Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
Randomized trial236 participantsflagEnergy forscienceCoenzyme Q-10
- Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
Meta-analysis24 studies pooledflagEnergy forscienceCoenzyme Q-10
- Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
Cross-sectional study25 participantsflagEnergy forscienceCoenzyme Q-10
- Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
Meta-analysis575 participants12 studies pooledflagEnergy forscienceCoenzyme Q-10
- Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
Systematic review16 studies pooledflagEnergy forscienceCoenzyme Q-10
- Can coenzyme q10 improve clinical and molecular parameters in fibromyalgia?
Cordero MD; Alcocer-Gómez E; de Miguel M; Culic O; Carrión AM; Alvarez-Suarez JM; Bullón P; Battino M; Fernández-RodrÃguez A; Sánchez-Alcazar JA · Antioxidants & redox signaling · 2014
Randomized trial20 participantsflagEnergy forscienceCoenzyme Q-10
- Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
Systematic review16 studies pooledflagEnergy forscienceCoenzyme Q-10
- Coenzyme Q10 supplementation in rheumatic diseases: A systematic review.
Freire de Carvalho J; Skare T · Clinical nutrition ESPEN · 2024
Systematic review483 participants20 studies pooledflagEnergy forscienceCoenzyme Q-10
- Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome.
Fukuda S; Nojima J; Kajimoto O; Yamaguti K; Nakatomi Y; Kuratsune H; Watanabe Y · BioFactors (Oxford, England) · 2017
Randomized trial63 participantsflagEnergy forscienceCoenzyme Q-10
- Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals.
Mizuno K; Sasaki AT; Watanabe K; Watanabe Y · Nutrients · 2021
Clinical trial62 participantsflagEnergy forscienceCoenzyme Q-10
- Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
Narrative reviewflagAnti-Aging forscienceCoenzyme Q-10
- Coenzyme Q10 Supplementation in Aging and Disease.
Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
Narrative reviewflagAnti-Aging forscienceCoenzyme Q-10
- Coenzyme Q10, a cutaneous antioxidant and energizer.
Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
Clinical trialflagAnti-Aging forscienceCoenzyme Q-10
- Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
Cross-sectional study4,260 participantsflagAnti-Aging forscienceCoenzyme Q-10
- Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
Randomized trial40 participantsflagAnti-Aging forscienceCoenzyme Q-10
- Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
Cohort study1,550 participantsflagAnti-Aging forscienceVitamin E
- Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
Cohort study960 participantsflagAnti-Aging forscienceVitamin E
- Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study.
Corina A; Rangel-Zúñiga OA; Jiménez-Lucena R; Alcalá-DÃaz JF; Quintana-Navarro G; Yubero-Serrano EM; López-Moreno J; Delgado-Lista J; Tinahones F; Ordovás JM; López-Miranda J; Pérez-MartÃnez P · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
Observational study1,002 participantsflagAnti-Aging forscienceVitamin E
- The L-shaped link between total antioxidant capacity and phenotypic age acceleration: evidence from NHANES 2003-2010.
Wu Y; Xiang M; Zhao Y; Zhang Y; Cheng W; Deng J · Biogerontology · 2025
Cross-sectional study16,395 participantsflagAnti-Aging forscienceVitamin E
- Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M · Experimental gerontology · 2014
Cohort study140 participantsflagAnti-Aging forscienceVitamin E
- The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
Randomized trial43 participantsflagAnti-Inflammatory Support forscienceCoenzyme Q-10
- The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
Randomized trial55 participantsflagAnti-Inflammatory Support forscienceCoenzyme Q-10
- Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
Meta-analysis1,517 participants31 studies pooledflagAnti-Inflammatory Support forscienceCoenzyme Q-10
- Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
Meta-analysis509 participants9 studies pooledflagAnti-Inflammatory Support forscienceCoenzyme Q-10
- Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
Randomized trial58 participantsflagAnti-Inflammatory Support forscienceCoenzyme Q-10
- Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
Randomized trial110 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
Meta-analysis495 participants12 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
Meta-analysis46 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
Meta-analysis8 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
Randomized trial71 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
Meta-analysis2,794 participants50 studies pooledflagCardiovascular Support flagHeart Health forscienceCoenzyme Q-10
- Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
Randomized trial60 participantsflagCardiovascular Support forscienceCoenzyme Q-10
- The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
Randomized trial420 participantsflagCardiovascular Support forscienceCoenzyme Q-10
- [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
Meta-analysis1,139 participants6 studies pooledflagCardiovascular Support forscienceCoenzyme Q-10
- Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
Randomized trialflagCardiovascular Support forscienceCoenzyme Q-10
- Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
Meta-analysis16 studies pooledflagCardiovascular Support forscienceVitamin E
- Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
Randomized trial90 participantsflagCardiovascular Support forscienceVitamin E
- Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
Randomized trial9,541 participantsflagCardiovascular Support forscienceVitamin E
- Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
Cohort study34,955 participantsflagCardiovascular Support forscienceVitamin E
- Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
Randomized trial62 participantsflagCardiovascular Support forscienceVitamin E
- Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
Meta-analysis1,126 participants13 studies pooledflagEnergy forscienceCoenzyme Q-10
- Antifatigue effects of coenzyme Q10 during physical fatigue.
Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
Randomized trial17 participantsflagEnergy forscienceCoenzyme Q-10
- Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
Randomized trial51 participantsflagHeart Health forscienceCoenzyme Q-10
- Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
Meta-analysis1,831 participants26 studies pooledflagHeart Health forscienceCoenzyme Q-10
- Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
Meta-analysis3,422 participants64 studies pooledflagHeart Health flagMetabolism Boost forscienceCoenzyme Q-10
- Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
Randomized trial101 participantsflagHeart Health forscienceCoenzyme Q-10
- Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
Randomized trial101 participantsflagMetabolism Boost forscienceCoenzyme Q-10
- Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
Meta-analysis2,362 participants41 studies pooledflagMetabolism Boost forscienceCoenzyme Q-10
- Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
Randomized trial100 participantsflagMetabolism Boost forscienceCoenzyme Q-10
- The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
Randomized trial40 participantsflagMetabolism Boost forscienceCoenzyme Q-10