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Ultra Strength Sleep

OLLY
4.2
★ ★ ★ ★ ★
(9219 ratings)
Theanine 100 mg
Melatonin 10 mg
Product Image
Score63
A broad sleep softgel is held back by very high melatonin, weaker magnesium oxide, and token herbal doses.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
Sleep Support
Stress Relief

Score 63

A broad sleep softgel is held back by very high melatonin, weaker magnesium oxide, and token herbal doses.
How scoring works
$18.99($0.63 per serving)
iHerb
$ 19.99
Amazon
$ 18.99
Walmart
$ 18.99
Vitacost
$ 21.29
Report prices

Analysis

The softgel combines theanine with magnesium and three named bedtime botanicals. Its fat-containing format may be easy to swallow, though it is not central to the water-soluble actives.

Melatonin is very high and raises a substantial risk of next-day grogginess. Magnesium oxide is less well absorbed and more likely to affect the digestive tract, while the botanical amounts are small.

The product is best limited to adults who already know they tolerate high-dose melatonin. Lower-dose formulas offer a safer starting point and often provide similar practical sleep-onset support.

Who is it for
  • Adults already tolerant of very high melatonin
  • People who prefer softgels
Best for
  • Strong sleep-onset support
  • Combined theanine and magnesium

Pros

  • Useful theanine amount
  • All botanicals are named
  • Includes magnesium

Cons

  • Melatonin amount is very high
  • Uses magnesium oxide
  • Botanical extracts are small

Warnings

  • High melatonin may cause marked next-day drowsiness; avoid driving until fully alert
  • Magnesium oxide may cause loose stools or stomach discomfort
  • Chamomile may trigger reactions in people sensitive to ragweed-family plants

Nutrient quality

56 Moderate impact

The broad formula covers sleep timing, mental relaxation, and mineral support. Excessive melatonin, poorly absorbed magnesium oxide, and tiny botanical amounts substantially weaken quality.

Ingredient transparency

82 Highest impact

Every listed active amount is disclosed, and no proprietary blend obscures the formula. Complete daily directions and inactive-ingredient details are not available.

Customer satisfaction

68 High impact

The aggregate satisfaction measure is favorable, with response volume determining how much confidence it deserves. Comment-level evidence is absent, so recurring complaints and purpose fit cannot be verified.

Value for money

43 Lower impact

Broad ingredient coverage does not justify the premium well because dosing and forms are weak. High melatonin and token botanicals reduce quality-adjusted competitiveness.

Report analysis

Goals

Sleep Support
Sleep Support
Impact
High effect
A Goal FitC Strength of SupportB+ CoverageB- Formula Quality
Magnesium · 150 mgMelatonin · 10 mgTheanine · 100 mg

The broad sleep blend covers circadian timing, mental relaxation, and mineral support. Melatonin, L-theanine, and magnesium are relevant, but the very high melatonin amount and magnesium oxide form weaken practical dose quality.

All active amounts are disclosed, yet several herbs appear in small quantities and the formula lacks sustained release. The high melatonin amount may increase vivid dreams or next-day drowsiness, especially in sensitive users.

Study evidence
Magnesium Supportive 23 studies
Melatonin Supportive 181 studies
Theanine Supportive 8 studies
Stress Relief
Stress Relief
Impact
High effect
B Goal FitD+ Strength of SupportC+ CoverageC Formula Quality
Magnesium · 150 mgTheanine · 100 mg

The softgel covers several nighttime calming pathways but is designed more for sedation than stress resilience. It provides 10 mg of melatonin, 100 mg of L-theanine, magnesium oxide, and small herb extracts for the stated purpose.

The melatonin amount is very high, magnesium uses oxide, and the herb amounts are small. The 10 mg melatonin amount may cause substantial next-day drowsiness or vivid dreams.

Study evidence
Magnesium Supportive 13 studies
Melatonin Supportive 21 studies
Theanine Supportive 16 studies
Brain Health
Brain Health
Impact
Moderate effect
D+ Goal FitC+ Strength of SupportC CoverageB- Formula Quality
Magnesium · 150 mg

Theanine and magnesium offer indirect support for calm attention, while sleep may influence next-day cognition. The formula remains centered on sedation and sleep onset rather than memory or neuroprotection.

Theanine is usefully dosed, but magnesium oxide has weak absorption and the herbs are modest. The high melatonin amount may increase next-day grogginess and reduce alert cognitive performance.

Study evidence
Magnesium Supportive 86 studies
Melatonin Supportive 29 studies
Theanine Supportive 17 studies
Productivity Boost
Productivity Boost
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC CoverageB Formula Quality
Magnesium · 150 mgTheanine · 100 mg

Melatonin, L-theanine, and calming botanicals provide substantial sleep support that may indirectly improve next-day performance. The formula is sedating and does not support daytime focus directly.

Magnesium oxide is poorly absorbed, while 10 mg melatonin is a high amount for routine sleep support. Such a dose may cause next-day drowsiness, vivid dreams, or impaired morning alertness.

Study evidence
Magnesium Supportive 10 studies
Theanine Supportive 5 studies
Mood Support
Mood Support
Impact
Moderate effect
D+ Goal FitC- Strength of SupportC- CoverageC Formula Quality
Magnesium · 150 mg

Theanine, magnesium, and calming herbs support relaxation, but the design is dominated by a strong melatonin sleep signal. It is not well aligned with broad daytime mood support.

Magnesium oxide is a less absorbable form, and the botanical amounts are small. The 10 mg melatonin amount has a notable risk of next-day grogginess, vivid dreams, and impaired alertness.

Study evidence
Magnesium Supportive 60 studies
Theanine Supportive 12 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Fat
0.5 Gram(s)
Magnesium (Magnesium Oxide)
 150 mg
Melatonin
10 mg
L-Theanine
100 mg
Chamomile flower extract
17 mg
Passionflower Flower Extract
17 mg
Lemon Balm aerial parts extract
16 mg
Gluten Free Adults 18–50
Report overview
Theanine · 100 mg OverallScore76
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Generic L-theanine reaches an effective amount with clear label disclosure. The source has no branded purity standard, and the sleep-focused blend is not a simple theanine supplement. Cost efficiency is weak for theanine alone, while the 10 mg melatonin amount may increase next-day grogginess or vivid dreams.

View ingredientView products
Melatonin · 10 mg OverallScore45
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD Value
The single softgel provides a clearly labeled dose, but 10 mg is substantially above the preferred physiological range. The formula lacks sustained release and independent purity verification despite including several calming compounds. The high dose may increase next-day drowsiness, and the premium serving cost weakens value.
View ingredientView products
Loading alternative details
92 Performance

Tranquil Sleep

Natural Factors Stress-Relax
<p>Branded 200 mg Suntheanine, 3 mg melatonin, and 30 mg fully disclosed 5-HTP provide broad relaxation and sleep-onset support without an opaque blend. The 5-HTP can interact with serotonin-raising medicines, so that added depth is not appropriate for everyone.</p>
89 Performance

L-Theanine 200 mg Double Strength

Swanson
<p>A substantial 200 mg branded Suntheanine dose provides stronger, clearly identified relaxation support without melatonin. It may suit users who want to avoid next-day effects from melatonin, but it offers less direct support for sleep timing than the original.</p>
90 Performance

Melatonin 1.0 mg Orange Flavor

Source Naturals Sleep Science
<p>The focused 1 mg melatonin lozenge uses a conservative amount and avoids lightly dosed or undisclosed extras. It gives up the original formula’s theanine support, making it more suitable for sleep timing than broader bedtime relaxation.</p>
86 Budget

Fast-Dissolve Melatonin 3 mg Artificial Strawberry Flavor

Spring Valley
<p>The very low serving cost retains a clearly disclosed 3 mg melatonin dose in a fast-dissolve format. It omits L-theanine and the original formula’s other calming ingredients, so the savings come with narrower support.</p>
88 Budget

Melatonin 1 mg Fast Dissolve Strawberry Natural Flavor

Natrol
<p>The low-cost fast-dissolve tablet uses a conservative 1 mg melatonin amount for sleep timing. It is simpler than the original and leaves out L-theanine, making it a better fit when minimizing both cost and ingredient count matters.</p>
87 Budget

Melatonin Lozenges 3 mg

Life Extension
<p>A low serving cost provides 3 mg melatonin in a focused lozenge with no hidden blend. The streamlined formula is easier to assess than the original, though it does not provide L-theanine for relaxation support.</p>
94 Value

Sleep Regimen 3-in-1

NOW
<p>A low serving cost combines 3 mg melatonin, 200 mg L-theanine, and 50 mg Griffonia-derived 5-HTP with all amounts disclosed. The formula provides more bedtime depth for the money, but 5-HTP can interact with serotonin-raising medicines.</p>
89 Value

L-Theanine 100 mg

California Gold Nutrition
<p>Branded AlphaWave L-theanine supplies a clear 100 mg amount at a low serving cost. It offers clean relaxation support without melatonin, though users seeking direct sleep-timing support would need a different approach.</p>
88 Value

Melatonin Lozenge 2.5 mg

Nature's Way
<p>A practical 2.5 mg melatonin lozenge provides straightforward sleep-onset support at a very low serving cost. It lacks L-theanine and other calming actives, but the focused label offers clearer value than paying for lightly dosed extras.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  4. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  5. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  6. Current Evidence on Common Dietary Supplements for Sleep Quality.
    Esquivel MK; Ghosn B · American journal of lifestyle medicine · 2025
    Narrative reviewSleep Support forTheanine
  7. Antenatal magnesium sulfate and neuroprotection.
    Doyle LW · Current opinion in pediatrics · 2012
    Meta-analysis6,145 participants5 studies pooledBrain Health forMagnesium
  8. No. 376-Magnesium Sulphate for Fetal Neuroprotection.
    Magee LA; De Silva DA; Sawchuck D; Synnes A; von Dadelszen P · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020
    Guideline / consensus4,446 participantsBrain Health forMagnesium
  9. Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review.
    Shepherd ES; Goldsmith S; Doyle LW; Middleton P; Marret S; Rouse DJ; Pryde P; Wolf HT; Crowther CA · Obstetrics and gynecology · 2024
    Systematic review5,917 participants6 studies pooledBrain Health forMagnesium
  10. Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis.
    Wolf HT; Huusom LD; Henriksen TB; Hegaard HK; Brok J; Pinborg A · BJOG : an international journal of obstetrics and gynaecology · 2020
    Meta-analysis5,917 participants6 studies pooledBrain Health forMagnesium
  11. Magnesium sulfate and fetal neuroprotection: overview of clinical evidence.
    Chollat C; Marret S · Neural regeneration research · 2020
    Narrative reviewBrain Health forMagnesium
  12. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  13. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  14. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  15. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  16. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  17. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Sleep Support forTheanine
  18. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  19. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health forTheanine
  20. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health forTheanine
  21. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Productivity Boost forTheanine
  22. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  23. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  24. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  25. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  26. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  27. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  28. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsMood Support Stress Relief forTheanine
  29. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  30. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine
  31. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  32. Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
    Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC · European journal of nutrition · 2024
    Cohort study5,663 participantsProductivity Boost forMagnesium
  33. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
    Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J · Neuropsychiatric disease and treatment · 2022
    Cohort study327 participantsProductivity Boost forMagnesium
  34. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsProductivity Boost forMagnesium
  35. Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
    Lai XN; Sadhwani V; Ng WM; Gani A · Cureus · 2025
    Cohort study667 participantsProductivity Boost forMagnesium
  36. Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
    Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J · Journal of the American Medical Directors Association · 2025
    Cross-sectional study2,768 participantsProductivity Boost forMagnesium
  37. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledProductivity Boost forTheanine
  38. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsProductivity Boost Stress Relief forTheanine
  39. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  40. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsProductivity Boost forTheanine
  41. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  42. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  43. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  44. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  45. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  46. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  47. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  48. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  49. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  50. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  51. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  52. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsSleep Support forTheanine
  53. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  54. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  55. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  56. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  57. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
    Rahafard S; Akbari Jokar Z; Hosseini SA; Alaee E · Annals of medicine and surgery (2012) · 2024
    Randomized trial202 participantsStress Relief forMelatonin
  58. Comparison of Effects of Melatonin and Gabapentin on Post Operative Anxiety and Pain in Lumbar Spine Surgery: A Randomized Clinical Trial.
    Javaherforooshzadeh F; Amirpour I; Janatmakan F; Soltanzadeh M · Anesthesiology and pain medicine · 2022
    Randomized trial90 participantsStress Relief forMelatonin
  59. Melatonin for pre- and postoperative anxiety in adults.
    Hansen MV; Halladin NL; Rosenberg J; Gögenur I; Møller AM · The Cochrane database of systematic reviews · 2015
    Meta-analysis774 participants12 studies pooledStress Relief forMelatonin
  60. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
    Demirhan Kayacik A; İlcioglu K · Archives of women's mental health · 2024
    Meta-analysis441 participants5 studies pooledStress Relief forMelatonin
  61. Premedication effect of melatonin on propofol induction dose for anesthesia, anxiety, orientation and sedation after abdominal surgery: a double-blinded randomized trial.
    Norouzi A; Fateh S; Modir H; Kamali A; Akrami L · Medical gas research · 2020
    Randomized trial88 participantsStress Relief forMelatonin
  62. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine