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St. John's Wort 300 mg

California Gold Nutrition EuroHerbs
4.6
★ ★ ★ ★ ★
(5747 ratings)
St. John's Wort 300 mg
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Score84

Standardized Euromed extract, one capsule, and a large supply make this the strongest package value. Extensive interaction risks still govern suitability.

How scoring works
Quantity:180 Capsule(s) • (180 servings)
Goals:
Mood Support
Stress Relief

Score 84

Standardized Euromed extract, one capsule, and a large supply make this the strongest package value. Extensive interaction risks still govern suitability.

How scoring works
$14.00($0.07 per serving)
Amazon
$ 19.13
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$ 14.00
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Analysis

Each capsule supplies 300 mg of Euromed St. John’s wort extract standardized to 0.3% hypericin. Prior scoring information also identifies flowering tops as the source material.

The single-active formula offers direct, consistent mood support without blend ambiguity. It remains a situational stress option rather than broad coverage for sleep, relaxation, or physical stress symptoms.

A 180-serving supply provides strong convenience and value for established users. New users should not let the bulk format encourage use before medication, bipolar-history, and photosensitivity risks have been reviewed.

Who is it for
  • Established users of standardized St. John’s wort
  • Adults with no conflicting medicines or bipolar-spectrum history
Best for
  • Bulk value for Euromed extract
  • Consistent 0.3% hypericin delivery

Pros

  • Euromed standardized extract
  • 0.3% hypericin disclosure
  • One capsule per serving
  • Large 180-serving supply
  • Excellent qualitative value

Cons

  • Hyperforin is not disclosed
  • Bulk bottle is a long commitment
  • Limited breadth for general stress relief

Warnings

  • Do not combine St. John’s wort with SSRI, SNRI, MAOI, or other serotonergic medicines because serotonin toxicity can occur.
  • St. John’s wort can reduce the effectiveness of oral contraceptives, warfarin, transplant medicines, some HIV medicines, and several seizure medicines.
  • The herb can increase sensitivity to sunlight, so extra sun protection may be needed.
  • People with bipolar disorder should avoid unsupervised use because St. John’s wort can trigger agitation or mania.

Nutrient quality

86 Highest impact

A hypericin-standardized extract provides strong form quality and direct mood relevance. The moderate amount is not excessive, though it may represent only a partial daily dose.

Ingredient transparency

80 Highest impact

The shown active amounts are generally clear, with no proprietary blend obscuring the main doses. Daily directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

72 High impact

The supplied aggregate rating is favorable and supported by a very large review volume. Detailed feedback is unavailable, so repeated complaints and fit with the intended use cannot be judged.

Value for money

97 Highest impact

The formula provides strong practical value for its quality and serving profile. Few low-value additions dilute the core formula.

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Goals

Mood Support
Impact
High effect
A Goal FitB Strength of SupportD CoverageA Formula Quality

St. John's Wort 300 mg provides 300 mg per serving and uses a clearly standardized St. John's wort extract, giving it direct but dose-dependent alignment with mood support.

Customer feedback averages 4.58 from 5712 reviews, while the published label carries medication-interaction cautions and the listing identifies an FDA-registered, third-party-audited cGMP-compliant facility.

Study evidence
St. John's Wort Supportive 97 studies
Stress Relief
Impact
High effect
C- Goal FitC+ Strength of SupportD CoverageA Formula Quality

California Gold Nutrition EuroHerbs St. John's Wort 300 mg, 180 capsules supplies 300 mg of St. John's wort in a Euromed flowering-tops extract standardized to 0.3% hypericin, offering a focused but situational route to stress-related emotional balance.

Supplied feedback averages 4.58 across 5,712 reviews, while published safety information makes medication-interaction and photosensitivity review important before use.

Study evidence
St. John's Wort Mixed 6 studies

Ingredients

IngredientAmount per serving
St. John's Wort Extract (Hypericin)
300 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyA+ Value

California Gold Nutrition EuroHerbs Saint John's Wort, 180 capsules provides 300 mg per serving and uses a Euromed flowering-tops extract standardized to 0.3% hypericin, producing a partial dosage fit under the collection rubric. Customer feedback averages 4.58 from 5712 reviews, while the published label includes a specific interaction warning.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression: a randomized double-blind trial in a Brazilian sample.
    Moreno RA; Teng CT; Almeida KM; Tavares Junior H · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2006
    Randomized trial72 participantsMood Support forSt. John's Wort
  2. The impact of missing data on clinical trials: a re-analysis of a placebo controlled trial of Hypericum perforatum (St Johns wort) and sertraline in major depressive disorder.
    Grobler AC; Matthews G; Molenberghs G · Psychopharmacology · 2014
    Randomized trial340 participantsMood Support forSt. John's Wort
  3. Documentary Analysis of Hypericum perforatum (St. John's Wort) and Its Effect on Depressive Disorders.
    Otero MC; Ceric F; Miranda-Rojas S; Carreño C; Escares R; Escobar MJ; Saracini C; Atala C; Ramírez-Barrantes R; Gordillo-Fuenzalida F · Pharmaceuticals (Basel, Switzerland) · 2025
    Narrative reviewMood Support forSt. John's Wort
  4. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  5. St John's wort for depression--an overview and meta-analysis of randomised clinical trials.
    Linde K; Ramirez G; Mulrow CD; Pauls A; Weidenhammer W; Melchart D · BMJ (Clinical research ed.) · 1996
    Meta-analysis1,757 participants23 studies pooledMood Support forSt. John's Wort
  6. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  7. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  8. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort
  9. [Meta-analysis of effectiveness and tolerability of treatment of mild to moderate depression with St. John's Wort].
    Röder C; Schaefer M; Leucht S · Fortschritte der Neurologie-Psychiatrie · 2004
    Meta-analysis30 studies pooledMood Support forSt. John's Wort
  10. A meta-analysis on the efficacy and safety of St John's wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults.
    Cui YH; Zheng Y · Neuropsychiatric disease and treatment · 2016
    Meta-analysis3,126 participants27 studies pooledMood Support forSt. John's Wort
  11. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  12. Comparison of St John's wort and imipramine for treating depression: randomised controlled trial.
    Woelk H · BMJ (Clinical research ed.) · 2000
    Randomized trial324 participantsStress Relief forSt. John's Wort
  13. Differential therapy of mild to moderate depressive episodes (ICD-10 F 32.0; F 32.1) with St. John's wort.
    Friede M; Henneicke von Zepelin HH; Freudenstein J · Pharmacopsychiatry · 2002
    Randomized trial240 participantsStress Relief forSt. John's Wort
  14. Kava and St. John's Wort: current evidence for use in mood and anxiety disorders.
    Sarris J; Kavanagh DJ · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
    Systematic reviewStress Relief forSt. John's Wort
  15. Do early changes in the HAM-D-17 anxiety/somatization factor items affect the treatment outcome among depressed outpatients? Comparison of two controlled trials of St John's wort (Hypericum perforatum) versus a SSRI.
    Bitran S; Farabaugh AH; Ameral VE; LaRocca RA; Clain AJ; Fava M; Mischoulon D · International clinical psychopharmacology · 2012
    Other475 participantsStress Relief forSt. John's Wort
  16. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
    Lakhan SE; Vieira KF · Nutrition journal · 2011
    Systematic review2,619 participants24 studies pooledStress Relief forSt. John's Wort