Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Rhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trial.
Punja S; Shamseer L; Olson K; Vohra S · PloS one · 2015
Randomized trial48 participantsflagEnergy forscienceRhodiola
- Scientific Opinion on the substantiation of a health claim related to Rhodiola rosea L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagEnergy forscienceRhodiola
- Rhodiola rosea for physical and mental fatigue: a systematic review.
Ishaque S; Shamseer L; Bukutu C; Vohra S · BMC complementary and alternative medicine · 2013
Systematic review11 studies pooledflagEnergy forscienceRhodiola
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
Randomized trial48 participantsflagEnergy forscienceRhodiola
- The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
Randomized trial18 participantsflagEnergy forscienceRhodiola
- The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
Clinical trial10 participantsflagEnergy forscienceRhodiola
- Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
Single-arm trial100 participantsflagEnergy forscienceRhodiola
- Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
Randomized trial59 participantsflagBrain Health flagCognitive Support flagEnergy forscienceAshwagandha
- Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
Randomized trial40 participantsflagBrain Health flagCognitive Support flagMental Focus forscienceAshwagandha
- Efficacy of Withania somnifera supplementation on adult's cognition and mood.
Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
Randomized trial60 participantsflagBrain Health flagCognitive Support flagProductivity Boost forscienceAshwagandha
- A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
Randomized trial85 participantsflagBrain Health flagMental Focus forscienceAshwagandha
- Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
Randomized trial130 participantsflagBrain Health forscienceAshwagandha
- Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis.
Tiemtad P; Ingkaninan K; Temkitthawon P; Thimkorn P; Rattanachaisit N; Teaktong T; Dhippayom T · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
Meta-analysis2,107 participants29 studies pooledflagBrain Health flagMental Focus forscienceBacopa
- Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
Kongkeaw C; Dilokthornsakul P; Thanarangsarit P; Limpeanchob N; Norman Scholfield C · Journal of ethnopharmacology · 2014
Meta-analysis518 participants9 studies pooledflagBrain Health flagMental Focus flagProductivity Boost forscienceBacopa
- Comparative efficacy of Medhya Rasayana,Bacopa monnieri, and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: A prakriti-based double-blind, randomized controlled trial.
Verma J; Rathi R; Anamika; Rathi B; Pandey VB · Journal of Ayurveda and integrative medicine · 2025
Randomized trial180 participantsflagBrain Health flagCognitive Support forscienceBacopa
- Plant-derived nootropics and human cognition: A systematic review.
Lorca C; Mulet M; Arévalo-Caro C; Sanchez MÁ; Perez A; Perrino M; Bach-Faig A; Aguilar-Martínez A; Vilella E; Gallart-Palau X; Serra A · Critical reviews in food science and nutrition · 2023
Systematic review256 studies pooledflagBrain Health forscienceBacopa
- The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
Feng X; Fan S; Wei F · Frontiers in pharmacology · 2026
Meta-analysis1,861 participants25 studies pooledflagBrain Health flagCognitive Support forscienceBacopa
- Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
Randomized trial27 participantsflagBrain Health flagMental Focus forscienceRhodiola
- A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
Randomized trial100 participantsflagBrain Health forscienceRhodiola
- Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
Narrative reviewflagBrain Health forscienceRhodiola
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
Randomized trial56 participantsflagBrain Health flagProductivity Boost forscienceRhodiola
- Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
Single-arm trial50 participantsflagBrain Health flagCognitive Support forscienceRhodiola
- A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
Randomized trial54 participantsflagCognitive Support flagMental Focus forscienceAshwagandha
- Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
Randomized trial58 participantsflagCognitive Support flagMental Focus forscienceAshwagandha
- The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
Pase MP; Kean J; Sarris J; Neale C; Scholey AB; Stough C · Journal of alternative and complementary medicine (New York, N.Y.) · 2012
Systematic review6 studies pooledflagCognitive Support flagProductivity Boost forscienceBacopa
- A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations.
Kean JD; Downey LA; Stough C · Complementary therapies in medicine · 2017
Systematic review5 studies pooledflagCognitive Support forscienceBacopa
- Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.
Kumar N; Abichandani LG; Thawani V; Gharpure KJ; Naidu MU; Venkat Ramana G · Evidence-based complementary and alternative medicine : eCAM · 2024
Randomized trial60 participantsflagCognitive Support forscienceBacopa
- Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
Panossian A; Wikman G · Current clinical pharmacology · 2009
Narrative reviewflagCognitive Support flagMental Focus forscienceRhodiola
- Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
Clinical trial112 participantsflagCognitive Support forscienceRhodiola
- Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
Systematic review19 studies pooledflagCognitive Support forscienceRhodiola
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
Randomized trial60 participantsflagCognitive Support flagProductivity Boost forscienceRhodiola
- Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
Randomized trial186 participantsflagEnergy forscienceAshwagandha
- Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
Randomized trialflagEnergy forscienceAshwagandha
- Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
Vittal M; Vinciguerra M · Biogerontology · 2025
Narrative reviewflagEnergy forscienceAshwagandha
- Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
Randomized trial120 participantsflagEnergy flagProductivity Boost forscienceAshwagandha
- Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
Randomized trial24 participantsflagEnergy flagMental Focus forscienceRhodiola
- Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
Randomized trial96 participantsflagEnergy forscienceRhodiola
- Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
Randomized trial30 participantsflagEnergy forscienceRhodiola
- Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
Randomized trial50 participantsflagMental Focus forscienceAshwagandha
- Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.
Delfan M; Kordestani-Moghaddam P; Gholami M; Kazemi K; Mohammadi R · Explore (New York, N.Y.) · 2024
Randomized trial62 participantsflagMental Focus forscienceBacopa
- Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modafinil: a review and comparison of effect sizes.
Neale C; Camfield D; Reay J; Stough C; Scholey A · British journal of clinical pharmacology · 2013
Systematic reviewflagMental Focus forscienceBacopa
- Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review.
Al Shahab S; Al Balushi R; Qambar A; Abdulla R; Qader M; Abdulla S; Jahrami H · Nutrients · 2025
Systematic reviewflagMental Focus forscienceBacopa
- The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
Systematic review11 studies pooledflagMental Focus forscienceRhodiola
- Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
Randomized trial26 participantsflagMental Focus flagProductivity Boost forscienceRhodiola
- Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
Meta-analysis400 participants5 studies pooledflagProductivity Boost forscienceAshwagandha
- Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
Randomized trial80 participantsflagProductivity Boost forscienceAshwagandha
- Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
Randomized trial20 participantsflagProductivity Boost forscienceAshwagandha
- Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
Calabrese C; Gregory WL; Leo M; Kraemer D; Bone K; Oken B · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
Randomized trial54 participantsflagProductivity Boost forscienceBacopa
- Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial.
Stough C; Downey LA; Lloyd J; Silber B; Redman S; Hutchison C; Wesnes K; Nathan PJ · Phytotherapy research : PTR · 2009
Randomized trial107 participantsflagProductivity Boost forscienceBacopa
- An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance.
Downey LA; Kean J; Nemeh F; Lau A; Poll A; Gregory R; Murray M; Rourke J; Patak B; Pase MP; Zangara A; Lomas J; Scholey A; Stough C · Phytotherapy research : PTR · 2014
Randomized trial24 participantsflagProductivity Boost forscienceBacopa
- A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
Randomized trialflagProductivity Boost forscienceRhodiola
- The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
Narrative reviewflagProductivity Boost forscienceRhodiola