St. John's Wort 450
Source Naturals
St. John's Wort 450
4.4
★ ★ ★ ★ ★
(402 ratings)
St. John's Wort 450 mg
Score 65.0
A reliable, affordable whole herb St. John's Wort from a respected brand, offering good value for long-term use, though it lacks extract standardization.
Quantity: 180 Tablet(s)Servings size: 1 Tablet(s) (180 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 65.0
A reliable, affordable whole herb St. John's Wort from a respected brand, offering good value for long-term use, though it lacks extract standardization.
insights Analysis
Source Naturals is a reputable brand known for its diverse range of supplements. This product offers 450mg of whole herb St. John's Wort per serving in a large 180-count bottle, leading to a very competitive price per serving ($0.12). While it is a whole herb product and not a standardized extract, its excellent value for a widely recognized brand makes it an attractive option for budget-conscious consumers seeking general St. John's Wort benefits. The moderate review count is positive but not as high as the market leaders.
- Reputable brand
- Excellent price per serving for a large quantity
- Good dosage for a whole herb product
- Not a standardized extract, so potency may vary
- St. John's Wort can interact with numerous medications, including antidepressants, birth control, and blood thinners. Consult a healthcare professional before use, especially if on other medications.
- Photosensitivity may occur.
$20.51($0.11 per serving)
 iHerb | $ 20.51 | |
 Amazon | $ 27.79 |
bolt Effectiveness for goals
Some research suggests St. John's Wort may be effective for mild to moderate depression. Its use for severe depression is not well-supported by evidence. Consultation with a healthcare professional is advisable before considering use.
For mild to moderate depression, some studies suggest St. John's Wort can be similarly effective to certain conventional antidepressants. However, it may have a different side effect profile and significant drug interactions. This comparison does not extend to all types or severities of depression.
Scientific research indicates that St. John's Wort extracts can be effective for treating mild to moderate depression, often showing comparable efficacy to some standard antidepressants. However, results can vary depending on the extract used and the specific study design. Research on its effectiveness for other conditions is less conclusive.
For mild to moderate depression, some studies suggest St. John's Wort may be as effective as certain prescription antidepressants. However, results can vary, and it is not generally recommended as a substitute for standard care for severe depression.
Clinical studies indicate that St. John's Wort can be effective for relieving symptoms of mild depression. Its efficacy in this context has been compared to that of some conventional antidepressants. However, individual responses may vary.
schedule Dosage, timing & forms
Common dosages of St. John's Wort extract often range from 300 mg to 900 mg per day. These dosages typically provide standardized amounts of active compounds like hypericin or hyperforin. It's important to check the product label for specific recommendations.
The effects of St. John's Wort are generally not immediate and may take several weeks to become noticeable. Individuals typically report feeling benefits after two to four weeks of consistent daily use. It's important to continue taking it as directed for the recommended duration.
The effects of St. John's Wort are typically not immediate and may take several weeks to become noticeable. Individuals often report initial changes within 2 to 4 weeks, with more pronounced benefits potentially appearing after 4 to 6 weeks of consistent use. This gradual onset is common for many herbal supplements.
Common dosages for St. John's Wort extracts, often standardized to hypericin or hyperforin, typically range from 300 mg to 900 mg per day. These doses are usually divided into two or three administrations throughout the day. The specific dosage can vary based on the extract's standardization and the product's concentration.
St. John's Wort is typically taken two to three times per day. Dividing the daily dose helps maintain consistent levels of its active compounds in the body. Always follow the specific instructions provided on the supplement's label or by a qualified healthcare professional.
health_and_safety Safety & interactions
No, St. John's Wort should not be taken with antidepressant medications, especially selective serotonin reuptake inhibitors (SSRIs). Combining them can lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high fever. Always consult a healthcare professional before combining St. John's Wort with any prescription drugs.
Yes, St. John's Wort can interact significantly with many antidepressant medications. This interaction may lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high blood pressure. It is crucial to consult a healthcare professional before combining St. John's Wort with any antidepressant.
St. John's Wort can interact significantly with many medications, reducing their effectiveness or increasing side effects. Common side effects may include photosensitivity, upset stomach, fatigue, and restlessness. It is important to discuss its use with a healthcare provider.
Yes, St. John's Wort significantly interacts with medications used for HIV/AIDS (e.g., protease inhibitors, NNRTIs) and immunosuppressants used after organ transplantation (e.g., cyclosporine). It can dramatically reduce the levels and effectiveness of these critical drugs. Such combinations are generally contraindicated and should be strictly avoided.
Yes, St. John's Wort is known to reduce the effectiveness of hormonal contraceptives, including birth control pills. This interaction can potentially lead to unintended pregnancy. It is recommended to use an alternative or additional method of contraception while taking St. John's Wort.
Ingredients
| Ingredient | Amount per serving |
|---|---|
St. John's Wort | 450 mg |
Categories
St. John's Wort 65.0
Offering a good dosage of whole herb St. John's Wort from a reputable brand at a competitive price for a large quantity, it presents good value for consistent use within the St. John's Wort category, despite lacking standardization.
Goals
Mood Support 68.0
From a reputable brand and at a reasonable dosage for a whole herb, it offers consistent use for mood support, although not as potent or reliable as standardized extracts.
Stress Relief 65.0
The product's good value allows for consistent daily use, which is important for gradual stress relief, even if it's an unstandardized whole herb.
Sleep Support 60.0
Its indirect benefits on sleep are tied to its effects on mood and stress, and as an unstandardized whole herb, its direct impact on sleep quality might be limited.
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