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ATP Cofactors

Optimox
4.8
★ ★ ★ ★ ★
(1093 ratings)
Niacin 500 mg
Riboflavin 100 mg
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Score95

A potent B2 and B3 combination designed for mitochondrial support and heart health without the niacin flush.

How scoring works
Quantity:90 Tablet(s) • (90 servings)
Goals:
Cardiovascular Support
Heart Health
Skin Health

Score 95

A potent B2 and B3 combination designed for mitochondrial support and heart health without the niacin flush.

How scoring works
$34.99($0.38 per serving)
iHerb
$ 34.99
Pure Formulas
$ 34.99
iHerb
$ 34.99
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Analysis

This formula uses inositol hexanicotinate, a form of niacin that provides the benefits of B3 without the uncomfortable skin flushing. It is specifically designed to support the mitochondria in producing ATP, the body's primary fuel.

The 100mg of riboflavin works together with niacin to support vascular health and neutralize free radicals. This is a very focused supplement for individuals who want specific support for their heart and energy pathways.

Pros

  • High 500mg dose of no-flush Niacin
  • Simple, targeted energy formula
  • Supports cardiovascular integrity
  • Cost-effective for specialized support

Cons

  • Only contains two vitamins
  • Tablet form
  • Niacin dose may be too high for some

Warnings

  • Monitor for any rare skin reactions
  • Consult a professional if taking heart medications

Nutrient quality

94 Highest impact

The use of inositol hexanicotinate provides a reliable no-flush niacin source with high biological utilization. Meaningful doses of both B2 and B3 support the foundational energy requirements of cardiovascular tissues.

Ingredient transparency

96 Highest impact

The label provides specific doses and technical names for both active ingredients, ensuring clarity for the consumer. Labeling is straightforward, although the chemical form for riboflavin is not precisely specified.

Customer satisfaction

96 Highest impact

A high average rating over one thousand reviews confirms consistent product quality and user trust. Consumers frequently report improved energy levels and the excellent tolerability of the no-flush niacin form.

Value for money

93 Highest impact

At 38 cents per serving, this targeted formula offers solid value for its high-dose active ingredients. The quality and tolerability of the niacin form justify the price for daily cardiovascular and energy support.

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Goals

Cardiovascular Support
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality

This energy-focused complex delivers a potent 500mg dose of no-flush niacin and high-dose riboflavin to support metabolic and cardiovascular integrity. Niacin appears well aligned with clinical protocols for supporting healthy lipid metabolism and vascular function without the discomfort of a typical flush.

Meaningful support for cardiac energy and circulatory health is achieved through this focused B-vitamin blend. The single-ingredient approach ensures high functional depth for the metabolic pathways critical to heart health.

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Heart Health
Impact
Highest effect
A Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality

Niacin as inositol hexanicotinate supports healthy lipid levels and vascular integrity without the flush effect. This formulation pairs Vitamin B3 with Vitamin B2 to support efficient energy production in the cardiovascular system.

Inositol hexanicotinate acts as a well-tolerated source of niacin for managing long-term heart health. The 500mg dose appears well aligned with therapeutic goals for lipid support and metabolic efficiency.

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Skin Health
Impact
Moderate effect
D Goal FitC+ Strength of SupportD CoverageB Formula Quality

This formula provides high doses of riboflavin and niacin to support cellular energy production and metabolic health. While these B-vitamins are essential for skin cell turnover, the specific form of niacin used is less targeted for direct skin barrier improvement.

Inositol hexanicotinate is a 'no-flush' form of B3 that may be better suited for metabolic goals than for the specific dermal benefits associated with niacinamide. The high riboflavin content serves as a supportive cofactor but does not address primary skin concerns like hydration or structural integrity.

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Ingredients

IngredientAmount per serving
Riboflavin
100 mg
Niacin (Inositol Hexanicotinate)
 500 mg
Adults 18–50 Dairy Free Sugar Free
Report overview
Niacin (Inositol Hexanicotinate) · 500 mg OverallScore79
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
ATP Cofactors uses high-dose no-flush niacin to specifically support energy production. It provides a targeted concentration of B2 and B3 in a simple tablet format.
View ingredientView products
Riboflavin · 100 mg OverallScore70
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
This targeted formula provides a high dose of riboflavin for energy production in a reliable tablet format. It is a straightforward and reasonably priced choice for metabolic support, though capsule options offer better bioavailability.
View ingredientView products
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