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Heart Collagen + Resveratrol

youtheory
4.6
★ ★ ★ ★ ★
(147 ratings)
Vitamin K 180 mcg
Resveratrol 200 mg
Collagen 2500 mg
Product Image
Score80
Meaningful trans-resveratrol and MK-7 amounts give this formula a clear cardiovascular purpose, with collagen adding structural support. A high tablet burden, incomplete collagen disclosure, and medication interactions are the main trade-offs.
How scoring works
Quantity:150 Tablet(s) • (25 servings)
Goals:
Anti-Aging
Bone Health
Cardiovascular Support
Heart Health
Anti-Inflammatory Support
Skin Health
General Health

Score 80

Meaningful trans-resveratrol and MK-7 amounts give this formula a clear cardiovascular purpose, with collagen adding structural support. A high tablet burden, incomplete collagen disclosure, and medication interactions are the main trade-offs.
How scoring works
$19.99($0.79 per serving)
iHerb
$ 19.99
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Analysis

The formula pairs 200 mg of pure trans-resveratrol with 180 mcg of vitamin K2 as MK-7, creating a clear cardiovascular and antioxidant focus. A 2.5-gram hydrolyzed collagen serving adds connective-tissue support and reaches a useful beauty-oriented amount.

Ingredient forms and amounts are easy to assess, particularly for resveratrol and K2. Collagen quality is less transparent because its animal source, type, amino acid profile, and any standardization are not provided, and the dry tablet format offers no stated absorption support for the fat-soluble K2.

Six tablets per serving may be inconvenient for daily use, but the actives are more focused and transparent than many broad blends. The strongest fit is for adults seeking targeted cardiovascular support who can safely use vitamin K2 and resveratrol alongside their medications.

Who is it for
  • Adults seeking combined resveratrol and vitamin K2 support
  • People interested in cardiovascular and connective-tissue support
  • Users comfortable taking six tablets per serving
Best for
  • Cardiovascular support
  • Trans-resveratrol supplementation
  • A combined collagen and K2 routine

Pros

  • Uses clearly identified pure trans-resveratrol
  • Provides vitamin K2 in the MK-7 form
  • Discloses meaningful amounts for all three actives
  • Keeps the formula focused without an opaque proprietary blend

Cons

  • Requires six tablets per serving
  • Collagen source and type are not stated
  • No advanced resveratrol delivery feature is identified
  • No guidance is supplied about taking K2 with a fat-containing meal

Warnings

  • Vitamin K2 can counter vitamin K antagonist medicines such as warfarin; use requires clinician-guided consistency.
  • Resveratrol may add to bleeding risk when combined with anticoagulant or antiplatelet medicines.
  • The collagen animal source is undisclosed, so people with dietary or source-specific restrictions cannot verify suitability.

Nutrient quality

89 Highest impact

Pure trans-resveratrol, MK-7, and hydrolyzed collagen are credible forms supplied at useful amounts. Collagen lacks source and type details, and its role is less direct in a heart-focused formula.

Ingredient transparency

84 Highest impact

Every active ingredient has a specific amount and no proprietary blend obscures the formula. Missing collagen source details, non-active ingredients, and fuller use directions leave avoidable gaps.

Customer satisfaction

67 High impact

The average rating is strong and the review count gives it reasonable support. No review excerpts or complaint patterns are supplied to assess recurring problems or purpose-specific experiences.

Value for money

76 High impact

Three purposeful actives in useful forms give the formula reasonable substance. The six-tablet serving and incomplete collagen sourcing limit convenience and keep value from standing out.

Report analysis

Goals

Anti-Aging
Anti-Aging
Impact
Highest effect
B+ Goal FitA- Strength of SupportA- CoverageA+ Formula Quality
Vitamin K · 180 mcgCollagen · 2500 mg

The formula combines structural support, antioxidant signaling, and healthy calcium handling. It provides 2.5 g of collagen, 200 mg of pure trans-resveratrol, and 180 mcg of MK-7 vitamin K2 for the stated purpose.

Collagen is below stronger daily skin amounts and long-term resveratrol outcomes remain uncertain. Vitamin K2 can reduce warfarin’s effect, while resveratrol may add to bleeding tendency with anticoagulant medicines.

Study evidence
Collagen Supportive 33 studies
Resveratrol No effect 7 studies
Vitamin K Supportive 27 studies
Bone Health
Bone Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageA- Formula Quality
Vitamin K · 180 mcgCollagen · 2500 mg

Collagen and MK-7 address the bone protein matrix and mineral placement, while resveratrol adds antioxidant support. The combination is relevant, although evidence for resveratrol as a bone active is less established.

The collagen amount is meaningful but below common higher-dose structural servings, while MK-7 is well supplied. Vitamin K2 can oppose warfarin and other vitamin K antagonist anticoagulants, making this a specific medication interaction.

Study evidence
Collagen Supportive 16 studies
Vitamin K Supportive 78 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B- Goal FitA+ Strength of SupportB- CoverageB+ Formula Quality
Vitamin K · 180 mcg

Trans-resveratrol and MK-7 vitamin K2 support endothelial signaling, antioxidant defense, and calcium handling. Collagen contributes structural protein but has less direct cardiovascular relevance.

The resveratrol and K2 amounts are substantial and their forms are clearly identified. K2 opposes warfarin, while resveratrol may add to bleeding tendency with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 73 studies
Vitamin K Supportive 40 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportB CoverageB- Formula Quality
Vitamin K · 180 mcg

MK-7 and trans-resveratrol support arterial calcium handling and endothelial antioxidant pathways. The evidence is stronger for K2 biology than for hard cardiovascular outcomes from resveratrol.

Both heart-relevant actives are meaningfully dosed and clearly identified, while collagen is mainly structural support outside this goal. MK-7 can counter vitamin K antagonist medicines such as warfarin, making this formula unsuitable with that drug class unless specifically managed.

Study evidence
Resveratrol Supportive 66 studies
Vitamin K Mixed 62 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitB Strength of SupportB- CoverageA- Formula Quality
Collagen · 2500 mg

Trans-resveratrol provides antioxidant and cellular-signaling support, while hydrolyzed collagen may support connective tissue. Human inflammatory evidence is moderate and more relevant to markers than broad symptom relief.

Both main actives are supplied at meaningful supportive amounts. The six-tablet serving and lack of advanced resveratrol delivery reduce practicality.

Study evidence
Collagen Supportive 5 studies
Resveratrol Supportive 34 studies
Skin Health
Skin Health
Impact
High effect
B+ Goal FitB- Strength of SupportB CoverageB Formula Quality
Collagen · 2500 mgResveratrol · 200 mg

Hydrolyzed collagen and trans-resveratrol combine structural and antioxidant skin support. Hydrolyzed peptides provide a skin-relevant form with human support for hydration and elasticity.

Collagen reaches the lower useful skin range and resveratrol is supplied at a supportive amount. Vitamin K2 can counteract warfarin and other vitamin K antagonist anticoagulants.

Study evidence
Collagen Supportive 62 studies
Resveratrol Supportive 7 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7)
 180 mcg
hydrolyzed Collagen
2500 mg
Resveratrol (Pure Trans-Resveratrol)
 200 mg
Adults 18–50 Women
Report overview
Vitamin K (Menaquinone-7) · 180 mcg OverallScore71
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

MK-7 provides the preferred vitamin K form, though its generic source is not branded or all-trans verified. The dry tablet lacks stated fat-meal guidance, limiting absorption support. The MK-7 amount is well aligned with the clinical target range; the high serving cost and generic source limit value.

View ingredientView products
Resveratrol (Pure Trans-Resveratrol) · 200 mg OverallScore62
C+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyD- Value

Pure trans-resveratrol is clearly identified at a supportive 200 mg dose. Six pressed tablets are required and provide no advanced delivery support, though the non-knotweed presentation avoids the specific emodin concern. Cost efficiency is moderate, with the substantial collagen dose supplying separate value.

View ingredientView products
Collagen · 2500 mg OverallScore40
D+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Hydrolyzed collagen supports absorption, and the 2,500 mg amount reaches the skin-focused dose range. Animal origin, collagen type, branded standardization, protein matching, and an amino acid profile are not disclosed. The cost per gram sits just inside the weak-value tier.

View ingredientView products
Loading alternative details
78 Performance

Bone Collagen + D3 & K2

youtheory
Vitamin D3, calcium, magnesium, MK-7 vitamin K2, and collagen give broader bone-focused coverage than the original three-ingredient formula. The trade-off is the loss of trans-resveratrol and its associated cardiovascular and antioxidant support.
70 Performance

Hair Skin & Nails

Bluebonnet Beautiful Ally
Type I and III collagen, MSM, keratin, glutathione, CoQ10, and biotin create broader hair, skin, and nail support. It is less suitable for the original heart and bone goals because it lacks vitamin K2 and provides far less trans-resveratrol.
73 Performance

Collagen Beauty

Irwin Naturals
Branded type I and III collagen peptides plus vitamin C, biotin, oils, and plant extracts broaden skin-focused support. The collagen amount matches the original, but the much smaller resveratrol amount and absent vitamin K2 weaken heart and bone alignment.
78 Budget

Bone Collagen + D3 & K2

youtheory
The lower serving cost preserves the same MK-7 vitamin K2 and collagen amounts while adding vitamin D3, calcium, and magnesium. It gives stronger bone-focused coverage, but it omits the original product's resveratrol.
70 Budget

Hair Skin & Nails

Bluebonnet Beautiful Ally
The listed serving cost is slightly higher rather than lower, because the eligible candidate pool does not contain three cheaper choices. It still adds type I and III collagen, MSM, keratin, glutathione, and CoQ10, though its resveratrol amount is much smaller and it lacks vitamin K2.
79 Budget

Collagen Bone Complete

Solaray
The listed serving cost is higher, so it is not a true cheaper substitute; fewer than three eligible lower-cost candidates were provided. It retains vitamin K2 and adds vitamin D3, calcium, magnesium, and a disclosed marine collagen source, but the collagen serving is much smaller.
78 Value

Bone Collagen + D3 & K2

youtheory
The lower serving cost and matching amounts of collagen and MK-7 vitamin K2 provide strong value for bone support. Added vitamin D3, calcium, and magnesium broaden the formula, although resveratrol is absent.
70 Value

Hair Skin & Nails

Bluebonnet Beautiful Ally
The serving cost is close to the original while the formula covers collagen, keratin, MSM, biotin, glutathione, and CoQ10. Its beauty-focused breadth may offer value for hair, skin, and nails, but it gives up meaningful vitamin K2 and resveratrol support.
79 Value

Collagen Bone Complete

Solaray
Vitamin D3, calcium, magnesium, vitamin K2, and source-identified marine collagen provide coherent bone support in one formula. Its serving cost is somewhat higher and collagen is lightly dosed, so the value depends on wanting the added minerals rather than collagen potency.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study.
    Lee M; Kim E; Ahn H; Son S; Lee H · Food & function · 2023
    Randomized trial100 participantsAnti-Aging Skin Health forCollagen
  2. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis.
    de Miranda RB; Weimer P; Rossi RC · International journal of dermatology · 2021
    Meta-analysis1,125 participants19 studies pooledAnti-Aging Skin Health forCollagen
  3. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study.
    Proksch E; Segger D; Degwert J; Schunck M; Zague V; Oesser S · Skin pharmacology and physiology · 2014
    Randomized trial69 participantsAnti-Aging forCollagen
  4. Skin Anti-Aging and Moisturizing Effects of Low-Molecular-Weight Collagen Peptide Supplementation in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Lee E; Ahn DK; Kim JH; Lee S; Kim HJ; Lee HK; Shin JH · Journal of microbiology and biotechnology · 2025
    Randomized trial70 participantsAnti-Aging forCollagen
  5. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis.
    Proksch E; Schunck M; Zague V; Segger D; Degwert J; Oesser S · Skin pharmacology and physiology · 2014
    Randomized trial114 participantsAnti-Aging forCollagen
  6. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
    Witte AV; Kerti L; Margulies DS; Flöel A · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Randomized trial46 participantsAnti-Aging forResveratrol
  7. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsAnti-Aging forResveratrol
  8. Resveratrol levels and all-cause mortality in older community-dwelling adults.
    Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C · JAMA internal medicine · 2014
    Cohort study783 participantsAnti-Aging forResveratrol
  9. Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
    Mansouri F; Feliziani G; Bordoni L; Gabbianelli R · Journal of the Academy of Nutrition and Dietetics · 2025
    Meta-analysis11 studies pooledAnti-Aging forResveratrol
  10. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.
    Rao A; Briskey D; Roche G; Tremblay A; Da Silva Pinto M; Tompkins TA · Frontiers in aging · 2026
    Randomized trial134 participantsAnti-Aging Skin Health forResveratrol
  11. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  12. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  13. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  14. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  15. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  16. Undenatured type II collagen for knee osteoarthritis.
    Gupta A; Maffulli N · Annals of medicine · 2025
    Systematic review12 studies pooledAnti-Inflammatory Support forCollagen
  17. Anti-inflammatory effect of collagen tripeptide in atopic dermatitis.
    Hakuta A; Yamaguchi Y; Okawa T; Yamamoto S; Sakai Y; Aihara M · Journal of dermatological science · 2018
    Randomized trial17 participantsAnti-Inflammatory Support forCollagen
  18. [Points of undenatured type II collagen application in musculoskeletal pain syndromes treatment].
    Shavlovskaya OA; Gromova OA; Torshin IY · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2022
    Narrative reviewAnti-Inflammatory Support forCollagen
  19. Ultrasound Guided Injection of Collagen for Elbow Lateral Epicondylitis - A Pilot Study.
    Porta F; Filippucci E; Barni X; Dinescu SC; Vreju FA · Current health sciences journal · 2026
    Single-arm trial13 participantsAnti-Inflammatory Support forCollagen
  20. Effects of porcine-derived collagen hydrolysates on 24 h blood pressure profiles, markers for endothelial dysfunction and low-grade inflammation and the retinal vasculature in adults with overweight/obesity: a randomized, controlled trial.
    Chavez-Alfaro MA; Mensink RP; Joris PJ; Plat J · Food & function · 2025
    Randomized trial56 participantsAnti-Inflammatory Support forCollagen
  21. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  22. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  23. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  24. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsAnti-Inflammatory Support forResveratrol
  25. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  26. Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides on Volumetric and Areal Bone Mineral Density, Bone Geometry and Bone Turnover in Postmenopausal Women With Osteopenia.
    Lampropoulou-Adamidou K; Karlafti E; Argyrou C; Makris K; Trovas G; Dontas IA; Tournis S; Triantafyllopoulos IK · Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry · 2022
    Randomized trial51 participantsBone Health forCollagen
  27. Bone turnover and bone collagen maturation in osteoporosis: effects of antiresorptive therapies.
    Byrjalsen I; Leeming DJ; Qvist P; Christiansen C; Karsdal MA · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2008
    Randomized trialBone Health forCollagen
  28. A calcium-collagen chelate dietary supplement attenuates bone loss in postmenopausal women with osteopenia: a randomized controlled trial.
    Elam ML; Johnson SA; Hooshmand S; Feresin RG; Payton ME; Gu J; Arjmandi BH · Journal of medicinal food · 2015
    Randomized trial39 participantsBone Health forCollagen
  29. Assessment of Osteoporosis in Lumbar Spine: In Vivo Quantitative MR Imaging of Collagen Bound Water in Trabecular Bone.
    Liu J; Liao JW; Li W; Chen XJ; Feng JX; Yao L; Huang PH; Su ZH; Lu H; Liao YT; Li SL; Ma YJ · Frontiers in endocrinology · 2022
    Methods validation study189 participantsBone Health forCollagen
  30. Effect of calcium and vitamin D supplementation with and without collagen peptides on bone turnover in postmenopausal women with osteopenia.
    Argyrou C; Karlafti E; Lampropoulou-Adamidou K; Tournis S; Makris K; Trovas G; Dontas I; Triantafyllopoulos IK · Journal of musculoskeletal & neuronal interactions · 2021
    Randomized trial51 participantsBone Health forCollagen
  31. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  32. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  33. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  34. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  35. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  36. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; García-Almagro FJ; Avilés-Plaza F; Parra S; Yáñez-Gascón MJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · Molecular nutrition & food research · 2012
    Randomized trial75 participantsCardiovascular Support forResveratrol
  37. Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.
    Ahmadi P; Akbarzadeh S; Alizadeh M; Mohammadi N; Mahmoodi M; Amini A; Netticadan T; Rezaei M; Movahed A · Molecular and cellular biochemistry · 2025
    Randomized trial60 participantsCardiovascular Support forResveratrol
  38. Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases.
    Shen CY; Li CP; Yu JT; Ho YJ; Tsai RY · In vivo (Athens, Greece) · 2026
    Meta-analysis2,551 participants40 studies pooledCardiovascular Support forResveratrol
  39. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
    Wong RH; Berry NM; Coates AM; Buckley JD; Bryan J; Kunz I; Howe PR · Journal of hypertension · 2014
    Randomized trial28 participantsCardiovascular Support Heart Health forResveratrol
  40. Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind, placebo-controlled trial.
    Simental-Mendía LE; Guerrero-Romero F · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Randomized trial71 participantsCardiovascular Support forResveratrol
  41. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  42. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  43. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  44. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  45. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  46. A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis.
    Kumar S; Sugihara F; Suzuki K; Inoue N; Venkateswarathirukumara S · Journal of the science of food and agriculture · 2015
    Randomized trialGeneral Health forCollagen
  47. Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double-blind, placebo-controlled trial.
    Luo C; Su W; Song Y; Srivastava S · Journal of experimental orthopaedics · 2023
    Randomized trial101 participantsGeneral Health forCollagen
  48. Healing Process, Pain, and Health-Related Quality of Life in Patients with Venous Leg Ulcers Treated with Fish Collagen Gel: A 12-Week Randomized Single-Center Study.
    Mościcka P; Cwajda-Białasik J; Szewczyk MT; Jawień A · International journal of environmental research and public health · 2022
    Randomized trial100 participantsGeneral Health forCollagen
  49. Efficacy and Safety of Dietary Undenatured Type II Collagen on Joint and Motor Function in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study.
    Shiojima Y; Takahashi M; Takahashi R; Maruyama K; Moriyama H; Bagchi D; Bagchi M; Akanuma M · Journal of the American Nutrition Association · 2023
    Randomized trial64 participantsGeneral Health forCollagen
  50. The use of a collagen matrix in hard-to-heal venous leg ulcers.
    Romanelli M; Mulder G; Paggi B; Macchia M; Panduri S; Dini V · Journal of wound care · 2016
    Randomized trial40 participantsGeneral Health forCollagen
  51. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  52. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  53. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  54. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  55. Low-Molecular-Weight Collagen Peptide Supplementation Improves Cellulite Severity, Skin Elasticity, and Hair Shaft Diameter: A Clinical Study with Pharmacokinetic Evaluation.
    Hwang S; Won J; Kim S; Kang W; Park M · Journal of medicinal food · 2026
    Randomized trial114 participantsHair Health forCollagen
  56. Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women-A Randomized Controlled Study.
    Duangjai A; Srivilai J; Nangola S; Amornlerdpison D · Clinics and practice · 2025
    Randomized trialHair Health forCollagen
  57. Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing.
    Biełach-Bazyluk A; Jurga M; Flisiak I; Zbroch E · Nutrients · 2026
    Narrative reviewHair Health forCollagen
  58. A Meta-Analysis of the Impact of Resveratrol Supplementation on Markers of Renal Function and Blood Pressure in Type 2 Diabetic Patients on Hypoglycemic Therapy.
    Nyambuya TM; Nkambule BB; Mazibuko-Mbeje SE; Mxinwa V; Mokgalaboni K; Orlando P; Silvestri S; Louw J; Tiano L; Dludla PV · Molecules (Basel, Switzerland) · 2021
    Meta-analysis388 participants5 studies pooledHeart Health forResveratrol
  59. Resveratrol Improves Heart Function by Moderating Inflammatory Processes in Patients with Systolic Heart Failure.
    Gal R; Deres L; Horvath O; Eros K; Sandor B; Urban P; Soos S; Marton Z; Sumegi B; Toth K; Habon T; Halmosi R · Antioxidants (Basel, Switzerland) · 2024
    Randomized trial60 participantsHeart Health forResveratrol
  60. Low dose resveratrol improves cerebrovascular function in type 2 diabetes mellitus.
    Wong RH; Nealon RS; Scholey A; Howe PR · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial36 participantsHeart Health forResveratrol
  61. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment.
    Fujitaka K; Otani H; Jo F; Jo H; Nomura E; Iwasaki M; Nishikawa M; Iwasaka T; Das DK · Nutrition research (New York, N.Y.) · 2012
    Randomized trial34 participantsHeart Health forResveratrol
  62. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  63. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.
    Zhu X; Wu C; Qiu S; Yuan X; Li L · Nutrition & metabolism · 2022
    Meta-analysis283 participants9 studies pooledMetabolism Boost forResveratrol
  64. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
    Sun JN; Yang R; Fang L; Li YJ; Xing WY; Sun ML; Wu L; Wu QJ; Gong TT · Nutrition journal · 2026
    Meta-analysis45 studies pooledMetabolism Boost forResveratrol
  65. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
    Chen S; Zhao X; Ran L; Wan J; Wang X; Qin Y; Shu F; Gao Y; Yuan L; Zhang Q; Mi M · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015
    Randomized trial60 participantsMetabolism Boost forResveratrol
  66. Supplementation with resveratrol modified gut microbiota improving insulin sensitivity and lipid metabolism in subjects with obesity and insulin resistance.
    Guevara-Cruz M; Sánchez-Tapia M; Velazquez-Villegas LA; Torre-Villalvazo I; Guizar-Heredia R; Godínez-Salas E; López-Barradas A; Granados O; Torres-Villalobos G; Torres N; Tovar AR · European journal of nutrition · 2026
    Randomized trial32 participantsMetabolism Boost forResveratrol
  67. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
    Zhou Q; Wang Y; Han X; Fu S; Zhu C; Chen Q · Frontiers in physiology · 2022
    Meta-analysis1,171 participants25 studies pooledMetabolism Boost forResveratrol
  68. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
    Hexsel D; Zague V; Schunck M; Siega C; Camozzato FO; Oesser S · Journal of cosmetic dermatology · 2018
    Single-arm trial25 participantsNail Health forCollagen
  69. Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial.
    Vleminckx S; Virgilio N; Asserin J; Prawitt J; Silva CIF · Journal of cosmetic dermatology · 2024
    Randomized trial85 participantsNail Health forCollagen
  70. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forCollagen
  71. Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.
    Kern JS; Kohlhase J; Bruckner-Tuderman L; Has C · The Journal of investigative dermatology · 2006
    Observational study41 participantsNail Health forCollagen
  72. Exploring the Impact of Hydrolyzed Collagen Oral Supplementation on Skin Rejuvenation: A Systematic Review and Meta-Analysis.
    Dewi DAR; Arimuko A; Norawati L; Yenny SW; Setiasih NL; Perdiyana A; Arkania N; Nadhira F; Wiliantari N · Cureus · 2024
    Meta-analysis967 participants14 studies pooledSkin Health forCollagen
  73. Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
    Danessa G; Notario D; Regina R · Indian journal of dermatology, venereology and leprology · 2025
    Meta-analysis646 participants10 studies pooledSkin Health forCollagen
  74. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study.
    Kim DU; Chung HC; Choi J; Sakai Y; Lee BY · Nutrients · 2018
    Randomized trial64 participantsSkin Health forCollagen
  75. Efficacy and safety of Resveratrol combined with Ablative Fractional CO2 laser system in the treatment of skin photoaging.
    Du YM; Zeng J; Li M; Wang YB; Wu Y; Qi RQ; Gao XH; Chen HD · Journal of cosmetic dermatology · 2021
    Non-randomized trial32 participantsSkin Health forResveratrol
  76. Exploring resveratrol-enriched collagen dressings for diabetic foot ulcers: A retrospective study of wound healing outcomes.
    Sezikli İ; Kendirci M · Journal of tissue viability · 2025
    Cohort study41 participantsSkin Health forResveratrol
  77. Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
    Moyano-Mendez JR; Fabbrocini G; De Stefano D; Mazzella C; Mayol L; Scognamiglio I; Carnuccio R; Ayala F; La Rotonda MI; De Rosa G · Drug development and industrial pharmacy · 2016
    Clinical trialSkin Health forResveratrol
  78. Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.
    Montenegro L; Parenti C; Turnaturi R; Pasquinucci L · Pharmaceutics · 2020
    Clinical trial12 participantsSkin Health forResveratrol