Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Safety and stress-reducing effects of rosemary extract: an open-label trial and randomized double-blind crossover study.
Kuwata H; Ookoshi K; Shimazu K; Fukumitsu S; Aida K · Journal of clinical biochemistry and nutrition · 2025
Randomized trial40 participantsflagStress Relief forscienceRosemary
- Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial.
Araki R; Sasaki K; Onda H; Nakamura S; Kassai M; Kaneko T; Isoda H; Hashimoto K · Nutrients · 2021
Randomized trial21 participantsflagStress Relief forscienceRosemary
- The Effect of Inhalation Aromatherapy and Music Therapy on Anxiety in Patients Undergoing Shockwave Lithotripsy: A Randomized Controlled Clinical Trial.
Rohi Ganji M; Jafari F; Rezaeian S; Abdi H; Farzaei MH; Khatony A · Evidence-based complementary and alternative medicine : eCAM · 2022
Randomized trial176 participantsflagStress Relief forscienceRosemary
- Short-term study on the effects of rosemary on cognitive function in an elderly population.
Pengelly A; Snow J; Mills SY; Scholey A; Wesnes K; Butler LR · Journal of medicinal food · 2012
Randomized trial28 participantsflagCognitive Support forscienceRosemary
- Acute ingestion of rosemary water: Evidence of cognitive and cerebrovascular effects in healthy adults.
Moss M; Smith E; Milner M; McCready J · Journal of psychopharmacology (Oxford, England) · 2019
Randomized trial80 participantsflagCognitive Support forscienceRosemary
- The effect of rosemary hydroalcoholic extract on cognitive function and activities of daily living of patients with chronic obstructive pulmonary disease (COPD): A clinical trial.
Momeni Safarabadi A; Gholami M; Kordestani-Moghadam P; Ghaderi R; Birjandi M · Explore (New York, N.Y.) · 2024
Randomized trial77 participantsflagCognitive Support forscienceRosemary
- Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis.
Tiemtad P; Ingkaninan K; Temkitthawon P; Thimkorn P; Rattanachaisit N; Teaktong T; Dhippayom T · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
Meta-analysis2,107 participants29 studies pooledflagBrain Health flagCognitive Support flagMental Focus forscienceBacopa
- The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects.
Nathan PJ; Clarke J; Lloyd J; Hutchison CW; Downey L; Stough C · Human psychopharmacology · 2019
Randomized trial38 participantsflagBrain Health flagCognitive Support forscienceBacopa
- Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
Kongkeaw C; Dilokthornsakul P; Thanarangsarit P; Limpeanchob N; Norman Scholfield C · Journal of ethnopharmacology · 2014
Meta-analysis518 participants9 studies pooledflagBrain Health flagMental Focus flagProductivity Boost forscienceBacopa
- The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
Pase MP; Kean J; Sarris J; Neale C; Scholey AB; Stough C · Journal of alternative and complementary medicine (New York, N.Y.) · 2012
Systematic review6 studies pooledflagCognitive Support flagProductivity Boost forscienceBacopa
- Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
Randomized trial30 participantsflagMental Focus flagProductivity Boost flagStress Relief forscienceTheanine
- Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
Randomized trial48 participantsflagProductivity Boost flagMental Focus forscienceTheanine
- Promising, but Not Completely Conclusive-The Effect of l-Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
Mátyus RO; Szikora Z; Bodó D; Vargáné Szabó B; Csupor É; Csupor D; Tóth B · Journal of clinical medicine · 2025
Meta-analysis148 participants5 studies pooledflagMental Focus forscienceTheanine
- Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
Meta-analysis1,168 participants31 studies pooledflagProductivity Boost forscienceTheanine
- Comparative efficacy of Medhya Rasayana,Bacopa monnieri, and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: A prakriti-based double-blind, randomized controlled trial.
Verma J; Rathi R; Anamika; Rathi B; Pandey VB · Journal of Ayurveda and integrative medicine · 2025
Randomized trial180 participantsflagBrain Health flagCognitive Support forscienceBacopa
- Plant-derived nootropics and human cognition: A systematic review.
Lorca C; Mulet M; Arévalo-Caro C; Sanchez MÁ; Perez A; Perrino M; Bach-Faig A; Aguilar-Martínez A; Vilella E; Gallart-Palau X; Serra A · Critical reviews in food science and nutrition · 2023
Systematic review256 studies pooledflagBrain Health forscienceBacopa
- The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
Feng X; Fan S; Wei F · Frontiers in pharmacology · 2026
Meta-analysis1,861 participants25 studies pooledflagBrain Health flagCognitive Support forscienceBacopa
- Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
Randomized trial30 participantsflagBrain Health flagCognitive Support forscienceTheanine
- A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
Randomized trialflagBrain Health flagStress Relief forscienceTheanine
- Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
Meta-analysis50 studies pooledflagBrain Health flagCognitive Support flagMental Focus forscienceTheanine
- Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
Randomized trial27 participantsflagBrain Health flagCognitive Support forscienceTheanine
- Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
Randomized trialflagBrain Health flagMental Focus flagProductivity Boost forscienceTheanine
- A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations.
Kean JD; Downey LA; Stough C · Complementary therapies in medicine · 2017
Systematic review5 studies pooledflagCognitive Support forscienceBacopa
- Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.
Kumar N; Abichandani LG; Thawani V; Gharpure KJ; Naidu MU; Venkat Ramana G · Evidence-based complementary and alternative medicine : eCAM · 2024
Randomized trial60 participantsflagCognitive Support forscienceBacopa
- The impact of a rosemary containing drink on event-related potential neural markers of sustained attention.
Riby LM; Edwards S; McDonald H; Moss M · PloS one · 2023
Non-randomized trial48 participantsflagCognitive Support forscienceRosemary
- Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students: A randomized clinical trial.
Nematolahi P; Mehrabani M; Karami-Mohajeri S; Dabaghzadeh F · Complementary therapies in clinical practice · 2018
Randomized trial68 participantsflagCognitive Support forscienceRosemary
- Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
Randomized trial32 participantsflagCognitive Support forscienceTheanine
- Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
Clinical trial20 participantsflagCognitive Support flagMental Focus forscienceTheanine
- Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.
Delfan M; Kordestani-Moghaddam P; Gholami M; Kazemi K; Mohammadi R · Explore (New York, N.Y.) · 2024
Randomized trial62 participantsflagMental Focus forscienceBacopa
- Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modafinil: a review and comparison of effect sizes.
Neale C; Camfield D; Reay J; Stough C; Scholey A · British journal of clinical pharmacology · 2013
Systematic reviewflagMental Focus forscienceBacopa
- Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review.
Al Shahab S; Al Balushi R; Qambar A; Abdulla R; Qader M; Abdulla S; Jahrami H · Nutrients · 2025
Systematic reviewflagMental Focus forscienceBacopa
- Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
Randomized trial24 participantsflagMental Focus forscienceTheanine
- The Effects of a Bacopa monnieri Extract (Bacumen®) on Cognition, Stress, and Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Lopresti AL; Smith SJ · Clinical drug investigation · 2025
Randomized trial101 participantsflagMood Support forscienceBacopa
- Effects of Bacopa monnieri (CDRI 08®) in a population of males exhibiting inattention and hyperactivity aged 6 to 14 years: A randomized, double-blind, placebo-controlled trial.
Kean JD; Downey LA; Sarris J; Kaufman J; Zangara A; Stough C · Phytotherapy research : PTR · 2022
Randomized trial112 participantsflagMood Support forscienceBacopa
- The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects.
Stough C; Lloyd J; Clarke J; Downey LA; Hutchison CW; Rodgers T; Nathan PJ · Psychopharmacology · 2001
Randomized trial85 participantsflagMood Support flagStress Relief forscienceBacopa
- Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
Calabrese C; Gregory WL; Leo M; Kraemer D; Bone K; Oken B · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
Randomized trial54 participantsflagMood Support flagProductivity Boost flagStress Relief forscienceBacopa
- Brahmi for the better? New findings challenging cognition and anti-anxiety effects of Brahmi (Bacopa monniera) in healthy adults.
Sathyanarayanan V; Thomas T; Einöther SJ; Dobriyal R; Joshi MK; Krishnamachari S · Psychopharmacology · 2013
Randomized trial72 participantsflagMood Support forscienceBacopa
- l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
Randomized trial60 participantsflagMood Support forscienceTheanine
- L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
Randomized trial60 participantsflagMood Support flagStress Relief forscienceTheanine
- The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
Systematic review9 studies pooledflagMood Support forscienceTheanine
- Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
Randomized trial168 participantsflagMood Support flagStress Relief forscienceTheanine
- Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
Randomized trial20 participantsflagMood Support forscienceTheanine
- Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial.
Stough C; Downey LA; Lloyd J; Silber B; Redman S; Hutchison C; Wesnes K; Nathan PJ · Phytotherapy research : PTR · 2009
Randomized trial107 participantsflagProductivity Boost forscienceBacopa
- An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance.
Downey LA; Kean J; Nemeh F; Lau A; Poll A; Gregory R; Murray M; Rourke J; Patak B; Pase MP; Zangara A; Lomas J; Scholey A; Stough C · Phytotherapy research : PTR · 2014
Randomized trial24 participantsflagProductivity Boost forscienceBacopa
- Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
Narrative reviewflagProductivity Boost forscienceTheanine
- Efficacy of Brahmi vati in generalised anxiety disorder - Randomized double blind comparative clinical trial.
Khot SG; Tubaki BR; Gonugade VB · Journal of Ayurveda and integrative medicine · 2022
Randomized trial56 participantsflagStress Relief forscienceBacopa
- An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and mood.
Benson S; Downey LA; Stough C; Wetherell M; Zangara A; Scholey A · Phytotherapy research : PTR · 2014
Randomized trial17 participantsflagStress Relief forscienceBacopa
- Herbal remedies for anxiety - a systematic review of controlled clinical trials.
Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2006
Systematic review8 studies pooledflagStress Relief forscienceBacopa
- Comparing the effects of rosemary aromatherapy and music therapy on anxiety levels in patients undergoing general surgery: A randomized controlled clinical trial.
Sayadi Mank-Halati M; Rezaei M; Farzaei MH; Khatony A · Explore (New York, N.Y.) · 2024
Randomized trial236 participantsflagStress Relief forscienceRosemary
- Effects of Olfactory Stimulation with Aroma Oils on Psychophysiological Responses of Female Adults.
Choi NY; Wu YT; Park SA · International journal of environmental research and public health · 2022
Observational study23 participantsflagStress Relief forscienceRosemary
- Effects of visual and aromatic stimulations on the perception of five fundamental tastes.
Itoh M; Kitagawa A; Ouchi H; Yamaguchi M; Watanabe R; Sone H; Kamiyama S · Bioscience, biotechnology, and biochemistry · 2022
Non-randomized trial14 participantsflagStress Relief forscienceRosemary
- Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
Randomized trial34 participantsflagStress Relief forscienceTheanine