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Full Spectrum St. John's Wort Extract 600 mg

Planetary Herbals
4.5
★ ★ ★ ★ ★
(248 ratings)
St. John's Wort 500 mg
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Score81
An exceptionally affordable, high-potency 600 mg extract standardized to 0.3% hypericins, offering robust daily support for emotional resilience and mood.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
Mood Support

Score 81

An exceptionally affordable, high-potency 600 mg extract standardized to 0.3% hypericins, offering robust daily support for emotional resilience and mood.
How scoring works
$9.43($0.15 per serving)
Pure Formulas
$ 23.45
Amazon
$ 0.00
iHerb
$ 11.73
Vitacost
$ 9.43
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Analysis

Each tablet of Planetary Herbals Full Spectrum St. John's Wort delivers a potent 600 mg dose of extract. This concentration is particularly effective as it is standardized to 0.3% hypericins, yielding at least 1.5 mg of the active marker per tablet. This level of transparency and potency aligns well with dosages used in clinical research for mood regulation and emotional stability.

The 'Full Spectrum' approach combines this standardized extract with additional aerial parts, ensuring users benefit from the plant's natural chemical synergy alongside the concentrated actives. At one tablet per serving, it offers a more convenient and intensive intervention than standard 300 mg alternatives.

The manufacturing quality is reliable, and the product stands out for its value. Despite the higher potency and standardization, the price per serving remains very low. This makes it an ideal choice for long-term daily support, provided users are aware of the common herb-drug interactions associated with St. John's Wort.

Who is it for
  • Adults seeking a standardized St. John’s wort tablet
  • Users who have screened the herb against medicines and mood history
Best for
  • Clearly defined hypericin delivery
  • A substantial one-tablet St. John’s wort serving

Pros

  • Main extract is standardized to 0.3% hypericin
  • Substantial 600 mg total amount
  • One tablet per serving
  • Focused formula
  • Favorable serving value

Cons

  • Hyperforin is not disclosed
  • Added calcium is not relevant to the intended use
  • Tablet may not suit users who prefer capsules

Warnings

  • Do not combine St. John’s wort with SSRI, SNRI, MAOI, or other serotonergic medicines because serotonin toxicity can occur.
  • St. John’s wort can reduce the effectiveness of oral contraceptives, warfarin, transplant medicines, some HIV medicines, and several seizure medicines.
  • The herb can increase sensitivity to sunlight, so extra sun protection may be needed.
  • People with bipolar disorder should avoid unsupervised use because St. John’s wort can trigger agitation or mania.

Nutrient quality

87 Highest impact

A standardized extract and substantial amount provide strong ingredient quality for focused mood support. The dose remains plausible, while the small calcium addition has little effect on the formula.

Ingredient transparency

78 High impact

The shown active amounts are generally clear, with no proprietary blend obscuring the main doses. Daily directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

67 High impact

The supplied aggregate rating is favorable and supported by a useful review volume. Detailed feedback is unavailable, so repeated complaints and fit with the intended use cannot be judged.

Value for money

92 Highest impact

The formula provides strong practical value for its quality and serving profile. Few low-value additions dilute the core formula.

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Goals

Mood Support
Mood Support
Impact
Highest effect
A Goal FitA- Strength of SupportC- CoverageA Formula Quality

Full Spectrum St. John's Wort Extract 600 mg provides 600 mg per serving and uses a clearly standardized St. John's wort extract, giving it direct but dose-dependent alignment with mood support.

Customer feedback averages 4.51 from 248 reviews, while the published label carries medication-interaction cautions and a product-specific independent certification was not confirmed.

Study evidence
St. John's Wort Supportive 97 studies

Ingredients

IngredientAmount per serving
Calcium (Dibasic Calcium Phosphate)
 31 mg
St. John's Wort aerial parts extract
500 mg
St. John's Wort aerial parts extract
100 mg
Adults 18–50
Report overview
St. John's Wort · 500 mg OverallScore95
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Planetary Herbals Full Spectrum Saint John's Wort Extract provides 600 mg per serving and uses a blend led by 500 mg of extract standardized to 0.3% hypericins, producing a strong dosage fit under the collection rubric. Customer feedback averages 4.51 from 248 reviews, while the published label includes a specific interaction warning.

View ingredientView products
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84 Performance

Feeling Positive St. John's Wort 300 mg

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Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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St. John's Wort Extract 300 mg

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A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

Perika St. John's Wort

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The named extract supports consistent quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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St. John's Wort Extract

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Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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St. John's Wort 300 mg

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Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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St. John's Wort 300 mg

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A hypericin-standardized extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
87 Value

St. John's Wort Extract 300 mg

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A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

St. John's Wort 300 mg

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Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Value

St. John's Wort

Paradise
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression: a randomized double-blind trial in a Brazilian sample.
    Moreno RA; Teng CT; Almeida KM; Tavares Junior H · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2006
    Randomized trial72 participantsMood Support forSt. John's Wort
  2. The impact of missing data on clinical trials: a re-analysis of a placebo controlled trial of Hypericum perforatum (St Johns wort) and sertraline in major depressive disorder.
    Grobler AC; Matthews G; Molenberghs G · Psychopharmacology · 2014
    Randomized trial340 participantsMood Support forSt. John's Wort
  3. Documentary Analysis of Hypericum perforatum (St. John's Wort) and Its Effect on Depressive Disorders.
    Otero MC; Ceric F; Miranda-Rojas S; Carreño C; Escares R; Escobar MJ; Saracini C; Atala C; Ramírez-Barrantes R; Gordillo-Fuenzalida F · Pharmaceuticals (Basel, Switzerland) · 2025
    Narrative reviewMood Support forSt. John's Wort
  4. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  5. St John's wort for depression--an overview and meta-analysis of randomised clinical trials.
    Linde K; Ramirez G; Mulrow CD; Pauls A; Weidenhammer W; Melchart D · BMJ (Clinical research ed.) · 1996
    Meta-analysis1,757 participants23 studies pooledMood Support forSt. John's Wort
  6. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  7. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  8. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort
  9. [Meta-analysis of effectiveness and tolerability of treatment of mild to moderate depression with St. John's Wort].
    Röder C; Schaefer M; Leucht S · Fortschritte der Neurologie-Psychiatrie · 2004
    Meta-analysis30 studies pooledMood Support forSt. John's Wort
  10. A meta-analysis on the efficacy and safety of St John's wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults.
    Cui YH; Zheng Y · Neuropsychiatric disease and treatment · 2016
    Meta-analysis3,126 participants27 studies pooledMood Support forSt. John's Wort
  11. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort