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Zinc Picolinate with Vitamin B6

4.8
★ ★ ★ ★ ★
(1953 ratings)
Zinc 30 mg
Rice Protein 250 mg
Product Image
Score81
Clear dosing and zinc dipicolinate are strengths, but 30 mg without copper is better suited to targeted use than indefinite daily maintenance.
How scoring works
Tablet
Quantity:120 Tablet(s) • (120 servings)
Goals:
Immunity
Testosterone Support
General Health
Hair Health
Vision Support

Score 81

Clear dosing and zinc dipicolinate are strengths, but 30 mg without copper is better suited to targeted use than indefinite daily maintenance.
How scoring works
$19.76($0.16 per serving)
iHerb
$ 19.76
Vitacost
$ 26.95
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Analysis

Zinc dipicolinate supplies a focused 30 mg elemental serving, and vitamin B6 adds some nutritional breadth. All listed active amounts are clear, avoiding the dose ambiguity seen in many mineral products.

Thirty milligrams is substantial for routine use and leaves limited room for zinc from other supplements. Copper is absent, while the small brown rice protein addition is unlikely to contribute much beyond the tablet base.

Adults seeking a higher-dose zinc product for a defined period are the clearest fit. Long-term users should consider total zinc intake and whether a lower dose or copper-balanced formula is more appropriate.

Who is it for
  • Adults seeking a clearly dosed zinc supplement
  • People who prefer a picolinate-related zinc form
  • Users planning defined higher-dose use
Best for
  • Focused zinc supplementation
  • Zinc with added vitamin B6
  • Short-to-medium targeted use

Pros

  • Uses zinc dipicolinate
  • Fully discloses all amounts
  • Includes vitamin B6

Cons

  • Zinc amount is high for maintenance
  • No copper is included
  • Brown rice protein adds little practical value

Warnings

  • The 30 mg zinc amount can cause nausea on an empty stomach and should not be stacked with other zinc products.
  • Prolonged use may reduce copper absorption because the formula does not include copper.
  • Zinc can interfere with tetracycline or quinolone antibiotics when taken together, requiring dose separation.

Nutrient quality

82 Highest impact

Well-regarded forms support strong ingredient quality. The core selection remains reasonably aligned with its purpose.

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Ingredient transparency

84 Highest impact

Most active amounts are clearly disclosed. Missing directions and inactive ingredients keep the label information incomplete.

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Customer satisfaction

69 High impact

The supplied average is strong and rests on a substantial review count. No review text was provided to assess recurring complaints or firsthand experiences.

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Value for money

85 Highest impact

Serving efficiency is excellent for the disclosed formula. Some weaker additions reduce value.

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Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A+ Goal FitA+ Strength of SupportB- CoverageA Formula Quality
Zinc · 30 mg

Zinc dipicolinate supplies a well-absorbed 30 mg dose for immune-cell development and signaling. Vitamin B6 adds a related metabolic cofactor, while the capsule remains easy to assess.

The formula is focused and transparent, but the swallowed tablet does not provide zinc lozenge contact for acute use. Long-term daily use may affect copper balance because no copper accompanies the substantial zinc amount.

Study evidence
Zinc Supportive 73 studies
Testosterone Support
Testosterone Support
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA Formula Quality
Zinc · 30 mg

Zinc dipicolinate provides a well-absorbed foundational mineral at a robust amount for correcting low zinc status. Vitamin B6 supports general metabolism but is not a separate major testosterone pathway.

The focused formula offers strong depth in zinc-dependent steroidogenesis rather than broad endocrine coverage. Long-term daily use at this zinc amount may lower copper status because no copper is included.

Study evidence
Zinc Disputed 7 studies
General Health
General Health
Impact
High effect
B+ Goal FitB+ Strength of SupportC CoverageB Formula Quality
Zinc · 30 mg

Zinc dipicolinate provides a well-chosen form of an essential mineral, while vitamin B6 supports related enzyme activity. The disclosed amounts are meaningful and the formula remains reasonably focused.

The zinc amount is above ordinary daily requirements and the small rice-protein addition contributes little. Long-term use can reduce copper absorption, especially when other zinc products are taken at the same time.

Study evidence
Zinc Supportive 60 studies
Hair Health
Hair Health
Impact
High effect
B- Goal FitB+ Strength of SupportF CoverageA- Formula Quality
Zinc · 30 mg

Zinc may support hair recovery when low zinc status contributes to shedding. It does not reliably stimulate extra growth when zinc intake is already adequate.

The 30 mg amount uses zinc dipicolinate, but copper is absent and brown rice protein adds little hair value. Long-term use may still upset mineral balance because no meaningful copper support is provided.

Study evidence
Zinc Supportive 22 studies
Vision Support
Vision Support
Impact
High effect
C+ Goal FitB Strength of SupportD CoverageC+ Formula Quality
Zinc · 30 mg

Zinc picolinate supports retinal mineral functions and vitamin A transport, while vitamin B6 adds little direct ocular value. The product remains much narrower than an AREDS2 or macular carotenoid formula.

The zinc amount and form are clearly disclosed and meaningful. No copper is included, so prolonged use may reduce copper status, while vitamin B6 does not correct that imbalance.

Study evidence
Zinc Supportive 39 studies
Skin Health
Skin Health
Impact
Moderate effect
D Goal FitB Strength of SupportF CoverageC- Formula Quality
Zinc · 30 mg

Zinc dipicolinate provides a well-absorbed mineral involved in normal skin integrity. The amount is substantial and vitamin B6 adds general nutrient metabolism support.

Thirty milligrams of zinc may be high for prolonged routine use, and no copper is included for balance. The small rice-protein amount does not provide meaningful skin structure, while no collagen, hydration active, or targeted antioxidant is present.

Study evidence
Zinc Supportive 66 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 10 mg
Zinc (Zinc Dipicolinate)
 30 mg
whole Brown Rice Protein
250 mg
Gluten Free Adults 18–50 No Allergies Vegetarian
Report overview
Zinc (Zinc Dipicolinate) · 30 mg OverallScore88
A Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

Zinc dipicolinate offers a well-absorbed form at a robust daily amount. The tablet format is less favorable than a rapidly dissolving capsule, and copper is not included to support longer-term mineral balance. The serving cost remains favorable for an effective zinc dose.

View ingredientView products
Loading alternative details
87 Performance

Zinc Picolinate 25 mg

Thompson
<p>Zinc picolinate offers strong absorption potential at a meaningful amount that stays below the usual adult upper limit. The simple formula improves dose clarity, though it omits copper and any non-zinc ingredients supplied by the original.</p>
87 Performance

Zinc Picolinate 22 mg

Solgar
<p>A moderate zinc picolinate amount provides a well-absorbed form without pushing the dose as high as many alternatives. The focused label is easy to assess, but copper and any complementary original ingredients are absent.</p>
86 Performance

Chelated Zinc 30 mg

Carlson
<p>Zinc glycinate chelate supports absorption and tolerance with a clearly stated amount. The single-active design is more transparent than complex blends, though extended daily use without copper may weaken mineral balance.</p>
84 Budget

Zinc Gluconate 30 mg

Swanson
<p>Zinc gluconate provides a clearly disclosed, substantial amount at exceptionally low routine cost. Absorption is reasonable, but sustained daily use without copper may reduce copper status and any non-zinc actives from the original are not replaced.</p>
85 Budget

Zinc Chelate 30 mg

Nature's Way
<p>Zinc bisglycinate offers a well-absorbed form with clear dosing at very low serving cost. The focused capsule omits copper and any supporting ingredients in the original, so prolonged use still requires attention to mineral balance.</p>
86 Budget

L-OptiZinc 30 mg

NOW
<p>Zinc monomethionine provides strong absorption potential with a small amount of chelated copper at economical serving value. The copper addition is too small to fully balance sustained high zinc use, and the focused formula does not replace other original actives.</p>
85 Value

Chelated Zinc 30 mg

Swanson
<p>A branded zinc glycinate chelate combines strong absorption potential with very favorable serving value. The substantial amount and absence of copper make prolonged daily use less suitable without attention to dietary copper.</p>
85 Value

OptiZinc

Source Naturals
<p>Zinc methionine plus a small copper addition offers a useful balance of form quality, disclosure, and serving value. Copper remains modest relative to zinc, and the formula does not preserve any non-zinc actives from the original.</p>
82 Value

Zinc Glycinate

NOW
<p>Zinc bisglycinate provides strong absorption potential at favorable serving value, with pumpkin seed oil as a modest complementary ingredient. Copper is absent, so sustained daily use still needs attention to overall mineral balance.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  2. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  3. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  4. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  5. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  6. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  7. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  8. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  9. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  10. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  11. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  12. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  13. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  14. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  15. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  16. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  17. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  18. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  19. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  20. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  21. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  22. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  23. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  24. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  25. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  26. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  27. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  28. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  29. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  30. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc