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Melatonin Advanced 10 mg Time Release

Natrol
4.6
★ ★ ★ ★ ★
(33275 ratings)
Melatonin 10 mg
Product Image
Score76
Useful time-release design is offset by a high 10 mg amount that may produce more next-day effects than many users want.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
Sleep Support

Score 76

Useful time-release design is offset by a high 10 mg amount that may produce more next-day effects than many users want.
How scoring works

Also available as

8 options
3.00mg • 240 Tablet(s) servings Melatonin 3 mg • 240 Tablet(s) • 240 servings $12.99 ($0.05 per serving) 1.00mg • 180 Tablet(s) servings Melatonin 1 mg • 180 Tablet(s) • 180 servings $11.24 ($0.06 per serving) 3.00mg • 120 Tablet(s) servings Melatonin 3 mg • 120 Tablet(s) • 120 servings $8.32 ($0.06 per serving) 1.00mg • 90 Tablet(s) servings Melatonin 1 mg • 90 Tablet(s) • 90 servings $6.99 ($0.07 per serving) 75 servings Melatonin 10 mg • 75 Tablet(s) • 75 servings $8.96 ($0.11 per serving) 100 servings Melatonin 10 mg • 100 Tablet(s) • 100 servings $11.95 ($0.11 per serving) 3.00mg • 60 Tablet(s) servings Melatonin 3 mg • 60 Tablet(s) • 60 servings $7.79 ($0.12 per serving) 5.00mg • 60 Tablet(s) servings Melatonin 5 mg • 60 Tablet(s) • 60 servings $8.84 ($0.14 per serving)
$8.97($0.14 per serving)
Pure Formulas
$ 10.32
iHerb
$ 12.12
Vitacost
$ 12.79
Amazon
$ 9.00
Walmart
$ 8.97
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Analysis

The time-release tablet can extend melatonin exposure beyond sleep onset and may suit people whose difficulty continues through the night. That delivery advantage is meaningful compared with standard immediate-release tablets.

A 10 mg amount is still high and may keep some users exposed longer than needed. The 10 mg of vitamin B6 and 23 mg of calcium do not establish a separate, substantial sleep-support pathway.

The product fits adults who specifically need overnight release and have already found lower amounts insufficient. Users sensitive to next-day sedation should be especially cautious because both the high dose and gradual delivery can carry effects into the morning.

Who is it for
  • Adults seeking melatonin release across the night
  • Experienced users who have a reason for a 10 mg amount
Best for
  • Sleep maintenance as well as onset
  • A gradual-release bedtime routine

Pros

  • Uses time-release delivery
  • Clearly provides 10 mg of melatonin
  • Offers 60 servings

Cons

  • The amount is high for many users
  • Vitamin B6 and calcium add little sleep-pathway depth
  • High dose may extend unwanted morning effects

Warnings

  • Melatonin can cause drowsiness or next-day grogginess, so it should not be taken before driving or another task that requires alertness.
  • The 10 mg time-release serving may increase vivid dreams, headache, or next-morning grogginess.

Nutrient quality

69 High impact

Time-release delivery may better support overnight maintenance. The high amount creates the main quality weakness through greater next-day drowsiness risk.

Ingredient transparency

84 Highest impact

The shown active ingredients have clear amounts and no proprietary blend hides a key dose. Daily directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

70 High impact

The supplied aggregate rating is favorable and supported by an exceptionally large review volume. Detailed feedback is unavailable, so repeated complaints and fit with the intended use cannot be judged.

Value for money

78 High impact

The formula provides strong practical value for its dose and delivery features. Secondary ingredients or delivery extras reduce category competitiveness.

Report analysis

Goals

Sleep Support
Sleep Support
Impact
High effect
A+ Goal FitB- Strength of SupportC- CoverageB- Formula Quality
Melatonin · 10 mg

Time-release melatonin directly supports circadian signaling and may extend support through the night. The 10 mg amount is much higher than the low physiological range and may be more than many users need.

Clear disclosure and sustained delivery make the intended sleep-maintenance role easy to understand. The high melatonin dose can increase morning grogginess or vivid dreams, while the added vitamin B6 has limited value as a separate sleep pathway.

Study evidence
Melatonin Supportive 181 studies
Vitamin B6 Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 10 mg
Calcium (Dibasic Calcium Phosphate)
 23 mg
Melatonin
10 mg
Adults 18–50 Dairy Free Children 4+ Vegetarian
Report overview
Melatonin · 10 mg OverallScore57
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyA- Value

The time-release tablet supports overnight maintenance and has no supplied independent purity certification. The high melatonin amount may increase the chance of morning grogginess. The moderate serving cost supports its value.

View ingredientView products
Loading alternative details
88 Performance

Melatonin 1.0 mg Orange Flavor

Source Naturals Sleep Science
<p>It improves the ingredient-quality case with a conservative 1 mg melatonin amount and a dissolving format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
86 Performance

Melatonin 1 mg Fast Dissolve Strawberry Natural Flavor

Natrol
<p>It improves the ingredient-quality case with a conservative 1 mg melatonin amount and a dissolving format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
87 Performance

Melatonin Lozenges 3 mg

Life Extension
<p>It improves the ingredient-quality case with a practical 3 mg melatonin amount and a dissolving lozenge. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
87 Budget

Melatonin 1 mg

Nature's Bounty
<p>It lowers recurring cost while providing a conservative 1 mg melatonin amount through a straightforward immediate-release format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
84 Budget

Melatonin 1 mg

Spring Valley
<p>It lowers recurring cost while providing a conservative 1 mg melatonin amount through a straightforward immediate-release format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
83 Budget

Melatonin 3 mg

Nature Made
<p>It lowers recurring cost while providing a practical 3 mg melatonin amount through a straightforward immediate-release format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
88 Value

Melatonin 1.0 mg Peppermint Flavor

Source Naturals Sleep Science
<p>It balances strong serving value with a conservative 1 mg melatonin amount and a dissolving format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
86 Value

Fast-Dissolve Melatonin 3 mg Artificial Strawberry Flavor

Spring Valley
<p>It balances strong serving value with a practical 3 mg melatonin amount and a dissolving format. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
86 Value

Melatonin Lozenge 2.5 mg

Nature's Way
<p>It balances strong serving value with a practical 2.5 mg melatonin amount and a dissolving lozenge. Compared with Melatonin Advanced 10 mg Time Release, it is better suited to sleep onset and uses a lower amount, but it gives up the original's overnight-release feature.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  4. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  5. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  6. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  7. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  8. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  9. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  10. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  11. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6