Advanced Sleep Melatonin 10 mg Time Release
Natrol
Advanced Sleep Melatonin 10 mg Time Release
4.5
★ ★ ★ ★ ★
(62726 ratings)
Melatonin 10 mg
Vitamin B6 10 mg
Score 92.0
A high-dose 10mg time-release melatonin supplement with B6 from Natrol, formulated for sustained sleep throughout the night.
Quantity: 100 Tablet(s)Servings size: 1 Tablet(s) (100 servings)
Selected goals:
Other goals:
Stress Relief
Anti-Aging
Sleep Support
Energy
Brain Health
leaderboard Score 92.0
A high-dose 10mg time-release melatonin supplement with B6 from Natrol, formulated for sustained sleep throughout the night.
Quantity: 240, Dose: 3mgQuantity: 60, Dose: 5mgQuantity: 60, Dose: 3mgQuantity: 90, Dose: 1mgQuantity: 180, Dose: 1mgQuantity: 120, Dose: 3mgQuantity: 100, Dose: 5mgQuantity: 60, Dose: 10mgQuantity: 75, Dose: 10mg
insights Analysis
The Natrol Advanced Sleep Melatonin 10 mg Time Release is specifically designed for individuals who not only have trouble falling asleep but also waking up during the night. The 10mg melatonin dose is high, providing a strong signal for sleep, while the time-release mechanism ensures a gradual release of melatonin over several hours, helping to maintain sleep throughout the night. It also includes 10mg of Pyridoxine Hydrochloride (Vitamin B6), which aids in neurotransmitter production relevant to sleep and mood. This product is highly popular, with a very large number of reviews praising its effectiveness for deep and sustained sleep, making it a top contender for advanced sleep support.
- Time-release technology is highly effective for individuals who struggle with waking up in the middle of the night.
- High 10mg melatonin dose provides strong sleep induction for those with more significant sleep challenges.
- Includes Vitamin B6, which supports natural melatonin synthesis and nervous system health.
- Extremely high review count (over 60,000) strongly indicates widespread user satisfaction and efficacy.
- From Natrol, a leading and reputable brand in sleep aids, known for quality products.
- The 10mg dose may be too high for many individuals, potentially leading to morning grogginess, vivid dreams, or tolerance issues.
- The Vitamin B6 is in the pyridoxine hydrochloride form, which some users may find less bioavailable than P-5-P.
- The time-release aspect might not be necessary for all users, especially those whose primary issue is sleep onset only.
$17.32($0.17 per serving)
 iHerb | $ 17.32 | |
 Amazon | $ 17.32 | |
 Vitacost | $ 17.49 | |
 Walmart | $ 20.40 |
bolt Effectiveness for goals
Melatonin is commonly used to help with sleep difficulties, particularly for primary insomnia or when the body's internal clock is disrupted. It may help reduce the time it takes to fall asleep and can improve overall sleep quality for some individuals. Its effectiveness can vary depending on the specific sleep issue.
Pyridoxine, the active form of Vitamin B6, is often recommended and can be effective for reducing nausea and vomiting during pregnancy, commonly known as morning sickness. It is considered a first-line treatment option, often combined with doxylamine. Its effectiveness has been demonstrated in multiple clinical studies.
Vitamin B6 plays a crucial role in nerve function and the production of neurotransmitters. It is essential for maintaining a healthy nervous system and can be used to manage certain types of neuropathy, particularly those caused by B6 deficiency. Adequate B6 intake supports overall neurological health.
Melatonin has been shown to be effective in reducing jet lag symptoms, especially when traveling across multiple time zones. It can help resynchronize the body's circadian rhythm to the new time zone. Timing of administration relative to the new time zone is crucial for optimal effect.
Vitamin B6 is involved in the synthesis of neurotransmitters like serotonin and dopamine, which influence mood. Some research suggests a potential link between B6 levels and mood regulation, but it is not a primary treatment for mood disorders. Its effectiveness for mood is often considered in the context of overall nutritional status.
schedule Dosage, timing & forms
Melatonin is generally recommended to be taken about 30 minutes to 2 hours before your intended bedtime. This allows time for the supplement to be absorbed and begin its effect. Consistency in timing is often suggested for best results.
Yes, excessive intake of Vitamin B6, particularly from supplements, can lead to nerve damage, a condition known as peripheral neuropathy. This risk increases with prolonged use of doses significantly above the tolerable upper intake level (UL) of 100 mg per day for adults. Symptoms can include numbness, tingling, and pain in the extremities.
Typical dosages for melatonin in adults generally range from 0.5 mg to 5 mg, though some products may offer higher amounts. It is often recommended to start with the lowest effective dose. Dosages can vary based on individual needs and the specific reason for use.
For adults, the recommended daily allowance (RDA) for Vitamin B6 is 1.3-1.7 mg, but supplements often contain higher amounts, such as 10-100 mg. It is important not to exceed the tolerable upper intake level (UL) of 100 mg per day for adults to avoid potential side effects. Higher doses are sometimes used under professional guidance for specific conditions.
While short-term use of melatonin at common dosages is generally considered safe, the long-term safety of high doses has not been extensively studied. Prolonged use, especially at higher amounts, may potentially disrupt the body's natural melatonin production or lead to side effects. It is best to use the lowest effective dose and discuss long-term use with a healthcare professional.
health_and_safety Safety & interactions
Melatonin can interact with several medications, including anticoagulants, immunosuppressants, diabetes medications, and some antidepressants. It may also increase the effects of sedatives, potentially causing excessive drowsiness. Always discuss supplement use with a healthcare provider, especially if taking other medications.
Common side effects of melatonin can include daytime drowsiness, dizziness, headache, and nausea. Some individuals may also experience vivid dreams or temporary feelings of depression. These effects are generally mild and temporary.
The long-term safety of melatonin use is not fully established. While generally considered safe for short-term use, some studies suggest potential effects on the body's natural melatonin production or hormone balance with prolonged use. It is advisable to consult a healthcare professional regarding long-term use.
At recommended doses, Vitamin B6 is generally considered safe. However, high doses, typically exceeding 200 mg/day over long periods, can lead to nerve damage. Symptoms may include numbness, tingling, and difficulty walking.
Due to limited research and safety data, melatonin is generally not recommended for use during pregnancy or breastfeeding. The potential effects on fetal development or infant health are not well understood. It is best to consult a healthcare professional before considering its use in these periods.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 10 mg |
Calcium | 23 mg |
Melatonin | 10 mg |
Categories
Melatonin 95.0
The 10mg dose combined with time-release technology makes this an advanced and highly effective melatonin product for comprehensive sleep support, particularly for those needing help staying asleep. Natrol's reputation further solidifies its standing.
Vitamin B6 75.0
The 10mg dose of Vitamin B6 is beneficial for supporting neurotransmitter production and overall nervous system health, which can aid in sleep and mood. However, the use of pyridoxine hydrochloride instead of the more bioavailable pyridoxal 5'-phosphate (P-5-P) means it may not be optimally absorbed by everyone.
Goals
Sleep Support 98.0
This product excels in sleep support due to its high 10mg melatonin dose and crucial time-release technology, addressing both sleep onset and maintenance for a comprehensive solution. The added B6 further enhances the body's natural sleep processes, making it highly effective.
Stress Relief 85.0
By promoting deep and sustained sleep, this product significantly contributes to stress reduction, as quality rest is paramount for the body's ability to recover from and cope with daily stressors. Vitamin B6 also plays a direct role in neurotransmitter production linked to stress management.
Mood Support 80.0
Restorative sleep is fundamental for mood regulation, leading to reduced irritability and enhanced emotional well-being. The inclusion of Vitamin B6 supports the synthesis of key mood-regulating neurotransmitters like serotonin, providing a direct boost to mood.
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