reviews Ā· 2024
    Systematic review9 studies pooledStress Relief forZinc
  144. Zinc acutely and temporarily inhibits adrenal cortisol secretion in humans. A preliminary report.
    Brandão-Neto J; de Mendonça BB; Shuhama T; Marchini JS; Pimenta WP; Tornero MT · Biological trace element research · 1991
    Clinical trial27 participantsStress Relief forZinc
  145. Low Zinc, Copper, and Manganese Intake is Associated with Depression and Anxiety Symptoms in the Japanese Working Population: Findings from the Eating Habit and Well-Being Study.
    Nakamura M; Miura A; Nagahata T; Shibata Y; Okada E; Ojima T Ā· Nutrients Ā· 2019
    Cross-sectional study2,089 participantsStress Relief forZinc
  146. Mediation effects of thyroid hormones in the associations between essential metal elements and anxiety or depression symptoms in the elderly.
    Li J; Wang W; Peng Y; Qin N; Li J; Wei Y; Wang B; Zeng H; Li H; Cheng L Ā· Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine Ā· 2026
    Observational study416 participantsStress Relief forZinc
  147. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L Ā· International journal of andrology Ā· 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  148. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M Ā· Environmental geochemistry and health Ā· 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  149. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH Ā· Health science reports Ā· 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  150. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H Ā· Frontiers in nutrition Ā· 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  151. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R Ā· Biological trace element research Ā· 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  152. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ Ā· Fertility and sterility Ā· 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  153. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC Ā· Clinical therapeutics Ā· 2022
    Scoping reviewTestosterone Support forZinc
  154. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH Ā· Journal of reproduction & infertility Ā· 2020
    Narrative reviewTestosterone Support forZinc
  155. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS Ā· Clinics in endocrinology and metabolism Ā· 1986
    Narrative reviewTestosterone Support forZinc
  156. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS Ā· Special topics in endocrinology and metabolism Ā· 1986
    Narrative reviewTestosterone Support forZinc