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Super B-Complex

Nature Made
4.7
★ ★ ★ ★ ★
(4079 ratings)
Thiamin 100 mg
Niacin 25 mg
Folate 400 mcg
Riboflavin 20 mg
Product Image
Score81
Complete coverage, one-tablet convenience, and strong value make this a good basic B complex. Its main compromise is reliance on standard rather than active vitamin forms.
How scoring works
Quantity:160 Tablet(s) • (160 servings)
Goals:
General Health
Energy
Hair Health

Score 81

Complete coverage, one-tablet convenience, and strong value make this a good basic B complex. Its main compromise is reliance on standard rather than active vitamin forms.
How scoring works
$10.98($0.06 per serving)
Walmart
$ 10.98
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Analysis

The one-tablet formula combines a complete B complex with 150 mg of vitamin C. Thiamine is especially substantial, while niacinamide, riboflavin, B6, folate, B12, biotin, and pantothenic acid provide broad metabolic coverage.

The ingredient choices are dependable but conventional. Folic acid, cyanocobalamin, and pyridoxine hydrochloride work for routine nutrition, yet people specifically seeking active forms will not find them here.

A low B6 amount avoids the main long-term concern seen in many high-potency B complexes. The straightforward serving and strong value make it well suited to basic daily use rather than targeted correction of a diagnosed deficiency.

Who is it for
  • Adults wanting a simple one-tablet B complex
  • People seeking B vitamins with vitamin C
  • Value-focused users who do not require active forms
Best for
  • General B-vitamin maintenance
  • Routine energy-metabolism support
  • Convenient low-cost daily use

Pros

  • Provides a complete B-vitamin profile
  • Adds 150 mg of vitamin C
  • Keeps vitamin B6 at a moderate amount
  • Requires only one tablet daily

Cons

  • Uses folic acid instead of methylfolate
  • Uses cyanocobalamin for vitamin B12
  • Uses conventional pyridoxine for vitamin B6
  • Biotin and pantothenic acid are modest

Nutrient quality

74 High impact

The formula uses conventional folic acid, pyridoxine hydrochloride, cyanocobalamin, and thiamine mononitrate. Thiamine is unusually high, while the other listed amounts are generally measured.

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Ingredient transparency

86 Highest impact

Specific amounts are supplied for every listed active ingredient. No proprietary blend hides the listed doses.

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Customer satisfaction

71 High impact

The supplied aggregate rating is very strong. No complaint themes or purpose-specific experience details are supplied.

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Value for money

92 Highest impact

The formula and favorable qualitative positioning support strong value. Added vitamin C is useful, while calcium contributes little to the core purpose.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitB Strength of SupportB CoverageA Formula Quality
Folate · 400 mcgVitamin B12 · 15 mcgVitamin C · 150 mg

A broad set of B vitamins supports energy metabolism, methylation, and routine nutritional coverage. Vitamin C adds antioxidant and collagen support, while every active amount is clearly stated.

Most doses are meaningful, but folic acid and cyanocobalamin are less direct forms than methylfolate and methylcobalamin. The formula is useful for focused vitamin coverage rather than comprehensive general wellness because it provides little mineral or essential-fat support.

Study evidence
Folate Supportive 80 studies
Vitamin C Supportive 56 studies
Energy
Energy
Impact
High effect
A- Goal FitB- Strength of SupportC+ CoverageA Formula Quality
Vitamin B5 · 5.5 mgRiboflavin · 20 mgThiamin · 100 mgVitamin B12 · 15 mcg

Thiamine, riboflavin, niacin, and other B vitamins directly support conversion of food into cellular energy. High thiamine and riboflavin amounts make the formula more substantial than a low-dose multivitamin.

Most forms are basic rather than coenzyme forms, and the B12 amount is modest for targeted higher-needs support. The formula can address inadequate B-vitamin intake but is not an acute stimulant.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Hair Health
Hair Health
Impact
Moderate effect
D+ Goal FitC Strength of SupportD CoverageC Formula Quality
Biotin · 30 mcgVitamin C · 150 mg

Folate and B12 may support follicle cell division and oxygen delivery when intake is inadequate. The formula offers little direct support for keratin structure, mineral balance, or follicle cycling.

Folate is present at a meaningful amount, but B12 and biotin are modest and use ordinary forms. High thiamine and other B-vitamin amounts add little evidence-based hair value.

Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 150 mg
Thiamine (Thiamine Mononitrate)
 100 mg
Riboflavin
20 mg
Niacin (Niacinamide)
 25 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 2 mg
Folic Acid
400 mcg
Vitamin B12 (Cyanocobalamin)
 15 mcg
Biotin
30 mcg
Pantothenic Acid (D-Calcium Pantothenate)
 5.5 mg
Calcium (Dibasic Calcium Phosphate)
 35 mg
Gluten Free Adults 18–50
Report overview
Thiamin (Thiamine Mononitrate) · 100 mg OverallScore88
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Thiamine mononitrate delivers a clearly labeled high-potency amount as part of a broader B-complex. The tablet format is conventional and lacks enough excipient detail for a full purity review. A low serving cost paired with substantial thiamine makes it especially cost-efficient.

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Niacin (Niacinamide) · 25 mg OverallScore84
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

The B-complex clearly provides niacinamide at a practical routine dose. That form is suitable for general vitamin support and has less flushing concern than nicotinic acid, although it is not intended for lipid modification. The low serving cost is a meaningful strength, while the ordinary tablet lacks specialized release technology.

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Folate · 400 mcg OverallScore48
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyC Value

Synthetic folic acid supplies folate but requires conversion before the body can use it. The listed amount is aligned with the preferred intake range. Vitamin B12 is included at a dose that supports the stated co-supplementation safeguard. A low serving cost improves its practical value.

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Loading alternative details
81 Performance

B Complex

Thompson
<p>A broad B-complex includes all core B vitamins plus modest choline, while conventional forms and a high niacin amount keep it basic. Compared with the original, the broader coverage, clearer forms, or more purposeful nutrient profile offers a meaningful quality advantage, subject to the stated trade-off.</p>
78 Performance

B-50 Complex

21st Century
<p>The complete B-50 profile is clearly disclosed, but conventional forms and a high pyridoxine amount reduce its fit for long-term daily use. Compared with the original, the broader coverage, clearer forms, or more purposeful nutrient profile offers a meaningful quality advantage, subject to the stated trade-off.</p>
79 Performance

ATP Cofactors

Optimox
<p>Substantial riboflavin and inositol hexanicotinate provide focused B2 and non-flushing B3 support, though this is not a complete B-complex. Compared with the original, the broader coverage, clearer forms, or more purposeful nutrient profile offers a meaningful quality advantage, subject to the stated trade-off.</p>
80 Budget

Super Vitamin B-Complex

Spring Valley
<p>The formula covers the core B vitamins plus vitamin C at clearly measured amounts, but the chemical forms are not provided and thiamine is unusually high. Its lower serving cost improves everyday economy compared with the original, with the noted coverage or form limitations.</p>
79 Budget

Super Vitamin B-Complex

Spring Valley
<p>The formula covers the core B vitamins plus vitamin C at clearly measured amounts, but the chemical forms are not provided and thiamine is unusually high. Its lower serving cost improves everyday economy compared with the original, with the noted coverage or form limitations.</p>
80 Budget

B-Complex plus Vitamin C

21st Century
<p>Vitamin C, thiamine, riboflavin, niacinamide, vitamin B6, and pantothenic acid are clearly disclosed, but folate, vitamin B12, and biotin are absent. Its serving cost is roughly equal to the original rather than cheaper; it is included because fewer than three eligible candidates cost less.</p>
71 Value

B 50 Complex

Thompson
<p>A full B-50 profile provides substantial amounts of the core B vitamins, but the undisclosed base blend and high pyridoxine amount limit long-term appeal. The complete or clearly disclosed B-vitamin profile provides a practical quality-to-cost balance compared with the original, while the conventional forms and dosing cautions remain relevant.</p>
74 Value

B 50 Complex

Spring Valley
<p>A complete B-50 profile is inexpensive and broadly dosed, but none of the chemical forms are disclosed and pyridoxine is high. The complete or clearly disclosed B-vitamin profile provides a practical quality-to-cost balance compared with the original, while the conventional forms and dosing cautions remain relevant.</p>
77 Value

B-Complex with C

Mason Natural
<p>Vitamin C and six B vitamins are supplied in clearly identified conventional forms, but folate, vitamin B12, and biotin are missing. The complete or clearly disclosed B-vitamin profile provides a practical quality-to-cost balance compared with the original, while the conventional forms and dosing cautions remain relevant.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  12. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  13. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  14. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  15. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  16. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  17. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  18. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  19. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  20. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  21. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  22. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  23. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  24. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  25. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  26. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate
  27. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  28. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  29. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate