Melatonin Advanced 10 mg Time Release
Natrol
Melatonin Advanced 10 mg Time Release
4.6
★ ★ ★ ★ ★
(31363 ratings)
Melatonin 10 mg
Vitamin B6 10 mg
Score 80.0
A potent 10mg time-release melatonin from Natrol, ideal for severe sleep issues requiring strong, sustained support.
Quantity: 60 Tablet(s)Servings size: 1 Tablet(s) (60 servings)
Selected goals:
Other goals:
Stress Relief
Anti-Aging
Sleep Support
Energy
Brain Health
leaderboard Score 80.0
A potent 10mg time-release melatonin from Natrol, ideal for severe sleep issues requiring strong, sustained support.
Quantity: 240, Dose: 3mgQuantity: 60, Dose: 5mgQuantity: 60, Dose: 3mgQuantity: 90, Dose: 1mgQuantity: 180, Dose: 1mgQuantity: 120, Dose: 3mgQuantity: 100, Dose: 5mgQuantity: 75, Dose: 10mgQuantity: 100, Dose: 10mg
insights Analysis
Natrol Melatonin Advanced 10 mg Time Release is a high-dose melatonin product explicitly designed for individuals with significant sleep challenges, particularly those who struggle with both falling asleep and staying asleep through the night. The time-release formulation is crucial for sustaining melatonin levels throughout the night, mimicking the body's natural production cycle and promoting deeper, more restorative sleep. The standard 10mg of Vitamin B6 is included, providing minor synergistic support for the nervous system, but the product's primary strength lies in its high melatonin potency. The considerable number of positive reviews highlights its effectiveness for its target audience seeking robust sleep intervention.
- Offers a high 10mg dose for maximum efficacy in severe sleep onset and maintenance issues.
- Time-release mechanism ensures sustained melatonin levels throughout the night, preventing premature waking.
- Highly reviewed by users with persistent sleep problems, indicating its effectiveness for its target demographic.
- Includes Vitamin B6, providing some supportive benefits for the nervous system and mood.
- The 10mg dose is very high and may cause excessive grogginess, lethargy, or rebound insomnia in individuals not requiring such a strong effect.
- Relatively high price per serving compared to lower-dose or immediate-release melatonin alternatives.
- Limited direct contribution to broader health goals like 'Energy' or 'Anti-Aging' beyond the indirect benefits of improved sleep.
$9.65($0.16 per serving)
 Amazon | $ 9.65 | |
 Vitacost | $ 10.79 | |
 iHerb | $ 12.12 | |
 Walmart | $ 17.97 |
bolt Effectiveness for goals
Melatonin is commonly used to help with sleep difficulties, particularly for primary insomnia or when the body's internal clock is disrupted. It may help reduce the time it takes to fall asleep and can improve overall sleep quality for some individuals. Its effectiveness can vary depending on the specific sleep issue.
Pyridoxine, the active form of Vitamin B6, is often recommended and can be effective for reducing nausea and vomiting during pregnancy, commonly known as morning sickness. It is considered a first-line treatment option, often combined with doxylamine. Its effectiveness has been demonstrated in multiple clinical studies.
Vitamin B6 plays a crucial role in nerve function and the production of neurotransmitters. It is essential for maintaining a healthy nervous system and can be used to manage certain types of neuropathy, particularly those caused by B6 deficiency. Adequate B6 intake supports overall neurological health.
Melatonin has been shown to be effective in reducing jet lag symptoms, especially when traveling across multiple time zones. It can help resynchronize the body's circadian rhythm to the new time zone. Timing of administration relative to the new time zone is crucial for optimal effect.
Vitamin B6 is involved in the synthesis of neurotransmitters like serotonin and dopamine, which influence mood. Some research suggests a potential link between B6 levels and mood regulation, but it is not a primary treatment for mood disorders. Its effectiveness for mood is often considered in the context of overall nutritional status.
schedule Dosage, timing & forms
Melatonin is generally recommended to be taken about 30 minutes to 2 hours before your intended bedtime. This allows time for the supplement to be absorbed and begin its effect. Consistency in timing is often suggested for best results.
Yes, excessive intake of Vitamin B6, particularly from supplements, can lead to nerve damage, a condition known as peripheral neuropathy. This risk increases with prolonged use of doses significantly above the tolerable upper intake level (UL) of 100 mg per day for adults. Symptoms can include numbness, tingling, and pain in the extremities.
Typical dosages for melatonin in adults generally range from 0.5 mg to 5 mg, though some products may offer higher amounts. It is often recommended to start with the lowest effective dose. Dosages can vary based on individual needs and the specific reason for use.
For adults, the recommended daily allowance (RDA) for Vitamin B6 is 1.3-1.7 mg, but supplements often contain higher amounts, such as 10-100 mg. It is important not to exceed the tolerable upper intake level (UL) of 100 mg per day for adults to avoid potential side effects. Higher doses are sometimes used under professional guidance for specific conditions.
While short-term use of melatonin at common dosages is generally considered safe, the long-term safety of high doses has not been extensively studied. Prolonged use, especially at higher amounts, may potentially disrupt the body's natural melatonin production or lead to side effects. It is best to use the lowest effective dose and discuss long-term use with a healthcare professional.
health_and_safety Safety & interactions
Melatonin can interact with several medications, including anticoagulants, immunosuppressants, diabetes medications, and some antidepressants. It may also increase the effects of sedatives, potentially causing excessive drowsiness. Always discuss supplement use with a healthcare provider, especially if taking other medications.
Common side effects of melatonin can include daytime drowsiness, dizziness, headache, and nausea. Some individuals may also experience vivid dreams or temporary feelings of depression. These effects are generally mild and temporary.
The long-term safety of melatonin use is not fully established. While generally considered safe for short-term use, some studies suggest potential effects on the body's natural melatonin production or hormone balance with prolonged use. It is advisable to consult a healthcare professional regarding long-term use.
At recommended doses, Vitamin B6 is generally considered safe. However, high doses, typically exceeding 200 mg/day over long periods, can lead to nerve damage. Symptoms may include numbness, tingling, and difficulty walking.
Due to limited research and safety data, melatonin is generally not recommended for use during pregnancy or breastfeeding. The potential effects on fetal development or infant health are not well understood. It is best to consult a healthcare professional before considering its use in these periods.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 10 mg |
Calcium | 23 mg |
Melatonin | 10 mg |
Categories
Melatonin 90.0
The 10mg dose with time-release is highly potent and effective for severe sleep disturbances, offering prolonged sleep maintenance, though it might be excessive for some.
Vitamin B6 50.0
The 10mg dose of Pyridoxine Hydrochloride is a standard supplementary amount, providing general nervous system support rather than high-dose therapeutic benefits.
Goals
Sleep Support 90.0
The 10mg time-release dose is very effective for severe sleep onset and maintenance issues, though this high dose might exceed what many individuals require.
Stress Relief 65.0
Consistent and profound sleep significantly mitigates chronic stress, with B6 offering additional support for a calmer nervous system.
Mood Support 65.0
Deep, restorative sleep is vital for emotional regulation and psychological well-being, and B6 can further contribute to balanced neurotransmitter levels.
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