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Ultimate Omega-D3 2X Lemon

Nordic Naturals
4.7
★ ★ ★ ★ ★
(594 ratings)
Omega-3 2150 mg
Product Image
Score69
A concentrated omega-3 and vitamin D3 combination for targeted use. Ambiguous EPA/DHA disclosure, premium cost, and dose stacking concerns limit everyday fit.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
Skin Health
Joint Health
Metabolism Boost

Score 69

A concentrated omega-3 and vitamin D3 combination for targeted use. Ambiguous EPA/DHA disclosure, premium cost, and dose stacking concerns limit everyday fit.
How scoring works
$47.56($1.58 per serving)
Daily Vita
$ 47.56
iHerb
$ 47.56
Pure Formulas
$ 47.56
Vitacost
$ 51.17
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Analysis

The serving combines a listed 2,150 mg total omega-3 with 25 mcg vitamin D3. Two softgels provide a concentrated way to combine fatty acids and vitamin D.

EPA, DHA, and other omega-3 entries repeat the same total rather than showing distinct amounts. Source oil, molecular form, oxidation protection, and purity verification are not provided.

It fits adults who intentionally need both a high omega-3 total and vitamin D3. Users already taking vitamin D or seeking routine omega-3 maintenance may find the formula excessive and costly.

Who is it for
  • Adults seeking high-dose omega-3 plus vitamin D3
  • Experienced concentrated-oil users
  • People monitoring total vitamin D intake
Best for
  • Combined high-intake omega-3 and vitamin D
  • Focused two-softgel routines
  • Users who need concentrated delivery

Pros

  • Very high 2,150 mg total
  • Includes 25 mcg vitamin D3
  • Two-softgel serving
  • Lemon flavor may improve tolerance

Cons

  • EPA and DHA amounts are ambiguous
  • Oil source and molecular form are missing
  • Premium recurring cost
  • May duplicate vitamin D
  • More than many maintenance users need

Warnings

  • The high omega-3 intake may increase bruising or bleeding with anticoagulant or antiplatelet medicines
  • Fish-derived oil may be unsuitable for people with a fish allergy; verify the source when it is not stated
  • Fish oil can cause reflux, nausea, or loose stools in some users
  • Count the 25 mcg vitamin D3 amount with other supplements to avoid unintended dose stacking

Nutrient quality

81 Highest impact

The stated omega-3 amount is substantial. EPA and DHA labels are present, but repeated total amounts do not establish a clean fatty-acid breakdown.

Ingredient transparency

63 Moderate impact

EPA and DHA labels are present, but repeated total amounts do not establish a clean fatty-acid breakdown. Complete usage, inactive-ingredient, molecular-form, and purity details remain unavailable.

Customer satisfaction

71 High impact

The supplied aggregate rating and review volume provide a useful satisfaction signal. Specific comments are unavailable, so recurring complaints and purpose-specific experiences cannot be assessed.

Value for money

61 Moderate impact

The active amount partly supports the cost, but disclosure gaps weaken quality-adjusted value. The product is moderately competitive but lacks the disclosure needed for a stronger comparison.

Report analysis

Goals

Skin Health
Impact
High effect
B Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Omega-3 · 2150 mg

Omega-three fatty acids support skin barrier lipids and help regulate inflammatory signaling. The 2,150 mg total amount provides substantial depth for that pathway.

Vitamin D adds general nutritional support but contributes less directly to barrier hydration than the fatty acids. The label gives a total amount but does not clearly separate EPA and DHA or establish molecular form and purity testing.

Study evidence
Omega-3 Supportive 35 studies
Joint Health
Impact
High effect
B+ Goal FitB+ Strength of SupportC CoverageA- Formula Quality
Omega-3 · 2150 mg

High-dose omega-3 supports inflammatory balance, while vitamin D adds general musculoskeletal support. Human evidence supports EPA and DHA for inflammatory pathways, though joint benefits vary by condition.

The 2,150 mg total omega-3 amount is substantial, and 25 mcg vitamin D3 supports daily status. Total omega-3 and vitamin D3 are clear, but EPA and DHA split, molecular form, and purity testing are not clear in the ingredient data.

Study evidence
Omega-3 Supportive 40 studies
Vitamin D Supportive 111 studies
Metabolism Boost
Impact
High effect
D Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Omega-3 · 2150 mgVitamin D · 25 mcg

A substantial omega-3 amount may support lipid handling and metabolic health, but it is not a direct metabolism-boosting active. Vitamin D3 adds nutritional support when status is low but is not a direct thermogenic active.

The total omega-3 quantity is clearly stated, while separate EPA and DHA yields are not provided in the supplied data. The high-potency serving provides depth for omega-3 use but does not add thermogenesis, mitochondrial transport, or targeted glycemic control.

Study evidence
Omega-3 Supportive 42 studies

Ingredients

IngredientAmount per serving
Calories
25 Calorie(s)
Total Fat
2.5 Gram(s)
Vitamin D3 (Cholecalciferol)
25 mcg
Total Omega-3 Fatty Acids (Docosahexaenoic Acid, Eicosapentaenoic Acid, Other Omega-3 Fatty Acids)
2150 mg
Cholesterol
5 mg
Gluten Free Adults 18–50
Report overview
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyA+ Value

The supplied label data separately associates amounts with EPA and DHA and indicates a highly concentrated omega-3 serving. Molecular form, fish source, antioxidant protection, and independent purity verification are not shown, which limits confidence in absorption and freshness. Active-amount cost appears favorable, although the repeated total-omega entries make the fatty-acid breakdown less clear than a conventional EPA and DHA panel.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
    Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
    Randomized trial43 participantsJoint Health forOmega-3
  2. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
    Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
    Randomized trial235 participantsJoint Health forOmega-3
  3. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
    Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
    Meta-analysis1,018 participants18 studies pooledJoint Health forOmega-3
  4. Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
    Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
    Meta-analysis1,420 participants30 studies pooledJoint Health forOmega-3
  5. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
    Goldberg RJ; Katz J · Pain · 2007
    Meta-analysis17 studies pooledJoint Health forOmega-3
  6. Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis.
    Wang X; Cicuttini F; Jin X; Wluka AE; Han W; Zhu Z; Blizzard L; Antony B; Winzenberg T; Jones G; Ding C · Osteoarthritis and cartilage · 2018
    Randomized trial413 participantsJoint Health forVitamin D
  7. Vitamin D Deficiency Leads to Poorer Health Outcomes and Greater Length of Stay After Total Knee Arthroplasty and Supplementation Improves Outcomes: A Systematic Review and Meta-Analysis.
    Vivek K; Kamal R; Perera E; Gupte CM · JBJS reviews · 2024
    Meta-analysis146,054 participants10 studies pooledJoint Health forVitamin D
  8. Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis.
    Zhao ZX; He Y; Peng LH; Luo X; Liu M; He CS; Chen J · Aging clinical and experimental research · 2021
    Meta-analysis1,599 participants6 studies pooledJoint Health forVitamin D
  9. Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.
    Wang T; Zheng S; Jin X; Cen H; Zhu Z; Han W; Wluka A; Cicuttini F; Cao P; Ding C · Rheumatology advances in practice · 2025
    Randomized trial413 participantsJoint Health forVitamin D
  10. The Efficacy and Safety of Disease-Modifying Osteoarthritis Drugs for Knee and Hip Osteoarthritis-a Systematic Review and Network Meta-Analysis.
    Yang W; Sun C; He SQ; Chen JY; Wang Y; Zhuo Q · Journal of general internal medicine · 2021
    Meta-analysis11,890 participants28 studies pooledJoint Health forVitamin D
  11. Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
    Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
    Meta-analysis331 participants6 studies pooledMetabolism Boost forOmega-3
  12. Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
    Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
    Randomized trial38 participantsMetabolism Boost forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsMetabolism Boost Skin Health forOmega-3
  14. The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
    Randomized trial60 participantsMetabolism Boost forOmega-3
  15. A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
    Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
    Randomized trial200 participantsMetabolism Boost forOmega-3
  16. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  17. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  18. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  19. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3