Product Image

VO2 Max Performance Fat Burner

Irwin Naturals
4.3
★ ★ ★ ★ ★
(210 ratings)
Ashwagandha 300 mg
Green Tea 270 mg
Product Image
Score71
A capable daytime energy formula with KSM-66, moderate caffeine, EGCG, and active B12. It suits focus and fitness better than sleep, and its stimulant and ashwagandha precautions matter.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
Energy
Anti-Aging
Cognitive Support
Fitness
Productivity Boost
Muscle Gain
Anti-Inflammatory Support
Brain Health

Score 71

A capable daytime energy formula with KSM-66, moderate caffeine, EGCG, and active B12. It suits focus and fitness better than sleep, and its stimulant and ashwagandha precautions matter.
How scoring works
$28.99($0.96 per serving)
Pure Formulas
$ 29.99
Amazon
$ 28.99
iHerb
$ 29.99
Vitacost
$ 29.99
Report prices

Analysis

The softgels provide 300 mg KSM-66 ashwagandha, 75 mg caffeine, green tea supplying about 135 mg EGCG, and 50 mcg methylcobalamin. Those ingredients align most strongly with daytime energy, focus, stress adaptation, and exercise support.

MCT oil, flaxseed oil, maca, schisandra, and B vitamins broaden the formula, though several are supportive rather than decisive. Caffeine works against sleep and may also undermine calm-focused use despite the ashwagandha.

Two softgels are convenient, but this is not a direct muscle-building, skin, or anti-aging foundation. Stimulant timing and ashwagandha suitability matter more than the long marketing-style goal list.

Who is it for
  • Healthy adults seeking moderate daytime stimulation
  • Active users who value KSM-66 ashwagandha
  • People who tolerate 75 mg caffeine
Best for
  • Daytime energy and focus
  • Stress-adapted exercise support
  • Moderate pre-workout stimulation

Pros

  • Provides 300 mg KSM-66
  • Clearly states 75 mg caffeine
  • Includes green-tea EGCG and methylcobalamin

Cons

  • Poor fit for sleep support
  • Many secondary ingredients add complexity
  • Does not provide a direct muscle-building foundation

Warnings

  • Count the 75 mg caffeine with all other daily sources; it may cause anxiety, palpitations, or sleep disruption, especially when taken late.
  • Ashwagandha warrants individualized guidance during pregnancy and for thyroid, liver, or interacting-medication concerns.

Nutrient quality

70 High impact

Standardized green tea and ashwagandha support energy, but oils and lightly dosed botanicals broaden the formula. Several amounts are useful but not consistently strong.

Ingredient transparency

85 Highest impact

Active ingredients have stated amounts without a proprietary blend. Several extracts also identify useful forms or standards.

Customer satisfaction

71 High impact

The aggregate rating is mixed and is supported by limited review volume. No specific comments are supplied, so repeated complaints and purpose alignment cannot be confirmed directly.

Value for money

55 Moderate impact

Value is limited for the effective doses and ingredient forms. Lightly dosed additions or premium pricing weaken competitiveness.

Report analysis

Goals

Energy
Energy
Impact
Highest effect
A- Goal FitA- Strength of SupportA- CoverageB+ Formula Quality
Vitamin B5 · 15 mgVitamin B12 · 50 mcgCaffeine · 75 mg

VO2 Max Performance Fat Burner is strongly aligned with the Energy goal because its highlighted actives include Caffeine at 75 mg, methylcobalamin at 50 mcg, KSM-66 at 300 mg, MCT oil at 500 mg, and green tea extract; evidence quality for the formula as a whole is good.

Customer feedback averages 4.27 out of 5 across 210 reviews; ashwagandha warrants caution during pregnancy and with thyroid, liver, or interacting-medication concerns, and the 75 mg caffeine serving should be counted alongside other daily caffeine sources.

Study evidence
Ashwagandha Supportive 9 studies
Caffeine Supportive 68 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B+ Goal FitA- Strength of SupportB- CoverageB Formula Quality
Folate · 340 mcg DFEVitamin B12 · 50 mcgGreen Tea · 270 mg

VO2 Max Performance Fat Burner aligns with Anti-Aging mainly through Ashwagandha, while the supplied collection analyses average 79.7 and supplied customer feedback is 4.27 from 210 reviews.

Its strongest feature is form and disclosure quality, while coverage remains intentionally narrow; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha No effect 1 study
Cognitive Support
Cognitive Support
Impact
Highest effect
B+ Goal FitA- Strength of SupportB- CoverageB Formula Quality
Vitamin B6 · 5 mgFolate · 340 mcg DFEVitamin B12 · 50 mcgGreen Tea · 270 mgAshwagandha · 300 mg

VO2 Max Performance Fat Burner aligns with Cognitive Support mainly through Ashwagandha, while the supplied collection analyses average 79.7 and supplied customer feedback is 4.27 from 210 reviews.

Its strongest feature is form and disclosure quality, while coverage remains intentionally narrow; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha Supportive 17 studies
Fitness
Fitness
Impact
High effect
B+ Goal FitA- Strength of SupportB CoverageC+ Formula Quality
Ashwagandha · 300 mgCaffeine · 75 mg

VO2 Max Performance Fat Burner uses a branded, marker-standardized ashwagandha extract and may support stress adaptation, recovery, and selected performance outcomes, although its fitness role is less direct than core ergogenic ingredients.

The disclosed dose and formula structure support a strong contribution, while evidence and pathway coverage remain the main constraints.

Study evidence
Ashwagandha Supportive 23 studies
Caffeine Supportive 255 studies
Productivity Boost
Productivity Boost
Impact
High effect
B Goal FitA- Strength of SupportB CoverageC+ Formula Quality
Vitamin B12 · 50 mcgVitamin B12 · 50 mcgVitamin B6 · 5 mgCaffeine · 75 mg

VO2 Max Performance Fat Burner has a direct fit for productivity through its disclosed focus, energy, or stress-resilience ingredients.

Dose quality and formula structure support a strong contribution, with evidence and unnecessary complexity setting the main limits.

Study evidence
Ashwagandha Supportive 6 studies
Caffeine Supportive 108 studies
Muscle Gain
Muscle Gain
Impact
High effect
B- Goal FitA- Strength of SupportC+ CoverageC Formula Quality
Caffeine · 75 mg

VO2 Max Performance Fat Burner may support stress adaptation and selected strength outcomes through ashwagandha, but it is an indirect muscle-gain option without a protein or core ergogenic foundation.

The disclosed dose and formula structure support a strong adaptogenic contribution, while direct hypertrophy relevance and pathway breadth remain the main constraints.

Study evidence
Ashwagandha Supportive 10 studies
Caffeine Supportive 31 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Fat
1 Gram(s)
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Niacin (Niacinamide)
 10 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 5 mg
Folate
340 mcg DFE
Vitamin B12 (Methylcobalamin)
 50 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 15 mg
Flaxseed Oil
850 mg
Medium Chain Triglyceride Oil
500 mg
KSM-66 Ashwagandha extract (Withanolides)
 300 mg
Green Tea extract (EGCG, Polyphenols)
 270 mg
Maca powder
250 mg
Schisandra extract
150 mg
Caffeine (Coffee)
 75 mg
BioPerine Complex
3 mg
Women Women 18–50
Report overview
Ashwagandha (Withanolides) · 300 mg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value
+3

Irwin Naturals VO2 Max provides 300 mg of KSM-66 ashwagandha root extract with BioPerine and has 210 reviews averaging 4.27. Its form, dose, delivery, transparency, and $0.96 per-serving price were evaluated directly against the collection rubric.

View ingredientView products
Green Tea (EGCG, Polyphenols) · 270 mg OverallScore69
A- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Irwin Naturals VO2 Max Performance Fat Burner uses 270 mg of green tea extract standardized to 50% EGCG, providing 135 mg EGCG, with 210 reviews averaging 4.27. BioPerine and exact 75 mg caffeine disclosure are useful, but the EGCG dose and approximately $1.42 cost per 200 mg score only moderately.

View ingredientView products
Loading alternative details
87 Performance

Ashwagandha KSM-66 600 mg

NutraBio
<p>A single 600 mg KSM-66 ashwagandha extract gives a more concentrated and clearly identified ashwagandha option than the original blend. It is not a direct fat-burner replacement because it contains no green tea or caffeine, but it is better aligned with stress and recovery support.</p>
86 Performance

Anxiety & Stress Relief

Nature's Bounty
<p>The combination of 600 mg ashwagandha extract and 200 mg L-theanine is more focused on calm attention and stress support than the original stimulant-heavy formula. Green tea and caffeine are absent, reducing overlap with the original energy emphasis.</p>
84 Performance

EGCg Green Tea Extract 400 mg

NOW
<p>The 400 mg green tea extract identifies both EGCG and total catechins and also includes decaffeinated green tea. Compared with the original, it gives green tea a clearer, more focused role but does not retain ashwagandha or the supporting oils and vitamins.</p>
87 Budget

Standardized Extract Ashwagandha 450 mg

NOW
<p>The much lower cost per serving provides 450 mg of ashwagandha extract standardized to total withanolides. It removes caffeine, green tea, oils, and B vitamins, so it is a simpler choice when ashwagandha is the main priority rather than stimulant support.</p>
86 Budget

Optimized Ashwagandha

Life Extension
<p>A lower cost per serving delivers a named Sensoril ashwagandha extract with disclosed withanolide-related forms. The streamlined formula lacks the original product's caffeine and green tea, which may suit someone seeking stress support without the broader stimulant blend.</p>
84 Budget

EGCg Green Tea Extract

Protocol For Life Balance
<p>The cost per serving is markedly lower, while 400 mg green tea extract lists both catechins and EGCG and includes a decaffeinated component. It focuses on the original product's green tea element but omits ashwagandha and the other energy-oriented ingredients.</p>
87 Value

Ultimate Ashwagandha 250 mg KSM-66

Swanson
<p>KSM-66 ashwagandha is supplied in a simple 250 mg serving at a much lower cost per serving. It offers strong value for the original product's ashwagandha component, though it does not reproduce the caffeine and green tea side of the formula.</p>
86 Value

Ashwagandha

Jarrow Formulas
<p>A straightforward 300 mg ashwagandha extract costs far less per serving and avoids paying for the original product's broad mix of oils and botanicals. The trade-off is limited extract standardization and no green tea or stimulant support in the supplied formula.</p>
79 Value

Decaffeinated Mega Green Tea Extract

Life Extension
<p>The decaffeinated green tea extract supplies a high listed amount with EGCG and polyphenols at a lower cost per serving. It offers a clearer value proposition for green tea exposure than the original, but does not include ashwagandha or caffeine-driven energy support.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
    Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
    Randomized trialEnergy forAshwagandha
  2. An Examination into the Anti-stress and Anti-fatigue Effects of an Ashwagandha Extract (Ashwa.30™) in Stressed Adults: A Randomised, Double-Blind, Placebo-controlled Trial.
    Lopresti AL; Smith SJ; Bethapudi B; R AA; Mundkinajeddu D; D'Souza P; Lakshmikanthan S · Advances in therapy · 2026
    Randomized trial60 participantsEnergy forAshwagandha
  3. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsEnergy Mental Focus Brain Health Cognitive Support forAshwagandha
  4. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males.
    Lopresti AL; Drummond PD; Smith SJ · American journal of men's health · 2020
    Randomized trial57 participantsEnergy Anti-Aging forAshwagandha
  5. Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
    Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
    Randomized trial80 participantsFitness Muscle Gain forAshwagandha
  6. Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial.
    Ziegenfuss TN; Kedia AW; Sandrock JE; Raub BJ; Kerksick CM; Lopez HL · Nutrients · 2019
    Randomized trial38 participantsFitness forAshwagandha
  7. Effects of an 8-week high intensity interval training (HIIT) and ashwagandha supplementation on aerobic capacity, muscle oxygenation and haematological parameters in healthy men.
    Ewa J; Klusiewicz A; Rębiś K; Długołęcka B; Charmas M; Cieśliński I · Biology of sport · 2025
    Randomized trial33 participantsFitness forAshwagandha
  8. Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
    Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
    Meta-analysis1,249 participants20 studies pooledFitness Mental Focus Muscle Gain forAshwagandha
  9. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.
    Albalawi AA · Nutrition and health · 2025
    Meta-analysis488 participants13 studies pooledStress Relief forAshwagandha
  10. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  11. The Impact of Ashwagandha on Stress, Sleep Quality, and Food Cravings in College Students: Quantitative Analysis of a Double-Blind Randomized Control Trial.
    O'Connor J; Lindsay K; Baker C; Kirby J; Hutchins A; Harris M · Journal of medicinal food · 2022
    Randomized trial60 participantsStress Relief forAshwagandha
  12. The effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials.
    Kim S; Park TH; Kim WI; Park S; Kim JH; Cho MK · Phytotherapy research : PTR · 2021
    Meta-analysis247 participants5 studies pooledAnti-Inflammatory Support forGreen Tea
  13. Green Tea Catechin Association with Ultraviolet Radiation-Induced Erythema: A Systematic Review and Meta-Analysis.
    Kapoor MP; Sugita M; Fukuzawa Y; Timm D; Ozeki M; Okubo T · Molecules (Basel, Switzerland) · 2021
    Meta-analysis100 participants6 studies pooledAnti-Inflammatory Support Skin Health forGreen Tea
  14. Efficacy of (-)-epigallocatechin gallate delivered by a new-type scaler tip during scaling and root planing on chronic periodontitis: a split-mouth, randomized clinical trial.
    Wang Y; Zeng J; Yuan Q; Luan Q · BMC oral health · 2021
    Randomized trial20 participantsAnti-Inflammatory Support forGreen Tea
  15. Camellia Sinensis Mouthwashes in Oral Care: a Systematic Review.
    Tafazoli A; Tafazoli Moghadam E · Journal of dentistry (Shiraz, Iran) · 2020
    Systematic review69 studies pooledAnti-Inflammatory Support forGreen Tea
  16. Skin photoprotection by green tea: antioxidant and immunomodulatory effects.
    Katiyar SK · Current drug targets. Immune, endocrine and metabolic disorders · 2004
    Narrative reviewAnti-Inflammatory Support forGreen Tea
  17. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  18. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  19. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  20. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Stress Relief forAshwagandha
  21. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  22. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  23. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsEnergy Mood Support forAshwagandha
  24. Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
    Vittal M; Vinciguerra M · Biogerontology · 2025
    Narrative reviewEnergy forAshwagandha
  25. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsEnergy Productivity Boost forAshwagandha
  26. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  27. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  28. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  29. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  30. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  31. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
    Choudhary B; Shetty A; Langade DG · Ayu · 2016
    Randomized trial50 participantsFitness forAshwagandha
  32. Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists.
    Shenoy S; Chaskar U; Sandhu JS; Paadhi MM · Journal of Ayurveda and integrative medicine · 2013
    Randomized trial40 participantsFitness forAshwagandha
  33. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  34. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  35. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  36. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  37. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  38. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  39. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  40. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  41. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  42. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  43. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  44. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  45. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  46. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  47. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  48. Ashwagandha Root Extract Stabilises Physiological Stress Responses in Male and Female Team Sports Athletes During Pre-Season Training.
    Coope OC; Otaegui E; Suárez M; Levington A; Abad-Sangrà M; Lloyd B; Spurr TJ; Roman-Viñas B · Nutrients · 2026
    Randomized trial56 participantsMuscle Gain forAshwagandha
  49. Evaluation of Withania somnifera (L.) Dunal (Ashwagandha) on Physical Performance, Biomarkers of Inflammation, and Muscle Status in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Study.
    Raut A; Tripathi R; Marathe PA; Uchil DA; Agashe S; Rege N; Vaidya AB · Cureus · 2024
    Randomized trialMuscle Gain forAshwagandha
  50. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
    Wankhede S; Langade D; Joshi K; Sinha SR; Bhattacharyya S · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial57 participantsMuscle Gain forAshwagandha
  51. Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.
    Wu W; Chen Z; Zhou H; Wang L; Li X; Lv Y; Sun T; Yu L · Nutrients · 2024
    Meta-analysis14 studies pooledMuscle Gain forCaffeine
  52. Acute caffeine intake improves muscular strength, power, and endurance performance, reversing the time-of-day effect regardless of muscle activation level in resistance-trained males: a randomized controlled trial.
    Montalvo-Alonso JJ; Del Val-Manzano M; Cerezo-Telléz E; Ferragut C; Valadés D; Rodríguez-Falces J; Pérez-López A · European journal of applied physiology · 2025
    Randomized trial13 participantsMuscle Gain forCaffeine
  53. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses.
    Grgic J; Grgic I; Pickering C; Schoenfeld BJ; Bishop DJ; Pedisic Z · British journal of sports medicine · 2020
    Systematic review21 studies pooledMuscle Gain forCaffeine
  54. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis.
    Grgic J; Trexler ET; Lazinica B; Pedisic Z · Journal of the International Society of Sports Nutrition · 2018
    Meta-analysis20 studies pooledMuscle Gain forCaffeine
  55. Caffeine increases strength and power performance in resistance-trained females during early follicular phase.
    Norum M; Risvang LC; Bjørnsen T; Dimitriou L; Rønning PO; Bjørgen M; Raastad T · Scandinavian journal of medicine & science in sports · 2021
    Randomized trial15 participantsMuscle Gain forCaffeine
  56. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledProductivity Boost forAshwagandha
  57. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost forAshwagandha
  58. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  59. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  60. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  61. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  62. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
  63. Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  64. Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial.
    Stockfleth E; Beti H; Orasan R; Grigorian F; Mescheder A; Tawfik H; Thielert C · The British journal of dermatology · 2008
    Randomized trial503 participantsSkin Health forGreen Tea
  65. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis.
    Tzellos TG; Sardeli C; Lallas A; Papazisis G; Chourdakis M; Kouvelas D · Journal of the European Academy of Dermatology and Venereology : JEADV · 2011
    Meta-analysis1,247 participants3 studies pooledSkin Health forGreen Tea
  66. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women.
    Heinrich U; Moore CE; De Spirt S; Tronnier H; Stahl W · The Journal of nutrition · 2011
    Randomized trial60 participantsSkin Health forGreen Tea
  67. Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial.
    Zhao H; Zhu W; Zhao X; Li X; Zhou Z; Zheng M; Meng X; Kong L; Zhang S; He D; Xing L; Yu J · JAMA dermatology · 2022
    Randomized trial180 participantsSkin Health forGreen Tea
  68. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  69. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha