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CoQ10 100 mg with PQQ

California Gold Nutrition
4.8
★ ★ ★ ★ ★
(7598 ratings)
Coenzyme Q-10 100 mg
Product Image
Score86
CoQ10 100 mg with PQQ provides 100 mg of ubiquinone with strong serving value. The formula remains focused on mitochondrial support and does not cover broader cardiovascular nutrient pathways.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Anti-Aging
Heart Health
Cardiovascular Support
Energy
Metabolism Boost
Anti-Inflammatory Support

Score 86

CoQ10 100 mg with PQQ provides 100 mg of ubiquinone with strong serving value. The formula remains focused on mitochondrial support and does not cover broader cardiovascular nutrient pathways.
How scoring works
$18.22($0.30 per serving)
iHerb
$ 18.22
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Analysis

A clearly identified maintenance amount of ubiquinone is paired with 10 mg of PQQ in an absorption-friendly format. The serving provides 100 mg of ubiquinone in a softgel.

CoQ10 supports cellular energy production and antioxidant defenses. Ubiquinone is a clearly identified and widely used maintenance form of CoQ10. Softgel delivery is compatible with routine use of a fat-soluble ingredient, although carrier details still matter, while PQQ at 10 mg adds a complementary mitochondrial cofactor.

The formula remains focused on mitochondrial support and does not cover broader cardiovascular nutrient pathways. The 60-serving supply offers strong serving value, so form, delivery, and intended dose should guide the choice.

Who is it for
  • Adults seeking 100 mg of CoQ10
  • People who prefer a softgel format
  • Users who want CoQ10 paired with PQQ
Best for
  • Cellular energy support
  • Antioxidant support
  • Routine CoQ10 supplementation

Pros

  • 100 mg CoQ10 amount is fully disclosed
  • Ubiquinone identifies the active form
  • Includes 10 mg of PQQ as a complementary cofactor
  • 60 servings per container
  • Strong serving value

Cons

  • The formula remains focused on mitochondrial support and does not cover broader cardiovascular nutrient pathways.
  • Complete carrier and excipient details are limited.
  • The focused formula provides limited coverage beyond mitochondrial and antioxidant support.

Warnings

  • CoQ10 may reduce the effect of warfarin, so anticoagulation should be monitored by the prescriber when use starts, stops, or changes.
  • The carrier oil is not fully identified, so people with oil or excipient sensitivities should check the complete label before use.
  • Count the 10 mg PQQ when combining this with another mitochondrial-support formula.

Nutrient quality

94 Highest impact

Ubiquinone and PQQ are clear, and the softgel format supports absorption of fat-soluble CoQ10. The 100 mg amount is meaningful for routine CoQ10 use.

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Ingredient transparency

83 Highest impact

Active ingredients have stated amounts and no proprietary blend hides a dose. Serving count is supplied, while full directions and the other-ingredients list are missing.

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Customer satisfaction

72 High impact

The supplied aggregate rating is the only evidence of general satisfaction and its reliability depends on rating volume. No comment-level evidence is available to assess recurring complaints or confirm how experience matches the intended purpose.

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Value for money

92 Highest impact

The effective amount and favorable serving cost strongly support formula value. The product compares very well with similar CoQ10 options.

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Goals

Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitA Strength of SupportB+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 at 100 mg directly supports mitochondrial energy production and antioxidant defense, both relevant to biological aging. PQQ at 10 mg adds a complementary mitochondrial redox signal, and the softgel supports CoQ10 absorption.

The formula adds PQQ as a complementary mitochondrial redox pathway but does not cover structural aging or glycation. CoQ10 may reduce the anticoagulant effect of warfarin, so users of that medicine need prescriber guidance.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Heart Health
Heart Health
Impact
Highest effect
A Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports heart-muscle energy production, while PQQ adds a complementary mitochondrial antioxidant pathway. The softgel improves delivery of fat-soluble ubiquinone and both amounts are clearly disclosed.

The 100 mg CoQ10 serving fits maintenance use rather than high-potency support. PQQ's cardiovascular evidence is less developed than CoQ10 evidence, so it remains a secondary feature.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A- Goal FitB+ Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy production in heart muscle, while PQQ adds a related mitochondrial and antioxidant mechanism. The combination remains focused and does not address lipids, vasodilation, rhythm minerals, or homocysteine.

The CoQ10 and PQQ amounts are clear and meaningful, although ubiquinone is less absorption oriented than ubiquinol. PQQ has less direct cardiovascular evidence than CoQ10, so it should be viewed as a secondary addition.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Energy
Energy
Impact
Highest effect
A- Goal FitB Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 directly supports mitochondrial energy production, and PQQ adds a complementary cellular-energy component. The 100 mg CoQ10 amount is practical for maintenance, though effects can vary with baseline need.

The softgel format is a meaningful advantage for fat-soluble CoQ10 compared with a dry capsule. Both active amounts are clear, and the formula stays focused without unrelated additions.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 provides focused support for mitochondrial energy production at a useful maintenance amount. PQQ adds a complementary redox-signaling role without turning the formula into a broad metabolic blend.

Softgel delivery suits this fat-soluble active, although ubiquinone still requires conversion to ubiquinol. The combination remains narrow and does not address thermogenesis, glycemic control, or thyroid support.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B Goal FitB+ Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 provides relevant antioxidant and mitochondrial support that may help moderate systemic inflammatory signaling. The maintenance-level amount has useful human evidence, while PQQ adds complementary oxidative-stress support with less direct inflammation evidence.

Softgel delivery suits fat-soluble ubiquinone, and both active amounts are clearly stated. The focused formula has good depth but does not directly cover major botanical or immune-regulating pathways.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Coenzyme Q-10 (Ubiquinone)
 100 mg
Pyrroloquinoline Quinone Disodium Salt
10 mg
Gluten Free Adults 18–50 Dairy Free No Allergies
Report overview
Coenzyme Q-10 (Ubiquinone) · 100 mg OverallScore80
B Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA- Value

Ubiquinone comes in a softgel that supports absorption of this fat-soluble compound. The maintenance-level amount is clearly stated, and PQQ adds a complementary formulation feature. Its below-median serving cost provides good value.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
<p>Ingredient quality is better supported by 200 mg ubiquinol, the reduced CoQ10 form, keeping the alternative closely aligned with the CoQ10 collection. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.</p>
87 Performance

Mega CoQ10 Ubiquinol 100 mg

Qunol
<p>Ingredient quality is better supported by 100 mg ubiquinol, the reduced CoQ10 form, keeping the alternative closely aligned with the CoQ10 collection. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.</p>
87 Performance

QH-absorb 100 mg

Jarrow Formulas
<p>Ingredient quality is better supported by 100 mg ubiquinol, the reduced CoQ10 form, keeping the alternative closely aligned with the CoQ10 collection. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.</p>
84 Budget

CoQ10 100 mg

Best Naturals
<p>100 mg ubiquinone retains the core ingredient at a lower serving cost. The focused label keeps the comparison close to the original while making the CoQ10 form straightforward to assess.</p>
85 Budget

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best
<p>100 mg ubiquinone retains the core ingredient at a lower serving cost. Black-pepper extract adds an absorption-oriented companion ingredient, though medicine interactions may need consideration.</p>
84 Budget

CoQ10 100 mg

California Gold Nutrition
<p>100 mg ubiquinone retains the core ingredient at a lower serving cost. The focused label keeps the comparison close to the original while making the CoQ10 form straightforward to assess.</p>
86 Value

Ubiquinol 100 mg

NOW
<p>100 mg ubiquinol, the reduced CoQ10 form combines a relevant CoQ10 serving with favorable value evidence. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.</p>
85 Value

Mega Ubiquinol CoQ10 100 mg

Qunol
<p>100 mg ubiquinol, the reduced CoQ10 form combines a relevant CoQ10 serving with favorable value evidence. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.</p>
87 Value

QH-absorb 100 mg

Jarrow Formulas
<p>100 mg ubiquinol, the reduced CoQ10 form combines a relevant CoQ10 serving with favorable value evidence. Naming the reduced CoQ10 form gives clearer form information than the original's ubiquinone or unspecified CoQ10.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  3. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  4. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  5. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  6. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  7. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  8. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  9. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  10. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  11. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  12. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  13. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  14. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  15. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  16. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  17. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  18. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  19. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  20. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  21. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  22. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  23. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  24. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  25. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  26. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  27. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  28. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  29. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  30. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  31. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10